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Protein

Phosphocarrier protein HPr

Gene

ptsH

Organism
Xylella fastidiosa (strain Temecula1 / ATCC 700964)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.By similarity

Activity regulationi

Phosphorylation on Ser-46 inhibits the phosphoryl transfer from enzyme I to HPr.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei15Pros-phosphohistidine intermediatePROSITE-ProRule annotation1

GO - Biological processi

Keywordsi

Biological processPhosphotransferase system, Sugar transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphocarrier protein HPr
Alternative name(s):
Histidine-containing protein
Gene namesi
Name:ptsH
Ordered Locus Names:PD_0632
OrganismiXylella fastidiosa (strain Temecula1 / ATCC 700964)
Taxonomic identifieri183190 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXylella
Proteomesi
  • UP000002516 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001078891 – 89Phosphocarrier protein HPrAdd BLAST89

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei46Phosphoserine; by HPrK/PPROSITE-ProRule annotation1

Keywords - PTMi

Phosphoprotein

Structurei

3D structure databases

ProteinModelPortaliQ87DQ0
SMRiQ87DQ0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 88HPrPROSITE-ProRule annotationAdd BLAST88

Sequence similaritiesi

Belongs to the HPr family.Curated

Phylogenomic databases

KOiK11189
OMAiAEVWVTR

Family and domain databases

CDDicd00367 PTS-HPr_like, 1 hit
Gene3Di3.30.1340.10, 1 hit
InterProiView protein in InterPro
IPR000032 HPr-like
IPR035895 HPr-like_sf
IPR001020 PTS_HPr_His_P_site
IPR002114 PTS_HPr_Ser_P_site
PfamiView protein in Pfam
PF00381 PTS-HPr, 1 hit
PRINTSiPR00107 PHOSPHOCPHPR
SUPFAMiSSF55594 SSF55594, 1 hit
TIGRFAMsiTIGR01003 PTS_HPr_family, 1 hit
PROSITEiView protein in PROSITE
PS51350 PTS_HPR_DOM, 1 hit
PS00369 PTS_HPR_HIS, 1 hit
PS00589 PTS_HPR_SER, 1 hit

Sequencei

Sequence statusi: Complete.

Q87DQ0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLEHELTVTN KLGLHARATA KLVQTMSKFQ SNTTLSTKGR EVNAKSIMGV
60 70 80
MLLAASQGTV IRVRIDGEDE HTAMQALSEL FENRFNEDT
Length:89
Mass (Da):9,863
Last modified:June 16, 2003 - v1
Checksum:i5EDA9778A5910067
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009442 Genomic DNA Translation: AAO28503.1
RefSeqiWP_004089222.1, NC_004556.1

Genome annotation databases

EnsemblBacteriaiAAO28503; AAO28503; PD_0632
GeneIDi33196404
KEGGixft:PD_0632

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009442 Genomic DNA Translation: AAO28503.1
RefSeqiWP_004089222.1, NC_004556.1

3D structure databases

ProteinModelPortaliQ87DQ0
SMRiQ87DQ0
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAO28503; AAO28503; PD_0632
GeneIDi33196404
KEGGixft:PD_0632

Phylogenomic databases

KOiK11189
OMAiAEVWVTR

Family and domain databases

CDDicd00367 PTS-HPr_like, 1 hit
Gene3Di3.30.1340.10, 1 hit
InterProiView protein in InterPro
IPR000032 HPr-like
IPR035895 HPr-like_sf
IPR001020 PTS_HPr_His_P_site
IPR002114 PTS_HPr_Ser_P_site
PfamiView protein in Pfam
PF00381 PTS-HPr, 1 hit
PRINTSiPR00107 PHOSPHOCPHPR
SUPFAMiSSF55594 SSF55594, 1 hit
TIGRFAMsiTIGR01003 PTS_HPr_family, 1 hit
PROSITEiView protein in PROSITE
PS51350 PTS_HPR_DOM, 1 hit
PS00369 PTS_HPR_HIS, 1 hit
PS00589 PTS_HPR_SER, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPTHP_XYLFT
AccessioniPrimary (citable) accession number: Q87DQ0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 16, 2003
Last sequence update: June 16, 2003
Last modified: September 12, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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