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Entry version 139 (22 Apr 2020)
Sequence version 2 (16 May 2006)
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Protein

Leucine zipper protein 1

Gene

LUZP1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Leucine zipper protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LUZP1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:14985 LUZP1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
601422 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q86V48

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
7798

Open Targets

More...
OpenTargetsi
ENSG00000169641

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA30487

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q86V48 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
LUZP1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
97072093

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources1 Publication
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002345502 – 1076Leucine zipper protein 1Add BLAST1075

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineCombined sources1 Publication1
Modified residuei255PhosphoserineCombined sources1
Modified residuei394PhosphoserineCombined sources1
Modified residuei425PhosphoserineCombined sources1
Modified residuei440PhosphoserineCombined sources1
Modified residuei512PhosphoserineCombined sources1
Modified residuei570PhosphoserineCombined sources1
Modified residuei574PhosphoserineCombined sources1
Modified residuei611PhosphoserineCombined sources1
Modified residuei659PhosphoserineCombined sources1
Modified residuei679PhosphothreonineCombined sources1
Modified residuei690PhosphoserineCombined sources1
Modified residuei745PhosphoserineCombined sources1
Modified residuei905PhosphoserineCombined sources1
Modified residuei932PhosphoserineCombined sources1
Modified residuei958PhosphothreonineCombined sources1
Modified residuei995PhosphoserineCombined sources1
Modified residuei1042PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q86V48

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q86V48

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q86V48

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q86V48

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q86V48

PeptideAtlas

More...
PeptideAtlasi
Q86V48

PRoteomics IDEntifications database

More...
PRIDEi
Q86V48

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
69966 [Q86V48-1]
69967 [Q86V48-2]
69968 [Q86V48-3]

PTM databases

CarbonylDB database of protein carbonylation sites

More...
CarbonylDBi
Q86V48

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q86V48

MetOSite database of methionine sulfoxide sites

More...
MetOSitei
Q86V48

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q86V48

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000169641 Expressed in tendon of biceps brachii and 236 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q86V48 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q86V48 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000169641 Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
113574, 99 interactors

Database of interacting proteins

More...
DIPi
DIP-33113N

Protein interaction database and analysis system

More...
IntActi
Q86V48, 78 interactors

Molecular INTeraction database

More...
MINTi
Q86V48

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000303758

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q86V48 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q86V48

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili11 – 359Sequence analysisAdd BLAST349

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IJB9 Eukaryota
ENOG410Y6B5 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182852

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_010207_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q86V48

Identification of Orthologs from Complete Genome Data

More...
OMAi
NHSAGTE

Database of Orthologous Groups

More...
OrthoDBi
176494at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q86V48

TreeFam database of animal gene trees

More...
TreeFami
TF331399

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR026734 Luzp1

The PANTHER Classification System

More...
PANTHERi
PTHR23166:SF7 PTHR23166:SF7, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q86V48-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAEFTSYKET ASSRHLRFKL QSLSRRLDEL EEATKNLQKA EDELLDLQDK
60 70 80 90 100
VIQAEGSNSS MLAEIEVLRQ RVLRIEGKDE EIKRAEDLCR LMKEKLEEEE
110 120 130 140 150
NLTRELKSEI ERLQKRMAEL EKLEEAFSRS KNDCTQLCLS LNEERNLTKK
160 170 180 190 200
ISSELEMLRV KVKELESSED RLDKTEQSLA SELEKLKSLT LSFVSERKYL
210 220 230 240 250
NEKEKENEKL IKELTQKLEQ NKKMNRDYTR NASNLERNDL RIEDGISSTL
260 270 280 290 300
PSKESRRKGG LDYLKQVENE TRNKSENEKN RNQEDNKVKD LNQEIEKLKT
310 320 330 340 350
QIKHFESLEE ELKKMKSKNN DLQDNYLSEQ NKNKLLASQL EEIKLQIKKQ
360 370 380 390 400
KELENGEVEG EDAFLSSKGR HERTKFRGHG SEASVSKHTA RELSPQHKRE
410 420 430 440 450
RLRNREFALN NENYSLSNRQ VSSPSFTNRR AAKASHMGVS TDSGTQETKK
460 470 480 490 500
TEDRFVPGSS QSEGKKSREQ PSVLSRYPPA AQEHSKAWKG TSKPGTESGL
510 520 530 540 550
KGKVEKTTRT FSDTTHGSVP SDPLGRADKA SDTSSETVFG KRGHVLGNGS
560 570 580 590 600
QVTQAANSGC SKAIGALASS RRSSSEGLSK GKKAANGLEA DNSCPNSKAP
610 620 630 640 650
VLSKYPYSCR SQENILQGFS TSHKEGVNQP AAVVMEDSSP HEALRCRVIK
660 670 680 690 700
SSGREKPDSD DDLDIASLVT AKLVNTTITP EPEPKPQPNS REKAKTRGAP
710 720 730 740 750
RTSLFENDKD AGMENESVKS VRASTNTMEL PDTNGAGVKS QRPFSPREAL
760 770 780 790 800
RSRAIIKPVI VDKDVKKIMG GSGTETTLEK QKPVSKPGPN KVTSSITIYP
810 820 830 840 850
SDSSSPRAAP GEALRERHTS TSNIQVGLAE LTSVSNHVSS PFELSIHKHD
860 870 880 890 900
ITLQLAEAER MADGPLKDRP ETVVSRSSII IKPSDPVERN SHAPPAETIR
910 920 930 940 950
WKSHSAPSEV GFSDARHVTV RNAWKSRRDL KSLEDPPTRI GKNVESTNSN
960 970 980 990 1000
AYTQRSSTDF SELEQPRSCL FEQGTRRVGP SSGDAPEPSS RRTQSSLTVS
1010 1020 1030 1040 1050
EVLTRRNRVG DTITVAAWNH SASMEEEGED CTLSVYRQLH NSLDPSELPG
1060 1070
KQGLPESGRV RAEERLRPTR PCAEEN
Length:1,076
Mass (Da):120,275
Last modified:May 16, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i682D8C008BE77F1A
GO
Isoform 2 (identifier: Q86V48-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1025-1025: E → SS
     1026-1076: Missing.

Show »
Length:1,026
Mass (Da):114,588
Checksum:iCC0F7FCB98E24787
GO
Isoform 3 (identifier: Q86V48-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1025-1025: E → VSSSLSPLSLFSLPFPSLPFPFSPLLWPV
     1026-1076: Missing.

Show »
Length:1,053
Mass (Da):117,555
Checksum:iAE160A5A76046E9C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E5RFK8E5RFK8_HUMAN
Leucine zipper protein 1
LUZP1
273Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RHU7E5RHU7_HUMAN
Leucine zipper protein 1
LUZP1
35Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH33219 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti25R → P in BAB84979 (PubMed:12693554).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_056932317S → A. Corresponds to variant dbSNP:rs12091554Ensembl.1
Natural variantiVAR_026283458G → S2 PublicationsCorresponds to variant dbSNP:rs477830Ensembl.1
Natural variantiVAR_026284461Q → K2 PublicationsCorresponds to variant dbSNP:rs3765407Ensembl.1
Natural variantiVAR_056933491T → I. Corresponds to variant dbSNP:rs35917050Ensembl.1
Natural variantiVAR_026285868D → N2 PublicationsCorresponds to variant dbSNP:rs10799790Ensembl.1
Natural variantiVAR_0569341034S → N. Corresponds to variant dbSNP:rs12066671Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0183511025E → SS in isoform 2. 1 Publication1
Alternative sequenceiVSP_0183521025E → VSSSLSPLSLFSLPFPSLPF PFSPLLWPV in isoform 3. 1 Publication1
Alternative sequenceiVSP_0183531026 – 1076Missing in isoform 2 and isoform 3. 2 PublicationsAdd BLAST51

