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Entry version 128 (16 Oct 2019)
Sequence version 2 (26 Feb 2008)
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Protein

Sodium-independent sulfate anion transporter

Gene

SLC26A11

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC).1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAnion exchange, Ion transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-427601 Multifunctional anion exchangers

Protein family/group databases

Transport Classification Database

More...
TCDBi
2.A.53.1.10 the sulfate permease (sulp) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sodium-independent sulfate anion transporter
Alternative name(s):
Solute carrier family 26 member 11
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SLC26A11Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:14471 SLC26A11

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
610117 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q86WA9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 51ExtracellularSequence analysisAdd BLAST51
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei52 – 72HelicalSequence analysisAdd BLAST21
Topological domaini73CytoplasmicSequence analysis1
Transmembranei74 – 94HelicalSequence analysisAdd BLAST21
Topological domaini95 – 100ExtracellularSequence analysis6
Transmembranei101 – 117HelicalSequence analysisAdd BLAST17
Topological domaini118 – 119CytoplasmicSequence analysis2
Transmembranei120 – 140HelicalSequence analysisAdd BLAST21
Topological domaini141 – 147ExtracellularSequence analysis7
Transmembranei148 – 168HelicalSequence analysisAdd BLAST21
Topological domaini169 – 197CytoplasmicSequence analysisAdd BLAST29
Transmembranei198 – 218HelicalSequence analysisAdd BLAST21
Topological domaini219 – 250ExtracellularSequence analysisAdd BLAST32
Transmembranei251 – 271HelicalSequence analysisAdd BLAST21
Topological domaini272 – 307CytoplasmicSequence analysisAdd BLAST36
Transmembranei308 – 328HelicalSequence analysisAdd BLAST21
Topological domaini329 – 341ExtracellularSequence analysisAdd BLAST13
Transmembranei342 – 362HelicalSequence analysisAdd BLAST21
Topological domaini363 – 374CytoplasmicSequence analysisAdd BLAST12
Transmembranei375 – 395HelicalSequence analysisAdd BLAST21
Topological domaini396 – 398ExtracellularSequence analysis3
Transmembranei399 – 419HelicalSequence analysisAdd BLAST21
Topological domaini420 – 441CytoplasmicSequence analysisAdd BLAST22
Transmembranei442 – 462HelicalSequence analysisAdd BLAST21
Topological domaini463 – 606ExtracellularSequence analysisAdd BLAST144

Keywords - Cellular componenti

Cell membrane, Lysosome, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000181045

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA37888

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q86WA9

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SLC26A11

Domain mapping of disease mutations (DMDM)

More...
DMDMi
182705284

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003206861 – 606Sodium-independent sulfate anion transporterAdd BLAST606

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q86WA9

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q86WA9

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q86WA9

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q86WA9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q86WA9

PeptideAtlas

More...
PeptideAtlasi
Q86WA9

PRoteomics IDEntifications database

More...
PRIDEi
Q86WA9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
70139

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q86WA9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q86WA9

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q86WA9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in all tissues tested with highest expression observed in brain, kidney, HEVEC and placenta and lowest in pancreas, skeletal muscle, liver, lung and heart.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000181045 Expressed in 189 organ(s), highest expression level in left lobe of thyroid gland

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q86WA9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q86WA9 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA029893

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
129771, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q86WA9, 2 interactors

Molecular INTeraction database

More...
MINTi
Q86WA9

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000355384

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini470 – 584STASPROSITE-ProRule annotationAdd BLAST115

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0236 Eukaryota
COG0659 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183057

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q86WA9

KEGG Orthology (KO)

More...
KOi
K14708

Identification of Orthologs from Complete Genome Data

More...
OMAi
CELRVSN

Database of Orthologous Groups

More...
OrthoDBi
289441at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q86WA9

TreeFam database of animal gene trees

More...
TreeFami
TF323537

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.750.24, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018045 S04_transporter_CS
IPR011547 SLC26A/SulP_dom
IPR001902 SLC26A/SulP_fam
IPR002645 STAS_dom
IPR036513 STAS_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR11814 PTHR11814, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01740 STAS, 1 hit
PF00916 Sulfate_transp, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52091 SSF52091, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01130 SLC26A, 1 hit
PS50801 STAS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

Q86WA9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPSSVTALGQ ARSSGPGMAP SACCCSPAAL QRRLPILAWL PSYSLQWLKM
60 70 80 90 100
DFVAGLSVGL TAIPQALAYA EVAGLPPQYG LYSAFMGCFV YFFLGTSRDV
110 120 130 140 150
TLGPTAIMSL LVSFYTFHEP AYAVLLAFLS GCIQLAMGVL RLGFLLDFIS
160 170 180 190 200
YPVIKGFTSA AAVTIGFGQI KNLLGLQNIP RPFFLQVYHT FLRIAETRVG
210 220 230 240 250
DAVLGLVCML LLLVLKLMRD HVPPVHPEMP PGVRLSRGLV WAATTARNAL
260 270 280 290 300
VVSFAALVAY SFEVTGYQPF ILTGETAEGL PPVRIPPFSV TTANGTISFT
310 320 330 340 350
EMVQDMGAGL AVVPLMGLLE SIAVAKAFAS QNNYRIDANQ ELLAIGLTNM
360 370 380 390 400
LGSLVSSYPV TGSFGRTAVN AQSGVCTPAG GLVTGVLVLL SLDYLTSLFY
410 420 430 440 450
YIPKSALAAV IIMAVAPLFD TKIFRTLWRV KRLDLLPLCV TFLLCFWEVQ
460 470 480 490 500
YGILAGALVS LLMLLHSAAR PETKVSEGPV LVLQPASGLS FPAMEALREE
510 520 530 540 550
ILSRALEVSP PRCLVLECTH VCSIDYTVVL GLGELLQDFQ KQGVALAFVG
560 570 580 590 600
LQVPVLRVLL SADLKGFQYF STLEEAEKHL RQEPGTQPYN IREDSILDQK

VALLKA
Length:606
Mass (Da):65,299
Last modified:February 26, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA0D974B49F16450D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
I3L1H1I3L1H1_HUMAN
Sodium-independent sulfate anion tr...
SLC26A11
210Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L124I3L124_HUMAN
Sodium-independent sulfate anion tr...
SLC26A11
153Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L2J9I3L2J9_HUMAN
Sodium-independent sulfate anion tr...
SLC26A11
64Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L266I3L266_HUMAN
Sodium-independent sulfate anion tr...
SLC26A11
133Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L3K8I3L3K8_HUMAN
Sodium-independent sulfate anion tr...
SLC26A11
77Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L0N9I3L0N9_HUMAN
Sodium-independent sulfate anion tr...
SLC26A11
197Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L250I3L250_HUMAN
Sodium-independent sulfate anion tr...
SLC26A11
58Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti14S → Y in CAD66450 (PubMed:12626430).Curated1
Sequence conflicti319L → M in CAD66450 (PubMed:12626430).Curated1
Sequence conflicti324V → M in AAM92902 (PubMed:11087667).Curated1
Sequence conflicti328F → S in AAO26673 (Ref. 2) Curated1
Sequence conflicti332N → D in CAD66450 (PubMed:12626430).Curated1
Sequence conflicti415V → A in AAO26673 (Ref. 2) Curated1
Sequence conflicti569Y → H in AAO26673 (Ref. 2) Curated1
Sequence conflicti579H → R in BAC11496 (PubMed:16303743).Curated1
Sequence conflicti583E → K in AAH35900 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_068239122Y → C1 PublicationCorresponds to variant dbSNP:rs765188926Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ544073 mRNA Translation: CAD66450.1
AF345195 mRNA Translation: AAO26673.1
AK315132 mRNA Translation: BAG37584.1
AK075248 mRNA Translation: BAC11496.1
BC035900 mRNA Translation: AAH35900.2
BC047451 mRNA Translation: AAH47451.1
AF331524 mRNA Translation: AAM92902.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS11771.2

NCBI Reference Sequences

More...
RefSeqi
NP_001159819.1, NM_001166347.1
NP_001159820.1, NM_001166348.1
NP_001159821.1, NM_001166349.1
NP_775897.3, NM_173626.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000361193; ENSP00000355384; ENSG00000181045
ENST00000411502; ENSP00000403998; ENSG00000181045
ENST00000546047; ENSP00000440724; ENSG00000181045
ENST00000572725; ENSP00000459470; ENSG00000181045

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
284129

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:284129

UCSC genome browser

More...
UCSCi
uc002jyb.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ544073 mRNA Translation: CAD66450.1
AF345195 mRNA Translation: AAO26673.1
AK315132 mRNA Translation: BAG37584.1
AK075248 mRNA Translation: BAC11496.1
BC035900 mRNA Translation: AAH35900.2
BC047451 mRNA Translation: AAH47451.1
AF331524 mRNA Translation: AAM92902.1
CCDSiCCDS11771.2
RefSeqiNP_001159819.1, NM_001166347.1
NP_001159820.1, NM_001166348.1
NP_001159821.1, NM_001166349.1
NP_775897.3, NM_173626.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi129771, 1 interactor
IntActiQ86WA9, 2 interactors
MINTiQ86WA9
STRINGi9606.ENSP00000355384

Protein family/group databases

TCDBi2.A.53.1.10 the sulfate permease (sulp) family

PTM databases

iPTMnetiQ86WA9
PhosphoSitePlusiQ86WA9
SwissPalmiQ86WA9

Polymorphism and mutation databases

BioMutaiSLC26A11
DMDMi182705284

Proteomic databases

EPDiQ86WA9
jPOSTiQ86WA9
MassIVEiQ86WA9
MaxQBiQ86WA9
PaxDbiQ86WA9
PeptideAtlasiQ86WA9
PRIDEiQ86WA9
ProteomicsDBi70139

Genome annotation databases

EnsembliENST00000361193; ENSP00000355384; ENSG00000181045
ENST00000411502; ENSP00000403998; ENSG00000181045
ENST00000546047; ENSP00000440724; ENSG00000181045
ENST00000572725; ENSP00000459470; ENSG00000181045
GeneIDi284129
KEGGihsa:284129
UCSCiuc002jyb.3 human

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
284129

GeneCards: human genes, protein and diseases

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GeneCardsi
SLC26A11
HGNCiHGNC:14471 SLC26A11
HPAiHPA029893
MIMi610117 gene
neXtProtiNX_Q86WA9
OpenTargetsiENSG00000181045
PharmGKBiPA37888

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG0236 Eukaryota
COG0659 LUCA
GeneTreeiENSGT00950000183057
InParanoidiQ86WA9
KOiK14708
OMAiCELRVSN
OrthoDBi289441at2759
PhylomeDBiQ86WA9
TreeFamiTF323537

Enzyme and pathway databases

ReactomeiR-HSA-427601 Multifunctional anion exchangers

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
SLC26A11 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
284129
PharosiQ86WA9

Protein Ontology

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PROi
PR:Q86WA9

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000181045 Expressed in 189 organ(s), highest expression level in left lobe of thyroid gland
ExpressionAtlasiQ86WA9 baseline and differential
GenevisibleiQ86WA9 HS

Family and domain databases

Gene3Di3.30.750.24, 1 hit
InterProiView protein in InterPro
IPR018045 S04_transporter_CS
IPR011547 SLC26A/SulP_dom
IPR001902 SLC26A/SulP_fam
IPR002645 STAS_dom
IPR036513 STAS_dom_sf
PANTHERiPTHR11814 PTHR11814, 1 hit
PfamiView protein in Pfam
PF01740 STAS, 1 hit
PF00916 Sulfate_transp, 1 hit
SUPFAMiSSF52091 SSF52091, 1 hit
PROSITEiView protein in PROSITE
PS01130 SLC26A, 1 hit
PS50801 STAS, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS2611_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86WA9
Secondary accession number(s): B2RCI7
, Q86VX1, Q86YX7, Q8IV11, Q8N2I1, Q8NG03
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 26, 2008
Last modified: October 16, 2019
This is version 128 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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