UniProtKB - Q86YS7 (C2CD5_HUMAN)
Protein
C2 domain-containing protein 5
Gene
C2CD5
Organism
Homo sapiens (Human)
Status
Functioni
Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes. Binds phospholipid membranes in a calcium-dependent manner and is necessary for the optimal membrane fusion between SLC2A4/GLUT4 GSV and the PM.1 Publication
Cofactori
Ca2+PROSITE-ProRule annotationNote: Binds 3 Ca2+ ions per C2 domain.PROSITE-ProRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 19 | Calcium 1PROSITE-ProRule annotation | 1 | |
Metal bindingi | 19 | Calcium 2PROSITE-ProRule annotation | 1 | |
Metal bindingi | 26 | Calcium 1PROSITE-ProRule annotation | 1 | |
Metal bindingi | 76 | Calcium 1PROSITE-ProRule annotation | 1 | |
Metal bindingi | 76 | Calcium 2PROSITE-ProRule annotation | 1 | |
Metal bindingi | 78 | Calcium 1PROSITE-ProRule annotation | 1 | |
Metal bindingi | 78 | Calcium 2PROSITE-ProRule annotation | 1 | |
Metal bindingi | 78 | Calcium 3PROSITE-ProRule annotation | 1 | |
Metal bindingi | 81 | Calcium 3PROSITE-ProRule annotation | 1 | |
Metal bindingi | 84 | Calcium 2PROSITE-ProRule annotation | 1 | |
Metal bindingi | 84 | Calcium 3PROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Calcium bindingi | 13 – 27 | 1; low affinityAdd BLAST | 15 | |
Calcium bindingi | 75 – 86 | 2; high affinityAdd BLAST | 12 |
GO - Molecular functioni
- calcium-dependent phospholipid binding Source: UniProtKB
- calcium ion binding Source: UniProtKB
GO - Biological processi
- cellular response to insulin stimulus Source: UniProtKB
- insulin receptor signaling pathway via phosphatidylinositol 3-kinase Source: UniProtKB
- intracellular protein transmembrane transport Source: UniProtKB
- positive regulation of glucose import Source: Ensembl
- positive regulation of glucose transmembrane transport Source: UniProtKB
- positive regulation of protein targeting to membrane Source: UniProtKB
- positive regulation of vesicle fusion Source: UniProtKB
- protein localization to plasma membrane Source: GO_Central
- vesicle fusion Source: Ensembl
Keywordsi
Biological process | Protein transport, Transport |
Ligand | Calcium, Lipid-binding, Metal-binding |
Enzyme and pathway databases
PathwayCommonsi | Q86YS7 |
Reactomei | R-HSA-1445148, Translocation of SLC2A4 (GLUT4) to the plasma membrane |
Names & Taxonomyi
Protein namesi | Recommended name: C2 domain-containing protein 5Alternative name(s): C2 domain-containing phosphoprotein of 138 kDa |
Gene namesi | Name:C2CD5 Synonyms:CDP138, KIAA0528 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:29062, C2CD5 |
MIMi | 618044, gene |
neXtProti | NX_Q86YS7 |
VEuPathDBi | HostDB:ENSG00000111731.12 |
Subcellular locationi
Plasma membrane
- Cell membrane 1 Publication
Other locations
- Cytoplasmic vesicle membrane 1 Publication
- cell cortex 1 Publication
- ruffle 1 Publication
Note: Dynamically associated with GLUT4-containing glucose storage vesicles (GSV) and plasma membrane in response to insulin stimulation.
