UniProtKB - Q86YN6 (PRGC2_HUMAN)
Peroxisome proliferator-activated receptor gamma coactivator 1-beta
PPARGC1B
Functioni
Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.
4 PublicationsGO - Molecular functioni
- AF-2 domain binding Source: UniProtKB
- estrogen receptor binding Source: UniProtKB
- nuclear receptor coactivator activity Source: UniProtKB
- RNA binding Source: UniProtKB
- transcription coregulator activity Source: UniProtKB
GO - Biological processi
- actin filament organization Source: Ensembl
- bone trabecula formation Source: Ensembl
- cellular response to reactive oxygen species Source: Ensembl
- intracellular estrogen receptor signaling pathway Source: UniProtKB
- mitochondrial transcription Source: Ensembl
- negative regulation of transcription, DNA-templated Source: Ensembl
- ossification Source: Ensembl
- positive regulation of alkaline phosphatase activity Source: Ensembl
- positive regulation of bone resorption Source: Ensembl
- positive regulation of cold-induced thermogenesis Source: YuBioLab
- positive regulation of DNA-binding transcription factor activity Source: GO_Central
- positive regulation of osteoclast differentiation Source: Ensembl
- positive regulation of phosphorylation Source: Ensembl
- positive regulation of transcription by RNA polymerase II Source: UniProtKB
- regulation of transcription, DNA-templated Source: UniProtKB
- response to cAMP Source: Ensembl
- response to glucocorticoid Source: Ensembl
Keywordsi
Molecular function | Activator, RNA-binding |
Biological process | Transcription, Transcription regulation |
Enzyme and pathway databases
PathwayCommonsi | Q86YN6 |
Reactomei | R-HSA-1989781, PPARA activates gene expression R-HSA-2151201, Transcriptional activation of mitochondrial biogenesis R-HSA-8939902, Regulation of RUNX2 expression and activity |
SignaLinki | Q86YN6 |
Names & Taxonomyi
Protein namesi | Recommended name: Peroxisome proliferator-activated receptor gamma coactivator 1-betaShort name: PGC-1-beta Short name: PPAR-gamma coactivator 1-beta Short name: PPARGC-1-beta Alternative name(s): PGC-1-related estrogen receptor alpha coactivator |
Gene namesi | Name:PPARGC1B Synonyms:PERC, PGC1, PGC1B, PPARGC1 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:30022, PPARGC1B |
MIMi | 608886, gene |
neXtProti | NX_Q86YN6 |
VEuPathDBi | HostDB:ENSG00000155846 |
Subcellular locationi
Nucleus
- Nucleus 1 Publication
Cytosol
- cytosol Source: HPA
Mitochondrion
- mitochondrion Source: GOC
Nucleus
- mediator complex Source: UniProtKB
- nucleoplasm Source: HPA
- nucleus Source: UniProtKB
Keywords - Cellular componenti
NucleusPathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 92 – 96 | LLAEL → AAAEA: Reduces DNA transcriptional activity. 1 Publication | 5 | |
Mutagenesisi | 155 – 160 | LLQKLL → AAQKAA: Reduces interaction and activation of ESR1. Loss of interaction and activation of ESR1; when associated with 343-AREAA-347. 1 Publication | 6 | |
Mutagenesisi | 343 – 347 | LRELL → AREAA: Reduces interaction and activation of ESR1. Loss of interaction and activation of ESR1; when associated with 155-AAQKAA-160. 1 Publication | 5 |
Organism-specific databases
DisGeNETi | 133522 |
OpenTargetsi | ENSG00000155846 |
PharmGKBi | PA134953410 |
Miscellaneous databases
Pharosi | Q86YN6, Tbio |
Chemistry databases
DrugBanki | DB01118, Amiodarone |
Genetic variation databases
BioMutai | PPARGC1B |
DMDMi | 116242724 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000240158 | 1 – 1023 | Peroxisome proliferator-activated receptor gamma coactivator 1-betaAdd BLAST | 1023 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 384 | PhosphoserineCombined sources | 1 | |
Modified residuei | 524 | PhosphoserineCombined sources | 1 | |
Modified residuei | 638 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
jPOSTi | Q86YN6 |
MassIVEi | Q86YN6 |
MaxQBi | Q86YN6 |
PaxDbi | Q86YN6 |
PeptideAtlasi | Q86YN6 |
PRIDEi | Q86YN6 |
ProteomicsDBi | 70440 [Q86YN6-1] 70441 [Q86YN6-2] 70442 [Q86YN6-3] 70443 [Q86YN6-4] 70444 [Q86YN6-5] 70445 [Q86YN6-6] |
PTM databases
iPTMneti | Q86YN6 |
PhosphoSitePlusi | Q86YN6 |
Expressioni
Tissue specificityi
Inductioni
Gene expression databases
Bgeei | ENSG00000155846, Expressed in quadriceps femoris and 186 other tissues |
ExpressionAtlasi | Q86YN6, baseline and differential |
Genevisiblei | Q86YN6, HS |
Organism-specific databases
HPAi | ENSG00000155846, Tissue enhanced (retina) |
Interactioni
Subunit structurei
Interacts with hepatocyte nuclear factor 4-alpha/HNF4A, Sterol regulatory binding transcription factor 1/SREBF1, PPAR-alpha/PPARA, thyroid hormone receptor beta/THRB and host cell factor/HCFC1.
Interacts with estrogen-related receptor gamma/ESRRG and alpha/ESRRA.
Interacts with PRDM16 (By similarity).
Interacts with estrogen receptor alpha/ESR1.
By similarity1 PublicationGO - Molecular functioni
- AF-2 domain binding Source: UniProtKB
- estrogen receptor binding Source: UniProtKB
Protein-protein interaction databases
BioGRIDi | 126361, 24 interactors |
IntActi | Q86YN6, 12 interactors |
STRINGi | 9606.ENSP00000312649 |
Miscellaneous databases
RNActi | Q86YN6, protein |
Structurei
Secondary structure
3D structure databases
SMRi | Q86YN6 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q86YN6 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 902 – 976 | RRMPROSITE-ProRule annotationAdd BLAST | 75 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 91 | Abolishes DNA transcriptional activity when missingAdd BLAST | 91 | |
Regioni | 122 – 148 | DisorderedSequence analysisAdd BLAST | 27 | |
Regioni | 165 – 210 | DisorderedSequence analysisAdd BLAST | 46 | |
Regioni | 237 – 278 | DisorderedSequence analysisAdd BLAST | 42 | |
Regioni | 302 – 331 | DisorderedSequence analysisAdd BLAST | 30 | |
Regioni | 369 – 463 | DisorderedSequence analysisAdd BLAST | 95 | |
Regioni | 520 – 567 | DisorderedSequence analysisAdd BLAST | 48 | |
Regioni | 601 – 623 | DisorderedSequence analysisAdd BLAST | 23 | |
Regioni | 636 – 683 | DisorderedSequence analysisAdd BLAST | 48 | |
Regioni | 717 – 758 | DisorderedSequence analysisAdd BLAST | 42 | |
Regioni | 779 – 867 | DisorderedSequence analysisAdd BLAST | 89 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 156 – 160 | LXXLL motif 1 | 5 | |
Motifi | 343 – 347 | LXXLL motif 2 | 5 | |
Motifi | 691 – 694 | HCFC1-binding-motif (HBM) | 4 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 131 – 145 | Pro residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 165 – 184 | Polar residuesSequence analysisAdd BLAST | 20 | |
Compositional biasi | 411 – 429 | Basic and acidic residuesSequence analysisAdd BLAST | 19 | |
Compositional biasi | 430 – 447 | Acidic residuesSequence analysisAdd BLAST | 18 | |
Compositional biasi | 653 – 667 | Basic and acidic residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 734 – 758 | Basic and acidic residuesSequence analysisAdd BLAST | 25 | |
Compositional biasi | 789 – 803 | Polar residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 804 – 826 | Acidic residuesSequence analysisAdd BLAST | 23 | |
Compositional biasi | 831 – 867 | Polar residuesSequence analysisAdd BLAST | 37 |
Domaini
Keywords - Domaini
RepeatPhylogenomic databases
eggNOGi | ENOG502QTA7, Eukaryota |
GeneTreei | ENSGT00950000183137 |
HOGENOMi | CLU_014202_0_0_1 |
InParanoidi | Q86YN6 |
OMAi | CHEKRAC |
OrthoDBi | 94418at2759 |
PhylomeDBi | Q86YN6 |
TreeFami | TF343068 |
Family and domain databases
CDDi | cd12356, RRM_PPARGC1B, 1 hit |
Gene3Di | 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR012677, Nucleotide-bd_a/b_plait_sf IPR034605, PGC-1 IPR034621, PGC-1beta IPR034177, PPARGC1B_RRM IPR035979, RBD_domain_sf IPR000504, RRM_dom |
PANTHERi | PTHR15528, PTHR15528, 1 hit PTHR15528:SF12, PTHR15528:SF12, 1 hit |
Pfami | View protein in Pfam PF00076, RRM_1, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 1 hit |
SUPFAMi | SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50102, RRM, 1 hit |
s (6+)i Sequence
Sequence statusi: Complete.
This entry describes 6 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 6 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MAGNDCGALL DEELSSFFLN YLADTQGGGS GEEQLYADFP ELDLSQLDAS
60 70 80 90 100
DFDSATCFGE LQWCPENSET EPNQYSPDDS ELFQIDSENE ALLAELTKTL
110 120 130 140 150
DDIPEDDVGL AAFPALDGGD ALSCTSASPA PSSAPPSPAP EKPSAPAPEV
160 170 180 190 200
DELSLLQKLL LATSYPTSSS DTQKEGTAWR QAGLRSKSQR PCVKADSTQD
210 220 230 240 250
KKAPMMQSQS RSCTELHKHL TSAQCCLQDR GLQPPCLQSP RLPAKEDKEP
260 270 280 290 300
GEDCPSPQPA PASPRDSLAL GRADPGAPVS QEDMQAMVQL IRYMHTYCLP
310 320 330 340 350
QRKLPPQTPE PLPKACSNPS QQVRSRPWSR HHSKASWAEF SILRELLAQD
360 370 380 390 400
VLCDVSKPYR LATPVYASLT PRSRPRPPKD SQASPGRPSS VEEVRIAASP
410 420 430 440 450
KSTGPRPSLR PLRLEVKREV RRPARLQQQE EEDEEEEEEE EEEEKEEEEE
460 470 480 490 500
WGRKRPGRGL PWTKLGRKLE SSVCPVRRSR RLNPELGPWL TFADEPLVPS
510 520 530 540 550
EPQGALPSLC LAPKAYDVER ELGSPTDEDS GQDQQLLRGP QIPALESPCE
560 570 580 590 600
SGCGDMDEDP SCPQLPPRDS PRCLMLALSQ SDPTFGKKSF EQTLTVELCG
610 620 630 640 650
TAGLTPPTTP PYKPTEEDPF KPDIKHSLGK EIALSLPSPE GLSLKATPGA
660 670 680 690 700
AHKLPKKHPE RSELLSHLRH ATAQPASQAG QKRPFSCSFG DHDYCQVLRP
710 720 730 740 750
EGVLQRKVLR SWEPSGVHLE DWPQQGAPWA EAQAPGREED RSCDAGAPPK
760 770 780 790 800
DSTLLRDHEI RASLTKHFGL LETALEEEDL ASCKSPEYDT VFEDSSSSSG
810 820 830 840 850
ESSFLPEEEE EEGEEEEEDD EEEDSGVSPT CSDHCPYQSP PSKANRQLCS
860 870 880 890 900
RSRSSSGSSP CHSWSPATRR NFRCESRGPC SDRTPSIRHA RKRREKAIGE
910 920 930 940 950
GRVVYIQNLS SDMSSRELKR RFEVFGEIEE CEVLTRNRRG EKYGFITYRC
960 970 980 990 1000
SEHAALSLTK GAALRKRNEP SFQLSYGGLR HFCWPRYTDY DSNSEEALPA
1010 1020
SGKSKYEAMD FDSLLKEAQQ SLH
The sequence of this isoform differs from the canonical sequence as follows:
156-194: Missing.
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketH0Y713 | H0Y713_HUMAN | Peroxisome proliferator-activated r... | PPARGC1B | 748 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 558 | E → G in BAC04541 (PubMed:14702039).Curated | 1 |
Polymorphismi
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_026698 | 203 | A → P1 PublicationCorresponds to variant dbSNP:rs7732671EnsemblClinVar. | 1 | |
Natural variantiVAR_026699 | 265 | R → Q1 PublicationCorresponds to variant dbSNP:rs45520937Ensembl. | 1 | |
Natural variantiVAR_026700 | 279 | V → I1 PublicationCorresponds to variant dbSNP:rs17572019Ensembl. | 1 | |
Natural variantiVAR_026701 | 292 | R → S2 PublicationsCorresponds to variant dbSNP:rs11959820Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_019299 | 1 – 26 | MAGND…LADTQ → MGVYK in isoform 2 and isoform 4. 1 PublicationAdd BLAST | 26 | |
Alternative sequenceiVSP_043374 | 1 – 26 | MAGND…LADTQ → M in isoform 6. 1 PublicationAdd BLAST | 26 | |
Alternative sequenceiVSP_019300 | 156 – 194 | Missing in isoform 5 and isoform 6. 2 PublicationsAdd BLAST | 39 | |
Alternative sequenceiVSP_019301 | 991 – 1023 | DSNSE…QQSLH → GKPLKPSHSLVRLKAWEAVP SLNKTQS in isoform 3 and isoform 4. 1 PublicationAdd BLAST | 33 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF468496 mRNA Translation: AAL78633.1 AF468497 mRNA Translation: AAL78634.1 AY188947 mRNA Translation: AAO40022.1 AY188948 mRNA Translation: AAO40023.1 AY188949 mRNA Translation: AAO40024.1 AY188950 mRNA Translation: AAO40025.1 AK095391 mRNA Translation: BAC04541.1 AK123614 mRNA Translation: BAG53922.1 AC008545 Genomic DNA No translation available. AC022100 Genomic DNA No translation available. CH471062 Genomic DNA Translation: EAW61759.1 BC132971 mRNA Translation: AAI32972.1 BC132973 mRNA Translation: AAI32974.1 |
CCDSi | CCDS4298.1 [Q86YN6-1] CCDS54933.1 [Q86YN6-5] CCDS54934.1 [Q86YN6-6] |
RefSeqi | NP_001166169.1, NM_001172698.1 [Q86YN6-5] NP_001166170.1, NM_001172699.1 [Q86YN6-6] NP_573570.3, NM_133263.3 [Q86YN6-1] XP_005268429.1, XM_005268372.4 [Q86YN6-2] |
Genome annotation databases
Ensembli | ENST00000309241; ENSP00000312649; ENSG00000155846 ENST00000360453; ENSP00000353638; ENSG00000155846 [Q86YN6-5] ENST00000394320; ENSP00000377855; ENSG00000155846 [Q86YN6-3] ENST00000403750; ENSP00000384403; ENSG00000155846 [Q86YN6-6] |
GeneIDi | 133522 |
KEGGi | hsa:133522 |
MANE-Selecti | ENST00000309241.10; ENSP00000312649.5; NM_133263.4; NP_573570.3 |
UCSCi | uc003lrb.3, human [Q86YN6-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF468496 mRNA Translation: AAL78633.1 AF468497 mRNA Translation: AAL78634.1 AY188947 mRNA Translation: AAO40022.1 AY188948 mRNA Translation: AAO40023.1 AY188949 mRNA Translation: AAO40024.1 AY188950 mRNA Translation: AAO40025.1 AK095391 mRNA Translation: BAC04541.1 AK123614 mRNA Translation: BAG53922.1 AC008545 Genomic DNA No translation available. AC022100 Genomic DNA No translation available. CH471062 Genomic DNA Translation: EAW61759.1 BC132971 mRNA Translation: AAI32972.1 BC132973 mRNA Translation: AAI32974.1 |
CCDSi | CCDS4298.1 [Q86YN6-1] CCDS54933.1 [Q86YN6-5] CCDS54934.1 [Q86YN6-6] |
RefSeqi | NP_001166169.1, NM_001172698.1 [Q86YN6-5] NP_001166170.1, NM_001172699.1 [Q86YN6-6] NP_573570.3, NM_133263.3 [Q86YN6-1] XP_005268429.1, XM_005268372.4 [Q86YN6-2] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3SP6 | X-ray | 2.21 | B | 153-163 | [»] | |
6D0Y | X-ray | 2.68 | B | 994-1023 | [»] | |
