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Entry version 137 (08 May 2019)
Sequence version 2 (17 Apr 2007)
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Protein

NACHT, LRR and PYD domains-containing protein 13

Gene

NLRP13

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in inflammation.Curated

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi235 – 242ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
NACHT, LRR and PYD domains-containing protein 13
Alternative name(s):
Nucleotide-binding oligomerization domain protein 14
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NLRP13
Synonyms:NALP13, NOD14
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:22937 NLRP13

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
609660 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q86W25

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000173572

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162397891

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
NLRP13

Domain mapping of disease mutations (DMDM)

More...
DMDMi
145559500

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000809001 – 1043NACHT, LRR and PYD domains-containing protein 13Add BLAST1043

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q86W25

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q86W25

PeptideAtlas

More...
PeptideAtlasi
Q86W25

PRoteomics IDEntifications database

More...
PRIDEi
Q86W25

ProteomicsDB human proteome resource

More...
ProteomicsDBi
70104

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q86W25

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q86W25

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000173572 Expressed in 9 organ(s), highest expression level in oocyte

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q86W25 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q86W25 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA060459

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
125963, 2 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000343891

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 107PyrinPROSITE-ProRule annotationAdd BLAST107
Domaini229 – 558NACHTPROSITE-ProRule annotationAdd BLAST330
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati725 – 749LRR 1Add BLAST25
Repeati781 – 804LRR 2Add BLAST24
Repeati837 – 864LRR 3Add BLAST28
Repeati894 – 917LRR 4Add BLAST24
Repeati923 – 946LRR 5Add BLAST24
Repeati951 – 978LRR 6Add BLAST28
Repeati1007 – 1030LRR 7Add BLAST24

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the NLRP family.Curated

Keywords - Domaini

Leucine-rich repeat, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410JA4D Eukaryota
ENOG411152B LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163591

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000294064

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q86W25

KEGG Orthology (KO)

More...
KOi
K22665

Identification of Orthologs from Complete Genome Data

More...
OMAi
LELWFCQ

Database of Orthologous Groups

More...
OrthoDBi
114368at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q86W25

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.80.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004020 DAPIN
IPR011029 DEATH-like_dom_sf
IPR001611 Leu-rich_rpt
IPR032675 LRR_dom_sf
IPR007111 NACHT_NTPase
IPR041267 NLRC_HD2
IPR041075 NOD2_WH
IPR027417 P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13516 LRR_6, 4 hits
PF05729 NACHT, 1 hit
PF17776 NLRC4_HD2, 1 hit
PF17779 NOD2_WH, 1 hit
PF02758 PYRIN, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01289 PYRIN, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47986 SSF47986, 1 hit
SSF52540 SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50824 DAPIN, 1 hit
PS50837 NACHT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q86W25-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNFSVITCPN GGTNQGLLPY LMALDQYQLE EFKLCLEPQQ LMDFWSAPQG
60 70 80 90 100
HFPRIPWANL RAADPLNLSF LLDEHFPKGQ AWKVVLGIFQ TMNLTSLCEK
110 120 130 140 150
VRAEMKENVQ TQELQDPTQE DLEMLEAAAG NMQTQGCQDP NQEELDELEE
160 170 180 190 200
ETGNVQAQGC QDPNQEEPEM LEEADHRRKY RENMKAELLE TWDNISWPKD
210 220 230 240 250
HVYIRNTSKD EHEELQRLLD PNRTRAQAQT IVLVGRAGVG KTTLAMQAML
260 270 280 290 300
HWANGVLFQQ RFSYVFYLSC HKIRYMKETT FAELISLDWP DFDAPIEEFM
310 320 330 340 350
SQPEKLLFII DGFEEIIISE SRSESLDDGS PCTDWYQELP VTKILHSLLK
360 370 380 390 400
KELVPLATLL ITIKTWFVRD LKASLVNPCF VQITGFTGDD LRVYFMRHFD
410 420 430 440 450
DSSEVEKILQ QLRKNETLFH SCSAPMVCWT VCSCLKQPKV RYYDLQSITQ
460 470 480 490 500
TTTSLYAYFF SNLFSTAEVD LADDSWPGQW RALCSLAIEG LWSMNFTFNK
510 520 530 540 550
EDTEIEGLEV PFIDSLYEFN ILQKINDCGG CTTFTHLSFQ EFFAAMSFVL
560 570 580 590 600
EEPREFPPHS TKPQEMKMLL QHVLLDKEAY WTPVVLFFFG LLNKNIAREL
610 620 630 640 650
EDTLHCKISP RVMEELLKWG EELGKAESAS LQFHILRLFH CLHESQEEDF
660 670 680 690 700
TKKMLGRIFE VDLNILEDEE LQASSFCLKH CKRLNKLRLS VSSHILERDL
710 720 730 740 750
EILETSKFDS RMHAWNSICS TLVTNENLHE LDLSNSKLHA SSVKGLCLAL
760 770 780 790 800
KNPRCKVQKL TCKSVTPEWV LQDLIIALQG NSKLTHLNFS SNKLGMTVPL
810 820 830 840 850
ILKALRHSAC NLKYLCLEKC NLSAASCQDL ALFLTSIQHV TRLCLGFNRL
860 870 880 890 900
QDDGIKLLCA ALTHPKCALE RLELWFCQLA APACKHLSDA LLQNRSLTHL
910 920 930 940 950
NLSKNSLRDE GVKFLCEALG RPDGNLQSLN LSGCSFTREG CGELANALSH
960 970 980 990 1000
NHNVKILDLG ENDLQDDGVK LLCEALKPHR ALHTLGLAKC NLTTACCQHL
1010 1020 1030 1040
FSVLSSSKSL VNLNLLGNEL DTDGVKMLCK ALKKSTCRLQ KLG
Length:1,043
Mass (Da):118,884
Last modified:April 17, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD2BAE6D83ACCA112
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0C4DGQ4A0A0C4DGQ4_HUMAN
NACHT, LRR and PYD domains-containi...
NLRP13
1,036Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti1030 – 1043KALKK…LQKLG → FKKTCTM in DAA01241 (PubMed:12766759).CuratedAdd BLAST14

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_031707247Q → R1 PublicationCorresponds to variant dbSNP:rs303997Ensembl.1
Natural variantiVAR_031708781N → S. Corresponds to variant dbSNP:rs17711239Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY154468 mRNA Translation: AAO18164.1
BK001108 mRNA Translation: DAA01241.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS33119.1

NCBI Reference Sequences

More...
RefSeqi
NP_001307986.1, NM_001321057.1
NP_789780.2, NM_176810.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000342929; ENSP00000343891; ENSG00000173572

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
126204

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:126204

UCSC genome browser

More...
UCSCi
uc010ygg.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY154468 mRNA Translation: AAO18164.1
BK001108 mRNA Translation: DAA01241.1
CCDSiCCDS33119.1
RefSeqiNP_001307986.1, NM_001321057.1
NP_789780.2, NM_176810.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi125963, 2 interactors
STRINGi9606.ENSP00000343891

PTM databases

iPTMnetiQ86W25
PhosphoSitePlusiQ86W25

Polymorphism and mutation databases

BioMutaiNLRP13
DMDMi145559500

Proteomic databases

jPOSTiQ86W25
PaxDbiQ86W25
PeptideAtlasiQ86W25
PRIDEiQ86W25
ProteomicsDBi70104

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
126204
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000342929; ENSP00000343891; ENSG00000173572
GeneIDi126204
KEGGihsa:126204
UCSCiuc010ygg.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
126204

GeneCards: human genes, protein and diseases

More...
GeneCardsi
NLRP13

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0040054
HGNCiHGNC:22937 NLRP13
HPAiHPA060459
MIMi609660 gene
neXtProtiNX_Q86W25
OpenTargetsiENSG00000173572
PharmGKBiPA162397891

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410JA4D Eukaryota
ENOG411152B LUCA
GeneTreeiENSGT00940000163591
HOGENOMiHOG000294064
InParanoidiQ86W25
KOiK22665
OMAiLELWFCQ
OrthoDBi114368at2759
PhylomeDBiQ86W25

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
NLRP13 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
NLRP13

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
126204

Protein Ontology

More...
PROi
PR:Q86W25

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000173572 Expressed in 9 organ(s), highest expression level in oocyte
ExpressionAtlasiQ86W25 baseline and differential
GenevisibleiQ86W25 HS

Family and domain databases

Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR004020 DAPIN
IPR011029 DEATH-like_dom_sf
IPR001611 Leu-rich_rpt
IPR032675 LRR_dom_sf
IPR007111 NACHT_NTPase
IPR041267 NLRC_HD2
IPR041075 NOD2_WH
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF13516 LRR_6, 4 hits
PF05729 NACHT, 1 hit
PF17776 NLRC4_HD2, 1 hit
PF17779 NOD2_WH, 1 hit
PF02758 PYRIN, 1 hit
SMARTiView protein in SMART
SM01289 PYRIN, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50824 DAPIN, 1 hit
PS50837 NACHT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNAL13_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86W25
Secondary accession number(s): Q7RTR5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: April 17, 2007
Last modified: May 8, 2019
This is version 137 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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