Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 136 (17 Jun 2020)
Sequence version 2 (11 Jan 2011)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Ran-binding protein 3-like

Gene

RANBP3L

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Nuclear export factor for BMP-specific SMAD1/5/8 that plays a critical role in terminating BMP signaling and regulating mesenchymal stem cell differentiation by blocking osteoblast differentiation to promote myogenic differention. Directly recognizes dephosphorylated SMAD1/5/8 and mediates their nuclear export in a Ran-dependent manner.By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • Ran GTPase binding Source: GO_Central
  • SMAD binding Source: UniProtKB

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ran-binding protein 3-like
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RANBP3L
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000164188.8

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26353 RANBP3L

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
616391 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q86VV4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000164188

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162400660

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q86VV4 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RANBP3L

Domain mapping of disease mutations (DMDM)

More...
DMDMi
317373276

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003127491 – 465Ran-binding protein 3-likeAdd BLAST465

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
Q86VV4

PRoteomics IDEntifications database

More...
PRIDEi
Q86VV4

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
20364
70072 [Q86VV4-1]
70073 [Q86VV4-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q86VV4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q86VV4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000164188 Expressed in cortex of kidney and 91 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q86VV4 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q86VV4 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000164188 Tissue enhanced (brain, kidney)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with SMAD1, SMAD5 and SMAD8; the interaction (with SMAD at least) increases when SMAD1 is not phosphorylated and mediates SMAD1 nuclear export.

By similarity1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
128419, 3 interactors

Protein interaction database and analysis system

More...
IntActi
Q86VV4, 8 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000421853

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q86VV4 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q86VV4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini276 – 417RanBD1PROSITE-ProRule annotationAdd BLAST142

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161387

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_046714_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q86VV4

Identification of Orthologs from Complete Genome Data

More...
OMAi
NSTEQGP

Database of Orthologous Groups

More...
OrthoDBi
918488at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q86VV4

TreeFam database of animal gene trees

More...
TreeFami
TF313181

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.29.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011993 PH-like_dom_sf
IPR000156 Ran_bind_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00638 Ran_BP1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00160 RanBD, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50196 RANBD1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q86VV4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MTTIPRKGSS HLPGSLHTCK LKLQEDRRQQ EKSVIAQPIF VFEKGEQTFK
60 70 80 90 100
RPAEDTLYEA AEPECNGFPT KRVRSSSFTF HITDSQSQGV RKNNVFMTSA
110 120 130 140 150
LVQSSVDIKS AEQGPVKHSK HVIRPAILQL PQARSCAKVR KTFGHKALES
160 170 180 190 200
CKTKEKTNNK ISEGNSYLLS ENLSRARISV QLSTNQDFLG ATSVGCQPNE
210 220 230 240 250
DKCSFKSCSS NFVFGENMVE RVLGTQKLTQ PQLENDSYAK EKPFKSIPKF
260 270 280 290 300
PVNFLSSRTD SIKNTSLIES AAAFSSQPSR KCLLEKIDVI TGEETEHNVL
310 320 330 340 350
KINCKLFIFN KTTQSWIERG RGTLRLNDTA STDCGTLQSR LIMRNQGSLR
360 370 380 390 400
LILNSKLWAQ MKIQRANHKN VRITATDLED YSIKIFLIQA SAQDTAYLYA
410 420 430 440 450
AIHHRLVALQ SFNKQRDVNQ AESLSETAQQ LNCESCDENE DDFIQVTKNG
460
SDPSSWTHRQ SVACS
Length:465
Mass (Da):52,211
Last modified:January 11, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3A47BE51C1D34A64
GO
Isoform 2 (identifier: Q86VV4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     302-321: INCKLFIFNKTTQSWIERGR → VCISCFTLSGSIYILGIKLT
     322-465: Missing.

Show »
Length:321
Mass (Da):35,676
Checksum:i7ECD5FE3E46A7639
GO
Isoform 3 (identifier: Q86VV4-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     89-89: G → GVSTLSQKQMRCSSVTNLPTFPHSGP

Show »
Length:490
Mass (Da):54,896
Checksum:iC182AD65DD4168D7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6RCM9D6RCM9_HUMAN
Ran-binding protein 3-like
RANBP3L
108Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti181Q → R in BAH13852 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03755770T → R3 PublicationsCorresponds to variant dbSNP:rs1035480Ensembl.1
Natural variantiVAR_037558111A → D. Corresponds to variant dbSNP:rs35433829Ensembl.1
Natural variantiVAR_037559271A → V. Corresponds to variant dbSNP:rs16902872Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_04446389G → GVSTLSQKQMRCSSVTNLPT FPHSGP in isoform 3. 1 Publication1
Alternative sequenceiVSP_029893302 – 321INCKL…IERGR → VCISCFTLSGSIYILGIKLT in isoform 2. 1 PublicationAdd BLAST20
Alternative sequenceiVSP_029894322 – 465Missing in isoform 2. 1 PublicationAdd BLAST144

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK058151 mRNA Translation: BAB71689.1
AK302947 mRNA Translation: BAH13852.1
AC008807 Genomic DNA No translation available.
AC114277 Genomic DNA No translation available.
CH471119 Genomic DNA Translation: EAW55942.1
CH471119 Genomic DNA Translation: EAW55943.1
BC047660 mRNA Translation: AAH47660.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS3918.1 [Q86VV4-1]
CCDS54843.1 [Q86VV4-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001154901.1, NM_001161429.2 [Q86VV4-3]
NP_001310202.1, NM_001323273.1
NP_001310203.1, NM_001323274.1
NP_001310204.1, NM_001323275.1
NP_001310205.1, NM_001323276.1
NP_001310206.1, NM_001323277.1
NP_001310207.1, NM_001323278.1
NP_001310208.1, NM_001323279.1
NP_001310209.1, NM_001323280.1
NP_659437.3, NM_145000.4 [Q86VV4-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000296604; ENSP00000296604; ENSG00000164188 [Q86VV4-1]
ENST00000502994; ENSP00000421853; ENSG00000164188 [Q86VV4-3]
ENST00000515759; ENSP00000421149; ENSG00000164188 [Q86VV4-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
202151

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:202151

UCSC genome browser

More...
UCSCi
uc003jkh.4 human [Q86VV4-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK058151 mRNA Translation: BAB71689.1
AK302947 mRNA Translation: BAH13852.1
AC008807 Genomic DNA No translation available.
AC114277 Genomic DNA No translation available.
CH471119 Genomic DNA Translation: EAW55942.1
CH471119 Genomic DNA Translation: EAW55943.1
BC047660 mRNA Translation: AAH47660.1
CCDSiCCDS3918.1 [Q86VV4-1]
CCDS54843.1 [Q86VV4-3]
RefSeqiNP_001154901.1, NM_001161429.2 [Q86VV4-3]
NP_001310202.1, NM_001323273.1
NP_001310203.1, NM_001323274.1
NP_001310204.1, NM_001323275.1
NP_001310205.1, NM_001323276.1
NP_001310206.1, NM_001323277.1
NP_001310207.1, NM_001323278.1
NP_001310208.1, NM_001323279.1
NP_001310209.1, NM_001323280.1
NP_659437.3, NM_145000.4 [Q86VV4-1]

3D structure databases

SMRiQ86VV4
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi128419, 3 interactors
IntActiQ86VV4, 8 interactors
STRINGi9606.ENSP00000421853

PTM databases

iPTMnetiQ86VV4
PhosphoSitePlusiQ86VV4

Polymorphism and mutation databases

BioMutaiRANBP3L
DMDMi317373276

Proteomic databases

PeptideAtlasiQ86VV4
PRIDEiQ86VV4
ProteomicsDBi20364
70072 [Q86VV4-1]
70073 [Q86VV4-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
43549 91 antibodies

Genome annotation databases

EnsembliENST00000296604; ENSP00000296604; ENSG00000164188 [Q86VV4-1]
ENST00000502994; ENSP00000421853; ENSG00000164188 [Q86VV4-3]
ENST00000515759; ENSP00000421149; ENSG00000164188 [Q86VV4-2]
GeneIDi202151
KEGGihsa:202151
UCSCiuc003jkh.4 human [Q86VV4-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
202151
EuPathDBiHostDB:ENSG00000164188.8

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RANBP3L
HGNCiHGNC:26353 RANBP3L
HPAiENSG00000164188 Tissue enhanced (brain, kidney)
MIMi616391 gene
neXtProtiNX_Q86VV4
OpenTargetsiENSG00000164188
PharmGKBiPA162400660

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00940000161387
HOGENOMiCLU_046714_0_0_1
InParanoidiQ86VV4
OMAiNSTEQGP
OrthoDBi918488at2759
PhylomeDBiQ86VV4
TreeFamiTF313181

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
202151 2 hits in 787 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
202151
PharosiQ86VV4 Tdark

Protein Ontology

More...
PROi
PR:Q86VV4
RNActiQ86VV4 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000164188 Expressed in cortex of kidney and 91 other tissues
ExpressionAtlasiQ86VV4 baseline and differential
GenevisibleiQ86VV4 HS

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR011993 PH-like_dom_sf
IPR000156 Ran_bind_dom
PfamiView protein in Pfam
PF00638 Ran_BP1, 1 hit
SMARTiView protein in SMART
SM00160 RanBD, 1 hit
PROSITEiView protein in PROSITE
PS50196 RANBD1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRNB3L_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86VV4
Secondary accession number(s): B7Z866, E9PGP9, Q96LK2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: January 11, 2011
Last modified: June 17, 2020
This is version 136 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again