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Entry version 131 (08 May 2019)
Sequence version 2 (30 Aug 2005)
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Protein

AN1-type zinc finger protein 4

Gene

ZFAND4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

A report observed N-glycosylation at Asn-235 (PubMed:19139490). However, as the protein is not predicted to localize in an extracellular compartment of the cell, additional evidence is required to confirm this result.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri664 – 708AN1-typePROSITE-ProRule annotationAdd BLAST45

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
AN1-type zinc finger protein 4
Alternative name(s):
AN1-type zinc finger and ubiquitin domain-containing protein-like 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZFAND4
Synonyms:ANUBL1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:23504 ZFAND4

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q86XD8

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
93550

Open Targets

More...
OpenTargetsi
ENSG00000172671

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134976557

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZFAND4

Domain mapping of disease mutations (DMDM)

More...
DMDMi
121944435

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002698921 – 727AN1-type zinc finger protein 4Add BLAST727

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q86XD8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q86XD8

PRoteomics IDEntifications database

More...
PRIDEi
Q86XD8

ProteomicsDB human proteome resource

More...
ProteomicsDBi
70266

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q86XD8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q86XD8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000172671 Expressed in 160 organ(s), highest expression level in sperm

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q86XD8 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q86XD8 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA037839
HPA057543

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
125033, 3 interactors

Protein interaction database and analysis system

More...
IntActi
Q86XD8, 2 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000339484

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q86XD8

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini28 – 103Ubiquitin-likePROSITE-ProRule annotationAdd BLAST76

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri664 – 708AN1-typePROSITE-ProRule annotationAdd BLAST45

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0001 Eukaryota
KOG3173 Eukaryota
COG5272 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155716

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000033974

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q86XD8

KEGG Orthology (KO)

More...
KOi
K12163

Identification of Orthologs from Complete Genome Data

More...
OMAi
YECRCGN

Database of Orthologous Groups

More...
OrthoDBi
1551371at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q86XD8

TreeFam database of animal gene trees

More...
TreeFami
TF329607

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
4.10.1110.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR035896 AN1-like_Znf
IPR019956 Ubiquitin
IPR029071 Ubiquitin-like_domsf
IPR000626 Ubiquitin_dom
IPR000058 Znf_AN1

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00240 ubiquitin, 1 hit
PF01428 zf-AN1, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00348 UBIQUITIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00213 UBQ, 1 hit
SM00154 ZnF_AN1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF118310 SSF118310, 1 hit
SSF54236 SSF54236, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50053 UBIQUITIN_2, 1 hit
PS51039 ZF_AN1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q86XD8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDNRKEPPFF NDDNMGPFYY RLHFCDTMEL FIETLTGTCF ELRVSPFETV
60 70 80 90 100
ISVKAKIRRL EGIPICRQHL IWNNMELEND YCLNDYNISE GCTLKLVLAM
110 120 130 140 150
RGGPINTRRV PTDDPLRKMA EYLDSSRVEV WEKTSCSKQV TFLVYQEGDQ
160 170 180 190 200
LNFFPAVDRG DGTLTPLSDS SKKIDFHLHV LRRKGEHRMS GGSMYNSDTD
210 220 230 240 250
EDEETEPSSS GQQIIENSIT MNKMKLLKAK MKNMNLSKKP KKAVKIKPHP
260 270 280 290 300
PVAPRPSSGS TAPSRHRLLR VLPNIGQSCS PAFGNAYPPE ISRNGISSLA
310 320 330 340 350
TQLSAERYIS SITGEFLKED NSWENNTLSH FSSNVKLPPQ IPHLELGNDQ
360 370 380 390 400
ELADSVLHLG SSLPRQTKHF LGNLPSSNGN IVLPSEECVT EQSLLPKVGS
410 420 430 440 450
LASFAEGNAD EQSSGLEGAC KVNLELLLTN ADKGLKAPEQ HLKHVAGVLN
460 470 480 490 500
GESVETSVLN YRELSPHKNR LLSPLRCSAP MSLHNSLVKP ERQSKCFEFG
510 520 530 540 550
KLQPSSSQSL DVQNITDSSF SRTTCFQGVK VDSLGKRSDV ISKVEARDIT
560 570 580 590 600
EMTNKASKEP VGCVNNISFL ASLAGSTSRN RLQSTRGAGR LQNSGTGLST
610 620 630 640 650
NLQHFQEENF RKSSPQLEHT GVFLSTHGVG MNGNNAAAGK SVGECTTHHL
660 670 680 690 700
PPVKAPLQTK KKTTNHCFLC GKKTGLASSY ECRCGNNFCA SHRYAETHGC
710 720
TYDYKSAGRR YLHEANPVVN APKLPKI
Length:727
Mass (Da):80,358
Last modified:August 30, 2005 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3D162959CFFC544C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
J3KPC0J3KPC0_HUMAN
AN1-type zinc finger protein 4
ZFAND4
653Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5VVY4Q5VVY4_HUMAN
AN1-type zinc finger protein 4
ZFAND4
224Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F2Z2H4F2Z2H4_HUMAN
AN1-type zinc finger protein 4
ZFAND4
211Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WT56A0A087WT56_HUMAN
AN1-type zinc finger protein 4
ZFAND4
93Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_053773118K → T1 PublicationCorresponds to variant dbSNP:rs17854567Ensembl.1
Natural variantiVAR_053774358H → Y. Corresponds to variant dbSNP:rs12267385Ensembl.1
Natural variantiVAR_062163523T → A. Corresponds to variant dbSNP:rs34082391Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK292469 mRNA Translation: BAF85158.1
AK314395 mRNA Translation: BAG37019.1
AL445201 Genomic DNA No translation available.
CH471160 Genomic DNA Translation: EAW86653.1
BC045587 mRNA Translation: AAH45587.2

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS7214.1

NCBI Reference Sequences

More...
RefSeqi
NP_001121796.1, NM_001128324.2
NP_001269835.1, NM_001282906.1
NP_777550.2, NM_174890.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000344646; ENSP00000339484; ENSG00000172671

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
93550

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:93550

UCSC genome browser

More...
UCSCi
uc001jcm.6 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK292469 mRNA Translation: BAF85158.1
AK314395 mRNA Translation: BAG37019.1
AL445201 Genomic DNA No translation available.
CH471160 Genomic DNA Translation: EAW86653.1
BC045587 mRNA Translation: AAH45587.2
CCDSiCCDS7214.1
RefSeqiNP_001121796.1, NM_001128324.2
NP_001269835.1, NM_001282906.1
NP_777550.2, NM_174890.3

3D structure databases

SMRiQ86XD8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi125033, 3 interactors
IntActiQ86XD8, 2 interactors
STRINGi9606.ENSP00000339484

PTM databases

iPTMnetiQ86XD8
PhosphoSitePlusiQ86XD8

Polymorphism and mutation databases

BioMutaiZFAND4
DMDMi121944435

Proteomic databases

jPOSTiQ86XD8
PaxDbiQ86XD8
PRIDEiQ86XD8
ProteomicsDBi70266

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
93550
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000344646; ENSP00000339484; ENSG00000172671
GeneIDi93550
KEGGihsa:93550
UCSCiuc001jcm.6 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
93550
DisGeNETi93550

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZFAND4
HGNCiHGNC:23504 ZFAND4
HPAiHPA037839
HPA057543
neXtProtiNX_Q86XD8
OpenTargetsiENSG00000172671
PharmGKBiPA134976557

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0001 Eukaryota
KOG3173 Eukaryota
COG5272 LUCA
GeneTreeiENSGT00940000155716
HOGENOMiHOG000033974
InParanoidiQ86XD8
KOiK12163
OMAiYECRCGN
OrthoDBi1551371at2759
PhylomeDBiQ86XD8
TreeFamiTF329607

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ZFAND4 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
93550

Protein Ontology

More...
PROi
PR:Q86XD8

Gene expression databases

BgeeiENSG00000172671 Expressed in 160 organ(s), highest expression level in sperm
ExpressionAtlasiQ86XD8 baseline and differential
GenevisibleiQ86XD8 HS

Family and domain databases

Gene3Di4.10.1110.10, 1 hit
InterProiView protein in InterPro
IPR035896 AN1-like_Znf
IPR019956 Ubiquitin
IPR029071 Ubiquitin-like_domsf
IPR000626 Ubiquitin_dom
IPR000058 Znf_AN1
PfamiView protein in Pfam
PF00240 ubiquitin, 1 hit
PF01428 zf-AN1, 1 hit
PRINTSiPR00348 UBIQUITIN
SMARTiView protein in SMART
SM00213 UBQ, 1 hit
SM00154 ZnF_AN1, 1 hit
SUPFAMiSSF118310 SSF118310, 1 hit
SSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50053 UBIQUITIN_2, 1 hit
PS51039 ZF_AN1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZFAN4_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86XD8
Secondary accession number(s): A8K8V4, B2RAX2, Q5VVY5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: August 30, 2005
Last modified: May 8, 2019
This is version 131 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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