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Entry version 135 (12 Aug 2020)
Sequence version 1 (01 Jun 2003)
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Protein

Spermatogenesis-associated serine-rich protein 2

Gene

SPATS2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q86XZ4

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Spermatogenesis-associated serine-rich protein 2
Alternative name(s):
Serine-rich spermatocytes and round spermatid 59 kDa protein
p59scr
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SPATS2
Synonyms:SCR59, SPATA10
ORF Names:Nbla00526
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000123352.17

Human Gene Nomenclature Database

More...
HGNCi
HGNC:18650, SPATS2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
611667, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q86XZ4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
65244

Open Targets

More...
OpenTargetsi
ENSG00000123352

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134871579

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q86XZ4, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SPATS2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74750549

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003076971 – 545Spermatogenesis-associated serine-rich protein 2Add BLAST545

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei143PhosphoserineBy similarity1
Modified residuei146PhosphoserineCombined sources1
Modified residuei148PhosphoserineBy similarity1
Modified residuei520PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q86XZ4

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q86XZ4

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q86XZ4

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q86XZ4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q86XZ4

PeptideAtlas

More...
PeptideAtlasi
Q86XZ4

PRoteomics IDEntifications database

More...
PRIDEi
Q86XZ4

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
70343

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q86XZ4

MetOSite database of methionine sulfoxide sites

More...
MetOSitei
Q86XZ4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q86XZ4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000123352, Expressed in testis and 226 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q86XZ4, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q86XZ4, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000123352, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
122410, 31 interactors

Protein interaction database and analysis system

More...
IntActi
Q86XZ4, 28 interactors

Molecular INTeraction database

More...
MINTi
Q86XZ4

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000448228

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q86XZ4, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q86XZ4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi86 – 97Poly-LysAdd BLAST12
Compositional biasi364 – 414Ser-richAdd BLAST51

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SPATS2 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QY9Y, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000001138

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_037089_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q86XZ4

Identification of Orthologs from Complete Genome Data

More...
OMAi
IFDVQSN

Database of Orthologous Groups

More...
OrthoDBi
1523681at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q86XZ4

TreeFam database of animal gene trees

More...
TreeFami
TF320553

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009816, DUF1387
IPR009060, UBA-like_sf

The PANTHER Classification System

More...
PANTHERi
PTHR15623, PTHR15623, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07139, DUF1387, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46934, SSF46934, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 12 potential isoforms that are computationally mapped.Show allAlign All

Q86XZ4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSRKQNQKDS SGFIFDLQSN TVLAQGGAFE NMKEKINAVR AIVPNKSNNE
60 70 80 90 100
IILVLQHFDN CVDKTVQAFM EGSASEVLKE WTVTGKKKNK KKKNKPKPAA
110 120 130 140 150
EPSNGIPDSS KSVSIQEEQS APSSEKGGMN GYHVNGAIND TESVDSLSEG
160 170 180 190 200
LETLSIDARE LEDPESAMLD TLDRTGSMLQ NGVSDFETKS LTMHSIHNSQ
210 220 230 240 250
QPRNAAKSLS RPTTETQFSN MGMEDVPLAT SKKLSSNIEK SVKDLQRCTV
260 270 280 290 300
SLARYRVVVK EEMDASIKKM KQAFAELESC LMDREVALLA EMDKVKAEAM
310 320 330 340 350
EILLSRQKKA ELLKKMTHVA VQMSEQQLVE LRADIKHFVS ERKYDEDLGR
360 370 380 390 400
VARFTCDVET LKKSIDSFGQ VSHPKNSYST RSRCSSVTSV SLSSPSDASA
410 420 430 440 450
ASSSTCASPP SLTSANKKNF APGETPAAIA NSSGQPYQPL REVLPGNRRG
460 470 480 490 500
GQGYRPQGQK SNDPMNQGRH DSMGRYRNSS WYSSGSRYQS APSQAPGNTI
510 520 530 540
ERGQTHSAGT NGTGVSMEPS PPTPSFKKGL PQRKPRTSQT EAVNS
Length:545
Mass (Da):59,545
Last modified:June 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE203EA5BA3FDB0BF
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 12 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8VS10F8VS10_HUMAN
Spermatogenesis-associated serine-r...
SPATS2
295Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8VXB3F8VXB3_HUMAN
Spermatogenesis-associated serine-r...
SPATS2
98Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8VRH4F8VRH4_HUMAN
Spermatogenesis-associated serine-r...
SPATS2
74Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8VVF0F8VVF0_HUMAN
Spermatogenesis-associated serine-r...
SPATS2
75Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8VXP9F8VXP9_HUMAN
Spermatogenesis-associated serine-r...
SPATS2
67Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8VZS5F8VZS5_HUMAN
Spermatogenesis-associated serine-r...
SPATS2
66Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8W1X1F8W1X1_HUMAN
Spermatogenesis-associated serine-r...
SPATS2
36Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8VX46F8VX46_HUMAN
Spermatogenesis-associated serine-r...
SPATS2
33Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8VX66F8VX66_HUMAN
Spermatogenesis-associated serine-r...
SPATS2
63Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8W128F8W128_HUMAN
Spermatogenesis-associated serine-r...
SPATS2
34Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB14448 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAB14958 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti393S → N in BAB14958 (PubMed:14702039).Curated1
Sequence conflicti514G → R in BAB14460 (PubMed:14702039).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB075515 mRNA Translation: BAE45760.1
AK023179 mRNA Translation: BAB14448.1 Different initiation.
AK023202 mRNA Translation: BAB14460.1
AK024678 mRNA Translation: BAB14958.1 Different initiation.
AK292334 mRNA Translation: BAF85023.1
CH471111 Genomic DNA Translation: EAW58068.1
BC048299 mRNA Translation: AAH48299.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS31794.1

