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Entry version 134 (11 Dec 2019)
Sequence version 3 (28 Mar 2018)
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Protein

Zinc finger protein 761

Gene

ZNF761

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri215 – 237C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri242 – 264C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri270 – 292C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri298 – 320C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri326 – 348C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri354 – 376C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri382 – 404C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri410 – 432C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri438 – 460C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri466 – 488C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri494 – 516C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri522 – 544C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri550 – 572C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri578 – 600C2H2-type 14; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri606 – 628C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri634 – 656C2H2-type 16PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri662 – 684C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri690 – 712C2H2-type 18PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri718 – 740C2H2-type 19PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436 Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 761
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF761
Synonyms:KIAA2033
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000160336.14

Human Gene Nomenclature Database

More...
HGNCi
HGNC:23179 ZNF761

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q86XN6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000160336

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA145149911

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q86XN6 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF761

Domain mapping of disease mutations (DMDM)

More...
DMDMi
158706491

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003068801 – 746Zinc finger protein 761Add BLAST746

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki205Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q86XN6

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q86XN6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q86XN6

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q86XN6

PeptideAtlas

More...
PeptideAtlasi
Q86XN6

PRoteomics IDEntifications database

More...
PRIDEi
Q86XN6

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q86XN6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q86XN6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000160336 Expressed in 88 organ(s), highest expression level in prostate gland

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q86XN6 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
132744, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q86XN6, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000480218

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q86XN6 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q86XN6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini8 – 81KRABPROSITE-ProRule annotationAdd BLAST74

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri215 – 237C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri242 – 264C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri270 – 292C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri298 – 320C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri326 – 348C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri354 – 376C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri382 – 404C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri410 – 432C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri438 – 460C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri466 – 488C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri494 – 516C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri522 – 544C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri550 – 572C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri578 – 600C2H2-type 14; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri606 – 628C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri634 – 656C2H2-type 16PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri662 – 684C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri690 – 712C2H2-type 18PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri718 – 740C2H2-type 19PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00970000193359

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q86XN6

KEGG Orthology (KO)

More...
KOi
K09228

Identification of Orthologs from Complete Genome Data

More...
OMAi
DQSHARN

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q86XN6

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765 KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 12 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 19 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 10 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 17 hits
PS50157 ZINC_FINGER_C2H2_2, 19 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q86XN6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAFSQGLLTF RDVAIEFSQE EWKCLDPAQR TLYRDVMLEN YRNLVSLDIS
60 70 80 90 100
SKCTMKEFLS TAQGNREVFH AGTLQIHESH HNGDFCYQDV DKDIHDYEFQ
110 120 130 140 150
WQEDERNGHE APMTKIKKLT GITERYDQSH ARNKPIKDQL GSSFHSHLPE
160 170 180 190 200
MHIFQTEEKI DNQVVKSVHD ASLVSTAQRI SCRPKTHISN NHGNNFWNSS
210 220 230 240 250
LLTQKQEVHM REKSFQCNES GKAFNYSSLL RKHQIIHLAD KYKCDVCGKL
260 270 280 290 300
FNQKRNLACH RRCHTGENPY KCNECGKTFS QTSSLTCHRR LHTGEKPYKC
310 320 330 340 350
EECDKAFHFK SILERHRIIH TEEKPYKCNE CGKTFRQKSI LTRHHRLHTG
360 370 380 390 400
EKPYKCNECG KTFSHKSSLT CHHRLHTGEK PYKCNECGKT FSHKSSLTCH
410 420 430 440 450
RRLHTGEKPY KCEECDKAYS FRSNFEIHRK IHTEDNAYKC NECGKTFSRT
460 470 480 490 500
SSLTCHRRRH TGEQPYKCEE CDKAFRFKSN LERHRRIHTG EKPYKCNECG
510 520 530 540 550
KTFSRKSYLT CHHRLHTGEK AYKCNECGKT FSWKSSLTCH RRLHSGEKPY
560 570 580 590 600
KCKECGKTFN QQLTLKRHRR LHSGENPYKC EDSDKAYSFK SNLEIHQKIH
610 620 630 640 650
TEENPYKCNE CGKTFSRTSS LTCHRRLHTG EKPYKCEECD KAFRVKSNLE
660 670 680 690 700
GHRRIHTGEK PYKCNECGKT FSRKSYFICH HRLHTGEKPY KCNECGKNFS
710 720 730 740
QKSSLICHHR LHTGEKPYKC NECGKTFSQK SNLTCHRRLH TGEKQV
Length:746
Mass (Da):87,716
Last modified:March 28, 2018 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7DE0524FF2673CA0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q6IQ01Q6IQ01_HUMAN
ZNF761 protein
ZNF761
70Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WYY7A0A087WYY7_HUMAN
Zinc finger protein 761
ZNF761
19Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC67660 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence BAD18456 differs from that shown. Aberrant splicing in the N-terminal part.Curated
The sequence BAD18456 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti317R → S in BAD18456 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_035335122I → S2 PublicationsCorresponds to variant dbSNP:rs2708743Ensembl.1
Natural variantiVAR_035336168V → I2 PublicationsCorresponds to variant dbSNP:rs1984432Ensembl.1
Natural variantiVAR_035337528G → S1 PublicationCorresponds to variant dbSNP:rs2708742Ensembl.1
Natural variantiVAR_035338603E → Q1 PublicationCorresponds to variant dbSNP:rs2617726Ensembl.1
Natural variantiVAR_080210678I → V1 PublicationCorresponds to variant dbSNP:rs139713552Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB107355 mRNA Translation: BAC67660.2 Different initiation.
AC022137 Genomic DNA No translation available.
KF495723 Genomic DNA No translation available.
AK131281 mRNA Translation: BAD18456.1 Sequence problems.

NCBI Reference Sequences

More...
RefSeqi
NP_001008401.3, NM_001008401.3
NP_001276880.1, NM_001289951.1
NP_001276881.1, NM_001289952.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000432094; ENSP00000480218; ENSG00000160336
ENST00000454407; ENSP00000481272; ENSG00000160336

Database of genes from NCBI RefSeq genomes

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GeneIDi
388561

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:388561

UCSC genome browser

More...
UCSCi
uc032icc.1 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB107355 mRNA Translation: BAC67660.2 Different initiation.
AC022137 Genomic DNA No translation available.
KF495723 Genomic DNA No translation available.
AK131281 mRNA Translation: BAD18456.1 Sequence problems.
RefSeqiNP_001008401.3, NM_001008401.3
NP_001276880.1, NM_001289951.1
NP_001276881.1, NM_001289952.1

3D structure databases

SMRiQ86XN6
ModBaseiSearch...

Protein-protein interaction databases

BioGridi132744, 2 interactors
IntActiQ86XN6, 1 interactor
STRINGi9606.ENSP00000480218

PTM databases

iPTMnetiQ86XN6
PhosphoSitePlusiQ86XN6

Polymorphism and mutation databases

BioMutaiZNF761
DMDMi158706491

Proteomic databases

EPDiQ86XN6
jPOSTiQ86XN6
MassIVEiQ86XN6
MaxQBiQ86XN6
PeptideAtlasiQ86XN6
PRIDEiQ86XN6

Genome annotation databases

EnsembliENST00000432094; ENSP00000480218; ENSG00000160336
ENST00000454407; ENSP00000481272; ENSG00000160336
GeneIDi388561
KEGGihsa:388561
UCSCiuc032icc.1 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
388561
EuPathDBiHostDB:ENSG00000160336.14

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF761
HGNCiHGNC:23179 ZNF761
neXtProtiNX_Q86XN6
OpenTargetsiENSG00000160336
PharmGKBiPA145149911

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00970000193359
InParanoidiQ86XN6
KOiK09228
OMAiDQSHARN
PhylomeDBiQ86XN6

Enzyme and pathway databases

ReactomeiR-HSA-212436 Generic Transcription Pathway

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
388561
PharosiQ86XN6 Tdark

Protein Ontology

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PROi
PR:Q86XN6
RNActiQ86XN6 protein

Gene expression databases

BgeeiENSG00000160336 Expressed in 88 organ(s), highest expression level in prostate gland
ExpressionAtlasiQ86XN6 baseline and differential

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 12 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 19 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 10 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 17 hits
PS50157 ZINC_FINGER_C2H2_2, 19 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN761_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86XN6
Secondary accession number(s): A0A087WXT7, Q6ZNB9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: March 28, 2018
Last modified: December 11, 2019
This is version 134 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
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