Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - Q86Y33 (CD20B_HUMAN)

Entry version 144 (10 Feb 2021)
Sequence version 3 (10 Aug 2010)
Previous versions | rss
Add a publicationFeedback
Protein

Cell division cycle protein 20 homolog B

Gene

CDC20B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q86Y33

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q86Y33

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cell division cycle protein 20 homolog B
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CDC20B
ORF Names:G6VTS76519
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:24222, CDC20B

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q86Y33

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000164287.12

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		166979

Open Targets

More...OpenTargetsi		ENSG00000164287

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA145149217

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q86Y33, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		CDC20B

Domain mapping of disease mutations (DMDM)

More...DMDMi		302393826

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003391101 – 519Cell division cycle protein 20 homolog BAdd BLAST519

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q86Y33

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q86Y33

PeptideAtlas

More...PeptideAtlasi		Q86Y33

PRoteomics IDEntifications database

More...PRIDEi		Q86Y33

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		70361 [Q86Y33-1]
70362 [Q86Y33-2]
70363 [Q86Y33-3]
70364 [Q86Y33-4]
70365 [Q86Y33-5]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q86Y33

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q86Y33

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000164287, Expressed in secondary oocyte and 38 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q86Y33, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000164287, Group enriched (endometrium, fallopian tube, kidney, lung, testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		127940, 28 interactors

Protein interaction database and analysis system

More...IntActi		Q86Y33, 29 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000370781

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q86Y33, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q86Y33

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati229 – 266WD 1Add BLAST38
Repeati271 – 310WD 2Add BLAST40
Repeati311 – 341WD 3Add BLAST31
Repeati353 – 392WD 4Add BLAST40
Repeati399 – 441WD 5Add BLAST43
Repeati443 – 484WD 6Add BLAST42
Repeati487 – 519WD 7Add BLAST33

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the WD repeat CDC20/Fizzy family.Curated

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0305, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00950000183104

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_014831_6_2_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q86Y33

Identification of Orthologs from Complete Genome Data

More...OMAi		TACVWNC

Database of Orthologous Groups

More...OrthoDBi		1220675at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q86Y33

TreeFam database of animal gene trees

More...TreeFami		TF337979

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.130.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR033010, Cdc20/Fizzy
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR019775, WD40_repeat_CS
IPR017986, WD40_repeat_dom
IPR036322, WD40_repeat_dom_sf

The PANTHER Classification System

More...PANTHERi		PTHR19918, PTHR19918, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00400, WD40, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00320, WD40, 5 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50978, SSF50978, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00678, WD_REPEATS_1, 1 hit
PS50082, WD_REPEATS_2, 3 hits
PS50294, WD_REPEATS_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (5)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 5 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q86Y33-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEWKLERTAP RRVRTEEEML WESIMRVLSK DLKQKRSQDS ANVLDSVNAT 
        60         70         80         90        100
YSDFKSNFAK RLSAEVPVAS SPITTRWQQS QTRALSSDSF GEEQSTTYLP 
       110        120        130        140        150
EASGSVLKTP PEKETLTLGS RKEQLKTPSK GISETSNSAL HFCKAPHAMD 
       160        170        180        190        200
RDWKESVASK GQKCLKQLFV TQNVVQQANG KMQLCEQSEC VWKGCKDGVR 
       210        220        230        240        250
DESFHLKSSG DINDSILQPE VKIHITGLRN DYYLNILDWS FQNLVAIALG 
       260        270        280        290        300
SAVYIWNGEN HNGIENIDLS LTCNYISSVS WIKEGTCLAV GTSEGEVQLW 
       310        320        330        340        350
DVVTKKRLRN MLGHLSVVGA LSWNHFILSS GSRLGRVYHH DVRVAQHHVG 
       360        370        380        390        400
TLRHKQAVCA LKWSPDGRLL SSGCSDGLLT IWPHDPGASA QGQPLKVITQ 
       410        420        430        440        450
STAVKAMDWC PWQSGVLAIG GGMKDGRLHI LDINAGKSIQ TPSTNSQICS 
       460        470        480        490        500
LIWLPKTKEI ATGQGTPKND VTVWTCPTVS RSGGFFGHRG RVLHLSLSPD 
       510 
QTRVFSAAAD GTASVWNCY
Length:519
Mass (Da):57,335
Last modified:August 10, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2D40A57A4363A349
GO
Isoform 2 (identifier: Q86Y33-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     483-486: Missing.

Show »
Length:515
Mass (Da):56,927
Checksum:iC9DC5381A7EA8C6D
GO
Isoform 3 (identifier: Q86Y33-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     406-447: Missing.

Show »
Length:477
Mass (Da):52,898
Checksum:i156E243FF6FF2BBE
GO
Isoform 4 (identifier: Q86Y33-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     330-372: SGSRLGRVYH...WSPDGRLLSS → RLEFSGVISA...WGVFIITMFG
     373-519: Missing.

Show »
Length:372
Mass (Da):41,849
Checksum:i6C26758297E77056
GO
Isoform 5 (identifier: Q86Y33-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     22-42: Missing.
     194-213: GCKDGVRDESFHLKSSGDIN → DHFSGSMKKRFEQEDVGGKD
     214-519: Missing.

Show »
Length:192
Mass (Da):21,697
Checksum:i0AF24C360751729F
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB97393 differs from that shown. Reason: Erroneous initiation.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0438608T → P. Corresponds to variant dbSNP:rs173042Ensembl.1
Natural variantiVAR_04386117E → K. Corresponds to variant dbSNP:rs423074Ensembl.1
Natural variantiVAR_04386297T → S. Corresponds to variant dbSNP:rs34132993Ensembl.1
Natural variantiVAR_043863121R → C4 PublicationsCorresponds to variant dbSNP:rs1021580Ensembl.1
Natural variantiVAR_043864496S → A4 PublicationsCorresponds to variant dbSNP:rs3104230Ensembl.1
Natural variantiVAR_043865503R → W2 PublicationsCorresponds to variant dbSNP:rs444527Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_03408922 – 42Missing in isoform 5. 1 PublicationAdd BLAST21
Alternative sequenceiVSP_034090194 – 213GCKDG…SGDIN → DHFSGSMKKRFEQEDVGGKD in isoform 5. 1 PublicationAdd BLAST20
Alternative sequenceiVSP_034091214 – 519Missing in isoform 5. 1 PublicationAdd BLAST306
Alternative sequenceiVSP_034092330 – 372SGSRL…RLLSS → RLEFSGVISAHCNLHLPSSW DYRRPPPCLVGQDWGVFIIT MFG in isoform 4. 1 PublicationAdd BLAST43
Alternative sequenceiVSP_034093373 – 519Missing in isoform 4. 1 PublicationAdd BLAST147
Alternative sequenceiVSP_034094406 – 447Missing in isoform 3. 1 PublicationAdd BLAST42
Alternative sequenceiVSP_034095483 – 486Missing in isoform 2. 2 Publications4

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB077043 mRNA Translation: BAC67701.1
AB077044 mRNA Translation: BAB97393.1 Different initiation.
AB081750 mRNA Translation: BAC67702.1
AB086378 mRNA Translation: BAC67705.1
AK095246 mRNA Translation: BAC04508.1
AC091977 Genomic DNA No translation available.
CH471123 Genomic DNA Translation: EAW54901.1
BC037547 mRNA Translation: AAH37547.1
BC136572 mRNA Translation: AAI36573.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS3966.1 [Q86Y33-2]
CCDS47207.1 [Q86Y33-3]
CCDS54852.1 [Q86Y33-1]

NCBI Reference Sequences

More...RefSeqi		NP_001139206.2, NM_001145734.2 [Q86Y33-3]
NP_001163873.1, NM_001170402.1 [Q86Y33-1]
NP_689836.2, NM_152623.2 [Q86Y33-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000296733; ENSP00000296733; ENSG00000164287 [Q86Y33-2]
ENST00000322374; ENSP00000315720; ENSG00000164287 [Q86Y33-3]
ENST00000381375; ENSP00000370781; ENSG00000164287 [Q86Y33-1]
ENST00000507931; ENSP00000423919; ENSG00000164287 [Q86Y33-5]
ENST00000513180; ENSP00000426776; ENSG00000164287 [Q86Y33-4]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		166979

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:166979

UCSC genome browser

More...UCSCi		uc003jpn.3, human [Q86Y33-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB077043 mRNA Translation: BAC67701.1
AB077044 mRNA Translation: BAB97393.1 Different initiation.
AB081750 mRNA Translation: BAC67702.1
AB086378 mRNA Translation: BAC67705.1
AK095246 mRNA Translation: BAC04508.1
AC091977 Genomic DNA No translation available.
CH471123 Genomic DNA Translation: EAW54901.1
BC037547 mRNA Translation: AAH37547.1
BC136572 mRNA Translation: AAI36573.1
CCDSiCCDS3966.1 [Q86Y33-2]
CCDS47207.1 [Q86Y33-3]
CCDS54852.1 [Q86Y33-1]
RefSeqiNP_001139206.2, NM_001145734.2 [Q86Y33-3]
NP_001163873.1, NM_001170402.1 [Q86Y33-1]
NP_689836.2, NM_152623.2 [Q86Y33-2]

3D structure databases

SMRiQ86Y33
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi127940, 28 interactors
IntActiQ86Y33, 29 interactors
STRINGi9606.ENSP00000370781

PTM databases

iPTMnetiQ86Y33
PhosphoSitePlusiQ86Y33

Genetic variation databases

BioMutaiCDC20B
DMDMi302393826

Proteomic databases

jPOSTiQ86Y33
PaxDbiQ86Y33
PeptideAtlasiQ86Y33
PRIDEiQ86Y33
ProteomicsDBi70361 [Q86Y33-1]
70362 [Q86Y33-2]
70363 [Q86Y33-3]
70364 [Q86Y33-4]
70365 [Q86Y33-5]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		23375, 136 antibodies

Genome annotation databases

EnsembliENST00000296733; ENSP00000296733; ENSG00000164287 [Q86Y33-2]
ENST00000322374; ENSP00000315720; ENSG00000164287 [Q86Y33-3]
ENST00000381375; ENSP00000370781; ENSG00000164287 [Q86Y33-1]
ENST00000507931; ENSP00000423919; ENSG00000164287 [Q86Y33-5]
ENST00000513180; ENSP00000426776; ENSG00000164287 [Q86Y33-4]
GeneIDi166979
KEGGihsa:166979
UCSCiuc003jpn.3, human [Q86Y33-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		166979
DisGeNETi166979

GeneCards: human genes, protein and diseases

More...GeneCardsi		CDC20B
HGNCiHGNC:24222, CDC20B
HPAiENSG00000164287, Group enriched (endometrium, fallopian tube, kidney, lung, testis)
neXtProtiNX_Q86Y33
OpenTargetsiENSG00000164287
PharmGKBiPA145149217
VEuPathDBiHostDB:ENSG00000164287.12

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG0305, Eukaryota
GeneTreeiENSGT00950000183104
HOGENOMiCLU_014831_6_2_1
InParanoidiQ86Y33
OMAiTACVWNC
OrthoDBi1220675at2759
PhylomeDBiQ86Y33
TreeFamiTF337979

Enzyme and pathway databases

PathwayCommonsiQ86Y33
SignaLinkiQ86Y33

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		166979, 4 hits in 867 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		CDC20B, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		166979
PharosiQ86Y33, Tdark

Protein Ontology

More...PROi		PR:Q86Y33
RNActiQ86Y33, protein

Gene expression databases

BgeeiENSG00000164287, Expressed in secondary oocyte and 38 other tissues
GenevisibleiQ86Y33, HS

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR033010, Cdc20/Fizzy
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR019775, WD40_repeat_CS
IPR017986, WD40_repeat_dom
IPR036322, WD40_repeat_dom_sf
PANTHERiPTHR19918, PTHR19918, 1 hit
PfamiView protein in Pfam
PF00400, WD40, 2 hits
SMARTiView protein in SMART
SM00320, WD40, 5 hits
SUPFAMiSSF50978, SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678, WD_REPEATS_1, 1 hit
PS50082, WD_REPEATS_2, 3 hits
PS50294, WD_REPEATS_REGION, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCD20B_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86Y33
Secondary accession number(s): B7WNV8
, B9EGL8, C9J6X8, C9JHE9, C9JKL5, Q86Y31, Q86Y32, Q8IUZ8, Q8N1S1, Q8NG56
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: August 10, 2010
Last modified: February 10, 2021
This is version 144 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human entries with genetic variants
    List of human entries with genetic variants
  2. Human variants curated from literature reports
    Index of human variants curated from literature reports
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again