UniProtKB - Q86VM6 (Q86VM6_HUMAN)
Protein
Submitted name:
MBNL1 protein
Gene
MBNL1
Organism
Homo sapiens (Human)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 1 – 16 | C3H1-typePROSITE-ProRule annotationAdd BLAST | 16 | |
Zinc fingeri | 122 – 150 | C3H1-typePROSITE-ProRule annotationAdd BLAST | 29 | |
Zinc fingeri | 158 – 184 | C3H1-typePROSITE-ProRule annotationAdd BLAST | 27 |
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: MBNL1 proteinImportedSubmitted name: Muscleblind-like (Drosophila), isoform CRA_fImportedSubmitted name: Muscleblind-like protein 1Imported |
Gene namesi | Name:MBNL1Imported ORF Names:hCG_28028Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:6923, MBNL1 |
VEuPathDBi | HostDB:ENSG00000152601.17 |
Subcellular locationi
Cytosol
- cytosol Source: HPA
Nucleus
- nucleoplasm Source: HPA
Expressioni
Gene expression databases
Bgeei | ENSG00000152601, Expressed in calcaneal tendon and 259 other tissues |
ExpressionAtlasi | Q86VM6, baseline and differential |
Interactioni
Binary interactionsi
Hide detailsQ86VM6
With | #Exp. | IntAct |
---|---|---|
AEN [Q8WTP8] | 3 | EBI-10225084,EBI-8637627 |
ATXN1 [P54253] | 6 | EBI-10225084,EBI-930964 |
DAB1 [O75553] | 3 | EBI-10225084,EBI-7875264 |
TLE5 [Q08117] | 3 | EBI-10225084,EBI-717810 |
Protein-protein interaction databases
IntActi | Q86VM6, 4 interactors |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 16 | C3H1-typeInterPro annotationAdd BLAST | 16 | |
Domaini | 122 – 150 | C3H1-typeInterPro annotationAdd BLAST | 29 | |
Domaini | 158 – 184 | C3H1-typeInterPro annotationAdd BLAST | 27 |
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 1 – 16 | C3H1-typePROSITE-ProRule annotationAdd BLAST | 16 | |
Zinc fingeri | 122 – 150 | C3H1-typePROSITE-ProRule annotationAdd BLAST | 29 | |
Zinc fingeri | 158 – 184 | C3H1-typePROSITE-ProRule annotationAdd BLAST | 27 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
GeneTreei | ENSGT00950000182897 |
OrthoDBi | 1543798at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR000571, Znf_CCCH |
Pfami | View protein in Pfam PF00642, zf-CCCH, 1 hit |
SMARTi | View protein in SMART SM00356, ZnF_C3H1, 2 hits |
PROSITEi | View protein in PROSITE PS50103, ZF_C3H1, 3 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All
Q86VM6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGRCSRENCK YLHPPPHLKT QLEINGRNNL IQQKNMAMLA QQMQLANAMM
60 70 80 90 100
PGAPLQPVPM FSVAPSLATN ASAAAFNPYL GPVSPSLVPA EILPTAPMLV
110 120 130 140 150
TGNPGVPVPA AAAAAAQKLM RTDRLEVCRE YQRGNCNRGE NDCRFAHPAD
160 170 180 190 200
STMIDTNDNT VTVCMDYIKG RCSREKCKYF HPPAHLQAKI KAAQYQVNQA
210 220 230 240 250
AAAQAAATAA AMTQSAVKSL KRPLEATFDL GIPQAVLPPL PKRPALEKTN
260 270 280 290 300
GATAVFNTGI FQYQQALANM QLQQHTAFLP PGSILCMTPA TSVVPMVHGA
310 320 330 340
TPATVSAATT SATSVPFAAT ATANQIPIIS AEHLTSHKYV TQM
Computationally mapped potential isoform sequencesi
There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9NR56 | MBNL1_HUMAN | Muscleblind-like protein 1 | MBNL1 EXP, KIAA0428, MBNL | 388 | Annotation score: | ||
A0A0A0MQX8 | A0A0A0MQX8_HUMAN | Muscleblind-like protein 1 | MBNL1 | 400 | Annotation score: | ||
C9JP00 | C9JP00_HUMAN | Muscleblind-like protein 1 | MBNL1 | 348 | Annotation score: | ||
H7C4Y1 | H7C4Y1_HUMAN | Muscleblind-like protein 1 | MBNL1 | 210 | Annotation score: | ||
C9JCX1 | C9JCX1_HUMAN | Muscleblind-like protein 1 | MBNL1 | 155 | Annotation score: | ||
H7C4T5 | H7C4T5_HUMAN | Muscleblind-like protein 1 | MBNL1 | 329 | Annotation score: | ||
C9J7P7 | C9J7P7_HUMAN | Muscleblind-like protein 1 | MBNL1 | 90 | Annotation score: | ||
C9J4T8 | C9J4T8_HUMAN | Muscleblind-like protein 1 | MBNL1 | 58 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC026347 Genomic DNA No translation available. AC106722 Genomic DNA No translation available. BC050535 mRNA Translation: AAH50535.1 CH471052 Genomic DNA Translation: EAW78780.1 |
RefSeqi | NP_001300986.1, NM_001314057.1 NP_997178.1, NM_207295.1 NP_997179.1, NM_207296.1 NP_997180.1, NM_207297.1 |
Genome annotation databases
Ensembli | ENST00000493459; ENSP00000419347; ENSG00000152601 |
GeneIDi | 4154 |
UCSCi | uc003ezj.4, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC026347 Genomic DNA No translation available. AC106722 Genomic DNA No translation available. BC050535 mRNA Translation: AAH50535.1 CH471052 Genomic DNA Translation: EAW78780.1 |
RefSeqi | NP_001300986.1, NM_001314057.1 NP_997178.1, NM_207295.1 NP_997179.1, NM_207296.1 NP_997180.1, NM_207297.1 |
3D structure databases
SMRi | Q86VM6 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | Q86VM6, 4 interactors |
Proteomic databases
MaxQBi | Q86VM6 |
PRIDEi | Q86VM6 |
ProteomicsDBi | 70040 |
Protocols and materials databases
Antibodypediai | 4292, 337 antibodies |
Genome annotation databases
Ensembli | ENST00000493459; ENSP00000419347; ENSG00000152601 |
GeneIDi | 4154 |
UCSCi | uc003ezj.4, human |
Organism-specific databases
CTDi | 4154 |
HGNCi | HGNC:6923, MBNL1 |
OpenTargetsi | ENSG00000152601 |
VEuPathDBi | HostDB:ENSG00000152601.17 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00950000182897 |
OrthoDBi | 1543798at2759 |
Miscellaneous databases
BioGRID-ORCSi | 4154, 75 hits in 888 CRISPR screens |
ChiTaRSi | MBNL1, human |
GenomeRNAii | 4154 |
Gene expression databases
Bgeei | ENSG00000152601, Expressed in calcaneal tendon and 259 other tissues |
ExpressionAtlasi | Q86VM6, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR000571, Znf_CCCH |
Pfami | View protein in Pfam PF00642, zf-CCCH, 1 hit |
SMARTi | View protein in SMART SM00356, ZnF_C3H1, 2 hits |
PROSITEi | View protein in PROSITE PS50103, ZF_C3H1, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q86VM6_HUMAN | |
Accessioni | Q86VM6Primary (citable) accession number: Q86VM6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 1, 2003 |
Last sequence update: | June 1, 2003 | |
Last modified: | February 10, 2021 | |
This is version 141 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |