UniProtKB - Q86YD7 (F90A1_HUMAN)
Protein
Protein FAM90A1
Gene
FAM90A1
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Protein FAM90A1 |
Gene namesi | Name:FAM90A1 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000171847.10 |
HGNCi | HGNC:25526, FAM90A1 |
MIMi | 613041, gene |
neXtProti | NX_Q86YD7 |
Pathology & Biotechi
Organism-specific databases
OpenTargetsi | ENSG00000171847 |
PharmGKBi | PA142671796 |
Miscellaneous databases
Pharosi | Q86YD7, Tdark |
Polymorphism and mutation databases
BioMutai | FAM90A1 |
DMDMi | 269849691 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000299592 | 1 – 464 | Protein FAM90A1Add BLAST | 464 |
Proteomic databases
PaxDbi | Q86YD7 |
PeptideAtlasi | Q86YD7 |
PRIDEi | Q86YD7 |
ProteomicsDBi | 70405 |
PTM databases
iPTMneti | Q86YD7 |
PhosphoSitePlusi | Q86YD7 |
Expressioni
Gene expression databases
Bgeei | ENSG00000171847, Expressed in right hemisphere of cerebellum and 102 other tissues |
ExpressionAtlasi | Q86YD7, baseline and differential |
Genevisiblei | Q86YD7, HS |
Organism-specific databases
HPAi | ENSG00000171847, Tissue enhanced (brain) |
Interactioni
Binary interactionsi
Q86YD7
Protein-protein interaction databases
BioGRIDi | 120442, 176 interactors |
IntActi | Q86YD7, 173 interactors |
MINTi | Q86YD7 |
STRINGi | 9606.ENSP00000445418 |
Miscellaneous databases
RNActi | Q86YD7, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the FAM90 family.Curated
Phylogenomic databases
eggNOGi | ENOG502RU1C, Eukaryota |
GeneTreei | ENSGT00910000144208 |
HOGENOMi | CLU_047915_0_1_1 |
InParanoidi | Q86YD7 |
OMAi | EKSEAPC |
OrthoDBi | 791998at2759 |
PhylomeDBi | Q86YD7 |
TreeFami | TF338572 |
Family and domain databases
InterProi | View protein in InterPro IPR039213, FAM90 IPR041670, Znf-CCHC_6 |
PANTHERi | PTHR16035, PTHR16035, 1 hit |
Pfami | View protein in Pfam PF15288, zf-CCHC_6, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q86YD7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MMARRDPKPG AKRLVRAQTL QKQRRAPVGP RAPPPDEEDP RLKCKNCEAF
60 70 80 90 100
GHTARSTRCP MKCWKAALVP PNFGEKEGKE NLKPWKPQVE ANPGPLNKDK
110 120 130 140 150
GEKEERPRPQ DPQRKALLHI FSRKPPEKPL PNQKGSTESS DYLRVASGPM
160 170 180 190 200
PVHTTSKRPR VDPVLSDRSA TEMSDRGSVL ASLSPLRKAS LSSSSSLGPK
210 220 230 240 250
ERQTGAAADI PQTAVRHQGP EPLLVVKPTH SSPAGGCREV PQAASKTHGL
260 270 280 290 300
LQAVSPQAQD KRPAVTSQPC PPAATHSLGL GSNLSFGPGA KRSAPAPIQA
310 320 330 340 350
CLNFPKKPRL GPFQIPESAI QGGELGAPEN LQPPPAATEL GPRTSPQTGT
360 370 380 390 400
RTPAQVLSGD RQPPHSRPCL PTAQACTMSH HPAASHDGAQ PLRVLFRRLE
410 420 430 440 450
NGRWSSSLLT APSFHSPEKP GAFLAQSPHV SEKSEGPCVR VPPSVLYEDL
460
QVPSSSEDSD SDLE
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketF5H7S5 | F5H7S5_HUMAN | Protein FAM90A1 | FAM90A1 | 14 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 254 – 255 | VS → AR in AAH42608 (PubMed:15489334).Curated | 2 | |
Sequence conflicti | 344 | T → TV in BAA91593 (PubMed:14702039).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_060293 | 123 | R → G2 PublicationsCorresponds to variant dbSNP:rs9738115Ensembl. | 1 | |
Natural variantiVAR_057778 | 234 | A → E1 PublicationCorresponds to variant dbSNP:rs9668582EnsemblClinVar. | 1 | |
Natural variantiVAR_060294 | 334 | P → L1 PublicationCorresponds to variant dbSNP:rs17855656Ensembl. | 1 | |
Natural variantiVAR_060154 | 343 | R → S. Corresponds to variant dbSNP:rs9668475Ensembl. | 1 | |
Natural variantiVAR_060295 | 348 | T → I3 PublicationsCorresponds to variant dbSNP:rs9668474Ensembl. | 1 | |
Natural variantiVAR_060155 | 410 | T → A. Corresponds to variant dbSNP:rs11044098Ensembl. | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK001270 mRNA Translation: BAA91593.1 AC092111 Genomic DNA No translation available. CH471116 Genomic DNA Translation: EAW88629.1 CH471116 Genomic DNA Translation: EAW88630.1 BC042608 mRNA Translation: AAH42608.1 |
CCDSi | CCDS31738.1 |
RefSeqi | NP_001306911.1, NM_001319982.1 NP_060558.3, NM_018088.3 XP_011519021.1, XM_011520719.1 XP_016875036.1, XM_017019547.1 |
Genome annotation databases
Ensembli | ENST00000307435; ENSP00000307798; ENSG00000171847 ENST00000538603; ENSP00000445418; ENSG00000171847 |
GeneIDi | 55138 |
KEGGi | hsa:55138 |
UCSCi | uc001quh.3, human |
Keywords - Coding sequence diversityi
PolymorphismSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK001270 mRNA Translation: BAA91593.1 AC092111 Genomic DNA No translation available. CH471116 Genomic DNA Translation: EAW88629.1 CH471116 Genomic DNA Translation: EAW88630.1 BC042608 mRNA Translation: AAH42608.1 |
CCDSi | CCDS31738.1 |
RefSeqi | NP_001306911.1, NM_001319982.1 NP_060558.3, NM_018088.3 XP_011519021.1, XM_011520719.1 XP_016875036.1, XM_017019547.1 |
3D structure databases
SMRi | Q86YD7 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 120442, 176 interactors |
IntActi | Q86YD7, 173 interactors |
MINTi | Q86YD7 |
STRINGi | 9606.ENSP00000445418 |
PTM databases
iPTMneti | Q86YD7 |
PhosphoSitePlusi | Q86YD7 |
Polymorphism and mutation databases
BioMutai | FAM90A1 |
DMDMi | 269849691 |
Proteomic databases
PaxDbi | Q86YD7 |
PeptideAtlasi | Q86YD7 |
PRIDEi | Q86YD7 |
ProteomicsDBi | 70405 |
Protocols and materials databases
Antibodypediai | 23050, 34 antibodies |
DNASUi | 55138 |
Genome annotation databases
Ensembli | ENST00000307435; ENSP00000307798; ENSG00000171847 ENST00000538603; ENSP00000445418; ENSG00000171847 |
GeneIDi | 55138 |
KEGGi | hsa:55138 |
UCSCi | uc001quh.3, human |
Organism-specific databases
CTDi | 55138 |
EuPathDBi | HostDB:ENSG00000171847.10 |
GeneCardsi | FAM90A1 |
HGNCi | HGNC:25526, FAM90A1 |
HPAi | ENSG00000171847, Tissue enhanced (brain) |
MIMi | 613041, gene |
neXtProti | NX_Q86YD7 |
OpenTargetsi | ENSG00000171847 |
PharmGKBi | PA142671796 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502RU1C, Eukaryota |
GeneTreei | ENSGT00910000144208 |
HOGENOMi | CLU_047915_0_1_1 |
InParanoidi | Q86YD7 |
OMAi | EKSEAPC |
OrthoDBi | 791998at2759 |
PhylomeDBi | Q86YD7 |
TreeFami | TF338572 |
Enzyme and pathway databases
PathwayCommonsi | Q86YD7 |
Miscellaneous databases
BioGRID-ORCSi | 55138, 5 hits in 843 CRISPR screens |
ChiTaRSi | FAM90A1, human |
GenomeRNAii | 55138 |
Pharosi | Q86YD7, Tdark |
PROi | PR:Q86YD7 |
RNActi | Q86YD7, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000171847, Expressed in right hemisphere of cerebellum and 102 other tissues |
ExpressionAtlasi | Q86YD7, baseline and differential |
Genevisiblei | Q86YD7, HS |
Family and domain databases
InterProi | View protein in InterPro IPR039213, FAM90 IPR041670, Znf-CCHC_6 |
PANTHERi | PTHR16035, PTHR16035, 1 hit |
Pfami | View protein in Pfam PF15288, zf-CCHC_6, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F90A1_HUMAN | |
Accessioni | Q86YD7Primary (citable) accession number: Q86YD7 Secondary accession number(s): D3DUU9, Q9NVZ6 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 11, 2007 |
Last sequence update: | November 24, 2009 | |
Last modified: | December 2, 2020 | |
This is version 121 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families - Human chromosome 12
Human chromosome 12: entries, gene names and cross-references to MIM - Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations