UniProtKB - Q86XP1 (DGKH_HUMAN)
Diacylglycerol kinase eta
DGKH
Functioni
Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:12810723, PubMed:23949095).
Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable) (PubMed:12810723, PubMed:23949095).
Plays a key role in promoting cell growth (PubMed:19710016).
Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF (PubMed:19710016).
Regulates the recruitment of RAF1 and BRAF from cytoplasm to membranes and their heterodimerization (PubMed:19710016).
Curated3 PublicationsCatalytic activityi
- EC:2.7.1.1071 PublicationThis reaction proceeds in the forward1 Publication direction.
- 1,2-di-(9Z-octadecenoyl)-sn-glycerol + ATP = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H+2 PublicationsThis reaction proceeds in the forward1 Publication direction.
: glycerolipid metabolism Pathwayi
This protein is involved in the pathway glycerolipid metabolism, which is part of Lipid metabolism.1 PublicationView all proteins of this organism that are known to be involved in the pathway glycerolipid metabolism and in Lipid metabolism.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 175 – 225 | Phorbol-ester/DAG-type 1PROSITE-ProRule annotationAdd BLAST | 51 | |
Zinc fingeri | 247 – 298 | Phorbol-ester/DAG-type 2PROSITE-ProRule annotationAdd BLAST | 52 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- diacylglycerol kinase activity Source: BHF-UCL
- identical protein binding Source: UniProtKB
- kinase binding Source: UniProtKB
- metal ion binding Source: UniProtKB-KW
- NAD+ kinase activity Source: InterPro
- SAM domain binding Source: UniProtKB
GO - Biological processi
- diacylglycerol metabolic process Source: UniProtKB
- intracellular signal transduction Source: GO_Central
- lipid phosphorylation Source: UniProtKB
- negative regulation of catalytic activity Source: UniProtKB
- phosphatidic acid biosynthetic process Source: UniProtKB
- phosphatidic acid metabolic process Source: BHF-UCL
- platelet activation Source: Reactome
- protein kinase C-activating G protein-coupled receptor signaling pathway Source: UniProtKB
Keywordsi
Molecular function | Kinase, Transferase |
Biological process | Lipid metabolism |
Ligand | ATP-binding, Metal-binding, Nucleotide-binding, Zinc |
Enzyme and pathway databases
BRENDAi | 2.7.1.107, 2681 |
PathwayCommonsi | Q86XP1 |
Reactomei | R-HSA-114508, Effects of PIP2 hydrolysis |
SignaLinki | Q86XP1 |
UniPathwayi | UPA00230 |
Chemistry databases
SwissLipidsi | SLP:000000928 [Q86XP1-2] |
Names & Taxonomyi
Protein namesi | Recommended name: Diacylglycerol kinase etaCurated (EC:2.7.1.1072 Publications)Short name: DAG kinase eta Alternative name(s): Diglyceride kinase eta Short name: DGK-eta |
Gene namesi | Name:DGKHImported |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:2854, DGKH |
MIMi | 604071, gene |
neXtProti | NX_Q86XP1 |
VEuPathDBi | HostDB:ENSG00000102780 |
Subcellular locationi
Plasma membrane
- Cell membrane 2 Publications
Cytoplasm and Cytosol
- Cytoplasm 2 Publications
Note: Translocated from the cytoplasm to endosomes in response to stress stimuli (PubMed:12810723). Isoform 2 is rapidly relocated back to the cytoplasm upon removal of stress stimuli, whereas isoform 1 exhibits sustained endosomal association (PubMed:12810723). Translocates from the cytoplasm to the cell membrane in the presence of active GTP-bound form of HRAS (PubMed:19710016).
