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Entry version 132 (16 Oct 2019)
Sequence version 2 (26 Jun 2007)
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Protein

Mitochondrial coenzyme A transporter SLC25A42

Gene

SLC25A42

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3',5'-diphosphate.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTransport

Protein family/group databases

Transport Classification Database

More...
TCDBi
2.A.29.12.2 the mitochondrial carrier (mc) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Mitochondrial coenzyme A transporter SLC25A42
Alternative name(s):
Solute carrier family 25 member 42
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:28380 SLC25A42

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
610823 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q86VD7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei33 – 53Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei89 – 109Helical; Name=2Sequence analysisAdd BLAST21
Transmembranei135 – 155Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei186 – 206Helical; Name=4Sequence analysisAdd BLAST21
Transmembranei230 – 250Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei293 – 313Helical; Name=6Sequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Metabolic crises, recurrent, with variable encephalomyopathic features and neurologic regression (MECREN)4 Publications
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionAn autosomal recessive disease characterized by muscle weakness, developmental delay, lactic acidosis, and encephalopathy. The severity of the clinical manifestations is highly variable even within affected individuals of the same family, ranging from asymptomatic lactic acidosis to severe developmental regression, epilepsy, intellectual disability, metabolic crisis, and multiorgan involvement.
Related information in OMIM
Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_082152291N → D in MECREN; loss-of-function variant unable to rescue motor deficiencies in zebrafish morphants. 4 Publications1

Keywords - Diseasei

Disease mutation

Organism-specific databases

DisGeNET

More...
DisGeNETi
284439

MalaCards human disease database

More...
MalaCardsi
SLC25A42
MIMi618416 phenotype

Open Targets

More...
OpenTargetsi
ENSG00000181035

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162403703

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q86VD7

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SLC25A42

Domain mapping of disease mutations (DMDM)

More...
DMDMi
150416122

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002923361 – 318Mitochondrial coenzyme A transporter SLC25A42Add BLAST318

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q86VD7

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q86VD7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q86VD7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q86VD7

PeptideAtlas

More...
PeptideAtlasi
Q86VD7

PRoteomics IDEntifications database

More...
PRIDEi
Q86VD7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
69988

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q86VD7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q86VD7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000181035 Expressed in 183 organ(s), highest expression level in right lobe of liver

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q86VD7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q86VD7 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA049449

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
129877, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q86VD7, 6 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000326693

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q86VD7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati31 – 117Solcar 1Add BLAST87
Repeati129 – 214Solcar 2Add BLAST86
Repeati224 – 312Solcar 3Add BLAST89

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0752 Eukaryota
ENOG410ZRF1 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158163

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000165726

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q86VD7

KEGG Orthology (KO)

More...
KOi
K15085

Identification of Orthologs from Complete Genome Data

More...
OMAi
WRGFYVG

Database of Orthologous Groups

More...
OrthoDBi
1253450at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q86VD7

TreeFam database of animal gene trees

More...
TreeFami
TF314806

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.50.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR014762 DNA_mismatch_repair_CS
IPR002167 Graves_DC
IPR002067 Mit_carrier
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00153 Mito_carr, 3 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00928 GRAVESDC
PR00926 MITOCARRIER

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103506 SSF103506, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50920 SOLCAR, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q86VD7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGNGVKEGPV RLHEDAEAVL SSSVSSKRDH RQVLSSLLSG ALAGALAKTA
60 70 80 90 100
VAPLDRTKII FQVSSKRFSA KEAFRVLYYT YLNEGFLSLW RGNSATMVRV
110 120 130 140 150
VPYAAIQFSA HEEYKRILGS YYGFRGEALP PWPRLFAGAL AGTTAASLTY
160 170 180 190 200
PLDLVRARMA VTPKEMYSNI FHVFIRISRE EGLKTLYHGF MPTVLGVIPY
210 220 230 240 250
AGLSFFTYET LKSLHREYSG RRQPYPFERM IFGACAGLIG QSASYPLDVV
260 270 280 290 300
RRRMQTAGVT GYPRASIART LRTIVREEGA VRGLYKGLSM NWVKGPIAVG
310
ISFTTFDLMQ ILLRHLQS
Length:318
Mass (Da):35,409
Last modified:June 26, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD42F26C200D3EACF
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAC02758 differs from that shown. Reason: Erroneous gene model prediction.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_03297039S → P1 PublicationCorresponds to variant dbSNP:rs17854359Ensembl.1
Natural variantiVAR_082152291N → D in MECREN; loss-of-function variant unable to rescue motor deficiencies in zebrafish morphants. 4 Publications1
Natural variantiVAR_032971312L → M2 PublicationsCorresponds to variant dbSNP:rs17854358Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
FN356975 mRNA Translation: CAX94853.1
AC002126 Genomic DNA Translation: AAB86983.1
AC004143 Genomic DNA Translation: AAC02758.1 Sequence problems.
BC045598 mRNA Translation: AAH45598.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS32966.1

NCBI Reference Sequences

More...
RefSeqi
NP_001308473.1, NM_001321544.1
NP_848621.2, NM_178526.4
XP_005259918.1, XM_005259861.3
XP_011526239.1, XM_011527937.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000318596; ENSP00000326693; ENSG00000181035

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
284439

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:284439

UCSC genome browser

More...
UCSCi
uc002nlf.5 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN356975 mRNA Translation: CAX94853.1
AC002126 Genomic DNA Translation: AAB86983.1
AC004143 Genomic DNA Translation: AAC02758.1 Sequence problems.
BC045598 mRNA Translation: AAH45598.1
CCDSiCCDS32966.1
RefSeqiNP_001308473.1, NM_001321544.1
NP_848621.2, NM_178526.4
XP_005259918.1, XM_005259861.3
XP_011526239.1, XM_011527937.2

3D structure databases

SMRiQ86VD7
ModBaseiSearch...

Protein-protein interaction databases

BioGridi129877, 2 interactors
IntActiQ86VD7, 6 interactors
STRINGi9606.ENSP00000326693

Protein family/group databases

TCDBi2.A.29.12.2 the mitochondrial carrier (mc) family

PTM databases

iPTMnetiQ86VD7
PhosphoSitePlusiQ86VD7

Polymorphism and mutation databases

BioMutaiSLC25A42
DMDMi150416122

Proteomic databases

jPOSTiQ86VD7
MassIVEiQ86VD7
MaxQBiQ86VD7
PaxDbiQ86VD7
PeptideAtlasiQ86VD7
PRIDEiQ86VD7
ProteomicsDBi69988

Genome annotation databases

EnsembliENST00000318596; ENSP00000326693; ENSG00000181035
GeneIDi284439
KEGGihsa:284439
UCSCiuc002nlf.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
284439
DisGeNETi284439

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SLC25A42
HGNCiHGNC:28380 SLC25A42
HPAiHPA049449
MalaCardsiSLC25A42
MIMi610823 gene
618416 phenotype
neXtProtiNX_Q86VD7
OpenTargetsiENSG00000181035
PharmGKBiPA162403703

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0752 Eukaryota
ENOG410ZRF1 LUCA
GeneTreeiENSGT00940000158163
HOGENOMiHOG000165726
InParanoidiQ86VD7
KOiK15085
OMAiWRGFYVG
OrthoDBi1253450at2759
PhylomeDBiQ86VD7
TreeFamiTF314806

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
SLC25A42 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
284439
PharosiQ86VD7

Protein Ontology

More...
PROi
PR:Q86VD7

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000181035 Expressed in 183 organ(s), highest expression level in right lobe of liver
ExpressionAtlasiQ86VD7 baseline and differential
GenevisibleiQ86VD7 HS

Family and domain databases

Gene3Di1.50.40.10, 1 hit
InterProiView protein in InterPro
IPR014762 DNA_mismatch_repair_CS
IPR002167 Graves_DC
IPR002067 Mit_carrier
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
PfamiView protein in Pfam
PF00153 Mito_carr, 3 hits
PRINTSiPR00928 GRAVESDC
PR00926 MITOCARRIER
SUPFAMiSSF103506 SSF103506, 1 hit
PROSITEiView protein in PROSITE
PS50920 SOLCAR, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS2542_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86VD7
Secondary accession number(s): D2T2J5, O14553, O43378
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: June 26, 2007
Last modified: October 16, 2019
This is version 132 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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