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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciVPAR223926:G1GTB-902-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:VP0861
OrganismiVibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Taxonomic identifieri223926 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000002493 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001516331 – 577Arginine--tRNA ligaseAdd BLAST577

Proteomic databases

PRIDEiQ87RD6

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi223926.VP0861

Structurei

3D structure databases

ProteinModelPortaliQ87RD6
SMRiQ87RD6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi122 – 132"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247212
KOiK01887
OMAiNKPLHLG

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q87RD6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIQALINDK VSQALEAAGA PAGSPAAVRQ SAKPQFGDYQ ANGVMGVAKK
60 70 80 90 100
LGTNPREFAQ KVLDVLDLDG IASKTEIAGP GFINIFLSEE FLAKQADAAL
110 120 130 140 150
ADSRLGVAAE EAQTIVADYS APNVAKEMHV GHLRSTIIGD AVVRTLEFLG
160 170 180 190 200
HKVIRANHIG DWGTQFGMLI ANLERVQQES GEVSMELADL EGFYRESKKL
210 220 230 240 250
YDEDEEFAVK ARNYVVKLQS GDEFCAEMWK KLVDVTMIQN QRNYDRLNVS
260 270 280 290 300
LTRDDVMGES MYNDMLPKIV ADLKAQGLAV EDDGAQVVFL EEFKNKDGEA
310 320 330 340 350
MGVIVQKRDG GFLYTTTDIA CAKYRYEELG ADRVLYFIDS RQHQHLMQAW
360 370 380 390 400
TIVRKAGYVP ESVSLEHHAF GMMLGKDGKP FKTRAGGTVR LADLLDEAEV
410 420 430 440 450
RAAQLIESKN PELDAEEKEK ISKTVAMAAV KYSDLSKHRT TDYVFDWDNM
460 470 480 490 500
LAFEGNTAPY MQYAYTRVAS IFAKAGVAMD ELQGDIQITD EKEKALIAKL
510 520 530 540 550
LQFEEAVQSV AREGQPHIMC SYLFELAGQF SSFYEACPIL VAEDEAVKQS
560 570
RLKLAALTAK TIKQGLSLLG IETLERM
Length:577
Mass (Da):63,871
Last modified:May 23, 2003 - v1
Checksum:i8BF8273F071A48D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000031 Genomic DNA Translation: BAC59124.1
RefSeqiNP_797240.1, NC_004603.1
WP_005455463.1, NC_004603.1

Genome annotation databases

EnsemblBacteriaiBAC59124; BAC59124; BAC59124
GeneIDi1188358
KEGGivpa:VP0861
PATRICifig|223926.6.peg.815

Similar proteinsi

Entry informationi

Entry nameiSYR_VIBPA
AccessioniPrimary (citable) accession number: Q87RD6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: May 23, 2003
Last modified: May 23, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

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