Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 101 (12 Aug 2020)
Sequence version 2 (20 Apr 2010)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Uncharacterized protein C17orf64

Gene

C17orf64

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q86WR6

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein C17orf64
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000141371.12

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26990, C17orf64

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q86WR6

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000141371

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142672247

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q86WR6, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
C17orf64

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002871741 – 236Uncharacterized protein C17orf64Add BLAST236

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q86WR6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q86WR6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q86WR6

PeptideAtlas

More...
PeptideAtlasi
Q86WR6

PRoteomics IDEntifications database

More...
PRIDEi
Q86WR6

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
70192

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q86WR6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q86WR6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000141371, Expressed in left testis and 91 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q86WR6, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q86WR6, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000141371, Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
125886, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000269127

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q86WR6, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q86WR6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0384, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000003769

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_095548_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q86WR6

Identification of Orthologs from Complete Genome Data

More...
OMAi
VPCLETS

Database of Orthologous Groups

More...
OrthoDBi
1232482at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q86WR6

TreeFam database of animal gene trees

More...
TreeFami
TF335849

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039880, C17orf64-like
IPR025260, DUF4208

The PANTHER Classification System

More...
PANTHERi
PTHR21765, PTHR21765, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13907, DUF4208, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01176, DUF4208, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q86WR6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEASDGQGGE GDKPLEQVTN VSCLETSSSA SPARDSLMRH AKGLDQDTFK
60 70 80 90 100
TCKEYLRPLK KFLRKLHLPR DLPQKKKLKY MKQSLVVLGD HINTFLQHYC
110 120 130 140 150
QAWEIKHWRK MLWRFISLFS ELEAKQLRRL YKYTKSSQPA KFLVTFCASD
160 170 180 190 200
APERSLLADR EDSLPKLCHA WGLHSNISGM KERLSNMQTP GQGSPLPGQP
210 220 230
RSQDHVKKDS LRELSQKPKL KRKRIKEAPE TPETEP
Length:236
Mass (Da):27,182
Last modified:April 20, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6C528E415783DDAC
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7EQ24K7EQ24_HUMAN
Uncharacterized protein C17orf64
C17orf64
98Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JLI9A0A0G2JLI9_HUMAN
Uncharacterized protein C17orf64
C17orf64
9Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH36356 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence AAH48806 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC037475 Genomic DNA No translation available.
BC036356 mRNA Translation: AAH36356.1 Different initiation.
BC048806 mRNA Translation: AAH48806.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS32698.2

NCBI Reference Sequences

More...
RefSeqi
NP_859058.2, NM_181707.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000269127; ENSP00000269127; ENSG00000141371

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
124773

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:124773

UCSC genome browser

More...
UCSCi
uc002iyq.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC037475 Genomic DNA No translation available.
BC036356 mRNA Translation: AAH36356.1 Different initiation.
BC048806 mRNA Translation: AAH48806.1 Different initiation.
CCDSiCCDS32698.2
RefSeqiNP_859058.2, NM_181707.2

3D structure databases

SMRiQ86WR6
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi125886, 1 interactor
STRINGi9606.ENSP00000269127

PTM databases

iPTMnetiQ86WR6
PhosphoSitePlusiQ86WR6

Polymorphism and mutation databases

BioMutaiC17orf64

Proteomic databases

jPOSTiQ86WR6
MassIVEiQ86WR6
PaxDbiQ86WR6
PeptideAtlasiQ86WR6
PRIDEiQ86WR6
ProteomicsDBi70192

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
45592, 85 antibodies

Genome annotation databases

EnsembliENST00000269127; ENSP00000269127; ENSG00000141371
GeneIDi124773
KEGGihsa:124773
UCSCiuc002iyq.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
124773
EuPathDBiHostDB:ENSG00000141371.12

GeneCards: human genes, protein and diseases

More...
GeneCardsi
C17orf64
HGNCiHGNC:26990, C17orf64
HPAiENSG00000141371, Tissue enriched (testis)
neXtProtiNX_Q86WR6
OpenTargetsiENSG00000141371
PharmGKBiPA142672247

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0384, Eukaryota
GeneTreeiENSGT00390000003769
HOGENOMiCLU_095548_0_0_1
InParanoidiQ86WR6
OMAiVPCLETS
OrthoDBi1232482at2759
PhylomeDBiQ86WR6
TreeFamiTF335849

Enzyme and pathway databases

PathwayCommonsiQ86WR6

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
124773, 0 hits in 860 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
124773
PharosiQ86WR6, Tdark

Protein Ontology

More...
PROi
PR:Q86WR6
RNActiQ86WR6, protein

Gene expression databases

BgeeiENSG00000141371, Expressed in left testis and 91 other tissues
ExpressionAtlasiQ86WR6, baseline and differential
GenevisibleiQ86WR6, HS

Family and domain databases

InterProiView protein in InterPro
IPR039880, C17orf64-like
IPR025260, DUF4208
PANTHERiPTHR21765, PTHR21765, 1 hit
PfamiView protein in Pfam
PF13907, DUF4208, 1 hit
SMARTiView protein in SMART
SM01176, DUF4208, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCQ064_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86WR6
Secondary accession number(s): Q8IY87
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: April 20, 2010
Last modified: August 12, 2020
This is version 101 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again