Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein phosphatase 1 regulatory subunit 3B

Gene

PPP1R3B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in hepatocytes (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCarbohydrate metabolism, Glycogen metabolism

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
CBM21 Carbohydrate-Binding Module Family 21

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein phosphatase 1 regulatory subunit 3B
Alternative name(s):
Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL
Protein phosphatase 1 regulatory subunit 4
Short name:
PP1 subunit R4
Protein phosphatase 1 subunit GL
Short name:
PTG
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PPP1R3B
Synonyms:PPP1R4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000173281.4

Human Gene Nomenclature Database

More...
HGNCi
HGNC:14942 PPP1R3B

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
610541 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q86XI6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
79660

Open Targets

More...
OpenTargetsi
ENSG00000173281

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA33652

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PPP1R3B

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74727837

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003245431 – 285Protein phosphatase 1 regulatory subunit 3BAdd BLAST285

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei261PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q86XI6

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q86XI6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q86XI6

PeptideAtlas

More...
PeptideAtlasi
Q86XI6

PRoteomics IDEntifications database

More...
PRIDEi
Q86XI6

ProteomicsDB human proteome resource

More...
ProteomicsDBi
70281

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q86XI6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q86XI6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in the liver and, at lower levels, in skeletal muscle, including in vastus lateralis, gastrocnemius and soleus (at protein level). Highest mRNA levels are observed in skeletal muscle, and only moderate levels in liver and heart. Weak expression in placenta and lung.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000173281 Expressed in 188 organ(s), highest expression level in liver

CleanEx database of gene expression profiles

More...
CleanExi
HS_PPP1R3B

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q86XI6 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA028731

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with glycogen, PPP1CC catalytic subunit of PP1 and PYGL. Associates with glycogen particles. Forms complexes with debranching enzyme, glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity (By similarity).By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
PPP1CAP621363EBI-3918864,EBI-357253

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
122786, 9 interactors

Protein interaction database and analysis system

More...
IntActi
Q86XI6, 6 interactors

Molecular INTeraction database

More...
MINTi
Q86XI6

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000308318

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1285
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q86XI6

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q86XI6

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q86XI6

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini125 – 233CBM21PROSITE-ProRule annotationAdd BLAST109

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi62 – 65PP1-binding motif4

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The N-terminal region is required for binding to PP1, the central region is required for binding to glycogen and the C-terminal region is required for binding to PYGL.By similarity

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3986 Eukaryota
ENOG4111FT1 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159475

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000026799

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG052744

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q86XI6

KEGG Orthology (KO)

More...
KOi
K07189

Identification of Orthologs from Complete Genome Data

More...
OMAi
EFAVCYE

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0GB5

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q86XI6

TreeFam database of animal gene trees

More...
TreeFami
TF105537

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.2440, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005036 CBM21_dom
IPR038175 CBM21_dom_sf
IPR017434 Pase-1_reg-su_3B/C/D_met
IPR030682 PP1_3B

The PANTHER Classification System

More...
PANTHERi
PTHR12307:SF13 PTHR12307:SF13, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03370 CBM_21, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF038207 PP1_GT_animal, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51159 CBM21, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q86XI6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMAVDIEYRY NCMAPSLRQE RFAFKISPKP SKPLRPCIQL SSKNEASGMV
60 70 80 90 100
APAVQEKKVK KRVSFADNQG LALTMVKVFS EFDDPLDMPF NITELLDNIV
110 120 130 140 150
SLTTAESESF VLDFSQPSAD YLDFRNRLQA DHVCLENCVL KDKAIAGTVK
160 170 180 190 200
VQNLAFEKTV KIRMTFDTWK SYTDFPCQYV KDTYAGSDRD TFSFDISLPE
210 220 230 240 250
KIQSYERMEF AVYYECNGQT YWDSNRGKNY RIIRAELKST QGMTKPHSGP
260 270 280
DLGISFDQFG SPRCSYGLFP EWPSYLGYEK LGPYY
Length:285
Mass (Da):32,695
Last modified:June 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i77178FE100947989
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti149V → A in BAB14811 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03981448G → E. Corresponds to variant dbSNP:rs3748140Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK024067 mRNA Translation: BAB14811.1
AK096119 mRNA Translation: BAG53215.1
CH471157 Genomic DNA Translation: EAW65572.1
BC043388 mRNA Translation: AAH43388.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5973.1

NCBI Reference Sequences

More...
RefSeqi
NP_001188258.1, NM_001201329.1
NP_078883.2, NM_024607.3
XP_006716316.1, XM_006716253.3
XP_016869324.1, XM_017013835.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.458513

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000310455; ENSP00000308318; ENSG00000173281
ENST00000519699; ENSP00000428642; ENSG00000173281
ENST00000644687; ENSP00000493491; ENSG00000285343
ENST00000645121; ENSP00000494659; ENSG00000285343

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
79660

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:79660

UCSC genome browser

More...
UCSCi
uc003wsn.5 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK024067 mRNA Translation: BAB14811.1
AK096119 mRNA Translation: BAG53215.1
CH471157 Genomic DNA Translation: EAW65572.1
BC043388 mRNA Translation: AAH43388.1
CCDSiCCDS5973.1
RefSeqiNP_001188258.1, NM_001201329.1
NP_078883.2, NM_024607.3
XP_006716316.1, XM_006716253.3
XP_016869324.1, XM_017013835.1
UniGeneiHs.458513

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2EEFNMR-A105-253[»]
ProteinModelPortaliQ86XI6
SMRiQ86XI6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi122786, 9 interactors
IntActiQ86XI6, 6 interactors
MINTiQ86XI6
STRINGi9606.ENSP00000308318

Protein family/group databases

CAZyiCBM21 Carbohydrate-Binding Module Family 21

PTM databases

iPTMnetiQ86XI6
PhosphoSitePlusiQ86XI6

Polymorphism and mutation databases

BioMutaiPPP1R3B
DMDMi74727837

Proteomic databases

EPDiQ86XI6
MaxQBiQ86XI6
PaxDbiQ86XI6
PeptideAtlasiQ86XI6
PRIDEiQ86XI6
ProteomicsDBi70281

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
79660
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000310455; ENSP00000308318; ENSG00000173281
ENST00000519699; ENSP00000428642; ENSG00000173281
ENST00000644687; ENSP00000493491; ENSG00000285343
ENST00000645121; ENSP00000494659; ENSG00000285343
GeneIDi79660
KEGGihsa:79660
UCSCiuc003wsn.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
79660
DisGeNETi79660
EuPathDBiHostDB:ENSG00000173281.4

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PPP1R3B

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0007298
HGNCiHGNC:14942 PPP1R3B
HPAiHPA028731
MIMi610541 gene
neXtProtiNX_Q86XI6
OpenTargetsiENSG00000173281
PharmGKBiPA33652

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3986 Eukaryota
ENOG4111FT1 LUCA
GeneTreeiENSGT00940000159475
HOGENOMiHOG000026799
HOVERGENiHBG052744
InParanoidiQ86XI6
KOiK07189
OMAiEFAVCYE
OrthoDBiEOG091G0GB5
PhylomeDBiQ86XI6
TreeFamiTF105537

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
PPP1R3B human
EvolutionaryTraceiQ86XI6

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
79660

Protein Ontology

More...
PROi
PR:Q86XI6

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000173281 Expressed in 188 organ(s), highest expression level in liver
CleanExiHS_PPP1R3B
GenevisibleiQ86XI6 HS

Family and domain databases

Gene3Di2.60.40.2440, 1 hit
InterProiView protein in InterPro
IPR005036 CBM21_dom
IPR038175 CBM21_dom_sf
IPR017434 Pase-1_reg-su_3B/C/D_met
IPR030682 PP1_3B
PANTHERiPTHR12307:SF13 PTHR12307:SF13, 1 hit
PfamiView protein in Pfam
PF03370 CBM_21, 1 hit
PIRSFiPIRSF038207 PP1_GT_animal, 1 hit
PROSITEiView protein in PROSITE
PS51159 CBM21, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPPR3B_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86XI6
Secondary accession number(s): B3KTV3, Q9H812
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: June 1, 2003
Last modified: December 5, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again