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL031428 Genomic DNA No translation available.
BC033219 mRNA Translation: AAH33219.1 Different initiation.
BC051733 mRNA Translation: AAH51733.1
AK074153 mRNA Translation: BAB84979.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS30628.1 [Q86V48-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001136018.1, NM_001142546.1 [Q86V48-1]
NP_361013.3, NM_033631.3 [Q86V48-1]
XP_011540392.1, XM_011542090.2 [Q86V48-1]
XP_011540393.1, XM_011542091.2 [Q86V48-1]
XP_016857741.1, XM_017002252.1 [Q86V48-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000302291; ENSP00000303758; ENSG00000169641 [Q86V48-1]
ENST00000314174; ENSP00000313705; ENSG00000169641 [Q86V48-2]
ENST00000418342; ENSP00000393460; ENSG00000169641 [Q86V48-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
7798

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:7798

UCSC genome browser

More...
UCSCi
uc001bgl.4 human [Q86V48-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL031428 Genomic DNA No translation available.
BC033219 mRNA Translation: AAH33219.1 Different initiation.
BC051733 mRNA Translation: AAH51733.1
AK074153 mRNA Translation: BAB84979.1
CCDSiCCDS30628.1 [Q86V48-1]
RefSeqiNP_001136018.1, NM_001142546.1 [Q86V48-1]
NP_361013.3, NM_033631.3 [Q86V48-1]
XP_011540392.1, XM_011542090.2 [Q86V48-1]
XP_011540393.1, XM_011542091.2 [Q86V48-1]
XP_016857741.1, XM_017002252.1 [Q86V48-1]

3D structure databases

SMRiQ86V48
ModBaseiSearch...

Protein-protein interaction databases

BioGridi113574, 99 interactors
DIPiDIP-33113N
IntActiQ86V48, 78 interactors
MINTiQ86V48
STRINGi9606.ENSP00000303758

PTM databases

CarbonylDBiQ86V48
iPTMnetiQ86V48
MetOSiteiQ86V48
PhosphoSitePlusiQ86V48

Polymorphism and mutation databases

BioMutaiLUZP1
DMDMi97072093

Proteomic databases

EPDiQ86V48
jPOSTiQ86V48
MassIVEiQ86V48
MaxQBiQ86V48
PaxDbiQ86V48
PeptideAtlasiQ86V48
PRIDEiQ86V48
ProteomicsDBi69966 [Q86V48-1]
69967 [Q86V48-2]
69968 [Q86V48-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
30121 103 antibodies

The DNASU plasmid repository

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DNASUi
7798

Genome annotation databases

EnsembliENST00000302291; ENSP00000303758; ENSG00000169641 [Q86V48-1]
ENST00000314174; ENSP00000313705; ENSG00000169641 [Q86V48-2]
ENST00000418342; ENSP00000393460; ENSG00000169641 [Q86V48-1]
GeneIDi7798
KEGGihsa:7798
UCSCiuc001bgl.4 human [Q86V48-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
7798
DisGeNETi7798

GeneCards: human genes, protein and diseases

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GeneCardsi
LUZP1
HGNCiHGNC:14985 LUZP1
HPAiENSG00000169641 Low tissue specificity
MIMi601422 gene
neXtProtiNX_Q86V48
OpenTargetsiENSG00000169641
PharmGKBiPA30487

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG410IJB9 Eukaryota
ENOG410Y6B5 LUCA
GeneTreeiENSGT00950000182852
HOGENOMiCLU_010207_1_0_1
InParanoidiQ86V48
OMAiNHSAGTE
OrthoDBi176494at2759
PhylomeDBiQ86V48
TreeFamiTF331399

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
LUZP1 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
7798
PharosiQ86V48 Tdark

Protein Ontology

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PROi
PR:Q86V48
RNActiQ86V48 protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000169641 Expressed in tendon of biceps brachii and 236 other tissues
ExpressionAtlasiQ86V48 baseline and differential
GenevisibleiQ86V48 HS

Family and domain databases

InterProiView protein in InterPro
IPR026734 Luzp1
PANTHERiPTHR23166:SF7 PTHR23166:SF7, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLUZP1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86V48
Secondary accession number(s): Q5TH93, Q8N4X3, Q8TEH1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: May 16, 2006
Last modified: April 22, 2020
This is version 139 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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