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Entry version 110 (16 Oct 2019)
Sequence version 2 (25 Nov 2008)
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Protein

Coiled-coil domain-containing protein 125

Gene

CCDC125

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in the regulation of cell migration.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Coiled-coil domain-containing protein 125
Alternative name(s):
Protein kenae
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CCDC125
Synonyms:KENAE
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:28924 CCDC125

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
613781 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q86Z20

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
202243

Open Targets

More...
OpenTargetsi
ENSG00000183323

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA147358306

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q86Z20

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CCDC125

Domain mapping of disease mutations (DMDM)

More...
DMDMi
215273947

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002888121 – 511Coiled-coil domain-containing protein 125Add BLAST511

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei504PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q86Z20

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q86Z20

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q86Z20

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q86Z20

PeptideAtlas

More...
PeptideAtlasi
Q86Z20

PRoteomics IDEntifications database

More...
PRIDEi
Q86Z20

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
70497 [Q86Z20-1]
70498 [Q86Z20-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q86Z20

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q86Z20

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000183323 Expressed in 147 organ(s), highest expression level in blood

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q86Z20 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q86Z20 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA041878

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
Q7L5A34EBI-11977221,EBI-745689

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q86Z20, 66 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000379754

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q86Z20

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili105 – 243Sequence analysisAdd BLAST139
Coiled coili293 – 325Sequence analysisAdd BLAST33

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IKFY Eukaryota
ENOG410YHUF LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00440000039958

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000063705

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q86Z20

Identification of Orthologs from Complete Genome Data

More...
OMAi
EVQTWET

Database of Orthologous Groups

More...
OrthoDBi
1152075at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q86Z20

TreeFam database of animal gene trees

More...
TreeFami
TF332719

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR034608 CCDC125

The PANTHER Classification System

More...
PANTHERi
PTHR28616 PTHR28616, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q86Z20-1) [UniParc]FASTAAdd to basket
Also known as: Kenae-1

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSKVARSSSE SDVQLWETEE DDMTEGDLGY GLGRKPGGIY EIEFSHRSRK
60 70 80 90 100
RSDGKNFSPP PFPRKGEERN EASFQYSKHK SQQDTFPQVS RISNYRRQSS
110 120 130 140 150
TVDSNSELSN EELRQCLNET LEEVEMLKTE LEASQRQLRG KEEALKILQS
160 170 180 190 200
MAILGKATSH TQAVLQKTME QNRSLEKEIN ALQWEIEFDH NRFKNIEESW
210 220 230 240 250
IQKYDRLNCE NAVLKENLKV KTEEIKMLKS DNAVLNQRYL EALAMLDIKQ
260 270 280 290 300
QKMAQENMCC DKSGFAEASG LELAVLGACL CHGPGGNPCS CARMAASTRK
310 320 330 340 350
LLLQLKQELE ILQKSKEEAY VMADAFRIAF EQQLMRKNDQ ALQLTQMDKM
360 370 380 390 400
HKKATKWMNW KHLKEDGFPS PRSKKTFGQR LLGMLPSENS SKRMEDQDSP
410 420 430 440 450
QEVLKMLIDL LNDKEEALAH QRKVSYMLAR ALEDKDTASN ENKEKNPIKE
460 470 480 490 500
NFPFNNPWRK TSEFSVLGDP IHSSVCILNS VGCICSIQHS QIDPNYRTLK
510
RSHSLPSSII F
Length:511
Mass (Da):58,629
Last modified:November 25, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB6174A2DDA1CE2DA
GO
Isoform 2 (identifier: Q86Z20-2) [UniParc]FASTAAdd to basket
Also known as: Kenae-2

The sequence of this isoform differs from the canonical sequence as follows:
     1-125: Missing.

Note: No experimental confirmation available.
Show »
Length:386
Mass (Da):44,248
Checksum:i2A72F82BC64054C8
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8W912F8W912_HUMAN
Coiled-coil domain-containing prote...
CCDC125
312Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03250513V → M1 PublicationCorresponds to variant dbSNP:rs10471774Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0257811 – 125Missing in isoform 2. 1 PublicationAdd BLAST125

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB024691 mRNA Translation: BAC57450.1
AB024692 mRNA Translation: BAC57451.1
AC145132 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS4000.1 [Q86Z20-1]
CCDS75255.1 [Q86Z20-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001284626.1, NM_001297697.1 [Q86Z20-2]
NP_789786.2, NM_176816.4 [Q86Z20-1]
XP_005248515.1, XM_005248458.4 [Q86Z20-1]
XP_005248520.1, XM_005248463.3 [Q86Z20-2]
XP_011541557.1, XM_011543255.2 [Q86Z20-1]
XP_011541558.1, XM_011543256.2 [Q86Z20-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000396496; ENSP00000379754; ENSG00000183323 [Q86Z20-1]
ENST00000396499; ENSP00000379756; ENSG00000183323 [Q86Z20-1]
ENST00000511257; ENSP00000426795; ENSG00000183323 [Q86Z20-2]
ENST00000612469; ENSP00000484313; ENSG00000277868 [Q86Z20-2]
ENST00000619386; ENSP00000481190; ENSG00000277868 [Q86Z20-1]
ENST00000620431; ENSP00000479651; ENSG00000277868 [Q86Z20-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
202243

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:202243

UCSC genome browser

More...
UCSCi
uc003jvv.2 human [Q86Z20-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB024691 mRNA Translation: BAC57450.1
AB024692 mRNA Translation: BAC57451.1
AC145132 Genomic DNA No translation available.
CCDSiCCDS4000.1 [Q86Z20-1]
CCDS75255.1 [Q86Z20-2]
RefSeqiNP_001284626.1, NM_001297697.1 [Q86Z20-2]
NP_789786.2, NM_176816.4 [Q86Z20-1]
XP_005248515.1, XM_005248458.4 [Q86Z20-1]
XP_005248520.1, XM_005248463.3 [Q86Z20-2]
XP_011541557.1, XM_011543255.2 [Q86Z20-1]
XP_011541558.1, XM_011543256.2 [Q86Z20-1]

3D structure databases

SMRiQ86Z20
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ86Z20, 66 interactors
STRINGi9606.ENSP00000379754

PTM databases

iPTMnetiQ86Z20
PhosphoSitePlusiQ86Z20

Polymorphism and mutation databases

BioMutaiCCDC125
DMDMi215273947

Proteomic databases

jPOSTiQ86Z20
MassIVEiQ86Z20
MaxQBiQ86Z20
PaxDbiQ86Z20
PeptideAtlasiQ86Z20
PRIDEiQ86Z20
ProteomicsDBi70497 [Q86Z20-1]
70498 [Q86Z20-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
202243

Genome annotation databases

EnsembliENST00000396496; ENSP00000379754; ENSG00000183323 [Q86Z20-1]
ENST00000396499; ENSP00000379756; ENSG00000183323 [Q86Z20-1]
ENST00000511257; ENSP00000426795; ENSG00000183323 [Q86Z20-2]
ENST00000612469; ENSP00000484313; ENSG00000277868 [Q86Z20-2]
ENST00000619386; ENSP00000481190; ENSG00000277868 [Q86Z20-1]
ENST00000620431; ENSP00000479651; ENSG00000277868 [Q86Z20-1]
GeneIDi202243
KEGGihsa:202243
UCSCiuc003jvv.2 human [Q86Z20-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
202243
DisGeNETi202243

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CCDC125
HGNCiHGNC:28924 CCDC125
HPAiHPA041878
MIMi613781 gene
neXtProtiNX_Q86Z20
OpenTargetsiENSG00000183323
PharmGKBiPA147358306

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IKFY Eukaryota
ENOG410YHUF LUCA
GeneTreeiENSGT00440000039958
HOGENOMiHOG000063705
InParanoidiQ86Z20
OMAiEVQTWET
OrthoDBi1152075at2759
PhylomeDBiQ86Z20
TreeFamiTF332719

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CCDC125 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
202243
PharosiQ86Z20

Protein Ontology

More...
PROi
PR:Q86Z20

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000183323 Expressed in 147 organ(s), highest expression level in blood
ExpressionAtlasiQ86Z20 baseline and differential
GenevisibleiQ86Z20 HS

Family and domain databases

InterProiView protein in InterPro
IPR034608 CCDC125
PANTHERiPTHR28616 PTHR28616, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCC125_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86Z20
Secondary accession number(s): Q86Z19
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: November 25, 2008
Last modified: October 16, 2019
This is version 110 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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