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Protein

Condensin-2 complex subunit G2

Gene

NCAPG2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle, Cell division, DNA condensation, Mitosis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-2299718 Condensation of Prophase Chromosomes

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Condensin-2 complex subunit G2
Alternative name(s):
Chromosome-associated protein G2
Short name:
CAP-G2
Short name:
hCAP-G2
Leucine zipper protein 5
Non-SMC condensin II complex subunit G2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NCAPG2
Synonyms:LUZP5
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000146918.19

Human Gene Nomenclature Database

More...
HGNCi
HGNC:21904 NCAPG2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
608532 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q86XI2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
54892

Open Targets

More...
OpenTargetsi
ENSG00000146918

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162397212

Polymorphism and mutation databases

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74727834

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002559421 – 1143Condensin-2 complex subunit G2Add BLAST1143

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei30PhosphoserineCombined sources1
Modified residuei805PhosphothreonineCombined sources1
Modified residuei1119PhosphothreonineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q86XI2

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q86XI2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q86XI2

PeptideAtlas

More...
PeptideAtlasi
Q86XI2

PRoteomics IDEntifications database

More...
PRIDEi
Q86XI2

ProteomicsDB human proteome resource

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ProteomicsDBi
70279
70280 [Q86XI2-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q86XI2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q86XI2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000146918 Expressed in 173 organ(s), highest expression level in secondary oocyte

CleanEx database of gene expression profiles

More...
CleanExi
HS_NCAPG2

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q86XI2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q86XI2 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA026631

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the condensin-2 complex, which contains the SMC2 and SMC4 heterodimer, and 3 non SMC subunits that probably regulate the complex: NCAPH2, NCAPD3 and NCAPG2.1 Publication

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
120239, 21 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-985 Condensin II complex

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q86XI2

Database of interacting proteins

More...
DIPi
DIP-43902N

Protein interaction database and analysis system

More...
IntActi
Q86XI2, 9 interactors

Molecular INTeraction database

More...
MINTi
Q86XI2

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000348657

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q86XI2

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati460 – 498HEATAdd BLAST39

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1949 Eukaryota
ENOG410XSM3 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00490000043432

The HOVERGEN Database of Homologous Vertebrate Genes

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HOVERGENi
HBG074124

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q86XI2

KEGG Orthology (KO)

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KOi
K11492

Identification of Orthologs from Complete Genome Data

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OMAi
HCLNACI

Database of Orthologous Groups

More...
OrthoDBi
EOG091G03K6

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q86XI2

TreeFam database of animal gene trees

More...
TreeFami
TF101163

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR024741 Condensin2_G2

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12422 Condensin2nSMC, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q86XI2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEKRETFVQA VSKELVGEFL QFVQLDKEAS DPFSLNELLD ELSRKQKEEL
60 70 80 90 100
WQRLKNLLTD VLLESPVDGW QVVEAQGEDN METEHGSKMR KSIEIIYAIT
110 120 130 140 150
SVILASVSVI NESENYEALL ECVIILNGIL YALPESERKL QSSIQDLCVT
160 170 180 190 200
WWEKGLPAKE DTGKTAFVML LRRSLETKTG ADVCRLWRIH QALYCFDYDL
210 220 230 240 250
EESGEIKDML LECFININYI KKEEGRRFLS CLFNWNINFI KMIHGTIKNQ
260 270 280 290 300
LQGLQKSLMV YIAEIYFRAW KKASGKILEA IENDCIQDFM FHGIHLPRRS
310 320 330 340 350
PVHSKVREVL SYFHHQKKVR QGVEEMLYRL YKPILWRGLK ARNSEVRSNA
360 370 380 390 400
ALLFVEAFPI RDPNLHAIEM DSEIQKQFEE LYSLLEDPYP MVRSTGILGV
410 420 430 440 450
CKITSKYWEM MPPTILIDLL KKVTGELAFD TSSADVRCSV FKCLPMILDN
460 470 480 490 500
KLSHPLLEQL LPALRYSLHD NSEKVRVAFV DMLLKIKAVR AAKFWKICPM
510 520 530 540 550
EHILVRLETD SRPVSRRLVS LIFNSFLPVN QPEEVWCERC VTLVQMNHAA
560 570 580 590 600
ARRFYQYAHE HTACTNIAKL IHVIRHCLNA CIQRAVREPP EDEEEEDGRE
610 620 630 640 650
KENVTVLDKT LSVNDVACMA GLLEIIVILW KSIDRSMENN KEAKLYTINK
660 670 680 690 700
FASVLPEYLK VFKDDRCKIP LFMLMSFMPA SAVPPFSCGV ISTLRSREEG
710 720 730 740 750
AVDKSYCTLL DCLCSWGQVG HILELVDNWL PTEHAQAKSN TASKGRVQIH
760 770 780 790 800
DTRPVKPELA LVYIEYLLTH PKNRECLLSA PRKKLNHLLK ALETSKADLE
810 820 830 840 850
SLLQTPGGKP RGFSEAAAPR AFGLHCRLSI HLQHKFCSEG KVYLSMLEDT
860 870 880 890 900
GFWLESKILS FIQDQEEDYL KLHRVIYQQI IQTYLTVCKD VVMVGLGDHQ
910 920 930 940 950
FQMQLLQRSL GIMQTVKGFF YVSLLLDILK EITGSSLIQK TDSDEEVAML
960 970 980 990 1000
LDTVQKVFQK MLECIARSFR KQPEEGLRLL YSVQRPLHEF ITAVQSRHTD
1010 1020 1030 1040 1050
TPVHRGVLST LIAGPVVEIS HQLRKVSDVE ELTPPEHLSD LPPFSRCLIG
1060 1070 1080 1090 1100
IIIKSSNVVR SFLDELKACV ASNDIEGIVC LTAAVHIILV INAGKHKSSK
1110 1120 1130 1140
VREVAATVHR KLKTFMEITL EEDSIERFLY ESSSRTLGEL LNS
Length:1,143
Mass (Da):130,960
Last modified:June 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7C7B7FA2A7F0683C
GO
Isoform 2 (identifier: Q86XI2-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1128-1143: FLYESSSRTLGELLNS → YEDLLCCPGWALTPGLLDSIYPSASVPIG

Show »
Length:1,156
Mass (Da):132,196
Checksum:iC0BAFFC159FEB783
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0Y6U5H0Y6U5_HUMAN
Condensin-2 complex subunit G2
NCAPG2
898Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WE06F8WE06_HUMAN
Condensin-2 complex subunit G2
NCAPG2
389Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH20560 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAB14219 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAB14534 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti369E → G in BAB14219 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_053046794T → M. Corresponds to variant dbSNP:rs10248318Ensembl.1
Natural variantiVAR_053047867E → D. Corresponds to variant dbSNP:rs3214000Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0213111128 – 1143FLYES…ELLNS → YEDLLCCPGWALTPGLLDSI YPSASVPIG in isoform 2. 1 PublicationAdd BLAST16

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX537845 mRNA Translation: CAD97854.1
CH236954 Genomic DNA Translation: EAL23929.1
BC005878 mRNA Translation: AAH05878.2
BC020560 mRNA Translation: AAH20560.1 Different initiation.
BC043404 mRNA Translation: AAH43404.1
AK022744 mRNA Translation: BAB14219.1 Different initiation.
AK023347 mRNA Translation: BAB14534.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS43686.1 [Q86XI2-1]
CCDS64816.1 [Q86XI2-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001268861.1, NM_001281932.1 [Q86XI2-1]
NP_001268862.1, NM_001281933.1 [Q86XI2-2]
NP_060230.5, NM_017760.6 [Q86XI2-1]
XP_011514658.1, XM_011516356.2 [Q86XI2-2]
XP_011514659.1, XM_011516357.2 [Q86XI2-2]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.18616

