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Entry version 122 (13 Feb 2019)
Sequence version 3 (28 Mar 2018)
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Protein

Vacuolar fusion protein MON1 homolog A

Gene

MON1A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (By similarity). Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form (PubMed:23084991).By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • guanyl-nucleotide exchange factor activity Source: UniProtKB

GO - Biological processi

  • protein secretion Source: GO_Central

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGuanine-nucleotide releasing factor

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-8876198 RAB GEFs exchange GTP for GDP on RABs

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Vacuolar fusion protein MON1 homolog A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MON1A
Synonyms:SAND1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000164077.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:28207 MON1A

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
611464 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q86VX9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
84315

Open Targets

More...
OpenTargetsi
ENSG00000164077

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142671340

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MON1A

Domain mapping of disease mutations (DMDM)

More...
DMDMi
146324996

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002857611 – 652Vacuolar fusion protein MON1 homolog AAdd BLAST652

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei128PhosphoserineCombined sources1
Modified residuei153PhosphoserineBy similarity1
Modified residuei158PhosphothreonineCombined sources1
Modified residuei188PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q86VX9

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q86VX9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q86VX9

PeptideAtlas

More...
PeptideAtlasi
Q86VX9

PRoteomics IDEntifications database

More...
PRIDEi
Q86VX9

ProteomicsDB human proteome resource

More...
ProteomicsDBi
70086
70087 [Q86VX9-2]
70088 [Q86VX9-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q86VX9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q86VX9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000164077 Expressed in 172 organ(s), highest expression level in quadriceps femoris

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q86VX9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q86VX9 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA053752
HPA058032

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with CCZ1 (PubMed:23084991). Found in a complex with RMC1, CCZ1, MON1A and MON1B (PubMed:29038162).2 Publications

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
124041, 9 interactors

Protein interaction database and analysis system

More...
IntActi
Q86VX9, 8 interactors

Molecular INTeraction database

More...
MINTi
Q86VX9

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000296473

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q86VX9

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q86VX9

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MON1/SAND family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0997 Eukaryota
ENOG410XR29 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000006665

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000031337

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG064381

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q86VX9

KEGG Orthology (KO)

More...
KOi
K20195

Identification of Orthologs from Complete Genome Data

More...
OMAi
TQLNHIF

Database of Orthologous Groups

More...
OrthoDBi
829786at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q86VX9

TreeFam database of animal gene trees

More...
TreeFami
TF314665

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004353 Mon1

The PANTHER Classification System

More...
PANTHERi
PTHR13027 PTHR13027, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03164 Mon1, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01546 YEAST73DUF

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (5+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 5 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 5 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q86VX9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MHPGGGPSRA ERLELGLGRE RPAKAIFLHR RPGEGGGRER CLRCGHVCVR
60 70 80 90 100
RGPGPREAVP SGRPRPDTLT PPWVRQRAVT GTFCASWTPL RNRRAQRMAT
110 120 130 140 150
DMQRKRSSEC LDGTLTPSDG QSMERAESPT PGMAQGMEPG AGQEGAMFVH
160 170 180 190 200
ARSYEDLTES EDGAASGDSH KEGTRGPPPL PTDMRQISQD FSELSTQLTG
210 220 230 240 250
VARDLQEEML PGSSEDWLEP PGAVGRPATE PPREGTTEGD EEDATEAWRL
260 270 280 290 300
HQKHVFVLSE AGKPVYSRYG SEEALSSTMG VMVALVSFLE ADKNAIRSIH
310 320 330 340 350
ADGYKVVFVR RSPLVLVAVA RTRQSAQELA QELLYIYYQI LSLLTGAQLS
360 370 380 390 400
HIFQQKQNYD LRRLLSGSER ITDNLLQLMA RDPSFLMGAA RCLPLAAAVR
410 420 430 440 450
DTVSASLQQA RARSLVFSIL LARNQLVALV RRKDQFLHPI DLHLLFNLIS
460 470 480 490 500
SSSSFREGEA WTPVCLPKFN AAGFFHAHIS YLEPDTDLCL LLVSTDREDF
510 520 530 540 550
FAVSDCRRRF QERLRKRGAH LALREALRTP YYSVAQVGIP DLRHFLYKSK
560 570 580 590 600
SSGLFTSPEI EAPYTSEEEQ ERLLGLYQYL HSRAHNASRP LKTIYYTGPN
610 620 630 640 650
ENLLAWVTGA FELYMCYSPL GTKASAVSAI HKLMRWIRKE EDRLFILTPL

TY
Note: No experimental confirmation available. Gene prediction based on EST data.
Length:652
Mass (Da):72,895
Last modified:March 28, 2018 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i344D326577E66FE2
GO
Isoform 2 (identifier: Q86VX9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-97: Missing.
     140-301: Missing.

Show »
Length:393
Mass (Da):44,692
Checksum:i08CD3CF132D5B963
GO
Isoform 3 (identifier: Q86VX9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-97: Missing.
     140-301: Missing.
     557-557: S → R
     558-652: Missing.

Show »
Length:298
Mass (Da):33,713
Checksum:i2B1C495E32796DC9
GO
Isoform 4 (identifier: Q86VX9-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     140-301: Missing.

Note: No experimental confirmation available. Gene prediction based on EST data.
Show »
Length:490
Mass (Da):55,456
Checksum:i1402A856E41AC982
GO
Isoform 5 (identifier: Q86VX9-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-97: Missing.

Show »
Length:555
Mass (Da):62,131
Checksum:i3428BEBFD9EA1626
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0A0MSQ9A0A0A0MSQ9_HUMAN
Vacuolar fusion protein MON1 homolo...
MON1A
563Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH47022 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0594301 – 97Missing in isoform 5, isoform 2 and isoform 3. 2 PublicationsAdd BLAST97
Alternative sequenceiVSP_059431140 – 301Missing in isoform 2, isoform 3 and isoform 4. 2 PublicationsAdd BLAST162
Alternative sequenceiVSP_059432557S → R in isoform 3. 1 Publication1
Alternative sequenceiVSP_059433558 – 652Missing in isoform 3. 1 PublicationAdd BLAST95

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK092018 mRNA Translation: BAC03790.1
AK315630 mRNA Translation: BAG37998.1
AC105935 Genomic DNA No translation available.
CH471055 Genomic DNA Translation: EAW65037.1
CH471055 Genomic DNA Translation: EAW65038.1
BC006299 mRNA Translation: AAH06299.1
BC009459 mRNA Translation: AAH09459.1
BC047022 mRNA Translation: AAH47022.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS2808.2 [Q86VX9-1]
CCDS46830.1 [Q86VX9-4]

NCBI Reference Sequences

More...
RefSeqi
NP_001135973.1, NM_001142501.1 [Q86VX9-4]
NP_115731.2, NM_032355.3 [Q86VX9-1]
XP_006713408.1, XM_006713345.3 [Q86VX9-5]
XP_011532462.1, XM_011534160.1 [Q86VX9-5]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.655014

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000296473; ENSP00000296473; ENSG00000164077 [Q86VX9-1]
ENST00000455683; ENSP00000404793; ENSG00000164077 [Q86VX9-4]
ENST00000642691; ENSP00000494294; ENSG00000164077 [Q86VX9-5]
ENST00000645862; ENSP00000494452; ENSG00000164077 [Q86VX9-5]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
84315

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:84315

UCSC genome browser

More...
UCSCi
uc003cxz.4 human
uc003cya.4 human [Q86VX9-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK092018 mRNA Translation: BAC03790.1
AK315630 mRNA Translation: BAG37998.1
AC105935 Genomic DNA No translation available.
CH471055 Genomic DNA Translation: EAW65037.1
CH471055 Genomic DNA Translation: EAW65038.1
BC006299 mRNA Translation: AAH06299.1
BC009459 mRNA Translation: AAH09459.1
BC047022 mRNA Translation: AAH47022.1 Different initiation.
CCDSiCCDS2808.2 [Q86VX9-1]
CCDS46830.1 [Q86VX9-4]
RefSeqiNP_001135973.1, NM_001142501.1 [Q86VX9-4]
NP_115731.2, NM_032355.3 [Q86VX9-1]
XP_006713408.1, XM_006713345.3 [Q86VX9-5]
XP_011532462.1, XM_011534160.1 [Q86VX9-5]
UniGeneiHs.655014

3D structure databases

ProteinModelPortaliQ86VX9
SMRiQ86VX9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi124041, 9 interactors
IntActiQ86VX9, 8 interactors
MINTiQ86VX9
STRINGi9606.ENSP00000296473

PTM databases

iPTMnetiQ86VX9
PhosphoSitePlusiQ86VX9

Polymorphism and mutation databases

BioMutaiMON1A
DMDMi146324996

Proteomic databases

EPDiQ86VX9
jPOSTiQ86VX9
PaxDbiQ86VX9
PeptideAtlasiQ86VX9
PRIDEiQ86VX9
ProteomicsDBi70086
70087 [Q86VX9-2]
70088 [Q86VX9-3]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
84315
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000296473; ENSP00000296473; ENSG00000164077 [Q86VX9-1]
ENST00000455683; ENSP00000404793; ENSG00000164077 [Q86VX9-4]
ENST00000642691; ENSP00000494294; ENSG00000164077 [Q86VX9-5]
ENST00000645862; ENSP00000494452; ENSG00000164077 [Q86VX9-5]
GeneIDi84315
KEGGihsa:84315
UCSCiuc003cxz.4 human
uc003cya.4 human [Q86VX9-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
84315
DisGeNETi84315
EuPathDBiHostDB:ENSG00000164077.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MON1A

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0003326
HGNCiHGNC:28207 MON1A
HPAiHPA053752
HPA058032
MIMi611464 gene
neXtProtiNX_Q86VX9
OpenTargetsiENSG00000164077
PharmGKBiPA142671340

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0997 Eukaryota
ENOG410XR29 LUCA
GeneTreeiENSGT00390000006665
HOGENOMiHOG000031337
HOVERGENiHBG064381
InParanoidiQ86VX9
KOiK20195
OMAiTQLNHIF
OrthoDBi829786at2759
PhylomeDBiQ86VX9
TreeFamiTF314665

Enzyme and pathway databases

ReactomeiR-HSA-8876198 RAB GEFs exchange GTP for GDP on RABs

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
84315

Protein Ontology

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PROi
PR:Q86VX9

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000164077 Expressed in 172 organ(s), highest expression level in quadriceps femoris
ExpressionAtlasiQ86VX9 baseline and differential
GenevisibleiQ86VX9 HS

Family and domain databases

InterProiView protein in InterPro
IPR004353 Mon1
PANTHERiPTHR13027 PTHR13027, 1 hit
PfamiView protein in Pfam
PF03164 Mon1, 1 hit
PRINTSiPR01546 YEAST73DUF

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMON1A_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86VX9
Secondary accession number(s): B2RDQ1
, G5E9N1, Q8NAV7, Q9BRF3, X6R3V9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: March 28, 2018
Last modified: February 13, 2019
This is version 122 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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