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Entry version 138 (02 Jun 2021)
Sequence version 2 (24 Nov 2009)
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Protein

MORC family CW-type zinc finger protein 1

Gene

MORC1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for spermatogenesis (By similarity).

Essential for de novo DNA methylation and silencing of transposable elements in the male embryonic germ cells (By similarity).

By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi486ZincPROSITE-ProRule annotation1
Metal bindingi489ZincPROSITE-ProRule annotation1
Metal bindingi512ZincPROSITE-ProRule annotation1
Metal bindingi523ZincPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri477 – 531CW-typePROSITE-ProRule annotationAdd BLAST55

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein
Biological processDifferentiation, RNA-mediated gene silencing, Spermatogenesis
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q86VD1

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
MORC family CW-type zinc finger protein 1
Alternative name(s):
Cancer/testis antigen 33
Short name:
CT33
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MORC1Imported
Synonyms:MORCImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:7198, MORC1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
603205, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q86VD1

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000114487.9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
27136

Open Targets

More...
OpenTargetsi
ENSG00000114487

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA30906

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q86VD1, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MORC1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
269849621

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002482411 – 984MORC family CW-type zinc finger protein 1Add BLAST984

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q86VD1

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q86VD1

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q86VD1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q86VD1

PeptideAtlas

More...
PeptideAtlasi
Q86VD1

PRoteomics IDEntifications database

More...
PRIDEi
Q86VD1

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
17870
69986 [Q86VD1-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q86VD1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q86VD1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000114487, Expressed in testis and 27 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q86VD1, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000114487, Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
118026, 8 interactors

Protein interaction database and analysis system

More...
IntActi
Q86VD1, 4 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000232603

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q86VD1, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q86VD1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili284 – 353Sequence analysisAdd BLAST70
Coiled coili737 – 761Sequence analysisAdd BLAST25
Coiled coili900 – 934Sequence analysisAdd BLAST35

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri477 – 531CW-typePROSITE-ProRule annotationAdd BLAST55

Keywords - Domaini

Coiled coil, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1845, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153998

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_011516_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q86VD1

Identification of Orthologs from Complete Genome Data

More...
OMAi
QAKRVQT

Database of Orthologous Groups

More...
OrthoDBi
193855at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q86VD1

TreeFam database of animal gene trees

More...
TreeFami
TF329118

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.565.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036890, HATPase_C_sf
IPR041006, Morc_S5
IPR011124, Znf_CW

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF17942, Morc6_S5, 1 hit
PF07496, zf-CW, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF55874, SSF55874, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51050, ZF_CW, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q86VD1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDDRYPALQR AQLRLDFIHA NSTTHSFLFG ALAELLDNAR DAGAERLDVF
60 70 80 90 100
SVDNEKLQGG FMLCFLDDGC GMSPEEASDI IYFGRSKKRL STLKFIGQYG
110 120 130 140 150
NGLKSGSMRI GKDFILFTKK EETMTCVFFS QTFCEEESLS EVVVPMPSWL
160 170 180 190 200
IRTRESVTDD PQKFAMELSI IYKYSPFKTE AELMQQFDVI YGKCGTLLVI
210 220 230 240 250
YNLKLLLNGE PELDVKTDKE DILMAGALED FPARWSFRAY TSVLYFNPWM
260 270 280 290 300
RIFIQAKRVK TKHLCYCLYR PRKYLYVTSS FKGAFKDEVK KAEEAVKIAE
310 320 330 340 350
SILKEAQIKV NQCDRTSLSS AKDVLQRALE DVEAKQKNLK EKQRELKTAR
360 370 380 390 400
TLSLFYGVNV ENRSQAGMFI YSNNRLIKMH EKVGSQLKLK SLLGAGVVGI
410 420 430 440 450
VNIPLEVMEP SHNKQEFLNV QEYNHLLKVM GQYLVQYCKD TGINNRNLTL
460 470 480 490 500
FCNEFGYQND IDVEKPLNSF QYQRRQAMGI PFIIQCDLCL KWRVLPSSTN
510 520 530 540 550
YQEKEFFDIW ICANNPNRLE NSCHQVECLP SIPLGTMSTI SPSKNEKEKQ
560 570 580 590 600
LRESVIKYQN RLAEQQPQPQ FIPVDEITVT STCLTSAHKE NTKTQKIRLL
610 620 630 640 650
GDDLKHESLS SFELSASRRG QKRNIEETDS DVEYISETKI MKKSMEEKMN
660 670 680 690 700
SQQQRIPVAL PENVKLAERS QRSQIANITT VWRAQPTEGC LKNAQAASWE
710 720 730 740 750
MKRKQSLNFV EECKVLTEDE NTSDSDIILV SDKSNTDVSL KQEKKEIPLL
760 770 780 790 800
NQEKQELCND VLAMKRSSSL PSWKSLLNVP MEDVNLSSGH IARVSVSGSC
810 820 830 840 850
KVASSPASSQ STPVKETVRK LKSKLREILL YFFPEHQLPS ELEEPALSCE
860 870 880 890 900
LEQCPEQMNK KLKMCFNQIQ NTYMVQYEKK IKRKLQSIIY DSNTRGIHNE
910 920 930 940 950
ISLGQCENKR KISEDKLKNL RIKLALLLQK LQLGGPEGDL EQTDTYLEAL
960 970 980
LKEDNLLFQN NLNKVTIDAR HRLPLEKNEK TSEN
Length:984
Mass (Da):112,881
Last modified:November 24, 2009 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i613163D31E2317A6
GO
Isoform 2 (identifier: Q86VD1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     569-589: Missing.

Show »
Length:963
Mass (Da):110,612
Checksum:i2FC5A04E37E5C650
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti65F → C in BAG63883 (PubMed:14702039).Curated1
Sequence conflicti692K → E in BAG63883 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_051188153T → P. Corresponds to variant dbSNP:rs35282274Ensembl.1
Natural variantiVAR_051189322K → M. Corresponds to variant dbSNP:rs17225637EnsemblClinVar.1
Natural variantiVAR_059698462D → E. Corresponds to variant dbSNP:rs3762696Ensembl.1
Natural variantiVAR_051190470F → I4 PublicationsCorresponds to variant dbSNP:rs4855576Ensembl.1
Natural variantiVAR_051191478M → V. Corresponds to variant dbSNP:rs3762697Ensembl.1
Natural variantiVAR_051192649M → I. Corresponds to variant dbSNP:rs35421732Ensembl.1
Natural variantiVAR_051193767S → N. Corresponds to variant dbSNP:rs2290057Ensembl.1
Natural variantiVAR_051194836H → Y3 PublicationsCorresponds to variant dbSNP:rs2593943Ensembl.1
Natural variantiVAR_051195982S → C. Corresponds to variant dbSNP:rs16855035Ensembl.1
Natural variantiVAR_051196982S → W. Corresponds to variant dbSNP:rs16855035Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_055495569 – 589Missing in isoform 2. 1 PublicationAdd BLAST21

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF084946 mRNA Translation: AAD43004.1
AK302642 mRNA Translation: BAG63883.1
AC016948 Genomic DNA No translation available.
AC112138 Genomic DNA No translation available.
BC050307 mRNA Translation: AAH50307.1
AL353955 mRNA Translation: CAB89255.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS2955.1 [Q86VD1-1]

Protein sequence database of the Protein Information Resource

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PIRi
T48690

NCBI Reference Sequences

More...
RefSeqi
NP_055244.3, NM_014429.3 [Q86VD1-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000232603; ENSP00000232603; ENSG00000114487 [Q86VD1-1]
ENST00000483760; ENSP00000417282; ENSG00000114487 [Q86VD1-2]

Database of genes from NCBI RefSeq genomes

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GeneIDi
27136

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:27136

UCSC genome browser

More...
UCSCi
uc003dxl.4, human [Q86VD1-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF084946 mRNA Translation: AAD43004.1
AK302642 mRNA Translation: BAG63883.1
AC016948 Genomic DNA No translation available.
AC112138 Genomic DNA No translation available.
BC050307 mRNA Translation: AAH50307.1
AL353955 mRNA Translation: CAB89255.1
CCDSiCCDS2955.1 [Q86VD1-1]
PIRiT48690
RefSeqiNP_055244.3, NM_014429.3 [Q86VD1-1]

3D structure databases

SMRiQ86VD1
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi118026, 8 interactors
IntActiQ86VD1, 4 interactors
STRINGi9606.ENSP00000232603

PTM databases

iPTMnetiQ86VD1
PhosphoSitePlusiQ86VD1

Genetic variation databases

BioMutaiMORC1
DMDMi269849621

Proteomic databases

jPOSTiQ86VD1
MassIVEiQ86VD1
MaxQBiQ86VD1
PaxDbiQ86VD1
PeptideAtlasiQ86VD1
PRIDEiQ86VD1
ProteomicsDBi17870
69986 [Q86VD1-1]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
32406, 119 antibodies

The DNASU plasmid repository

More...
DNASUi
27136

Genome annotation databases

EnsembliENST00000232603; ENSP00000232603; ENSG00000114487 [Q86VD1-1]
ENST00000483760; ENSP00000417282; ENSG00000114487 [Q86VD1-2]
GeneIDi27136
KEGGihsa:27136
UCSCiuc003dxl.4, human [Q86VD1-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
27136
DisGeNETi27136

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MORC1
HGNCiHGNC:7198, MORC1
HPAiENSG00000114487, Tissue enriched (testis)
MIMi603205, gene
neXtProtiNX_Q86VD1
OpenTargetsiENSG00000114487
PharmGKBiPA30906
VEuPathDBiHostDB:ENSG00000114487.9

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1845, Eukaryota
GeneTreeiENSGT00940000153998
HOGENOMiCLU_011516_0_1_1
InParanoidiQ86VD1
OMAiQAKRVQT
OrthoDBi193855at2759
PhylomeDBiQ86VD1
TreeFamiTF329118

Enzyme and pathway databases

PathwayCommonsiQ86VD1

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
27136, 6 hits in 981 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
MORC1, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
27136
PharosiQ86VD1, Tbio

Protein Ontology

More...
PROi
PR:Q86VD1
RNActiQ86VD1, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000114487, Expressed in testis and 27 other tissues
GenevisibleiQ86VD1, HS

Family and domain databases

Gene3Di3.30.565.10, 1 hit
InterProiView protein in InterPro
IPR036890, HATPase_C_sf
IPR041006, Morc_S5
IPR011124, Znf_CW
PfamiView protein in Pfam
PF17942, Morc6_S5, 1 hit
PF07496, zf-CW, 1 hit
SUPFAMiSSF55874, SSF55874, 1 hit
PROSITEiView protein in PROSITE
PS51050, ZF_CW, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMORC1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86VD1
Secondary accession number(s): B4DYX1
, E7ERX1, Q7L8E2, Q9NSG7, Q9Y6D4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: November 24, 2009
Last modified: June 2, 2021
This is version 138 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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