Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 147 (13 Feb 2019)
Sequence version 2 (16 Dec 2008)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

Zinc finger protein 429

Gene

ZNF429

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri145 – 167C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri173 – 195C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri201 – 223C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri229 – 251C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri257 – 279C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri285 – 307C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri313 – 335C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri341 – 363C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri369 – 391C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri397 – 419C2H2-type 10; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri425 – 447C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri453 – 475C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri481 – 503C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri509 – 531C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri537 – 559C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri565 – 587C2H2-type 16PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri593 – 615C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri621 – 643C2H2-type 18PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436 Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 429
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF429
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000197013.9

Human Gene Nomenclature Database

More...
HGNCi
HGNC:20817 ZNF429

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q86V71

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
353088

Open Targets

More...
OpenTargetsi
ENSG00000197013

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134910790

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF429

Domain mapping of disease mutations (DMDM)

More...
DMDMi
218511972

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000475771 – 674Zinc finger protein 429Add BLAST674

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei605PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q86V71

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q86V71

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q86V71

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q86V71

PeptideAtlas

More...
PeptideAtlasi
Q86V71

PRoteomics IDEntifications database

More...
PRIDEi
Q86V71

ProteomicsDB human proteome resource

More...
ProteomicsDBi
69972

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q86V71

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q86V71

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000197013 Expressed in 144 organ(s), highest expression level in C1 segment of cervical spinal cord

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q86V71 baseline and differential

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA004139

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000351280

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q86V71

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q86V71

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini4 – 75KRABPROSITE-ProRule annotationAdd BLAST72

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri145 – 167C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri173 – 195C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri201 – 223C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri229 – 251C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri257 – 279C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri285 – 307C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri313 – 335C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri341 – 363C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri369 – 391C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri397 – 419C2H2-type 10; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri425 – 447C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri453 – 475C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri481 – 503C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri509 – 531C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri537 – 559C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri565 – 587C2H2-type 16PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri593 – 615C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri621 – 643C2H2-type 18PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153165

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000234617

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG018163

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q86V71

KEGG Orthology (KO)

More...
KOi
K09228

Identification of Orthologs from Complete Genome Data

More...
OMAi
DEPPVIC

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q86V71

TreeFam database of animal gene trees

More...
TreeFami
TF342117

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765 KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 15 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 15 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 10 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 15 hits
PS50157 ZINC_FINGER_C2H2_2, 17 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q86V71-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGPLTFTDVA IEFSLEEWQC LDTAQQNLYR NVMLENYRNL VFLGIAVSKP
60 70 80 90 100
DLITCLEKEK EPCKMKRHEM VDEPPVVCSH FAEDFWPEQD IKDSFQKVTL
110 120 130 140 150
RRYDKRGHEN LQLRKGYKTV GDCKLYKGGY NGLNQCLTLT QSKMYHCDIY
160 170 180 190 200
VKVFYAFSNA DRYKTRHTGK KPFQCKKCGK SFCMLSQLTQ HKKIHIRENT
210 220 230 240 250
YRCKEFGNAF NQSSALTNHK RIYVGEKHYR CEECGKAFNH YSTLTNHKRI
260 270 280 290 300
HTGEKPYKCK ECGKAFSRYS TLTTHKRIHS GEKPYKCDEC GKTFSISSTF
310 320 330 340 350
TKHKIIHTEE KPYKCKECGK AFNRSSTLTS HKRIHTGEKP YKCEECGKAF
360 370 380 390 400
NWSSTLTKHK VIHTGEKPYK CEECGKAFNQ SSRLTRHKKI HTGEEPYKFE
410 420 430 440 450
KCGRVFTCSS TLTQDKKIHT GEKPYNCEEC GKVFTYSSTL TRHKRIHTEE
460 470 480 490 500
KPYKCNECGK AFNRSSHLTS HRRIHTGEKP YKCEECGKAF KQSSNLNSHK
510 520 530 540 550
KIHSGEKPYK CEECGKAFIL SSRLTQHKKI HTGEKPYKCE ECGKAFNRSS
560 570 580 590 600
RLTQHKKIHT GEKPYKCKQC DKAFTHSSNL SSHKKIHSGE KPYKCEECGK
610 620 630 640 650
AFNRSSRLTQ HKKIHTREKP YKCEECAKAF TRSSRLTQHK KIHRMGVVAH
660 670
ACNPSTLGGR GGRITRSGDR DRPG
Length:674
Mass (Da):78,152
Last modified:December 16, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC48BC76B58059FE7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WV98A0A087WV98_HUMAN
Zinc finger protein 429
ZNF429
585Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0QZ47M0QZ47_HUMAN
Zinc finger protein 429
ZNF429
122Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0QYC4M0QYC4_HUMAN
Zinc finger protein 429
ZNF429
93Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAK01422 differs from that shown.Curated
The sequence AAK01422 differs from that shown. Reason: Frameshift at several positions.Curated
The sequence AAP30884 differs from that shown.Curated
The sequence AAP30884 differs from that shown. Reason: Frameshift at several positions.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti167H → Y in AAP30884 (Ref. 2) Curated1
Sequence conflicti167H → Y in AAK01422 (PubMed:7865130).Curated1
Sequence conflicti206 – 207FG → CC in AAP30884 (Ref. 2) Curated2
Sequence conflicti206 – 207FG → CC in AAK01422 (PubMed:7865130).Curated2
Sequence conflicti249 – 276Missing in AAP30884 (Ref. 2) CuratedAdd BLAST28
Sequence conflicti249 – 276Missing in AAK01422 (PubMed:7865130).CuratedAdd BLAST28
Sequence conflicti252T → S in AAP30884 (Ref. 2) Curated1
Sequence conflicti252T → S in AAK01422 (PubMed:7865130).Curated1
Sequence conflicti337G → V in AAP30884 (Ref. 2) Curated1
Sequence conflicti337G → V in AAK01422 (PubMed:7865130).Curated1
Sequence conflicti361V → I in AAP30884 (Ref. 2) Curated1
Sequence conflicti361V → I in AAK01422 (PubMed:7865130).Curated1
Sequence conflicti367K → N in AAK01422 (PubMed:7865130).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_047848650H → Y. Corresponds to variant dbSNP:rs2562473Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC010615 Genomic DNA No translation available.
AY269786 mRNA Translation: AAP30884.1 Sequence problems.
AF325191 mRNA Translation: AAK01422.1 Sequence problems.
BM996292 mRNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS42537.1

NCBI Reference Sequences

More...
RefSeqi
NP_001001415.2, NM_001001415.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.572567
Hs.659553
Hs.709598

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000358491; ENSP00000351280; ENSG00000197013

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
353088

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:353088

UCSC genome browser

More...
UCSCi
uc002nqd.2 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010615 Genomic DNA No translation available.
AY269786 mRNA Translation: AAP30884.1 Sequence problems.
AF325191 mRNA Translation: AAK01422.1 Sequence problems.
BM996292 mRNA No translation available.
CCDSiCCDS42537.1
RefSeqiNP_001001415.2, NM_001001415.3
UniGeneiHs.572567
Hs.659553
Hs.709598

3D structure databases

ProteinModelPortaliQ86V71
SMRiQ86V71
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000351280

PTM databases

iPTMnetiQ86V71
PhosphoSitePlusiQ86V71

Polymorphism and mutation databases

BioMutaiZNF429
DMDMi218511972

Proteomic databases

EPDiQ86V71
jPOSTiQ86V71
MaxQBiQ86V71
PaxDbiQ86V71
PeptideAtlasiQ86V71
PRIDEiQ86V71
ProteomicsDBi69972

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000358491; ENSP00000351280; ENSG00000197013
GeneIDi353088
KEGGihsa:353088
UCSCiuc002nqd.2 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
353088
DisGeNETi353088
EuPathDBiHostDB:ENSG00000197013.9

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF429
HGNCiHGNC:20817 ZNF429
HPAiHPA004139
neXtProtiNX_Q86V71
OpenTargetsiENSG00000197013
PharmGKBiPA134910790

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000153165
HOGENOMiHOG000234617
HOVERGENiHBG018163
InParanoidiQ86V71
KOiK09228
OMAiDEPPVIC
OrthoDBi1318335at2759
PhylomeDBiQ86V71
TreeFamiTF342117

Enzyme and pathway databases

ReactomeiR-HSA-212436 Generic Transcription Pathway

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ZNF429 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
353088

Protein Ontology

More...
PROi
PR:Q86V71

Gene expression databases

BgeeiENSG00000197013 Expressed in 144 organ(s), highest expression level in C1 segment of cervical spinal cord
ExpressionAtlasiQ86V71 baseline and differential

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 15 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 15 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 10 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 15 hits
PS50157 ZINC_FINGER_C2H2_2, 17 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN429_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86V71
Secondary accession number(s): A6NLV7, Q9BZE6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2003
Last sequence update: December 16, 2008
Last modified: February 13, 2019
This is version 147 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again