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Entry version 95 (02 Jun 2021)
Sequence version 1 (01 Jun 2003)
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Protein

Membrane protein insertase YidC

Gene

yidC

Organism
Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

UniRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChaperone
Biological processProtein transport, Transport

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
PSYR223283:G1G0D-5689-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Membrane protein insertase YidCUniRule annotation
Alternative name(s):
Foldase YidCUniRule annotation
Membrane integrase YidCUniRule annotation
Membrane protein YidCUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:yidCUniRule annotation
Ordered Locus Names:PSPTO_5612
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri223283 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002515 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1 – 21HelicalUniRule annotationAdd BLAST21
Transmembranei343 – 363HelicalUniRule annotationAdd BLAST21
Transmembranei369 – 389HelicalUniRule annotationAdd BLAST21
Transmembranei439 – 459HelicalUniRule annotationAdd BLAST21
Transmembranei470 – 490HelicalUniRule annotationAdd BLAST21
Transmembranei517 – 537HelicalUniRule annotationAdd BLAST21

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001247441 – 562Membrane protein insertase YidCAdd BLAST562

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q87TS1

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.

UniRule annotation

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
223283.PSPTO_5612

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q87TS1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni42 – 74DisorderedSequence analysisAdd BLAST33

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG0706, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_016535_3_0_6

Identification of Orthologs from Complete Genome Data

More...
OMAi
INPVAGC

Database of Orthologous Groups

More...
OrthoDBi
524437at2

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q87TS1

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.70.98.90, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_01810, YidC_type1, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019998, Membr_insert_YidC
IPR028055, Membr_insert_YidC/Oxa1_C
IPR028053, Membr_insert_YidC_N
IPR001708, YidC/ALB3/OXA1/COX18
IPR038210, YidC_periplasmic
IPR038221, YidC_periplasmic_sf

The PANTHER Classification System

More...
PANTHERi
PTHR12428, PTHR12428, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02096, 60KD_IMP, 1 hit
PF14849, YidC_periplas, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00701, 60KDINNERMP
PR01900, YIDCPROTEIN

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03593, yidC_nterm, 1 hit
TIGR03592, yidC_oxa1_cterm, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q87TS1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDIKRTILIV ALAIVTYVGV LKWNQDYGQA AMPTQNVAAS NTAPGIPDTA
60 70 80 90 100
AGNNGSASAD VPSATGNTTS AAPLETPAVA SKDLIHVKTD VLDLAIDPVG
110 120 130 140 150
GDVVQLRLPL YPRRQDRPDV PFQLFDNGGE RTFLAQSGLT GTNGPDARAS
160 170 180 190 200
GRPVYSSAQK SYQLADGQDS MVVELKFSEN GVNYIKRFTF KRGLYDLVMT
210 220 230 240 250
YVVDNQSAQP WAGNLFAQLK RDASSDPSST TATGTATYLG AALWTAAEPY
260 270 280 290 300
KKVSMKDIDK GQIKENVQGG WVAWLQHYFV TAWIPDHNVT NAVQTRKDSQ
310 320 330 340 350
GNYIIGFTSP TLSVAPGAQG ETTATLYAGP KSQAVLKELS PGLELTVDYG
360 370 380 390 400
FLWFIAQPIF WLLQHIHAIL GNWGWSIIVL TMLIKGLFFP LSAASYKSMA
410 420 430 440 450
RMRAVAPKLA VLKEQHGDDR QKMSQAMMEL YKKEKINPLG GCLPILVQMP
460 470 480 490 500
VFLSLYWVLL ESVEMRQAPW ILWITDLSIK DPFFILPIIM GATMFIQQRL
510 520 530 540 550
NPTPPDPMQA KVMKMMPIIF TFFFLWFPAG LVLYWVVNNT LSIAQQAYIT
560
RKIGAATKKA AA
Length:562
Mass (Da):61,766
Last modified:June 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE18CC4955078C0AF
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE016853 Genomic DNA Translation: AAO59025.1

NCBI Reference Sequences

More...
RefSeqi
NP_795330.1, NC_004578.1
WP_011105595.1, NC_004578.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAO59025; AAO59025; PSPTO_5612

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
1187304

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
pst:PSPTO_5612

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|223283.9.peg.5749

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016853 Genomic DNA Translation: AAO59025.1
RefSeqiNP_795330.1, NC_004578.1
WP_011105595.1, NC_004578.1

3D structure databases

SMRiQ87TS1
ModBaseiSearch...

Protein-protein interaction databases

STRINGi223283.PSPTO_5612

Proteomic databases

PRIDEiQ87TS1

Genome annotation databases

EnsemblBacteriaiAAO59025; AAO59025; PSPTO_5612
GeneIDi1187304
KEGGipst:PSPTO_5612
PATRICifig|223283.9.peg.5749

Phylogenomic databases

eggNOGiCOG0706, Bacteria
HOGENOMiCLU_016535_3_0_6
OMAiINPVAGC
OrthoDBi524437at2
PhylomeDBiQ87TS1

Enzyme and pathway databases

BioCyciPSYR223283:G1G0D-5689-MONOMER

Family and domain databases

Gene3Di2.70.98.90, 1 hit
HAMAPiMF_01810, YidC_type1, 1 hit
InterProiView protein in InterPro
IPR019998, Membr_insert_YidC
IPR028055, Membr_insert_YidC/Oxa1_C
IPR028053, Membr_insert_YidC_N
IPR001708, YidC/ALB3/OXA1/COX18
IPR038210, YidC_periplasmic
IPR038221, YidC_periplasmic_sf
PANTHERiPTHR12428, PTHR12428, 1 hit
PfamiView protein in Pfam
PF02096, 60KD_IMP, 1 hit
PF14849, YidC_periplas, 1 hit
PRINTSiPR00701, 60KDINNERMP
PR01900, YIDCPROTEIN
TIGRFAMsiTIGR03593, yidC_nterm, 1 hit
TIGR03592, yidC_oxa1_cterm, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYIDC_PSESM
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q87TS1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 21, 2003
Last sequence update: June 1, 2003
Last modified: June 2, 2021
This is version 95 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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