Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Polyphosphate kinase

Gene

ppk

Organism
Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).UniRule annotation

Catalytic activityi

ATP + (phosphate)(n) = ADP + (phosphate)(n+1).UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei91ATPUniRule annotation1
Metal bindingi421MagnesiumUniRule annotation1
Metal bindingi451MagnesiumUniRule annotation1
Active sitei481Phosphohistidine intermediateUniRule annotation1
Binding sitei514ATPUniRule annotation1
Binding sitei610ATPUniRule annotation1
Binding sitei638ATPUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPSYR223283:G1G0D-5319-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Polyphosphate kinaseUniRule annotation (EC:2.7.4.1UniRule annotation)
Alternative name(s):
ATP-polyphosphate phosphotransferaseUniRule annotation
Polyphosphoric acid kinaseUniRule annotation
Gene namesi
Name:ppkUniRule annotation
Ordered Locus Names:PSPTO_5250
OrganismiPseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Taxonomic identifieri223283 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002515 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001286541 – 736Polyphosphate kinaseAdd BLAST736

Post-translational modificationi

An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.UniRule annotation

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiQ87UP6

Interactioni

Protein-protein interaction databases

STRINGi223283.PSPTO_5250

Structurei

3D structure databases

ProteinModelPortaliQ87UP6
SMRiQ87UP6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the polyphosphate kinase 1 (PPK1) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CUU Bacteria
COG0855 LUCA
HOGENOMiHOG000248948
KOiK00937
OMAiQIMVANL
OrthoDBiPOG091H02MN
PhylomeDBiQ87UP6

Family and domain databases

Gene3Di3.30.1840.10, 1 hit
HAMAPiMF_00347 Polyphosphate_kinase, 1 hit
InterProiView protein in InterPro
IPR003414 PP_kinase
IPR024953 PP_kinase_middle
IPR036830 PP_kinase_middle_dom_sf
IPR025200 PPK_C_dom
IPR025198 PPK_N_dom
IPR036832 PPK_N_dom_sf
PANTHERiPTHR30218 PTHR30218, 1 hit
PfamiView protein in Pfam
PF02503 PP_kinase, 1 hit
PF13090 PP_kinase_C, 1 hit
PF13089 PP_kinase_N, 1 hit
PIRSFiPIRSF015589 PP_kinase, 1 hit
SUPFAMiSSF140356 SSF140356, 1 hit
TIGRFAMsiTIGR03705 poly_P_kin, 1 hit

Sequencei

Sequence statusi: Complete.

Q87UP6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNTEALIEAA VEVDVQEAAP VVEPDIEVIP AIEAPAASLP AIVAPNLDDS
60 70 80 90 100
SLYIHRELSQ LQFNIRVLEQ ALDESYPLLE RLKFLLIFSS NLDEFFEIRV
110 120 130 140 150
AGLKKQITFA REQAGADGLQ PHQALARISE LVHGHVDRQY AILNDILLPE
160 170 180 190 200
LEKHQVRFIR RRHWTAKLKA WVRRYFRDEI APIITPIGLD PTHPFPLLVN
210 220 230 240 250
KSLNFIVELE GIDAFGRDSG LAIIPAPRLL PRVIKVPEEV CGPGDNFVFL
260 270 280 290 300
SSMIHAHADD LFQGMKVKGC YQFRLTRNAD LALDSEDVED LARALRGELF
310 320 330 340 350
SRRYGDAVRL EVADTCPKHL SDYLLKQFNL HESELYQVNG PVNLTRLFSI
360 370 380 390 400
TGLDSHPELQ YPPFTPAIPK LLQNSENVFS VVSKQDILLL HPFESFTPVV
410 420 430 440 450
DLLRQAAKDP HVLAVRQTLY RSGANSEIVD ALVDAARNGK EVTAVIELRA
460 470 480 490 500
RFDEESNLQL ASRLQAAGAV VIYGVVGFKT HAKMMLILRR EAGEIVRYAH
510 520 530 540 550
LGTGNYHAGN ARLYTDYSLL TSDDALCEDV GKLFSQLIGM GKTLRMKKLL
560 570 580 590 600
HAPFTLKKGM LDMIARETQF ALDGKPAHII AKFNSLTDPK IIRALYKASQ
610 620 630 640 650
SGVRIDLVVR GMCCLRPGIA GVSHNIHVRS IIGRFLEHTR VFYFLNGGDE
660 670 680 690 700
QMFLSSADWM ERNLDKRVET CFPVEGKKLI LRVKKELESY LTDNTHSWLL
710 720 730
QSDGRYVRSM PTGNQNARSA QATLLERLSN PVLSVR
Length:736
Mass (Da):82,692
Last modified:June 1, 2003 - v1
Checksum:iEE471CE7FBB49E00
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016853 Genomic DNA Translation: AAO58676.1
RefSeqiNP_794981.1, NC_004578.1
WP_005768431.1, NC_004578.1

Genome annotation databases

EnsemblBacteriaiAAO58676; AAO58676; PSPTO_5250
GeneIDi1186935
KEGGipst:PSPTO_5250
PATRICifig|223283.9.peg.5373

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016853 Genomic DNA Translation: AAO58676.1
RefSeqiNP_794981.1, NC_004578.1
WP_005768431.1, NC_004578.1

3D structure databases

ProteinModelPortaliQ87UP6
SMRiQ87UP6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi223283.PSPTO_5250

Proteomic databases

PRIDEiQ87UP6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAO58676; AAO58676; PSPTO_5250
GeneIDi1186935
KEGGipst:PSPTO_5250
PATRICifig|223283.9.peg.5373

Phylogenomic databases

eggNOGiENOG4105CUU Bacteria
COG0855 LUCA
HOGENOMiHOG000248948
KOiK00937
OMAiQIMVANL
OrthoDBiPOG091H02MN
PhylomeDBiQ87UP6

Enzyme and pathway databases

BioCyciPSYR223283:G1G0D-5319-MONOMER

Family and domain databases

Gene3Di3.30.1840.10, 1 hit
HAMAPiMF_00347 Polyphosphate_kinase, 1 hit
InterProiView protein in InterPro
IPR003414 PP_kinase
IPR024953 PP_kinase_middle
IPR036830 PP_kinase_middle_dom_sf
IPR025200 PPK_C_dom
IPR025198 PPK_N_dom
IPR036832 PPK_N_dom_sf
PANTHERiPTHR30218 PTHR30218, 1 hit
PfamiView protein in Pfam
PF02503 PP_kinase, 1 hit
PF13090 PP_kinase_C, 1 hit
PF13089 PP_kinase_N, 1 hit
PIRSFiPIRSF015589 PP_kinase, 1 hit
SUPFAMiSSF140356 SSF140356, 1 hit
TIGRFAMsiTIGR03705 poly_P_kin, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPPK1_PSESM
AccessioniPrimary (citable) accession number: Q87UP6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2003
Last sequence update: June 1, 2003
Last modified: May 23, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again