UniProtKB - Q86VL0 (Q86VL0_HUMAN)
Protein
Submitted name:
TCEA2 protein
Gene
TCEA2
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- translation elongation factor activity Source: UniProtKB-KW
GO - Biological processi
- transcription, DNA-templated Source: InterPro
Keywordsi
Molecular function | Elongation factorImported |
Biological process | Protein biosynthesis |
Names & Taxonomyi
Protein namesi | Submitted name: TCEA2 proteinImportedSubmitted name: Transcription elongation factor A (SII), 2, isoform CRA_bImportedSubmitted name: Transcription elongation factor A protein 2Imported |
Gene namesi | Name:TCEA2Imported ORF Names:hCG_2021465Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:11614, TCEA2 |
VEuPathDBi | HostDB:ENSG00000171703.16 |
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Cytoskeleton
- centrosome Source: HPA
Nucleus
- nucleoplasm Source: HPA
Keywords - Cellular componenti
NucleusARBA annotationExpressioni
Gene expression databases
Bgeei | ENSG00000171703, Expressed in right hemisphere of cerebellum and 223 other tissues |
ExpressionAtlasi | Q86VL0, baseline and differential |
Interactioni
Binary interactionsi
Hide detailsProtein-protein interaction databases
IntActi | Q86VL0, 3 interactors |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 6 – 83 | TFIIS N-terminalInterPro annotationAdd BLAST | 78 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 87 – 128 | DisorderedSequence analysisAdd BLAST | 42 |
Phylogenomic databases
GeneTreei | ENSGT00940000159974 |
Family and domain databases
Gene3Di | 1.10.472.30, 1 hit 1.20.930.10, 1 hit |
InterProi | View protein in InterPro IPR003617, TFIIS/CRSP70_N_sub IPR035441, TFIIS/LEDGF_dom_sf IPR036575, TFIIS_cen_dom_sf IPR017923, TFIIS_N |
Pfami | View protein in Pfam PF08711, Med26, 1 hit |
SMARTi | View protein in SMART SM00509, TFS2N, 1 hit |
SUPFAMi | SSF46942, SSF46942, 1 hit SSF47676, SSF47676, 1 hit |
PROSITEi | View protein in PROSITE PS51319, TFIIS_N, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
Q86VL0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MMGKEEEIAR IARRLDKMVT KKSAEGAMDL LRELKAMPIT LHLLQSTRVG
60 70 80 90 100
MSVNALRKQS SDEEVIALAK SLIKSWKKLL DASDAKARER GRGMPLPTSS
110 120 130 140 150
RDASEAPDPS RKRPELPRAP STPRITTFPP VPVTCDAVRN KCREMLTAAL
160 170 180 190 200
QTDHDHVAIG ADCERLSAQI EEYILWVGAV GLGFWWSQEA AWPGALWWLL
210 220 230 240
DATAQLSRGH LPGWSPAWVV RLSHLRRAPG PAEGLILSAC GA
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ15560 | TCEA2_HUMAN | Transcription elongation factor A p... | TCEA2 | 299 | Annotation score: | ||
A0A0A0MT58 | A0A0A0MT58_HUMAN | Transcription elongation factor A p... | TCEA2 | 270 | Annotation score: | ||
Q5JRI7 | Q5JRI7_HUMAN | Transcription elongation factor A p... | TCEA2 | 246 | Annotation score: | ||
Q5JRI8 | Q5JRI8_HUMAN | Transcription elongation factor A p... | TCEA2 | 82 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL355803 Genomic DNA No translation available. AL590548 Genomic DNA No translation available. BC050623 mRNA Translation: AAH50623.1 CH471077 Genomic DNA Translation: EAW75169.1 |
Genome annotation databases
Ensembli | ENST00000395053; ENSP00000378493; ENSG00000171703 |
UCSCi | uc061yqw.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL355803 Genomic DNA No translation available. AL590548 Genomic DNA No translation available. BC050623 mRNA Translation: AAH50623.1 CH471077 Genomic DNA Translation: EAW75169.1 |
3D structure databases
SMRi | Q86VL0 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | Q86VL0, 3 interactors |
Proteomic databases
MaxQBi | Q86VL0 |
PRIDEi | Q86VL0 |
ProteomicsDBi | 70033 |
Protocols and materials databases
Antibodypediai | 15504, 133 antibodies |
DNASUi | 6919 |
Genome annotation databases
Ensembli | ENST00000395053; ENSP00000378493; ENSG00000171703 |
UCSCi | uc061yqw.1, human |
Organism-specific databases
HGNCi | HGNC:11614, TCEA2 |
OpenTargetsi | ENSG00000171703 |
VEuPathDBi | HostDB:ENSG00000171703.16 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000159974 |
Gene expression databases
Bgeei | ENSG00000171703, Expressed in right hemisphere of cerebellum and 223 other tissues |
ExpressionAtlasi | Q86VL0, baseline and differential |
Family and domain databases
Gene3Di | 1.10.472.30, 1 hit 1.20.930.10, 1 hit |
InterProi | View protein in InterPro IPR003617, TFIIS/CRSP70_N_sub IPR035441, TFIIS/LEDGF_dom_sf IPR036575, TFIIS_cen_dom_sf IPR017923, TFIIS_N |
Pfami | View protein in Pfam PF08711, Med26, 1 hit |
SMARTi | View protein in SMART SM00509, TFS2N, 1 hit |
SUPFAMi | SSF46942, SSF46942, 1 hit SSF47676, SSF47676, 1 hit |
PROSITEi | View protein in PROSITE PS51319, TFIIS_N, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q86VL0_HUMAN | |
Accessioni | Q86VL0Primary (citable) accession number: Q86VL0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 1, 2003 |
Last sequence update: | June 1, 2003 | |
Last modified: | April 7, 2021 | |
This is version 144 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |