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Entry version 122 (13 Feb 2019)
Sequence version 1 (01 Jun 2003)
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Protein

GAS2-like protein 3

Gene

GAS2L3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Cytoskeletal linker protein. May promote and stabilize the formation of the actin and microtubule network.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • actin binding Source: UniProtKB
  • microtubule binding Source: UniProtKB

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
GAS2-like protein 3
Alternative name(s):
Growth arrest-specific protein 2-like 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GAS2L3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000139354.10

Human Gene Nomenclature Database

More...
HGNCi
HGNC:27475 GAS2L3

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q86XJ1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Microtubule

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000139354

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134979032

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
GAS2L3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
73919616

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001904461 – 694GAS2-like protein 3Add BLAST694

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei441PhosphothreonineCombined sources1
Modified residuei570PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q86XJ1

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q86XJ1

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q86XJ1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q86XJ1

PeptideAtlas

More...
PeptideAtlasi
Q86XJ1

PRoteomics IDEntifications database

More...
PRIDEi
Q86XJ1

ProteomicsDB human proteome resource

More...
ProteomicsDBi
70285

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q86XJ1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q86XJ1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in the pancreas, heart, liver, placenta, brain, skeletal muscle, kidney and lung.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000139354 Expressed in 162 organ(s), highest expression level in trigeminal ganglion

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q86XJ1 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q86XJ1 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA048593

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (via CH domain) with F-actin. Interacts (via C terminus) with microtubules.1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
129559, 15 interactors

Protein interaction database and analysis system

More...
IntActi
Q86XJ1, 10 interactors

Molecular INTeraction database

More...
MINTi
Q86XJ1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q86XJ1

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q86XJ1

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini48 – 168Calponin-homology (CH)PROSITE-ProRule annotationAdd BLAST121
Domaini208 – 281GARPROSITE-ProRule annotationAdd BLAST74

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The GAR domain modulates the binding strength to each cytoskeletal network.1 Publication

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the GAS2 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IQBS Eukaryota
ENOG410Z7C5 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159389

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000059643

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG005805

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q86XJ1

Identification of Orthologs from Complete Genome Data

More...
OMAi
SAVSMFQ

Database of Orthologous Groups

More...
OrthoDBi
1343422at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q86XJ1

TreeFam database of animal gene trees

More...
TreeFami
TF323754

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00014 CH, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.418.10, 1 hit
3.30.920.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR003108 GAR_dom
IPR036534 GAR_dom_sf
IPR029932 GAS2L3

The PANTHER Classification System

More...
PANTHERi
PTHR44885 PTHR44885, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00307 CH, 1 hit
PF02187 GAS2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00033 CH, 1 hit
SM00243 GAS2, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF143575 SSF143575, 1 hit
SSF47576 SSF47576, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50021 CH, 1 hit
PS51460 GAR, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q86XJ1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQPAIQVWFG EDLPLSPRSP LTPRHGPGLA NVCQYDEWIA VRHEATLLPM
60 70 80 90 100
QEDLSIWLSG LLGIKVKAEK LLEELDNGVL LCQLIDVLQN MVKTCNSEES
110 120 130 140 150
GNFPMRKVPC KKDAASGSFF ARDNTANFLH WCRDIGVDET YLFESEGLVL
160 170 180 190 200
HKDPRQVYLC LLEIGRIVSR YGVEPPVLVK LEKEIELEET LLNTSGPEDS
210 220 230 240 250
ISIPKSCCRH EELHEAVKHI AEDPPCSCSH RFSIEYLSEG RYRLGDKILF
260 270 280 290 300
IRMLHGKHVM VRVGGGWDTL QGFLLKYDPC RILQFATLEQ KILAFQKGVS
310 320 330 340 350
NESVPDSPAR TPQPPEMNPL SAVNMFQKQN SKPSVPVSIP KSKEKQGRPP
360 370 380 390 400
GALVPASSLK GGNLGSMSVR SKLPNSPAAS SHPKLKSSKG ITKKPQAPSN
410 420 430 440 450
NASSSLASLN PVGKNTSSPA LPRTAPCISE SPRKCISSPN TPKAKVIPAQ
460 470 480 490 500
NSADLPESTL LPNKCSGKTQ PKYLKHNHIS SRDNAVSHLA AHSNSSSKCP
510 520 530 540 550
KLPKANIPVR PKPSFQSSAK MTKTSSKTIA TGLGTQSQPS DGAPQAKPVP
560 570 580 590 600
AQKLKSALNL NQPVSVSSVS PVKATQKSKD KNIVSATKKQ PQNKSAFQKT
610 620 630 640 650
GPSSLKSPGR TPLSIVSLPQ SSTKTQTAPK SAQTVAKSQH STKGPPRSGK
660 670 680 690
TPASIRKPPS SVKDADSGDK KPTAKKKEDD DHYFVMTGSK KPRK
Length:694
Mass (Da):75,214
Last modified:June 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFF20533B5A0D4844
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3V1N3G3V1N3_HUMAN
GAS2-like protein 3
GAS2L3 hCG_21805
590Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YIT6H0YIT6_HUMAN
GAS2-like protein 3
GAS2L3
391Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8VSB7F8VSB7_HUMAN
GAS2-like protein 3
GAS2L3
49Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_033944461L → S. Corresponds to variant dbSNP:rs11834625Ensembl.1
Natural variantiVAR_033945500P → T. Corresponds to variant dbSNP:rs17030365Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK315189 mRNA Translation: BAG37629.1
CH471054 Genomic DNA Translation: EAW97641.1
BC043366 mRNA Translation: AAH43366.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS9079.1

NCBI Reference Sequences

More...
RefSeqi
NP_001290059.1, NM_001303130.1
NP_777602.1, NM_174942.2
XP_005268861.1, XM_005268804.3
XP_011536521.1, XM_011538219.2
XP_011536522.1, XM_011538220.2
XP_011536523.1, XM_011538221.2
XP_016874695.1, XM_017019206.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.20575
Hs.547389

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000266754; ENSP00000266754; ENSG00000139354
ENST00000539410; ENSP00000439672; ENSG00000139354
ENST00000547754; ENSP00000448955; ENSG00000139354

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
283431

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:283431

UCSC genome browser

More...
UCSCi
uc001thu.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK315189 mRNA Translation: BAG37629.1
CH471054 Genomic DNA Translation: EAW97641.1
BC043366 mRNA Translation: AAH43366.1
CCDSiCCDS9079.1
RefSeqiNP_001290059.1, NM_001303130.1
NP_777602.1, NM_174942.2
XP_005268861.1, XM_005268804.3
XP_011536521.1, XM_011538219.2
XP_011536522.1, XM_011538220.2
XP_011536523.1, XM_011538221.2
XP_016874695.1, XM_017019206.1
UniGeneiHs.20575
Hs.547389

3D structure databases

ProteinModelPortaliQ86XJ1
SMRiQ86XJ1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi129559, 15 interactors
IntActiQ86XJ1, 10 interactors
MINTiQ86XJ1

PTM databases

iPTMnetiQ86XJ1
PhosphoSitePlusiQ86XJ1

Polymorphism and mutation databases

BioMutaiGAS2L3
DMDMi73919616

Proteomic databases

EPDiQ86XJ1
jPOSTiQ86XJ1
MaxQBiQ86XJ1
PaxDbiQ86XJ1
PeptideAtlasiQ86XJ1
PRIDEiQ86XJ1
ProteomicsDBi70285

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000266754; ENSP00000266754; ENSG00000139354
ENST00000539410; ENSP00000439672; ENSG00000139354
ENST00000547754; ENSP00000448955; ENSG00000139354
GeneIDi283431
KEGGihsa:283431
UCSCiuc001thu.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
283431
EuPathDBiHostDB:ENSG00000139354.10

GeneCards: human genes, protein and diseases

More...
GeneCardsi
GAS2L3

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0018956
HGNCiHGNC:27475 GAS2L3
HPAiHPA048593
neXtProtiNX_Q86XJ1
OpenTargetsiENSG00000139354
PharmGKBiPA134979032

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IQBS Eukaryota
ENOG410Z7C5 LUCA
GeneTreeiENSGT00940000159389
HOGENOMiHOG000059643
HOVERGENiHBG005805
InParanoidiQ86XJ1
OMAiSAVSMFQ
OrthoDBi1343422at2759
PhylomeDBiQ86XJ1
TreeFamiTF323754

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
GAS2L3 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
283431

Protein Ontology

More...
PROi
PR:Q86XJ1

Gene expression databases

BgeeiENSG00000139354 Expressed in 162 organ(s), highest expression level in trigeminal ganglion
ExpressionAtlasiQ86XJ1 baseline and differential
GenevisibleiQ86XJ1 HS

Family and domain databases

CDDicd00014 CH, 1 hit
Gene3Di1.10.418.10, 1 hit
3.30.920.20, 1 hit
InterProiView protein in InterPro
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR003108 GAR_dom
IPR036534 GAR_dom_sf
IPR029932 GAS2L3
PANTHERiPTHR44885 PTHR44885, 1 hit
PfamiView protein in Pfam
PF00307 CH, 1 hit
PF02187 GAS2, 1 hit
SMARTiView protein in SMART
SM00033 CH, 1 hit
SM00243 GAS2, 1 hit
SUPFAMiSSF143575 SSF143575, 1 hit
SSF47576 SSF47576, 1 hit
PROSITEiView protein in PROSITE
PS50021 CH, 1 hit
PS51460 GAR, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGA2L3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86XJ1
Secondary accession number(s): B2RCN2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: June 1, 2003
Last modified: February 13, 2019
This is version 122 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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