SMRi | Q86YN6 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 126361, 24 interactors |
IntActi | Q86YN6, 12 interactors |
STRINGi | 9606.ENSP00000312649 |
Chemistry databases
DrugBanki | DB01118, Amiodarone |
PTM databases
iPTMneti | Q86YN6 |
PhosphoSitePlusi | Q86YN6 |
Genetic variation databases
BioMutai | PPARGC1B |
DMDMi | 116242724 |
Proteomic databases
jPOSTi | Q86YN6 |
MassIVEi | Q86YN6 |
MaxQBi | Q86YN6 |
PaxDbi | Q86YN6 |
PeptideAtlasi | Q86YN6 |
PRIDEi | Q86YN6 |
ProteomicsDBi | 70440 [Q86YN6-1] 70441 [Q86YN6-2] 70442 [Q86YN6-3] 70443 [Q86YN6-4] 70444 [Q86YN6-5] 70445 [Q86YN6-6] |
Protocols and materials databases
Antibodypediai | 27863, 113 antibodies from 29 providers |
DNASUi | 133522 |
Genome annotation databases
Ensembli | ENST00000309241; ENSP00000312649; ENSG00000155846 ENST00000360453; ENSP00000353638; ENSG00000155846 [Q86YN6-5] ENST00000394320; ENSP00000377855; ENSG00000155846 [Q86YN6-3] ENST00000403750; ENSP00000384403; ENSG00000155846 [Q86YN6-6] |
GeneIDi | 133522 |
KEGGi | hsa:133522 |
MANE-Selecti | ENST00000309241.10; ENSP00000312649.5; NM_133263.4; NP_573570.3 |
UCSCi | uc003lrb.3, human [Q86YN6-1] |
Organism-specific databases
CTDi | 133522 |
DisGeNETi | 133522 |
GeneCardsi | PPARGC1B |
HGNCi | HGNC:30022, PPARGC1B |
HPAi | ENSG00000155846, Tissue enhanced (retina) |
MIMi | 608886, gene |
neXtProti | NX_Q86YN6 |
OpenTargetsi | ENSG00000155846 |
PharmGKBi | PA134953410 |
VEuPathDBi | HostDB:ENSG00000155846 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502QTA7, Eukaryota |
GeneTreei | ENSGT00950000183137 |
HOGENOMi | CLU_014202_0_0_1 |
InParanoidi | Q86YN6 |
OMAi | CHEKRAC |
OrthoDBi | 94418at2759 |
PhylomeDBi | Q86YN6 |
TreeFami | TF343068 |
Enzyme and pathway databases
PathwayCommonsi | Q86YN6 |
Reactomei | R-HSA-1989781, PPARA activates gene expression R-HSA-2151201, Transcriptional activation of mitochondrial biogenesis R-HSA-8939902, Regulation of RUNX2 expression and activity |
SignaLinki | Q86YN6 |
Miscellaneous databases
BioGRID-ORCSi | 133522, 328 hits in 1049 CRISPR screens |
ChiTaRSi | PPARGC1B, human |
EvolutionaryTracei | Q86YN6 |
GeneWikii | PPARGC1B |
GenomeRNAii | 133522 |
Pharosi | Q86YN6, Tbio |
PROi | PR:Q86YN6 |
RNActi | Q86YN6, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000155846, Expressed in quadriceps femoris and 186 other tissues |
ExpressionAtlasi | Q86YN6, baseline and differential |
Genevisiblei | Q86YN6, HS |
Family and domain databases
CDDi | cd12356, RRM_PPARGC1B, 1 hit |
Gene3Di | 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR012677, Nucleotide-bd_a/b_plait_sf IPR034605, PGC-1 IPR034621, PGC-1beta IPR034177, PPARGC1B_RRM IPR035979, RBD_domain_sf IPR000504, RRM_dom |
PANTHERi | PTHR15528, PTHR15528, 1 hit PTHR15528:SF12, PTHR15528:SF12, 1 hit |
Pfami | View protein in Pfam PF00076, RRM_1, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 1 hit |
SUPFAMi | SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50102, RRM, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | PRGC2_HUMAN | |
Accessioni | Q86YN6Primary (citable) accession number: Q86YN6 Secondary accession number(s): A2RUM8 Q8TDE5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 13, 2006 |
Last sequence update: | October 17, 2006 | |
Last modified: | February 23, 2022 | |
This is version 162 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Human chromosome 5
Human chromosome 5: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references