NCBI Reference Sequences

More...
RefSeqi
NP_001280214.1, NM_001293285.1
NP_001280215.1, NM_001293286.1
NP_075559.2, NM_023071.3
XP_011536992.1, XM_011538690.2
XP_011536993.1, XM_011538691.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000321898; ENSP00000326841; ENSG00000123352
ENST00000552918; ENSP00000447947; ENSG00000123352
ENST00000553127; ENSP00000448228; ENSG00000123352

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
65244

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:65244

UCSC genome browser

More...
UCSCi
uc001rud.3, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB075515 mRNA Translation: BAE45760.1
AK023179 mRNA Translation: BAB14448.1 Different initiation.
AK023202 mRNA Translation: BAB14460.1
AK024678 mRNA Translation: BAB14958.1 Different initiation.
AK292334 mRNA Translation: BAF85023.1
CH471111 Genomic DNA Translation: EAW58068.1
BC048299 mRNA Translation: AAH48299.1
CCDSiCCDS31794.1
RefSeqiNP_001280214.1, NM_001293285.1
NP_001280215.1, NM_001293286.1
NP_075559.2, NM_023071.3
XP_011536992.1, XM_011538690.2
XP_011536993.1, XM_011538691.2

3D structure databases

SMRiQ86XZ4
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi122410, 31 interactors
IntActiQ86XZ4, 28 interactors
MINTiQ86XZ4
STRINGi9606.ENSP00000448228

PTM databases

iPTMnetiQ86XZ4
MetOSiteiQ86XZ4
PhosphoSitePlusiQ86XZ4

Polymorphism and mutation databases

BioMutaiSPATS2
DMDMi74750549

Proteomic databases

EPDiQ86XZ4
jPOSTiQ86XZ4
MassIVEiQ86XZ4
MaxQBiQ86XZ4
PaxDbiQ86XZ4
PeptideAtlasiQ86XZ4
PRIDEiQ86XZ4
ProteomicsDBi70343

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
48974, 38 antibodies

Genome annotation databases

EnsembliENST00000321898; ENSP00000326841; ENSG00000123352
ENST00000552918; ENSP00000447947; ENSG00000123352
ENST00000553127; ENSP00000448228; ENSG00000123352
GeneIDi65244
KEGGihsa:65244
UCSCiuc001rud.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
65244
DisGeNETi65244
EuPathDBiHostDB:ENSG00000123352.17

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SPATS2
HGNCiHGNC:18650, SPATS2
HPAiENSG00000123352, Low tissue specificity
MIMi611667, gene
neXtProtiNX_Q86XZ4
OpenTargetsiENSG00000123352
PharmGKBiPA134871579

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502QY9Y, Eukaryota
GeneTreeiENSGT00390000001138
HOGENOMiCLU_037089_0_0_1
InParanoidiQ86XZ4
OMAiIFDVQSN
OrthoDBi1523681at2759
PhylomeDBiQ86XZ4
TreeFamiTF320553

Enzyme and pathway databases

PathwayCommonsiQ86XZ4

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
65244, 12 hits in 870 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
SPATS2, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
65244
PharosiQ86XZ4, Tdark

Protein Ontology

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PROi
PR:Q86XZ4
RNActiQ86XZ4, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000123352, Expressed in testis and 226 other tissues
ExpressionAtlasiQ86XZ4, baseline and differential
GenevisibleiQ86XZ4, HS

Family and domain databases

InterProiView protein in InterPro
IPR009816, DUF1387
IPR009060, UBA-like_sf
PANTHERiPTHR15623, PTHR15623, 1 hit
PfamiView protein in Pfam
PF07139, DUF1387, 1 hit
SUPFAMiSSF46934, SSF46934, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSPAS2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86XZ4
Secondary accession number(s): A8K8G9
, Q9H7D4, Q9H8Y7, Q9H8Z8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: June 1, 2003
Last modified: August 12, 2020
This is version 135 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
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