Cytoskeleton
- actin cytoskeleton Source: UniProtKB
Endosome
- endosome Source: UniProtKB
Plasma Membrane
- plasma membrane Source: HPA
Other locations
- cytoplasm Source: UniProtKB
- intracellular membrane-bounded organelle Source: HPA
- protein-containing complex Source: UniProtKB
Keywords - Cellular componenti
Cell membrane, Cytoplasm, MembranePathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 1151 | W → G: Loss of homoligomerization and heterooligomerization but not diacylglycerol kinase activity. 1 Publication | 1 |
Organism-specific databases
DisGeNETi | 160851 |
OpenTargetsi | ENSG00000102780 |
PharmGKBi | PA27315 |
Miscellaneous databases
Pharosi | Q86XP1, Tbio |
Chemistry databases
ChEMBLi | CHEMBL4105940 |
DrugBanki | DB14001, alpha-Tocopherol succinate |
Genetic variation databases
BioMutai | DGKH |
DMDMi | 74762463 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000239367 | 1 – 1220 | Diacylglycerol kinase etaAdd BLAST | 1220 |
Post-translational modificationi
Keywords - PTMi
PhosphoproteinProteomic databases
EPDi | Q86XP1 |
jPOSTi | Q86XP1 |
MassIVEi | Q86XP1 |
MaxQBi | Q86XP1 |
PaxDbi | Q86XP1 |
PeptideAtlasi | Q86XP1 |
PRIDEi | Q86XP1 |
ProteomicsDBi | 5568 70309 [Q86XP1-1] 70310 [Q86XP1-2] 70311 [Q86XP1-3] |
PTM databases
iPTMneti | Q86XP1 |
PhosphoSitePlusi | Q86XP1 |
Expressioni
Tissue specificityi
Inductioni
Gene expression databases
Bgeei | ENSG00000102780, Expressed in dorsal root ganglion and 207 other tissues |
ExpressionAtlasi | Q86XP1, baseline and differential |
Genevisiblei | Q86XP1, HS |
Organism-specific databases
HPAi | ENSG00000102780, Tissue enhanced (brain) |
Interactioni
Subunit structurei
Interacts with RAF1 and BRAF.
1 PublicationGO - Molecular functioni
- identical protein binding Source: UniProtKB
- kinase binding Source: UniProtKB
- SAM domain binding Source: UniProtKB
Protein-protein interaction databases
BioGRIDi | 127768, 34 interactors |
IntActi | Q86XP1, 7 interactors |
STRINGi | 9606.ENSP00000337572 |
Miscellaneous databases
RNActi | Q86XP1, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 65 – 158 | PHPROSITE-ProRule annotationAdd BLAST | 94 | |
Domaini | 328 – 463 | DAGKcPROSITE-ProRule annotationAdd BLAST | 136 | |
Domaini | 1151 – 1214 | SAMPROSITE-ProRule annotationAdd BLAST | 64 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 60 | DisorderedSequence analysisAdd BLAST | 60 | |
Regioni | 581 – 617 | DisorderedSequence analysisAdd BLAST | 37 | |
Regioni | 636 – 705 | DisorderedSequence analysisAdd BLAST | 70 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 1218 – 1220 | PDZ-binding | 3 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 589 – 603 | Basic and acidic residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 658 – 677 | Basic and acidic residuesSequence analysisAdd BLAST | 20 |
Domaini
Sequence similaritiesi
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 175 – 225 | Phorbol-ester/DAG-type 1PROSITE-ProRule annotationAdd BLAST | 51 | |
Zinc fingeri | 247 – 298 | Phorbol-ester/DAG-type 2PROSITE-ProRule annotationAdd BLAST | 52 |
Keywords - Domaini
Repeat, Zinc-fingerPhylogenomic databases
eggNOGi | KOG1170, Eukaryota |
GeneTreei | ENSGT00940000158106 |
HOGENOMi | CLU_001799_3_0_1 |
InParanoidi | Q86XP1 |
OMAi | FERAHTR |
OrthoDBi | 43384at2759 |
PhylomeDBi | Q86XP1 |
TreeFami | TF313104 |
Family and domain databases
CDDi | cd00029, C1, 2 hits |
Gene3Di | 1.10.150.50, 1 hit 2.30.29.30, 1 hit 3.40.50.10330, 1 hit |
InterProi | View protein in InterPro IPR017438, ATP-NAD_kinase_N IPR046349, C1-like_sf IPR037607, DGK IPR000756, Diacylglycerol_kin_accessory IPR001206, Diacylglycerol_kinase_cat_dom IPR016064, NAD/diacylglycerol_kinase_sf IPR002219, PE/DAG-bd IPR011993, PH-like_dom_sf IPR001849, PH_domain IPR001660, SAM IPR013761, SAM/pointed_sf |
PANTHERi | PTHR11255, PTHR11255, 1 hit |
Pfami | View protein in Pfam PF00130, C1_1, 2 hits PF00609, DAGK_acc, 1 hit PF00781, DAGK_cat, 1 hit PF00169, PH, 1 hit PF07647, SAM_2, 1 hit |
SMARTi | View protein in SMART SM00109, C1, 2 hits SM00045, DAGKa, 1 hit SM00046, DAGKc, 1 hit SM00233, PH, 1 hit SM00454, SAM, 1 hit |
SUPFAMi | SSF111331, SSF111331, 1 hit SSF47769, SSF47769, 1 hit SSF57889, SSF57889, 2 hits |
PROSITEi | View protein in PROSITE PS50146, DAGK, 1 hit PS50003, PH_DOMAIN, 1 hit PS50105, SAM_DOMAIN, 1 hit PS00479, ZF_DAG_PE_1, 2 hits PS50081, ZF_DAG_PE_2, 2 hits |
s (4+)i Sequence
Sequence statusi: Complete.