Cytoskeleton
- centriolar satellite Source: HPA
Cytosol
- cytosol Source: HPA
Plasma Membrane
- plasma membrane Source: UniProtKB
- ruffle membrane Source: UniProtKB
Other locations
- cell cortex Source: UniProtKB
- cytoplasmic vesicle membrane Source: UniProtKB
Keywords - Cellular componenti
Cell membrane, Cell projection, Cytoplasm, Cytoplasmic vesicle, MembranePathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 19 | D → A: Reduces calcium-binding, phospholipid membrane-binding and insulin-stimulated SLC2A4/GLUT4 translocation; when associated with A-26; A-76; A-78 and A-84. 1 Publication | 1 | |
Mutagenesisi | 26 | D → A: Reduces calcium-binding, phospholipid membrane-binding and insulin-stimulated SLC2A4/GLUT4 translocation; when associated with A-19; A-76; A-78 and A-84. 1 Publication | 1 | |
Mutagenesisi | 76 | D → A: Reduces calcium-binding, phospholipid membrane-binding and insulin-stimulated SLC2A4/GLUT4 translocation; when associated with A-19; A-26; A-78 and A-84. 1 Publication | 1 | |
Mutagenesisi | 78 | D → A: Reduces calcium-binding, phospholipid membrane-binding and insulin-stimulated SLC2A4/GLUT4 translocation; when associated with A-19; A-26; A-76 and A-84. 1 Publication | 1 | |
Mutagenesisi | 84 | D → A: Reduces calcium-binding, phospholipid membrane-binding and insulin-stimulated SLC2A4/GLUT4 translocation; when associated with A-19; A-26; A-76 and A-78. 1 Publication | 1 | |
Mutagenesisi | 197 | S → A: Inhibits insulin-stimulated AKT2-induced phosphorylation, SLC2A4/GLUT4 translocation to the cell surface and GSV-PM fusion. 1 Publication | 1 | |
Mutagenesisi | 200 | S → A: Does not inhibit insulin-stimulated SLC2A4/GLUT4 translocation. 1 Publication | 1 |
Organism-specific databases
DisGeNETi | 9847 |
OpenTargetsi | ENSG00000111731 |
PharmGKBi | PA143485515 |
Miscellaneous databases
Pharosi | Q86YS7, Tbio |
Genetic variation databases
BioMutai | C2CD5 |
DMDMi | 74750574 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000247450 | 1 – 1000 | C2 domain-containing protein 5Add BLAST | 1000 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 197 | Phosphoserine; by PKB/AKT21 Publication | 1 | |
Modified residuei | 200 | Phosphoserine1 Publication | 1 | |
Modified residuei | 260 | PhosphoserineCombined sources | 1 | |
Modified residuei | 293 | PhosphoserineCombined sources | 1 | |
Modified residuei | 295 | PhosphoserineCombined sources | 1 | |
Modified residuei | 304 | PhosphoserineBy similarity | 1 | |
Modified residuei | 305 | PhosphoserineCombined sources | 1 | |
Modified residuei | 306 | PhosphoserineBy similarity | 1 | |
Modified residuei | 317 | PhosphothreonineCombined sources | 1 | |
Modified residuei | 323 | PhosphoserineCombined sources | 1 | |
Modified residuei | 601 | PhosphothreonineCombined sources | 1 | |
Modified residuei | 643 | PhosphoserineCombined sources | 1 | |
Modified residuei | 657 | PhosphoserineBy similarity | 1 | |
Modified residuei | 659 | PhosphoserineCombined sources | 1 | |
Modified residuei | 661 | PhosphoserineBy similarity | 1 | |
Modified residuei | 662 | PhosphoserineCombined sources | 1 | |
Modified residuei | 666 | PhosphothreonineCombined sources | 1 | |
Modified residuei | 671 | PhosphoserineCombined sources | 1 | |
Modified residuei | 807 | PhosphothreonineCombined sources | 1 | |
Modified residuei | 817 | PhosphoserineBy similarity | 1 | |
Modified residuei | 852 | PhosphoserineCombined sources | 1 |
Post-translational modificationi
Phosphorylated on Ser-197 by active myristoylated kinase AKT2; insulin-stimulated phosphorylation by AKT2 regulates SLC2A4/GLUT4 translocation into the plasma membrane.1 Publication
Keywords - PTMi
PhosphoproteinProteomic databases
EPDi | Q86YS7 |
jPOSTi | Q86YS7 |
MassIVEi | Q86YS7 |
MaxQBi | Q86YS7 |
PaxDbi | Q86YS7 |
PeptideAtlasi | Q86YS7 |
PRIDEi | Q86YS7 |
ProteomicsDBi | 25908 26956 4964 70464 [Q86YS7-1] 70465 [Q86YS7-2] |
PTM databases
iPTMneti | Q86YS7 |
PhosphoSitePlusi | Q86YS7 |
Expressioni
Gene expression databases
Bgeei | ENSG00000111731, Expressed in secondary oocyte and 244 other tissues |
ExpressionAtlasi | Q86YS7, baseline and differential |
Genevisiblei | Q86YS7, HS |
Organism-specific databases
HPAi | ENSG00000111731, Low tissue specificity |
Interactioni
Binary interactionsi
Isoform 2 [Q86YS7-2]
With | #Exp. | IntAct |
---|---|---|
PICK1 [Q9NRD5] | 3 | EBI-12380221,EBI-79165 |
Protein-protein interaction databases
BioGRIDi | 115182, 47 interactors |
IntActi | Q86YS7, 32 interactors |
STRINGi | 9606.ENSP00000443204 |
Miscellaneous databases
RNActi | Q86YS7, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 109 | C2PROSITE-ProRule annotationAdd BLAST | 109 |
Domaini
The C2 domain binds to calcium and membrane lipids.
