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Entry version 117 (10 Feb 2021)
Sequence version 2 (23 Oct 2007)
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Protein

Cerebellar degeneration-related protein 2-like

Gene

CDR2L

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q86X02

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cerebellar degeneration-related protein 2-like
Alternative name(s):
Paraneoplastic 62 kDa antigen
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CDR2L
Synonyms:HUMPPA
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29999, CDR2L

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q86X02

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000109089.7

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
30850

Open Targets

More...
OpenTargetsi
ENSG00000109089

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142672137

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q86X02, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CDR2L

Domain mapping of disease mutations (DMDM)

More...
DMDMi
160017566

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003072341 – 465Cerebellar degeneration-related protein 2-likeAdd BLAST465

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei308PhosphoserineCombined sources1
Modified residuei318PhosphoserineCombined sources1
Modified residuei344PhosphoserineCombined sources1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q86X02

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q86X02

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q86X02

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q86X02

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q86X02

PeptideAtlas

More...
PeptideAtlasi
Q86X02

PRoteomics IDEntifications database

More...
PRIDEi
Q86X02

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
70217

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q86X02

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q86X02

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000109089, Expressed in cerebellar hemisphere and 217 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q86X02, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q86X02, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000109089, Tissue enhanced (brain)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q86X02
With#Exp.IntAct
ANKRD11 [X5D778]3EBI-11063830,EBI-17183751
BFSP2 [Q13515]4EBI-11063830,EBI-10229433
C1orf216 [Q8TAB5]3EBI-11063830,EBI-747505
C4orf46 [Q504U0]8EBI-11063830,EBI-6657981
CCDC146 [Q8IYE0]3EBI-11063830,EBI-10749669
CCDC153 - isoform 2 [Q494R4-2]3EBI-11063830,EBI-11974185
CCDC185 [Q8N715]3EBI-11063830,EBI-740814
CCHCR1 - isoform 3 [Q8TD31-3]3EBI-11063830,EBI-10175300
CDR2 [Q01850]5EBI-11063830,EBI-1181367
itself4EBI-11063830,EBI-11063830
COX5B [P10606]3EBI-11063830,EBI-1053725
EHHADH [Q08426]3EBI-11063830,EBI-2339219
ELOA [Q14241]3EBI-11063830,EBI-742350
FAIM - isoform 2 [Q9NVQ4-2]6EBI-11063830,EBI-12039347
FAM161A [Q3B820]3EBI-11063830,EBI-719941
FAM161B [Q96MY7]3EBI-11063830,EBI-7225287
FAM86C1P - isoform 2 [Q9NVL1-2]3EBI-11063830,EBI-12845222
HDAC4 - isoform 2 [P56524-2]3EBI-11063830,EBI-11953488
HSF2BP [O75031]3EBI-11063830,EBI-7116203
INO80B [Q9C086]3EBI-11063830,EBI-715611
KRT31 [Q15323]3EBI-11063830,EBI-948001
KRTAP13-4 [Q3LI77]3EBI-11063830,EBI-11953996
LENG1 [Q96BZ8]3EBI-11063830,EBI-726510
MESD [Q14696]3EBI-11063830,EBI-6165891
MGC50722 [Q8IVT4]3EBI-11063830,EBI-14086479
OIP5 [O43482]3EBI-11063830,EBI-536879
PPP1R18 [Q6NYC8]3EBI-11063830,EBI-2557469
PRPF31 [Q8WWY3]3EBI-11063830,EBI-1567797
PSME3 [P61289]3EBI-11063830,EBI-355546
RASAL3 [Q86YV0]3EBI-11063830,EBI-3437896
RASD1 [Q9Y272]3EBI-11063830,EBI-740818
REL - isoform 2 [Q04864-2]3EBI-11063830,EBI-10829018
RINT1 [Q6NUQ1]3EBI-11063830,EBI-726876
SCNM1 [Q9BWG6]3EBI-11063830,EBI-748391
SH2D4A [Q9H788]3EBI-11063830,EBI-747035
SMRP1 [Q8NCR6]3EBI-11063830,EBI-10269322
SPRY1 [O43609]3EBI-11063830,EBI-3866665
STX11 [O75558]3EBI-11063830,EBI-714135
TBRG4 [Q969Z0]3EBI-11063830,EBI-702328
TCEANC - isoform 2 [Q8N8B7-2]3EBI-11063830,EBI-11955057
TCHP [Q9BT92]3EBI-11063830,EBI-740781
TCP10L [Q8TDR4]3EBI-11063830,EBI-3923210
TFIP11 [Q9UBB9]3EBI-11063830,EBI-1105213
TSGA10IP [Q3SY00]6EBI-11063830,EBI-10241197
UBE2I [Q7KZS0]3EBI-11063830,EBI-10180829
ZBTB42 [B2RXF5]3EBI-11063830,EBI-12287587
ZNF19 [P17023]3EBI-11063830,EBI-12884200
ZNF250 - isoform 3 [P15622-3]3EBI-11063830,EBI-10177272
ZNF35 [P13682]3EBI-11063830,EBI-11041653
ZNF417 [Q8TAU3]3EBI-11063830,EBI-740727
ZNF572 [Q7Z3I7]3EBI-11063830,EBI-10172590
ZNF629 [Q9UEG4]3EBI-11063830,EBI-9977294
ZNF648 [Q5T619]3EBI-11063830,EBI-11985915
ZNF655 [Q8N720]3EBI-11063830,EBI-625509
ZNF669 [Q96BR6]3EBI-11063830,EBI-12006574
ZNF688 [P0C7X2]3EBI-11063830,EBI-4395732
ZNF80 [P51504]3EBI-11063830,EBI-12013828
ZNF835 [Q9Y2P0]3EBI-11063830,EBI-5667516
ZSCAN22 [P10073]3EBI-11063830,EBI-10178224
ZSCAN23 [Q3MJ62]3EBI-11063830,EBI-5667532
ZSCAN26 [Q16670]3EBI-11063830,EBI-3920053

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
119060, 67 interactors

Protein interaction database and analysis system

More...
IntActi
Q86X02, 64 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000336587

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q86X02, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q86X02

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili38 – 143Sequence analysisAdd BLAST106
Coiled coili188 – 265Sequence analysisAdd BLAST78
Coiled coili350 – 377Sequence analysisAdd BLAST28

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CDR2 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QRN3, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000018570

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_048751_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q86X02

Identification of Orthologs from Complete Genome Data

More...
OMAi
RDFRGEG

Database of Orthologous Groups

More...
OrthoDBi
1101523at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q86X02

TreeFam database of animal gene trees

More...
TreeFami
TF326183

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026079, CDR2

The PANTHER Classification System

More...
PANTHERi
PTHR19232, PTHR19232, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q86X02-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRRAAGMEDF SAEEEESWYD QQDLEQDLHL AAELGKTLLE RNKELEGSLQ
60 70 80 90 100
QMYSTNEEQV QEIEYLTKQL DTLRHVNEQH AKVYEQLDLT ARDLELTNHR
110 120 130 140 150
LVLESKAAQQ KIHGLTETIE RLQAQVEELQ AQVEQLRGLE QLRVLREKRE
160 170 180 190 200
RRRTIHTFPC LKELCTSPRC KDAFRLHSSS LELGPRPLEQ ENERLQTLVG
210 220 230 240 250
ALRSQVSQER QRKERAEREY TAVLQEYSEL ERQLCEMEAC RLRVQELEAE
260 270 280 290 300
LLELQQMKQA KTYLLGPDDH LAEALLAPLT QAPEADDPQP GRGDDLGAQD
310 320 330 340 350
GVSSPAASPG HVVRKSCSDT ALNAIVAKDP ASRHAGNLTL HANSVRKRGM
360 370 380 390 400
SILREVDEQY HALLEKYEEL LSKCRQHGAG VRHAGVQTSR PISRDSSWRD
410 420 430 440 450
LRGGEEGQGE VKAGEKSLSQ HVEAVDKRLE QSQPEYKALF KEIFSRIQKT
460
KADINATKVK THSSK
Length:465
Mass (Da):53,010
Last modified:October 23, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE9231122B2378B71
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAA91850 differs from that shown. Reason: Frameshift.Curated
The sequence AAH47534 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti383H → D in AAA91850 (Ref. 1) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_035384300D → E. Corresponds to variant dbSNP:rs36057512Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
L02867 mRNA Translation: AAA91850.1 Frameshift.
AK294006 mRNA Translation: BAG57368.1
CH471099 Genomic DNA Translation: EAW89224.1
BC047534 mRNA Translation: AAH47534.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS11710.2

NCBI Reference Sequences

More...
RefSeqi
NP_055418.2, NM_014603.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000337231; ENSP00000336587; ENSG00000109089

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
30850

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:30850

UCSC genome browser

More...
UCSCi
uc002jml.5, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L02867 mRNA Translation: AAA91850.1 Frameshift.
AK294006 mRNA Translation: BAG57368.1
CH471099 Genomic DNA Translation: EAW89224.1
BC047534 mRNA Translation: AAH47534.1 Different initiation.
CCDSiCCDS11710.2
RefSeqiNP_055418.2, NM_014603.2

3D structure databases

SMRiQ86X02
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi119060, 67 interactors
IntActiQ86X02, 64 interactors
STRINGi9606.ENSP00000336587

PTM databases

iPTMnetiQ86X02
PhosphoSitePlusiQ86X02

Genetic variation databases

BioMutaiCDR2L
DMDMi160017566

Proteomic databases

EPDiQ86X02
jPOSTiQ86X02
MassIVEiQ86X02
MaxQBiQ86X02
PaxDbiQ86X02
PeptideAtlasiQ86X02
PRIDEiQ86X02
ProteomicsDBi70217

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
19492, 88 antibodies

The DNASU plasmid repository

More...
DNASUi
30850

Genome annotation databases

EnsembliENST00000337231; ENSP00000336587; ENSG00000109089
GeneIDi30850
KEGGihsa:30850
UCSCiuc002jml.5, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
30850
DisGeNETi30850

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CDR2L
HGNCiHGNC:29999, CDR2L
HPAiENSG00000109089, Tissue enhanced (brain)
neXtProtiNX_Q86X02
OpenTargetsiENSG00000109089
PharmGKBiPA142672137
VEuPathDBiHostDB:ENSG00000109089.7

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502QRN3, Eukaryota
GeneTreeiENSGT00390000018570
HOGENOMiCLU_048751_0_0_1
InParanoidiQ86X02
OMAiRDFRGEG
OrthoDBi1101523at2759
PhylomeDBiQ86X02
TreeFamiTF326183

Enzyme and pathway databases

PathwayCommonsiQ86X02

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
30850, 6 hits in 872 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CDR2L, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
30850
PharosiQ86X02, Tbio

Protein Ontology

More...
PROi
PR:Q86X02
RNActiQ86X02, protein

Gene expression databases

BgeeiENSG00000109089, Expressed in cerebellar hemisphere and 217 other tissues
ExpressionAtlasiQ86X02, baseline and differential
GenevisibleiQ86X02, HS

Family and domain databases

InterProiView protein in InterPro
IPR026079, CDR2
PANTHERiPTHR19232, PTHR19232, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCDR2L_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86X02
Secondary accession number(s): B4DFA7, Q15175
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: October 23, 2007
Last modified: February 10, 2021
This is version 117 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. SIMILARITY comments
    Index of protein domains and families
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