This entry describes 4 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 4 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MAGAGGQHHP PGAAGGAAAG AGAAVTSAAA SAGPGEDSSD SEAEQEGPQK
60 70 80 90 100
LIRKVSTSGQ IRTKTSIKEG QLLKQTSSFQ RWKKRYFKLR GRTLYYAKDS
110 120 130 140 150
KSLIFDEVDL SDASVAEAST KNANNSFTII TPFRRLMLCA ENRKEMEDWI
160 170 180 190 200
SSLKSVQTRE PYEVAQFNVE HFSGMHNWYA CSHARPTFCN VCRESLSGVT
210 220 230 240 250
SHGLSCEVCK FKAHKRCAVR ATNNCKWTTL ASIGKDIIED EDGVAMPHQW
260 270 280 290 300
LEGNLPVSAK CAVCDKTCGS VLRLQDWKCL WCKTMVHTAC KDLYHPICPL
310 320 330 340 350
GQCKVSIIPP IALNSTDSDG FCRATFSFCV SPLLVFVNSK SGDNQGVKFL
360 370 380 390 400
RRFKQLLNPA QVFDLMNGGP HLGLRLFQKF DNFRILVCGG DGSVGWVLSE
410 420 430 440 450
IDKLNLNKQC QLGVLPLGTG NDLARVLGWG GSYDDDTQLP QILEKLERAS
460 470 480 490 500
TKMLDRWSIM TYELKLPPKA SLLPGPPEAS EEFYMTIYED SVATHLTKIL
510 520 530 540 550
NSDEHAVVIS SAKTLCETVK DFVAKVEKTY DKTLENAVVA DAVASKCSVL
560 570 580 590 600
NEKLEQLLQA LHTDSQAAPV LPGLSPLIVE EDAVESSSEE SLGESKEQLG
610 620 630 640 650
DDVTKPSSQK AVKPREIMLR ANSLKKAVRQ VIEEAGKVMD DPTVHPCEPA
660 670 680 690 700
NQSSDYDSTE TDESKEEAKD DGAKESITVK TAPRSPDARA SYGHSQTDSV
710 720 730 740 750
PGPAVAASKE NLPVLNTRII CPGLRAGLAA SIAGSSIINK MLLANIDPFG
760 770 780 790 800
ATPFIDPDLD SVDGYSEKCV MNNYFGIGLD AKISLEFNNK REEHPEKCRS
810 820 830 840 850
RTKNLMWYGV LGTRELLQRS YKNLEQRVQL ECDGQYIPLP SLQGIAVLNI
860 870 880 890 900
PSYAGGTNFW GGTKEDDIFA APSFDDKILE VVAIFDSMQM AVSRVIKLQH
910 920 930 940 950
HRIAQCRTVK ITIFGDEGVP VQVDGEAWVQ PPGIIKIVHK NRAQMLTRDR
960 970 980 990 1000
AFESTLKSWE DKQKCDSGKP VLRTHLYIHH AIDLATEEVS QMQLCSQAAE
1010 1020 1030 1040 1050
ELITRICDAA TIHCLLEQEL AHAVNACSHA LNKANPRCPE SLTRDTATEI
1060 1070 1080 1090 1100
AINVKALYNE TESLLVGRVP LQLESPHEER VSNALHSVEV ELQKLTEIPW
1110 1120 1130 1140 1150
LYYILHPNED EEPPMDCTKR NNRSTVFRIV PKFKKEKVQK QKTSSQPVQK
1160 1170 1180 1190 1200
WGTEEVAAWL DLLNLGEYKD IFIRHDIRGA ELLHLERRDL KDLGIPKVGH
1210 1220
VKRILQGIKE LGRSTPQSEV
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A0D9SFR6 | A0A0D9SFR6_HUMAN | Diacylglycerol kinase | DGKH | 1,028 | Annotation score: | ||
A0A0D9SF65 | A0A0D9SF65_HUMAN | Diacylglycerol kinase eta | DGKH | 89 | Annotation score: | ||
A0A087WZ02 | A0A087WZ02_HUMAN | Diacylglycerol kinase eta | DGKH | 62 | Annotation score: |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 677 | I → M in BAC05280 (PubMed:14702039).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_033867 | 1201 | V → A. Corresponds to variant dbSNP:rs17646069Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_019183 | 1 – 136 | Missing in isoform 3 and isoform 4. 2 PublicationsAdd BLAST | 136 | |
Alternative sequenceiVSP_019185 | 1148 – 1220 | VQKWG…PQSEV → GSGDTESGSCEANSPGN in isoform 2. 2 PublicationsAdd BLAST | 73 | |
Alternative sequenceiVSP_019186 | 1191 | K → KNTVGEKRDTKENGKHM in isoform 3. 1 Publication | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB078967 mRNA Translation: BAC66960.1 AB078968 mRNA Translation: BAC66961.1 AK302727 mRNA Translation: BAG63946.1 AL136527 Genomic DNA No translation available. AL139328 Genomic DNA No translation available. AL157932 Genomic DNA No translation available. BC043292 mRNA Translation: AAH43292.1 AL833883 mRNA Translation: CAD38739.1 AK098302 mRNA Translation: BAC05280.1 Different initiation. |
CCDSi | CCDS55898.1 [Q86XP1-3] CCDS55899.1 [Q86XP1-5] CCDS9381.1 [Q86XP1-1] CCDS9382.1 [Q86XP1-2] |
RefSeqi | NP_001191433.1, NM_001204504.2 [Q86XP1-2] NP_001191434.1, NM_001204505.2 [Q86XP1-3] NP_001191435.1, NM_001204506.2 [Q86XP1-5] NP_001284358.1, NM_001297429.1 NP_690874.2, NM_152910.5 [Q86XP1-2] NP_821077.1, NM_178009.4 [Q86XP1-1] |
Genome annotation databases
Ensembli | ENST00000261491.9; ENSP00000261491.4; ENSG00000102780.17 [Q86XP1-2] ENST00000337343.9; ENSP00000337572.4; ENSG00000102780.17 ENST00000379274.6; ENSP00000368576.3; ENSG00000102780.17 [Q86XP1-2] ENST00000536612.3; ENSP00000445114.2; ENSG00000102780.17 [Q86XP1-3] ENST00000628433.2; ENSP00000485809.1; ENSG00000102780.17 [Q86XP1-5] |
GeneIDi | 160851 |
KEGGi | hsa:160851 |
MANE-Selecti | ENST00000337343.9; ENSP00000337572.4; NM_178009.5; NP_821077.1 |
UCSCi | uc001uyl.3, human [Q86XP1-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB078967 mRNA Translation: BAC66960.1 AB078968 mRNA Translation: BAC66961.1 AK302727 mRNA Translation: BAG63946.1 AL136527 Genomic DNA No translation available. AL139328 Genomic DNA No translation available. AL157932 Genomic DNA No translation available. BC043292 mRNA Translation: AAH43292.1 AL833883 mRNA Translation: CAD38739.1 AK098302 mRNA Translation: BAC05280.1 Different initiation. |
CCDSi | CCDS55898.1 [Q86XP1-3] CCDS55899.1 [Q86XP1-5] CCDS9381.1 [Q86XP1-1] CCDS9382.1 [Q86XP1-2] |
RefSeqi | NP_001191433.1, NM_001204504.2 [Q86XP1-2] NP_001191434.1, NM_001204505.2 [Q86XP1-3] NP_001191435.1, NM_001204506.2 [Q86XP1-5] NP_001284358.1, NM_001297429.1 NP_690874.2, NM_152910.5 [Q86XP1-2] NP_821077.1, NM_178009.4 [Q86XP1-1] |
3D structure databases
AlphaFoldDBi | Q86XP1 |
SMRi | Q86XP1 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 127768, 34 interactors |
IntActi | Q86XP1, 7 interactors |
STRINGi | 9606.ENSP00000337572 |
Chemistry databases
ChEMBLi | CHEMBL4105940 |
DrugBanki | DB14001, alpha-Tocopherol succinate |
SwissLipidsi | SLP:000000928 [Q86XP1-2] |
PTM databases
iPTMneti | Q86XP1 |
PhosphoSitePlusi | Q86XP1 |
Genetic variation databases
BioMutai | DGKH |
DMDMi | 74762463 |
Proteomic databases
EPDi | Q86XP1 |
jPOSTi | Q86XP1 |
MassIVEi | Q86XP1 |
MaxQBi | Q86XP1 |
PaxDbi | Q86XP1 |
PeptideAtlasi | Q86XP1 |
PRIDEi | Q86XP1 |
ProteomicsDBi | 5568 70309 [Q86XP1-1] 70310 [Q86XP1-2] 70311 [Q86XP1-3] |
Protocols and materials databases
Antibodypediai | 23454, 128 antibodies from 26 providers |
DNASUi | 160851 |
Genome annotation databases
Ensembli | ENST00000261491.9; ENSP00000261491.4; ENSG00000102780.17 [Q86XP1-2] ENST00000337343.9; ENSP00000337572.4; ENSG00000102780.17 ENST00000379274.6; ENSP00000368576.3; ENSG00000102780.17 [Q86XP1-2] ENST00000536612.3; ENSP00000445114.2; ENSG00000102780.17 [Q86XP1-3] ENST00000628433.2; ENSP00000485809.1; ENSG00000102780.17 [Q86XP1-5] |
GeneIDi | 160851 |
KEGGi | hsa:160851 |
MANE-Selecti | ENST00000337343.9; ENSP00000337572.4; NM_178009.5; NP_821077.1 |
UCSCi | uc001uyl.3, human [Q86XP1-1] |
Organism-specific databases
CTDi | 160851 |
DisGeNETi | 160851 |
GeneCardsi | DGKH |
HGNCi | HGNC:2854, DGKH |
HPAi | ENSG00000102780, Tissue enhanced (brain) |
MIMi | 604071, gene |
neXtProti | NX_Q86XP1 |
OpenTargetsi | ENSG00000102780 |
PharmGKBi | PA27315 |
VEuPathDBi | HostDB:ENSG00000102780 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG1170, Eukaryota |
GeneTreei | ENSGT00940000158106 |
HOGENOMi | CLU_001799_3_0_1 |
InParanoidi | Q86XP1 |
OMAi | FERAHTR |
OrthoDBi | 43384at2759 |
PhylomeDBi | Q86XP1 |
TreeFami | TF313104 |
Enzyme and pathway databases
UniPathwayi | UPA00230 |
BRENDAi | 2.7.1.107, 2681 |
PathwayCommonsi | Q86XP1 |
Reactomei | R-HSA-114508, Effects of PIP2 hydrolysis |
SignaLinki | Q86XP1 |
Miscellaneous databases
BioGRID-ORCSi | 160851, 15 hits in 1081 CRISPR screens |
ChiTaRSi | DGKH, human |
GenomeRNAii | 160851 |
Pharosi | Q86XP1, Tbio |
PROi | PR:Q86XP1 |
RNActi | Q86XP1, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000102780, Expressed in dorsal root ganglion and 207 other tissues |
ExpressionAtlasi | Q86XP1, baseline and differential |
Genevisiblei | Q86XP1, HS |
Family and domain databases
CDDi | cd00029, C1, 2 hits |
Gene3Di | 1.10.150.50, 1 hit 2.30.29.30, 1 hit 3.40.50.10330, 1 hit |
InterProi | View protein in InterPro IPR017438, ATP-NAD_kinase_N IPR046349, C1-like_sf IPR037607, DGK IPR000756, Diacylglycerol_kin_accessory IPR001206, Diacylglycerol_kinase_cat_dom IPR016064, NAD/diacylglycerol_kinase_sf IPR002219, PE/DAG-bd IPR011993, PH-like_dom_sf IPR001849, PH_domain IPR001660, SAM IPR013761, SAM/pointed_sf |
PANTHERi | PTHR11255, PTHR11255, 1 hit |
Pfami | View protein in Pfam PF00130, C1_1, 2 hits PF00609, DAGK_acc, 1 hit PF00781, DAGK_cat, 1 hit PF00169, PH, 1 hit PF07647, SAM_2, 1 hit |
SMARTi | View protein in SMART SM00109, C1, 2 hits SM00045, DAGKa, 1 hit SM00046, DAGKc, 1 hit SM00233, PH, 1 hit SM00454, SAM, 1 hit |
SUPFAMi | SSF111331, SSF111331, 1 hit SSF47769, SSF47769, 1 hit SSF57889, SSF57889, 2 hits |
PROSITEi | View protein in PROSITE PS50146, DAGK, 1 hit PS50003, PH_DOMAIN, 1 hit PS50105, SAM_DOMAIN, 1 hit PS00479, ZF_DAG_PE_1, 2 hits PS50081, ZF_DAG_PE_2, 2 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | DGKH_HUMAN | |
Accessioni | Q86XP1Primary (citable) accession number: Q86XP1 Secondary accession number(s): A2A2W7 Q8N7J9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 13, 2006 |
Last sequence update: | June 1, 2003 | |
Last modified: | May 25, 2022 | |
This is version 157 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 13
Human chromosome 13: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families