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000356309; ENSP00000348657; ENSG00000146918 [Q86XI2-1]
ENST00000409339; ENSP00000387007; ENSG00000146918 [Q86XI2-2]
ENST00000409423; ENSP00000386569; ENSG00000146918 [Q86XI2-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
54892

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:54892

UCSC genome browser

More...
UCSCi
uc003wnv.3 human [Q86XI2-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX537845 mRNA Translation: CAD97854.1
CH236954 Genomic DNA Translation: EAL23929.1
BC005878 mRNA Translation: AAH05878.2
BC020560 mRNA Translation: AAH20560.1 Different initiation.
BC043404 mRNA Translation: AAH43404.1
AK022744 mRNA Translation: BAB14219.1 Different initiation.
AK023347 mRNA Translation: BAB14534.1 Different initiation.
CCDSiCCDS43686.1 [Q86XI2-1]
CCDS64816.1 [Q86XI2-2]
RefSeqiNP_001268861.1, NM_001281932.1 [Q86XI2-1]
NP_001268862.1, NM_001281933.1 [Q86XI2-2]
NP_060230.5, NM_017760.6 [Q86XI2-1]
XP_011514658.1, XM_011516356.2 [Q86XI2-2]
XP_011514659.1, XM_011516357.2 [Q86XI2-2]
UniGeneiHs.18616

3D structure databases

ProteinModelPortaliQ86XI2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi120239, 21 interactors
ComplexPortaliCPX-985 Condensin II complex
CORUMiQ86XI2
DIPiDIP-43902N
IntActiQ86XI2, 9 interactors
MINTiQ86XI2
STRINGi9606.ENSP00000348657

PTM databases

iPTMnetiQ86XI2
PhosphoSitePlusiQ86XI2

Polymorphism and mutation databases

DMDMi74727834

Proteomic databases

EPDiQ86XI2
MaxQBiQ86XI2
PaxDbiQ86XI2
PeptideAtlasiQ86XI2
PRIDEiQ86XI2
ProteomicsDBi70279
70280 [Q86XI2-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
54892
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000356309; ENSP00000348657; ENSG00000146918 [Q86XI2-1]
ENST00000409339; ENSP00000387007; ENSG00000146918 [Q86XI2-2]
ENST00000409423; ENSP00000386569; ENSG00000146918 [Q86XI2-1]
GeneIDi54892
KEGGihsa:54892
UCSCiuc003wnv.3 human [Q86XI2-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
54892
DisGeNETi54892
EuPathDBiHostDB:ENSG00000146918.19

GeneCards: human genes, protein and diseases

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GeneCardsi
NCAPG2
HGNCiHGNC:21904 NCAPG2
HPAiHPA026631
MIMi608532 gene
neXtProtiNX_Q86XI2
OpenTargetsiENSG00000146918
PharmGKBiPA162397212

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG1949 Eukaryota
ENOG410XSM3 LUCA
GeneTreeiENSGT00490000043432
HOVERGENiHBG074124
InParanoidiQ86XI2
KOiK11492
OMAiHCLNACI
OrthoDBiEOG091G03K6
PhylomeDBiQ86XI2
TreeFamiTF101163

Enzyme and pathway databases

ReactomeiR-HSA-2299718 Condensation of Prophase Chromosomes

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
NCAPG2 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
NCAPG2

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
54892

Protein Ontology

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PROi
PR:Q86XI2

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000146918 Expressed in 173 organ(s), highest expression level in secondary oocyte
CleanExiHS_NCAPG2
ExpressionAtlasiQ86XI2 baseline and differential
GenevisibleiQ86XI2 HS

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR024741 Condensin2_G2
PfamiView protein in Pfam
PF12422 Condensin2nSMC, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCNDG2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86XI2
Secondary accession number(s): A4D228
, Q7Z3J9, Q8WUG8, Q9BRX6, Q9H8S2, Q9H9K6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: June 1, 2003
Last modified: December 5, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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Main funding by: National Institutes of Health

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