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UniProtKB - Q86U90 (YRDC_HUMAN)

Entry version 136 (10 Feb 2021)
Sequence version 1 (01 Jun 2003)
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Protein

YrdC domain-containing protein, mitochondrial

Gene

YRDC

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May regulate the activity of some transporters.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q86U90

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
YrdC domain-containing protein, mitochondrial
Alternative name(s):
Dopamine receptor-interacting protein 3
Ischemia/reperfusion-inducible protein homolog
Short name:
hIRIP
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:YRDC
Synonyms:DRIP3, IRIP
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:28905, YRDC

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		612276, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q86U90

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000196449.3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane, Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		79693

Open Targets

More...OpenTargetsi		ENSG00000196449

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA142670553

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q86U90, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		YRDC

Domain mapping of disease mutations (DMDM)

More...DMDMi		74750410

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 55MitochondrionSequence analysisAdd BLAST55
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000034140256 – 279YrdC domain-containing protein, mitochondrialAdd BLAST224

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei60PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q86U90

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q86U90

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q86U90

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q86U90

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q86U90

PeptideAtlas

More...PeptideAtlasi		Q86U90

PRoteomics IDEntifications database

More...PRIDEi		Q86U90

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		69783

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		Q86U90, 1 site, 1 O-linked glycan (1 site)

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q86U90

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q86U90

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitously expressed.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000196449, Expressed in bone marrow and 214 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q86U90, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000196449, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with RSC1A1.

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		122814, 12 interactors

Protein interaction database and analysis system

More...IntActi		Q86U90, 7 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000362135

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q86U90, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q86U90

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini67 – 257YrdC-likePROSITE-ProRule annotationAdd BLAST191

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SUA5 family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3051, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000015364

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_031397_5_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q86U90

Identification of Orthologs from Complete Genome Data

More...OMAi		WHEQPLA

Database of Orthologous Groups

More...OrthoDBi		1027994at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q86U90

TreeFam database of animal gene trees

More...TreeFami		TF314358

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR017945, DHBP_synth_RibB-like_a/b_dom
IPR006070, YrdC-like_dom

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01300, Sua5_yciO_yrdC, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF55821, SSF55821, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00057, TIGR00057, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51163, YRDC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q86U90-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSPARRCRGM RAAVAASVGL SEGPAGSRSG RLFRPPSPAP AAPGARLLRL 
        60         70         80         90        100
PGSGAVQAAS PERAGWTEAL RAAVAELRAG AVVAVPTDTL YGLACAASCS 
       110        120        130        140        150
AALRAVYRLK GRSEAKPLAV CLGRVADVYR YCRVRVPEGL LKDLLPGPVT 
       160        170        180        190        200
LVMERSEELN KDLNPFTPLV GIRIPDHAFM QDLAQMFEGP LALTSANLSS 
       210        220        230        240        250
QASSLNVEEF QDLWPQLSLV IDGGQIGDGQ SPECRLGSTV VDLSVPGKFG 
       260        270 
IIRPGCALES TTAILQQKYG LLPSHASYL
Length:279
Mass (Da):29,328
Last modified:June 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF8F5C30274E2BB12
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH08984 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAP37053 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAP37054 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAB15668 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AY172561 mRNA Translation: AAO41711.1
AL929472 Genomic DNA No translation available.
CH471059 Genomic DNA Translation: EAX07317.1
BC008984 mRNA Translation: AAH08984.3 Different initiation.
BC067857 mRNA Translation: AAH67857.2
BC068057 mRNA Translation: AAH68057.1
BC080186 mRNA Translation: AAH80186.2
AY286019 mRNA Translation: AAP37053.1 Different initiation.
AY286020 mRNA Translation: AAP37054.1 Different initiation.
AF250397 mRNA Translation: AAQ14263.1
AK027129 mRNA Translation: BAB15668.1 Different initiation.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS30675.1

NCBI Reference Sequences

More...RefSeqi		NP_078916.3, NM_024640.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000373044; ENSP00000362135; ENSG00000196449

Database of genes from NCBI RefSeq genomes

More...GeneIDi		79693

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:79693

UCSC genome browser

More...UCSCi		uc001cca.2, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY172561 mRNA Translation: AAO41711.1
AL929472 Genomic DNA No translation available.
CH471059 Genomic DNA Translation: EAX07317.1
BC008984 mRNA Translation: AAH08984.3 Different initiation.
BC067857 mRNA Translation: AAH67857.2
BC068057 mRNA Translation: AAH68057.1
BC080186 mRNA Translation: AAH80186.2
AY286019 mRNA Translation: AAP37053.1 Different initiation.
AY286020 mRNA Translation: AAP37054.1 Different initiation.
AF250397 mRNA Translation: AAQ14263.1
AK027129 mRNA Translation: BAB15668.1 Different initiation.
CCDSiCCDS30675.1
RefSeqiNP_078916.3, NM_024640.3

3D structure databases

SMRiQ86U90
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi122814, 12 interactors
IntActiQ86U90, 7 interactors
STRINGi9606.ENSP00000362135

PTM databases

GlyGeniQ86U90, 1 site, 1 O-linked glycan (1 site)
iPTMnetiQ86U90
PhosphoSitePlusiQ86U90

Genetic variation databases

BioMutaiYRDC
DMDMi74750410

Proteomic databases

EPDiQ86U90
jPOSTiQ86U90
MassIVEiQ86U90
MaxQBiQ86U90
PaxDbiQ86U90
PeptideAtlasiQ86U90
PRIDEiQ86U90
ProteomicsDBi69783

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		31792, 26 antibodies

Genome annotation databases

EnsembliENST00000373044; ENSP00000362135; ENSG00000196449
GeneIDi79693
KEGGihsa:79693
UCSCiuc001cca.2, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		79693
DisGeNETi79693

GeneCards: human genes, protein and diseases

More...GeneCardsi		YRDC
HGNCiHGNC:28905, YRDC
HPAiENSG00000196449, Low tissue specificity
MIMi612276, gene
neXtProtiNX_Q86U90
OpenTargetsiENSG00000196449
PharmGKBiPA142670553
VEuPathDBiHostDB:ENSG00000196449.3

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3051, Eukaryota
GeneTreeiENSGT00390000015364
HOGENOMiCLU_031397_5_0_1
InParanoidiQ86U90
OMAiWHEQPLA
OrthoDBi1027994at2759
PhylomeDBiQ86U90
TreeFamiTF314358

Enzyme and pathway databases

PathwayCommonsiQ86U90

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		79693, 658 hits in 872 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		YRDC, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		79693
PharosiQ86U90, Tdark

Protein Ontology

More...PROi		PR:Q86U90
RNActiQ86U90, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000196449, Expressed in bone marrow and 214 other tissues
GenevisibleiQ86U90, HS

Family and domain databases

InterProiView protein in InterPro
IPR017945, DHBP_synth_RibB-like_a/b_dom
IPR006070, YrdC-like_dom
PfamiView protein in Pfam
PF01300, Sua5_yciO_yrdC, 1 hit
SUPFAMiSSF55821, SSF55821, 1 hit
TIGRFAMsiTIGR00057, TIGR00057, 1 hit
PROSITEiView protein in PROSITE
PS51163, YRDC, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYRDC_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86U90
Secondary accession number(s): Q4W4X8
, Q6NVW3, Q7L4E4, Q7Z2I4, Q9H5F8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: June 1, 2003
Last modified: February 10, 2021
This is version 136 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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