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UniProtKB - Q86VE3 (SATL1_HUMAN)

Entry version 127 (10 Feb 2021)
Sequence version 4 (18 Sep 2019)
Previous versions | rss
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Protein

Spermidine/spermine N(1)-acetyltransferase-like protein 1

Gene

SATL1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei676SubstrateBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q86VE3

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Spermidine/spermine N(1)-acetyltransferase-like protein 1 (EC:2.3.1.-)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SATL1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:27992, SATL1

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q86VE3

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000184788.12

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000184788

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134969637

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q86VE3, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		SATL1

Domain mapping of disease mutations (DMDM)

More...DMDMi		143583359

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002829281 – 695Spermidine/spermine N(1)-acetyltransferase-like protein 1Add BLAST695

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q86VE3

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q86VE3

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q86VE3

PeptideAtlas

More...PeptideAtlasi		Q86VE3

PRoteomics IDEntifications database

More...PRIDEi		Q86VE3

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		19160
69991 [Q86VE3-1]
69992 [Q86VE3-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q86VE3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q86VE3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000184788, Expressed in dorsolateral prefrontal cortex and 27 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q86VE3, baseline and differential

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000184788, Group enriched (adrenal gland, brain, pituitary gland, testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000425421

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q86VE3, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q86VE3

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini529 – 695N-acetyltransferasePROSITE-ProRule annotationAdd BLAST167

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni552 – 553Substrate bindingBy similarity2
Regioni618 – 620Acetyl-CoA bindingBy similarity3
Regioni626 – 631Acetyl-CoA bindingBy similarity6
Regioni650 – 652Substrate bindingBy similarity3

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi195 – 523Gln-richAdd BLAST329

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the acetyltransferase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3216, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00950000183121

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_052128_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q86VE3

Identification of Orthologs from Complete Genome Data

More...OMAi		HPGMWQP

Database of Orthologous Groups

More...OrthoDBi		1228251at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q86VE3

TreeFam database of animal gene trees

More...TreeFami		TF319736

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR016181, Acyl_CoA_acyltransferase
IPR000182, GNAT_dom
IPR039533, Satl1

The PANTHER Classification System

More...PANTHERi		PTHR10545:SF60, PTHR10545:SF60, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00583, Acetyltransf_1, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF55729, SSF55729, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51186, GNAT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q86VE3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MNQSGTNQSS LSDSNQAGIN QPSTNSLGMN QMDMNQGSAS LYEMNQVDMK 
        60         70         80         90        100
QPSMSQAGMR QSGTNLPDIN QPDMKQPDTW QLGRSQPGML QQELSQLVLS 
       110        120        130        140        150
KAGISQPDPS QPGPSQSGPS QSRMRQIGTN QSGMSQPVMQ QLDSQSGGSQ 
       160        170        180        190        200
PSMRQVGTSQ LGTSQIGMSQ PGTWQTGLSQ PVLRQPNMSP PGMWQPGVQQ 
       210        220        230        240        250
PGISQQVPSH PDMSQPGMSQ QVPSQPGIRQ PDTSQSCKNQ TDMSQPDANQ 
       260        270        280        290        300
SSLSDSNQTG IIQPSPSLLG MNQMDMNQWS ASLYEMNQVD MKQPSMSQAG 
       310        320        330        340        350
MRQSGTNLPD INQPGMKQPG TWQLGRSQPG MWPQSLSELV LSEASISQPG 
       360        370        380        390        400
PPQRAPSQSG PRQSSTSQAG TNQSGISQPV MWQLDMRQSG GSQPSMRQVG 
       410        420        430        440        450
TSQSGTSQIG MSQPGTWQTG LSQPVPRQPN KSPPGMWQRG MWQPGMSQQV 
       460        470        480        490        500
PSQLGMRQPG TSQSSKNQTG MSHPGRGQPG IWEPGPSQPG LSQQDLNQLV 
       510        520        530        540        550
LSQPGLSQPG RSQPSVSQMG MRQTSMDYFQ IRHAEAGDCP EILRLIKELA 
       560        570        580        590        600
ACENMLDAME LTAADLLRDG FGDNPLFYCL IAEVNDQQKP SGKLTVGFAM 
       610        620        630        640        650
YYFTYDSWTG KVLYLEDFYV TQAYQGLGIG AEMLKRLSQI AITTQCNCMH 
       660        670        680        690 
FLVVIWNQAS INYYTSRGAL DLSSEEGWHL FRFNREELLD MAWEE
Length:695
Mass (Da):75,812
Last modified:September 18, 2019 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i198271758632AEE1
GO
Isoform 2 (identifier: Q86VE3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     626-632: GLGIGAE → DSHHNSM
     633-695: Missing.

Show »
Length:632
Mass (Da):68,530
Checksum:i53B23E9AB1BEEB0B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2R8YFQ0A0A2R8YFQ0_HUMAN
Spermidine/spermine N(1)-acetyltran...
SATL1
676Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5F9UUY5A0A5F9UUY5_HUMAN
Spermidine/spermine N(1)-acetyltran...
SATL1
508Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti176T → S in AAH43215 (PubMed:15772651).Curated1
Sequence conflicti179S → G in AAH43215 (PubMed:15772651).Curated1
Sequence conflicti426P → L in AAI26402 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_031438279W → R1 PublicationCorresponds to variant dbSNP:rs10126146Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_024253626 – 632GLGIGAE → DSHHNSM in isoform 2. 1 Publication7
Alternative sequenceiVSP_024254633 – 695Missing in isoform 2. 1 PublicationAdd BLAST63

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
Z99571 Genomic DNA No translation available.
BC043215 mRNA Translation: AAH43215.2
BC126401 mRNA Translation: AAI26402.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS35343.2 [Q86VE3-2]

NCBI Reference Sequences

More...RefSeqi		NP_001012998.2, NM_001012980.2 [Q86VE3-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000509231; ENSP00000425421; ENSG00000184788 [Q86VE3-2]
ENST00000644105; ENSP00000494345; ENSG00000184788 [Q86VE3-1]
ENST00000646118; ENSP00000493598; ENSG00000184788 [Q86VE3-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		340562

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:340562

UCSC genome browser

More...UCSCi		uc004een.4, human [Q86VE3-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z99571 Genomic DNA No translation available.
BC043215 mRNA Translation: AAH43215.2
BC126401 mRNA Translation: AAI26402.1
CCDSiCCDS35343.2 [Q86VE3-2]
RefSeqiNP_001012998.2, NM_001012980.2 [Q86VE3-2]

3D structure databases

SMRiQ86VE3
ModBaseiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000425421

PTM databases

iPTMnetiQ86VE3
PhosphoSitePlusiQ86VE3

Genetic variation databases

BioMutaiSATL1
DMDMi143583359

Proteomic databases

jPOSTiQ86VE3
MassIVEiQ86VE3
PaxDbiQ86VE3
PeptideAtlasiQ86VE3
PRIDEiQ86VE3
ProteomicsDBi19160
69991 [Q86VE3-1]
69992 [Q86VE3-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		54033, 60 antibodies

Genome annotation databases

EnsembliENST00000509231; ENSP00000425421; ENSG00000184788 [Q86VE3-2]
ENST00000644105; ENSP00000494345; ENSG00000184788 [Q86VE3-1]
ENST00000646118; ENSP00000493598; ENSG00000184788 [Q86VE3-1]
GeneIDi340562
KEGGihsa:340562
UCSCiuc004een.4, human [Q86VE3-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		340562

GeneCards: human genes, protein and diseases

More...GeneCardsi		SATL1
HGNCiHGNC:27992, SATL1
HPAiENSG00000184788, Group enriched (adrenal gland, brain, pituitary gland, testis)
neXtProtiNX_Q86VE3
OpenTargetsiENSG00000184788
PharmGKBiPA134969637
VEuPathDBiHostDB:ENSG00000184788.12

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3216, Eukaryota
GeneTreeiENSGT00950000183121
HOGENOMiCLU_052128_1_0_1
InParanoidiQ86VE3
OMAiHPGMWQP
OrthoDBi1228251at2759
PhylomeDBiQ86VE3
TreeFamiTF319736

Enzyme and pathway databases

PathwayCommonsiQ86VE3

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		340562, 4 hits in 501 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		SATL1, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		340562
PharosiQ86VE3, Tdark

Protein Ontology

More...PROi		PR:Q86VE3
RNActiQ86VE3, protein

Gene expression databases

BgeeiENSG00000184788, Expressed in dorsolateral prefrontal cortex and 27 other tissues
ExpressionAtlasiQ86VE3, baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR016181, Acyl_CoA_acyltransferase
IPR000182, GNAT_dom
IPR039533, Satl1
PANTHERiPTHR10545:SF60, PTHR10545:SF60, 1 hit
PfamiView protein in Pfam
PF00583, Acetyltransf_1, 1 hit
SUPFAMiSSF55729, SSF55729, 1 hit
PROSITEiView protein in PROSITE
PS51186, GNAT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSATL1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86VE3
Secondary accession number(s): A0A2R8Y5C1
, A0AVK7, E9PB72, Q5H8V9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: September 18, 2019
Last modified: February 10, 2021
This is version 127 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human variants curated from literature reports
    Index of human variants curated from literature reports
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  4. Human entries with genetic variants
    List of human entries with genetic variants
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