Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
The new UniProt website is here! Take me to UniProt BETA

UniProtKB - Q86V71 (ZN429_HUMAN)

Entry version 164 (25 May 2022)
Sequence version 2 (16 Dec 2008)
Previous versions | rss
Add a publicationFeedback
Protein

Zinc finger protein 429

Gene

ZNF429

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri145 – 167C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri173 – 195C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri201 – 223C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri229 – 251C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri257 – 279C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri285 – 307C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri313 – 335C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri341 – 363C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri369 – 391C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri397 – 419C2H2-type 10; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri425 – 447C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri453 – 475C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri481 – 503C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri509 – 531C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri537 – 559C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri565 – 587C2H2-type 16PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri593 – 615C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri621 – 643C2H2-type 18PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q86V71

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-212436, Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 429
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF429
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:20817, ZNF429

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q86V71

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000197013

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		353088

Open Targets

More...OpenTargetsi		ENSG00000197013

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134910790

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q86V71, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZNF429

Domain mapping of disease mutations (DMDM)

More...DMDMi		218511972

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000475771 – 674Zinc finger protein 429Add BLAST674

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei605PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q86V71

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q86V71

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q86V71

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q86V71

PeptideAtlas

More...PeptideAtlasi		Q86V71

PRoteomics IDEntifications database

More...PRIDEi		Q86V71

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q86V71

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q86V71

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000197013, Expressed in C1 segment of cervical spinal cord and 161 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q86V71, baseline and differential

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000197013, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000351280

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q86V71, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q86V71

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q86V71

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini4 – 75KRABPROSITE-ProRule annotationAdd BLAST72

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni653 – 674DisorderedSequence analysisAdd BLAST22

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri145 – 167C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri173 – 195C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri201 – 223C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri229 – 251C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri257 – 279C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri285 – 307C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri313 – 335C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri341 – 363C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri369 – 391C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri397 – 419C2H2-type 10; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri425 – 447C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri453 – 475C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri481 – 503C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri509 – 531C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri537 – 559C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri565 – 587C2H2-type 16PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri593 – 615C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri621 – 643C2H2-type 18PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000153165

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_002678_44_5_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q86V71

Identification of Orthologs from Complete Genome Data

More...OMAi		CKKCFAD

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q86V71

TreeFam database of animal gene trees

More...TreeFami		TF342117

Family and domain databases

Conserved Domains Database

More...CDDi		cd07765, KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 15 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 15 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 10 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 15 hits
PS50157, ZINC_FINGER_C2H2_2, 17 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q86V71-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGPLTFTDVA IEFSLEEWQC LDTAQQNLYR NVMLENYRNL VFLGIAVSKP 
        60         70         80         90        100
DLITCLEKEK EPCKMKRHEM VDEPPVVCSH FAEDFWPEQD IKDSFQKVTL 
       110        120        130        140        150
RRYDKRGHEN LQLRKGYKTV GDCKLYKGGY NGLNQCLTLT QSKMYHCDIY 
       160        170        180        190        200
VKVFYAFSNA DRYKTRHTGK KPFQCKKCGK SFCMLSQLTQ HKKIHIRENT 
       210        220        230        240        250
YRCKEFGNAF NQSSALTNHK RIYVGEKHYR CEECGKAFNH YSTLTNHKRI 
       260        270        280        290        300
HTGEKPYKCK ECGKAFSRYS TLTTHKRIHS GEKPYKCDEC GKTFSISSTF 
       310        320        330        340        350
TKHKIIHTEE KPYKCKECGK AFNRSSTLTS HKRIHTGEKP YKCEECGKAF 
       360        370        380        390        400
NWSSTLTKHK VIHTGEKPYK CEECGKAFNQ SSRLTRHKKI HTGEEPYKFE 
       410        420        430        440        450
KCGRVFTCSS TLTQDKKIHT GEKPYNCEEC GKVFTYSSTL TRHKRIHTEE 
       460        470        480        490        500
KPYKCNECGK AFNRSSHLTS HRRIHTGEKP YKCEECGKAF KQSSNLNSHK 
       510        520        530        540        550
KIHSGEKPYK CEECGKAFIL SSRLTQHKKI HTGEKPYKCE ECGKAFNRSS 
       560        570        580        590        600
RLTQHKKIHT GEKPYKCKQC DKAFTHSSNL SSHKKIHSGE KPYKCEECGK 
       610        620        630        640        650
AFNRSSRLTQ HKKIHTREKP YKCEECAKAF TRSSRLTQHK KIHRMGVVAH 
       660        670 
ACNPSTLGGR GGRITRSGDR DRPG
Length:674
Mass (Da):78,152
Last modified:December 16, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC48BC76B58059FE7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0QZ47M0QZ47_HUMAN
Zinc finger protein 429
ZNF429
122Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0QYC4M0QYC4_HUMAN
Zinc finger protein 429
ZNF429
93Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAK01422 differs from that shown.Curated
The sequence AAK01422 differs from that shown. Reason: Frameshift.Curated
The sequence AAP30884 differs from that shown.Curated
The sequence AAP30884 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti167H → Y in AAP30884 (Ref. 2) Curated1
Sequence conflicti167H → Y in AAK01422 (PubMed:7865130).Curated1
Sequence conflicti206 – 207FG → CC in AAP30884 (Ref. 2) Curated2
Sequence conflicti206 – 207FG → CC in AAK01422 (PubMed:7865130).Curated2
Sequence conflicti249 – 276Missing in AAP30884 (Ref. 2) CuratedAdd BLAST28
Sequence conflicti249 – 276Missing in AAK01422 (PubMed:7865130).CuratedAdd BLAST28
Sequence conflicti252T → S in AAP30884 (Ref. 2) Curated1
Sequence conflicti252T → S in AAK01422 (PubMed:7865130).Curated1
Sequence conflicti337G → V in AAP30884 (Ref. 2) Curated1
Sequence conflicti337G → V in AAK01422 (PubMed:7865130).Curated1
Sequence conflicti361V → I in AAP30884 (Ref. 2) Curated1
Sequence conflicti361V → I in AAK01422 (PubMed:7865130).Curated1
Sequence conflicti367K → N in AAK01422 (PubMed:7865130).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_047848650H → Y. Corresponds to variant dbSNP:rs2562473Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AC010615 Genomic DNA No translation available.
AY269786 mRNA Translation: AAP30884.1 Sequence problems.
AF325191 mRNA Translation: AAK01422.1 Sequence problems.
BM996292 mRNA No translation available.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS42537.1

NCBI Reference Sequences

More...RefSeqi		NP_001001415.2, NM_001001415.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000358491.9; ENSP00000351280.3; ENSG00000197013.11

Database of genes from NCBI RefSeq genomes

More...GeneIDi		353088

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:353088

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000358491.9; ENSP00000351280.3; NM_001001415.4; NP_001001415.2

UCSC genome browser

More...UCSCi		uc002nqd.2, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010615 Genomic DNA No translation available.
AY269786 mRNA Translation: AAP30884.1 Sequence problems.
AF325191 mRNA Translation: AAK01422.1 Sequence problems.
BM996292 mRNA No translation available.
CCDSiCCDS42537.1
RefSeqiNP_001001415.2, NM_001001415.3

3D structure databases

AlphaFoldDBiQ86V71
SMRiQ86V71
ModBaseiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000351280

PTM databases

iPTMnetiQ86V71
PhosphoSitePlusiQ86V71

Genetic variation databases

BioMutaiZNF429
DMDMi218511972

Proteomic databases

jPOSTiQ86V71
MassIVEiQ86V71
MaxQBiQ86V71
PaxDbiQ86V71
PeptideAtlasiQ86V71
PRIDEiQ86V71

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		44155, 70 antibodies from 13 providers

The DNASU plasmid repository

More...DNASUi		353088

Genome annotation databases

EnsembliENST00000358491.9; ENSP00000351280.3; ENSG00000197013.11
GeneIDi353088
KEGGihsa:353088
MANE-SelectiENST00000358491.9; ENSP00000351280.3; NM_001001415.4; NP_001001415.2
UCSCiuc002nqd.2, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		353088
DisGeNETi353088

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZNF429
HGNCiHGNC:20817, ZNF429
HPAiENSG00000197013, Low tissue specificity
neXtProtiNX_Q86V71
OpenTargetsiENSG00000197013
PharmGKBiPA134910790
VEuPathDBiHostDB:ENSG00000197013

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000153165
HOGENOMiCLU_002678_44_5_1
InParanoidiQ86V71
OMAiCKKCFAD
OrthoDBi1318335at2759
PhylomeDBiQ86V71
TreeFamiTF342117

Enzyme and pathway databases

PathwayCommonsiQ86V71
ReactomeiR-HSA-212436, Generic Transcription Pathway

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		353088, 38 hits in 1035 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ZNF429, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		353088
PharosiQ86V71, Tdark

Protein Ontology

More...PROi		PR:Q86V71
RNActiQ86V71, protein

Gene expression databases

BgeeiENSG00000197013, Expressed in C1 segment of cervical spinal cord and 161 other tissues
ExpressionAtlasiQ86V71, baseline and differential

Family and domain databases

CDDicd07765, KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 15 hits
SMARTiView protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 15 hits
SUPFAMiSSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 10 hits
PROSITEiView protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 15 hits
PS50157, ZINC_FINGER_C2H2_2, 17 hits

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN429_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86V71
Secondary accession number(s): A6NLV7, Q9BZE6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2003
Last sequence update: December 16, 2008
Last modified: May 25, 2022
This is version 164 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again