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Entry version 109 (08 May 2019)
Sequence version 1 (01 Jun 2003)
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Protein

2-acylglycerol O-acyltransferase 3

Gene

MOGAT3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Also able to catalyze the terminal step in triacylglycerol synthesis by using diacylglycerol and fatty acyl-CoA as substrates. Has a preference toward palmitoyl-CoA and oleoyl-CoA. May be involved in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes.2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

    1. Vmax=9.3 nmol/min/mg enzyme with diacylglycerol as substrate1 Publication
    2. Vmax=22.8 nmol/min/mg enzyme with 2-monoacylglycerol as substrate1 Publication

    <p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: triacylglycerol biosynthesis

    This protein is involved in the pathway triacylglycerol biosynthesis, which is part of Glycerolipid metabolism.1 Publication
    View all proteins of this organism that are known to be involved in the pathway triacylglycerol biosynthesis and in Glycerolipid metabolism.

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    GO - Biological processi

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Molecular functionAcyltransferase, Transferase
    Biological processGlycerol metabolism, Lipid biosynthesis, Lipid metabolism

    Enzyme and pathway databases

    BRENDA Comprehensive Enzyme Information System

    More...
    BRENDAi
    2.3.1.22 2681

    Reactome - a knowledgebase of biological pathways and processes

    More...
    Reactomei
    R-HSA-75109 Triglyceride biosynthesis

    UniPathway: a resource for the exploration and annotation of metabolic pathways

    More...
    UniPathwayi
    UPA00282

    Chemistry databases

    SwissLipids knowledge resource for lipid biology

    More...
    SwissLipidsi
    SLP:000000307

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    2-acylglycerol O-acyltransferase 3Curated (EC:2.3.1.201 Publication, EC:2.3.1.221 Publication)
    Alternative name(s):
    Acyl-CoA:monoacylglycerol acyltransferase 31 Publication
    Short name:
    MGAT31 Publication
    Diacylglycerol O-acyltransferase candidate 7
    Short name:
    hDC7
    Diacylglycerol acyltransferase 2-like protein 7
    Monoacylglycerol O-acyltransferase 3
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:MOGAT3Imported
    Synonyms:DC7, DGAT2L7
    ORF Names:UNQ9383/PRO34208
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

    Organism-specific databases

    Human Gene Nomenclature Database

    More...
    HGNCi
    HGNC:23249 MOGAT3

    Online Mendelian Inheritance in Man (OMIM)

    More...
    MIMi
    610184 gene

    neXtProt; the human protein knowledge platform

    More...
    neXtProti
    NX_Q86VF5

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

    Topology

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei29 – 49HelicalSequence analysisAdd BLAST21
    Transmembranei50 – 70HelicalSequence analysisAdd BLAST21
    Transmembranei137 – 157HelicalSequence analysisAdd BLAST21

    Keywords - Cellular componenti

    Cytoplasm, Endoplasmic reticulum, Membrane

    <p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

    Mutagenesis

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi265C → A: Reduces 60% 2-acylglycerol O-acyltransferase activity. No effect on diacylglycerol O-acyltransferase activity. 1 Publication1
    Mutagenesisi265C → Y: Catalitically inactive. No 2-acylglycerol O-acyltransferase neither diacylglycerol O-acyltransferase activities. 1 Publication1

    Organism-specific databases

    DisGeNET

    More...
    DisGeNETi
    346606

    Open Targets

    More...
    OpenTargetsi
    ENSG00000106384

    The Pharmacogenetics and Pharmacogenomics Knowledge Base

    More...
    PharmGKBi
    PA134959238

    Polymorphism and mutation databases

    BioMuta curated single-nucleotide variation and disease association database

    More...
    BioMutai
    MOGAT3

    Domain mapping of disease mutations (DMDM)

    More...
    DMDMi
    74727570

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002490671 – 3412-acylglycerol O-acyltransferase 3Add BLAST341

    Amino acid modifications

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi126N-linked (GlcNAc...) asparagineSequence analysis1

    <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

    Ubiquitinated. Ubiquitination leads to proteasomal degradation.1 Publication

    Keywords - PTMi

    Glycoprotein, Ubl conjugation

    Proteomic databases

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    Q86VF5

    PeptideAtlas

    More...
    PeptideAtlasi
    Q86VF5

    PRoteomics IDEntifications database

    More...
    PRIDEi
    Q86VF5

    ProteomicsDB human proteome resource

    More...
    ProteomicsDBi
    70001
    70002 [Q86VF5-2]
    70003 [Q86VF5-3]

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    <p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

    Selectively expressed in the digestive system. Highly expressed in the ileum, and at lower level in jejunum, duodenum, colon, cecum and the rectum. Not expressed in the stomach and the esophagus and trachea. Expressed at very low level in liver.1 Publication

    Gene expression databases

    Bgee dataBase for Gene Expression Evolution

    More...
    Bgeei
    ENSG00000106384 Expressed in 24 organ(s), highest expression level in mucosa of transverse colon

    Genevisible search portal to normalized and curated expression data from Genevestigator

    More...
    Genevisiblei
    Q86VF5 HS

    Organism-specific databases

    Human Protein Atlas

    More...
    HPAi
    HPA011940

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    Protein-protein interaction databases

    The Biological General Repository for Interaction Datasets (BioGrid)

    More...
    BioGridi
    131392, 1 interactor

    STRING: functional protein association networks

    More...
    STRINGi
    9606.ENSP00000223114

    <p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

    3D structure databases

    SWISS-MODEL Repository - a database of annotated 3D protein structure models

    More...
    SMRi
    Q86VF5

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    <p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    KOG0831 Eukaryota
    ENOG410XTG3 LUCA

    Ensembl GeneTree

    More...
    GeneTreei
    ENSGT00950000182761

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...
    HOGENOMi
    HOG000179738

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    Q86VF5

    KEGG Orthology (KO)

    More...
    KOi
    K14456

    Identification of Orthologs from Complete Genome Data

    More...
    OMAi
    FAPCIFW

    Database of Orthologous Groups

    More...
    OrthoDBi
    1347007at2759

    Database for complete collections of gene phylogenies

    More...
    PhylomeDBi
    Q86VF5

    TreeFam database of animal gene trees

    More...
    TreeFami
    TF314707

    Family and domain databases

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR007130 DAGAT

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF03982 DAGAT, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
    Isoform 1 (identifier: Q86VF5-1) [UniParc]FASTAAdd to basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide
            10         20         30         40         50
    MGVATTLQPP TTSKTLQKQH LEAVGAYQYV LTFLFMGPFF SLLVFVLLFT
    60 70 80 90 100
    SLWPFSVFYL VWLYVDWDTP NQGGRRSEWI RNRAIWRQLR DYYPVKLVKT
    110 120 130 140 150
    AELPPDRNYV LGAHPHGIMC TGFLCNFSTE SNGFSQLFPG LRPWLAVLAG
    160 170 180 190 200
    LFYLPVYRDY IMSFGLCPVS RQSLDFILSQ PQLGQAVVIM VGGAHEALYS
    210 220 230 240 250
    VPGEHCLTLQ KRKGFVRLAL RHGASLVPVY SFGENDIFRL KAFATGSWQH
    260 270 280 290 300
    WCQLTFKKLM GFSPCIFWGR GLFSATSWGL LPFAVPITTV VGRPIPVPQR
    310 320 330 340
    LHPTEEEVNH YHALYMTALE QLFEEHKESC GVPASTCLTF I
    Length:341
    Mass (Da):38,730
    Last modified:June 1, 2003 - v1
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3F4981AE0D05B613
    GO
    Isoform 2 (identifier: Q86VF5-2) [UniParc]FASTAAdd to basket

    The sequence of this isoform differs from the canonical sequence as follows:
         224-281: ASLVPVYSFG...LFSATSWGLL → GPPHPRPPAP...LHLGLAAAFR
         282-341: Missing.

    Note: No experimental confirmation available.
    Show »
    Length:281
    Mass (Da):31,498
    Checksum:iD1D0C8B2EF0D3992
    GO
    Isoform 3 (identifier: Q86VF5-3) [UniParc]FASTAAdd to basket

    The sequence of this isoform differs from the canonical sequence as follows:
         291-341: VGRPIPVPQR...VPASTCLTFI → GECPPPGGRP...RKSITITPST

    Note: No experimental confirmation available.
    Show »
    Length:344
    Mass (Da):38,353
    Checksum:i3836BCF9E68C500C
    GO

    <p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

    The sequence AAD45832 differs from that shown. Reason: Erroneous gene model prediction.Curated

    Experimental Info

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti265C → Y in AAI00954 (PubMed:15489334).Curated1

    Alternative sequence

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_020361224 – 281ASLVP…SWGLL → GPPHPRPPAPPPHRGGSQSL SRPLHDGPGAALRGAQGKLW GPRFHLPHLHLGLAAAFR in isoform 2. 1 PublicationAdd BLAST58
    Alternative sequenceiVSP_020362282 – 341Missing in isoform 2. 1 PublicationAdd BLAST60
    Alternative sequenceiVSP_020363291 – 341VGRPI…CLTFI → GECPPPGGRPPAAAWASGIP RPPVSLSLQWAAPSPSPSAS TPPRRKSITITPST in isoform 3. 1 PublicationAdd BLAST51

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    AY229854 mRNA Translation: AAO63579.1
    AY358200 mRNA Translation: AAQ88567.1
    AC004876 Genomic DNA Translation: AAD45832.1 Sequence problems.
    BC100953 mRNA Translation: AAI00954.1
    BC100954 mRNA Translation: AAI00955.1
    BC100955 mRNA Translation: AAI00956.1

    The Consensus CDS (CCDS) project

    More...
    CCDSi
    CCDS5714.1 [Q86VF5-1]
    CCDS75643.1 [Q86VF5-2]

    NCBI Reference Sequences

    More...
    RefSeqi
    NP_001274076.1, NM_001287147.1 [Q86VF5-2]
    NP_835470.1, NM_178176.3 [Q86VF5-1]
    XP_005250366.1, XM_005250309.3 [Q86VF5-3]

    Genome annotation databases

    Ensembl eukaryotic genome annotation project

    More...
    Ensembli
    ENST00000223114; ENSP00000223114; ENSG00000106384 [Q86VF5-1]
    ENST00000379423; ENSP00000368734; ENSG00000106384 [Q86VF5-2]
    ENST00000440203; ENSP00000403756; ENSG00000106384 [Q86VF5-3]

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    346606

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    hsa:346606

    UCSC genome browser

    More...
    UCSCi
    uc003uyc.5 human [Q86VF5-1]

    Keywords - Coding sequence diversityi

    Alternative splicing

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    AY229854 mRNA Translation: AAO63579.1
    AY358200 mRNA Translation: AAQ88567.1
    AC004876 Genomic DNA Translation: AAD45832.1 Sequence problems.
    BC100953 mRNA Translation: AAI00954.1
    BC100954 mRNA Translation: AAI00955.1
    BC100955 mRNA Translation: AAI00956.1
    CCDSiCCDS5714.1 [Q86VF5-1]
    CCDS75643.1 [Q86VF5-2]
    RefSeqiNP_001274076.1, NM_001287147.1 [Q86VF5-2]
    NP_835470.1, NM_178176.3 [Q86VF5-1]
    XP_005250366.1, XM_005250309.3 [Q86VF5-3]

    3D structure databases

    SMRiQ86VF5
    ModBaseiSearch...
    MobiDBiSearch...

    Protein-protein interaction databases

    BioGridi131392, 1 interactor
    STRINGi9606.ENSP00000223114

    Chemistry databases

    SwissLipidsiSLP:000000307

    Polymorphism and mutation databases

    BioMutaiMOGAT3
    DMDMi74727570

    Proteomic databases

    PaxDbiQ86VF5
    PeptideAtlasiQ86VF5
    PRIDEiQ86VF5
    ProteomicsDBi70001
    70002 [Q86VF5-2]
    70003 [Q86VF5-3]

    Protocols and materials databases

    Structural Biology KnowledgebaseSearch...

    Genome annotation databases

    EnsembliENST00000223114; ENSP00000223114; ENSG00000106384 [Q86VF5-1]
    ENST00000379423; ENSP00000368734; ENSG00000106384 [Q86VF5-2]
    ENST00000440203; ENSP00000403756; ENSG00000106384 [Q86VF5-3]
    GeneIDi346606
    KEGGihsa:346606
    UCSCiuc003uyc.5 human [Q86VF5-1]

    Organism-specific databases

    Comparative Toxicogenomics Database

    More...
    CTDi
    346606
    DisGeNETi346606

    GeneCards: human genes, protein and diseases

    More...
    GeneCardsi
    MOGAT3
    HGNCiHGNC:23249 MOGAT3
    HPAiHPA011940
    MIMi610184 gene
    neXtProtiNX_Q86VF5
    OpenTargetsiENSG00000106384
    PharmGKBiPA134959238

    GenAtlas: human gene database

    More...
    GenAtlasi
    Search...

    Phylogenomic databases

    eggNOGiKOG0831 Eukaryota
    ENOG410XTG3 LUCA
    GeneTreeiENSGT00950000182761
    HOGENOMiHOG000179738
    InParanoidiQ86VF5
    KOiK14456
    OMAiFAPCIFW
    OrthoDBi1347007at2759
    PhylomeDBiQ86VF5
    TreeFamiTF314707

    Enzyme and pathway databases

    UniPathwayi
    UPA00282

    BRENDAi2.3.1.22 2681
    ReactomeiR-HSA-75109 Triglyceride biosynthesis

    Miscellaneous databases

    Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

    More...
    GenomeRNAii
    346606

    Protein Ontology

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    PROi
    PR:Q86VF5

    The Stanford Online Universal Resource for Clones and ESTs

    More...
    SOURCEi
    Search...

    Gene expression databases

    BgeeiENSG00000106384 Expressed in 24 organ(s), highest expression level in mucosa of transverse colon
    GenevisibleiQ86VF5 HS

    Family and domain databases

    InterProiView protein in InterPro
    IPR007130 DAGAT
    PfamiView protein in Pfam
    PF03982 DAGAT, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...
    ProtoNeti
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMOGT3_HUMAN
    <p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86VF5
    Secondary accession number(s): Q496A6
    , Q496A7, Q496A8, Q9UDW7
    <p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 5, 2006
    Last sequence update: June 1, 2003
    Last modified: May 8, 2019
    This is version 109 of the entry and version 1 of the sequence. See complete history.
    <p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    <p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 7
      Human chromosome 7: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families
    3. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    4. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    UniProt is an ELIXIR core data resource
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