Phylogenomic databases
eggNOGi | KOG1031, Eukaryota |
GeneTreei | ENSGT00390000000212 |
HOGENOMi | CLU_003204_0_0_1 |
InParanoidi | Q86YS7 |
OMAi | DANKMKY |
OrthoDBi | 266134at2759 |
PhylomeDBi | Q86YS7 |
TreeFami | TF323431 |
Family and domain databases
CDDi | cd08688, C2_KIAA0528-like, 1 hit |
Gene3Di | 2.60.40.150, 1 hit |
InterProi | View protein in InterPro IPR037785, C2_C2CD5 IPR000008, C2_dom IPR035892, C2_domain_sf IPR038983, C2CD5 |
PANTHERi | PTHR37412, PTHR37412, 1 hit |
Pfami | View protein in Pfam PF00168, C2, 1 hit |
SMARTi | View protein in SMART SM00239, C2, 1 hit |
PROSITEi | View protein in PROSITE PS50004, C2, 1 hit |
s (5+)i Sequence
Sequence statusi: Complete.
This entry describes 5 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 5 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All
Isoform 1 (identifier: Q86YS7-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MPGKLKVKIV AGRHLPVMDR ASDLTDAFVE VKFGNTTFKT DVYLKSLNPQ
60 70 80 90 100
WNSEWFKFEV DDEDLQDEPL QITVLDHDTY SANDAIGKVY IDIDPLLYSE
110 120 130 140 150
AATVISGWFP IYDTIHGIRG EINVVVKVDL FNDLNRFRQS SCGVKFFCTT
160 170 180 190 200
SIPKCYRAVI IHGFVEELVV NEDPEYQWID RIRTPRASNE ARQRLISLMS
210 220 230 240 250
GELQRKIGLK VLEMRGNAVV GYLQCFDLEG ESGLVVRAIG TACTLDKLSS
260 270 280 290 300
PAAFLPACNS PSKEMKEIPF NEDPNPNTHS SGPSTPLKNQ TYSFSPSKSY
310 320 330 340 350
SRQSSSSDTD LSLTPKTGMG SGSAGKEGGP FKALLRQQTQ SALEQREFPF
360 370 380 390 400
FTLTAFPPGF LVHVGGVVSA RSVKLLDRIH NPDEPETRDA WWAEIRQEIK
410 420 430 440 450
SHAKALGCHA VVGYSESTSI CEEVCILSAS GTAAVLNPRF LQDGTVEGCL
460 470 480 490 500
EQRLEENLPT RCGFCHIPYD ELNMPFPAHL TYCYNCRKQK VPDVLFTTID
510 520 530 540 550
LPTDATVIGK GCLIQARLCR LKKKAQAEAN ATAISNLLPF MEYEVHTQLM
560 570 580 590 600
NKLKLKGMNA LFGLRIQITV GENMLMGLAS ATGVYLAALP TPGGIQIAGK
610 620 630 640 650
TPNDGSYEQH ISHMQKKIND TIAKNKELYE INPPEISEEI IGSPIPEPRQ
660 670 680 690 700
RSRLLRSQSE SSDEVTELDL SHGKKDAFVL EIDDTDAMED VHSLLTDVPP
710 720 730 740 750
PSGFYSCNTE IMPGINNWTS EIQMFTSVRV IRLSSLNLTN QALNKNFNDL
760 770 780 790 800
CENLLKSLYF KLRSMIPCCL CHVNFTVSLP EDELIQVTVT AVAITFDKNQ
810 820 830 840 850
ALQTTKTPVE KSLQRASTDN EELLQFPLEL CSDSLPSHPF PPAKAMTVEK
860 870 880 890 900
ASPVGDGNFR NRSAPPCANS TVGVVKMTPL SFIPGAKITK YLGIINMFFI
910 920 930 940 950
RETTSLREEG GVSGFLHAFI AEVFAMVRAH VAALGGNAVV SYIMKQCVFM
960 970 980 990 1000
ENPNKNQAQC LINVSGDAVV FVRESDLEVV SSQQPTTNCQ SSCTEGEVTT
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketH0YGU7 | H0YGU7_HUMAN | C2 domain-containing protein 5 | C2CD5 | 182 | Annotation score: | ||
H0YFE9 | H0YFE9_HUMAN | C2 domain-containing protein 5 | C2CD5 | 165 | Annotation score: | ||
H0YFC4 | H0YFC4_HUMAN | C2 domain-containing protein 5 | C2CD5 | 283 | Annotation score: |
Sequence cautioni
The sequence BAA25454 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence BAG58665 differs from that shown. Reason: Frameshift.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length | |
---|---|---|---|---|---|
Sequence conflicti | 997 | E → G in BAG58665 (PubMed:14702039).Curated | 1 | ||
Isoform 4 (identifier: Q86YS7-4) | |||||
Sequence conflicti | 895 | I → F in AAI43879 (PubMed:15489334).Curated | 1 | ||
Isoform 5 (identifier: Q86YS7-5) | |||||
Sequence conflicti | 895 | S → P in BAG58665 (PubMed:14702039).Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_028255 | 268 – 316 | IPFNE…SLTPK → SPLVHPPSHGCRSTHNSPIH TATGSRLTQNFSVSVPTLIY in isoform 2, isoform 4 and isoform 5. 2 PublicationsAdd BLAST | 49 | |
Alternative sequenceiVSP_055638 | 345 | Q → QRGGSPHRFCRR in isoform 4. 1 Publication | 1 | |
Alternative sequenceiVSP_055639 | 382 | P → PAFVGIMGNTRSYKLLDWNS FNS in isoform 5. 1 Publication | 1 | |
Alternative sequenceiVSP_028256 | 845 | A → EHLESASSNSGIPAAQRATS VDYSSFADRCSSWIELIKLK AQTIRRGSIKTT in isoform 2, isoform 3 and isoform 4. 2 Publications | 1 | |
Alternative sequenceiVSP_055640 | 845 | A → EHLESASSNSGIPAAQRDRC SSWIELIKLKAQTIRRGSIK TT in isoform 5. 1 Publication | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB011100 mRNA Translation: BAA25454.3 Different initiation. AY166851 mRNA Translation: AAO17290.1 AK295862 mRNA Translation: BAG58665.1 Frameshift. AK299353 mRNA Translation: BAG61349.1 AC053513 Genomic DNA No translation available. BC042498 mRNA Translation: AAH42498.2 BC053885 mRNA Translation: AAH53885.1 BC117143 mRNA Translation: AAI17144.1 BC143878 mRNA Translation: AAI43879.1 |
CCDSi | CCDS31758.1 [Q86YS7-1] CCDS66337.1 [Q86YS7-3] CCDS66338.1 [Q86YS7-2] CCDS66339.1 [Q86YS7-5] CCDS66340.1 [Q86YS7-4] |
PIRi | T00072 |
RefSeqi | NP_001273102.1, NM_001286173.1 [Q86YS7-4] NP_001273103.1, NM_001286174.1 [Q86YS7-3] NP_001273104.1, NM_001286175.1 [Q86YS7-5] NP_001273105.1, NM_001286176.1 [Q86YS7-3] NP_001273106.1, NM_001286177.1 [Q86YS7-2] NP_055617.1, NM_014802.2 [Q86YS7-1] |
Genome annotation databases
Ensembli | ENST00000333957; ENSP00000334229; ENSG00000111731 [Q86YS7-1] ENST00000396028; ENSP00000379345; ENSG00000111731 [Q86YS7-2] ENST00000446597; ENSP00000388756; ENSG00000111731 [Q86YS7-3] ENST00000536386; ENSP00000439392; ENSG00000111731 [Q86YS7-4] ENST00000542676; ENSP00000441951; ENSG00000111731 [Q86YS7-3] ENST00000545552; ENSP00000443204; ENSG00000111731 [Q86YS7-5] |
GeneIDi | 9847 |
KEGGi | hsa:9847 |
UCSCi | uc001rfq.5, human [Q86YS7-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB011100 mRNA Translation: BAA25454.3 Different initiation. AY166851 mRNA Translation: AAO17290.1 AK295862 mRNA Translation: BAG58665.1 Frameshift. AK299353 mRNA Translation: BAG61349.1 AC053513 Genomic DNA No translation available. BC042498 mRNA Translation: AAH42498.2 BC053885 mRNA Translation: AAH53885.1 BC117143 mRNA Translation: AAI17144.1 BC143878 mRNA Translation: AAI43879.1 |
CCDSi | CCDS31758.1 [Q86YS7-1] CCDS66337.1 [Q86YS7-3] CCDS66338.1 [Q86YS7-2] CCDS66339.1 [Q86YS7-5] CCDS66340.1 [Q86YS7-4] |
PIRi | T00072 |
RefSeqi | NP_001273102.1, NM_001286173.1 [Q86YS7-4] NP_001273103.1, NM_001286174.1 [Q86YS7-3] NP_001273104.1, NM_001286175.1 [Q86YS7-5] NP_001273105.1, NM_001286176.1 [Q86YS7-3] NP_001273106.1, NM_001286177.1 [Q86YS7-2] NP_055617.1, NM_014802.2 [Q86YS7-1] |
3D structure databases
SMRi | Q86YS7 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 115182, 47 interactors |
IntActi | Q86YS7, 32 interactors |
STRINGi | 9606.ENSP00000443204 |
PTM databases
iPTMneti | Q86YS7 |
PhosphoSitePlusi | Q86YS7 |
Genetic variation databases
BioMutai | C2CD5 |
DMDMi | 74750574 |
Proteomic databases
EPDi | Q86YS7 |
jPOSTi | Q86YS7 |
MassIVEi | Q86YS7 |
MaxQBi | Q86YS7 |
PaxDbi | Q86YS7 |
PeptideAtlasi | Q86YS7 |
PRIDEi | Q86YS7 |
ProteomicsDBi | 25908 26956 4964 70464 [Q86YS7-1] 70465 [Q86YS7-2] |
Protocols and materials databases
Antibodypediai | 24138, 46 antibodies |
Genome annotation databases
Ensembli | ENST00000333957; ENSP00000334229; ENSG00000111731 [Q86YS7-1] ENST00000396028; ENSP00000379345; ENSG00000111731 [Q86YS7-2] ENST00000446597; ENSP00000388756; ENSG00000111731 [Q86YS7-3] ENST00000536386; ENSP00000439392; ENSG00000111731 [Q86YS7-4] ENST00000542676; ENSP00000441951; ENSG00000111731 [Q86YS7-3] ENST00000545552; ENSP00000443204; ENSG00000111731 [Q86YS7-5] |
GeneIDi | 9847 |
KEGGi | hsa:9847 |
UCSCi | uc001rfq.5, human [Q86YS7-1] |
Organism-specific databases
CTDi | 9847 |
DisGeNETi | 9847 |
GeneCardsi | C2CD5 |
HGNCi | HGNC:29062, C2CD5 |
HPAi | ENSG00000111731, Low tissue specificity |
MIMi | 618044, gene |
neXtProti | NX_Q86YS7 |
OpenTargetsi | ENSG00000111731 |
PharmGKBi | PA143485515 |
VEuPathDBi | HostDB:ENSG00000111731.12 |
HUGEi | Search... |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG1031, Eukaryota |
GeneTreei | ENSGT00390000000212 |
HOGENOMi | CLU_003204_0_0_1 |
InParanoidi | Q86YS7 |
OMAi | DANKMKY |
OrthoDBi | 266134at2759 |
PhylomeDBi | Q86YS7 |
TreeFami | TF323431 |
Enzyme and pathway databases
PathwayCommonsi | Q86YS7 |
Reactomei | R-HSA-1445148, Translocation of SLC2A4 (GLUT4) to the plasma membrane |
Miscellaneous databases
BioGRID-ORCSi | 9847, 4 hits in 874 CRISPR screens |
ChiTaRSi | C2CD5, human |
GenomeRNAii | 9847 |
Pharosi | Q86YS7, Tbio |
PROi | PR:Q86YS7 |
RNActi | Q86YS7, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000111731, Expressed in secondary oocyte and 244 other tissues |
ExpressionAtlasi | Q86YS7, baseline and differential |
Genevisiblei | Q86YS7, HS |
Family and domain databases
CDDi | cd08688, C2_KIAA0528-like, 1 hit |
Gene3Di | 2.60.40.150, 1 hit |
InterProi | View protein in InterPro IPR037785, C2_C2CD5 IPR000008, C2_dom IPR035892, C2_domain_sf IPR038983, C2CD5 |
PANTHERi | PTHR37412, PTHR37412, 1 hit |
Pfami | View protein in Pfam PF00168, C2, 1 hit |
SMARTi | View protein in SMART SM00239, C2, 1 hit |
PROSITEi | View protein in PROSITE PS50004, C2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | C2CD5_HUMAN | |
Accessioni | Q86YS7Primary (citable) accession number: Q86YS7 Secondary accession number(s): B4DJ03 Q86SU3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 25, 2006 |
Last sequence update: | June 1, 2003 | |
Last modified: | February 10, 2021 | |
This is version 152 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 12
Human chromosome 12: entries, gene names and cross-references to MIM - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot