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Protein

Protein FAM228A

Gene

FAM228A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM228A
Gene namesi
Name:FAM228A
Synonyms:C2orf84
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000186453.12
HGNCiHGNC:34418 FAM228A
neXtProtiNX_Q86W67

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000186453
PharmGKBiPA164717160

Polymorphism and mutation databases

BioMutaiFAM228A

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003484451 – 206Protein FAM228AAdd BLAST206

Proteomic databases

EPDiQ86W67
PaxDbiQ86W67
PeptideAtlasiQ86W67
PRIDEiQ86W67
ProteomicsDBi70125

PTM databases

iPTMnetiQ86W67
PhosphoSitePlusiQ86W67

Expressioni

Gene expression databases

BgeeiENSG00000186453 Expressed in 82 organ(s), highest expression level in right testis
ExpressionAtlasiQ86W67 baseline and differential
GenevisibleiQ86W67 HS

Interactioni

Protein-protein interaction databases

BioGridi575555, 1 interactor
IntActiQ86W67, 17 interactors
STRINGi9606.ENSP00000295150

Structurei

3D structure databases

ProteinModelPortaliQ86W67
SMRiQ86W67
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM228 family.Curated

Phylogenomic databases

eggNOGiENOG410IXI0 Eukaryota
ENOG41116AT LUCA
GeneTreeiENSGT00530000064185
HOGENOMiHOG000111340
InParanoidiQ86W67
PhylomeDBiQ86W67
TreeFamiTF336288

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q86W67-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAATKTASYD EHFRPEKLRE WPEPESVSLM EVLAREDIDE AVCAILFKEN
60 70 80 90 100
SIVKVTVPPF VDPLFQRQQE VDEERRTGLQ CETGKRHSIK ELEEIEKARL
110 120 130 140 150
HASSPYFTFT SHCVIPKEWH KASARARSKT YKYSPEKLIY ADKKQKRKEK
160 170 180 190 200
KTADLSQAAF ERQFLSSKLS QKNKVGERKG LVSRGLGRGW HAGLCSTHEQ

HILVPE
Length:206
Mass (Da):23,752
Last modified:June 1, 2003 - v1
Checksum:iDC057FFD707AA688
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H7C3M9H7C3M9_HUMAN
Protein FAM228A
FAM228A
210Annotation score:
H7C4B8H7C4B8_HUMAN
Protein FAM228A
FAM228A
136Annotation score:
F2Z3J0F2Z3J0_HUMAN
Protein FAM228A
FAM228A
106Annotation score:

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_046178140Y → C. Corresponds to variant dbSNP:rs2288073Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008073 Genomic DNA Translation: AAY14667.1
CH471053 Genomic DNA Translation: EAX00756.1
BC050462 mRNA Translation: AAH50462.1
CCDSiCCDS42659.1
RefSeqiNP_001035800.1, NM_001040710.2
UniGeneiHs.741736

Genome annotation databases

EnsembliENST00000295150; ENSP00000295150; ENSG00000186453
GeneIDi653140
KEGGihsa:653140
UCSCiuc002rfc.3 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008073 Genomic DNA Translation: AAY14667.1
CH471053 Genomic DNA Translation: EAX00756.1
BC050462 mRNA Translation: AAH50462.1
CCDSiCCDS42659.1
RefSeqiNP_001035800.1, NM_001040710.2
UniGeneiHs.741736

3D structure databases

ProteinModelPortaliQ86W67
SMRiQ86W67
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi575555, 1 interactor
IntActiQ86W67, 17 interactors
STRINGi9606.ENSP00000295150

PTM databases

iPTMnetiQ86W67
PhosphoSitePlusiQ86W67

Polymorphism and mutation databases

BioMutaiFAM228A

Proteomic databases

EPDiQ86W67
PaxDbiQ86W67
PeptideAtlasiQ86W67
PRIDEiQ86W67
ProteomicsDBi70125

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000295150; ENSP00000295150; ENSG00000186453
GeneIDi653140
KEGGihsa:653140
UCSCiuc002rfc.3 human

Organism-specific databases

CTDi653140
EuPathDBiHostDB:ENSG00000186453.12
GeneCardsiFAM228A
HGNCiHGNC:34418 FAM228A
neXtProtiNX_Q86W67
OpenTargetsiENSG00000186453
PharmGKBiPA164717160
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IXI0 Eukaryota
ENOG41116AT LUCA
GeneTreeiENSGT00530000064185
HOGENOMiHOG000111340
InParanoidiQ86W67
PhylomeDBiQ86W67
TreeFamiTF336288

Miscellaneous databases

ChiTaRSiFAM228A human
GenomeRNAii653140
PROiPR:Q86W67

Gene expression databases

BgeeiENSG00000186453 Expressed in 82 organ(s), highest expression level in right testis
ExpressionAtlasiQ86W67 baseline and differential
GenevisibleiQ86W67 HS

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiF228A_HUMAN
AccessioniPrimary (citable) accession number: Q86W67
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: June 1, 2003
Last modified: September 12, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. SIMILARITY comments
    Index of protein domains and families
  4. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  5. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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