RBM23

Functionⁱ

Probable RNA-binding protein. May be involved in pre-mRNA splicing process.

GO - Molecular functionⁱ

mRNA binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
RNA binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
U1 snRNP binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

3'-UTR-mediated mRNA destabilization
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
mRNA processing Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	RNA-binding

Molecular function

RNA-binding

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Probable RNA-binding protein 23 Alternative name(s): RNA-binding motif protein 23 RNA-binding region-containing protein 4 Splicing factor SF2
Gene namesⁱ	Name:RBM23 Synonyms:RNPC4 ORF Names:PP239
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 14

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000100461.17
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:20155 RBM23
neXtProtⁱ	NX_Q86U06

Keywords - Cellular componentⁱ

Nucleus

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	55147
Open Targets More...OpenTargetsⁱ	ENSG00000100461
PharmGKBⁱ	PA134974852

Polymorphism and mutation databases

BioMutaⁱ	RBM23
DMDMⁱ	34925229

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000081783	1 – 439	Probable RNA-binding protein 23Add BLAST		439

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Modified residueⁱ	128	PhosphoserineCombined sources		1
Modified residueⁱ	149	PhosphoserineCombined sources		1

Keywords - PTMⁱ

Phosphoprotein

Proteomic databases

EPDⁱ	Q86U06
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q86U06
PaxDbⁱ	Q86U06
PeptideAtlas More...PeptideAtlasⁱ	Q86U06
PRIDEⁱ	Q86U06
ProteomicsDBⁱ	69751 69752 [Q86U06-2] 69753 [Q86U06-3] 69754 [Q86U06-4] 69755 [Q86U06-5]

PTM databases

iPTMnetⁱ	Q86U06
PhosphoSitePlusⁱ	Q86U06
SwissPalmⁱ	Q86U06

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000100461 Expressed in 223 organ(s), highest expression level in kidney
CleanExⁱ	HS_RBM23
ExpressionAtlasⁱ	Q86U06 baseline and differential
Genevisibleⁱ	Q86U06 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA004144

HPAⁱ

HPA004144

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct
BHLHE40	O14503	3	EBI-10258579,EBI-711810
FAM9B	Q8IZU0	3	EBI-780319,EBI-10175124
MAGEA11	P43364-2	3	EBI-10258579,EBI-10178634
MAGED1	Q9Y5V3	3	EBI-780319,EBI-716006
PRMT5	O14744	3	EBI-780319,EBI-351098
SRPK2	P78362	2	EBI-780319,EBI-593303
TRIM27	P14373	3	EBI-780319,EBI-719493

Protein-protein interaction databases

BioGridⁱ	120450, 55 interactors
IntActⁱ	Q86U06, 18 interactors
Molecular INTeraction database More...MINTⁱ	Q86U06
STRINGⁱ	9606.ENSP00000352956

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Helixⁱ	162 – 165	Combined sources	4
Beta strandⁱ	167 – 172	Combined sources	6
Helixⁱ	179 – 186	Combined sources	8
Turnⁱ	187 – 189	Combined sources	3
Beta strandⁱ	192 – 197	Combined sources	6
Beta strandⁱ	203 – 205	Combined sources	3
Beta strandⁱ	210 – 215	Combined sources	6
Helixⁱ	217 – 219	Combined sources	3
Helixⁱ	220 – 226	Combined sources	7
Beta strandⁱ	229 – 231	Combined sources	3
Beta strandⁱ	234 – 240	Combined sources	7
Helixⁱ	241 – 248	Combined sources	8
Beta strandⁱ	265 – 269	Combined sources	5
Helixⁱ	276 – 283	Combined sources	8
Turnⁱ	284 – 286	Combined sources	3
Beta strandⁱ	289 – 295	Combined sources	7
Beta strandⁱ	298 – 300	Combined sources	3
Beta strandⁱ	305 – 312	Combined sources	8
Helixⁱ	314 – 324	Combined sources	11
Beta strandⁱ	329 – 332	Combined sources	4
Beta strandⁱ	335 – 340	Combined sources	6

Show more details

3D structure databases

ProteinModelPortalⁱ	Q86U06
SMRⁱ	Q86U06
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Miscellaneous databases

EvolutionaryTraceⁱ	Q86U06

EvolutionaryTraceⁱ

Q86U06

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	166 – 243	RRM 1PROSITE-ProRule annotationAdd BLAST		78
Domainⁱ	263 – 341	RRM 2PROSITE-ProRule annotationAdd BLAST		79

Compositional bias

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Compositional biasⁱ	63 – 127	Arg-richAdd BLAST		65
Compositional biasⁱ	371 – 424	Ala-richAdd BLAST		54

Sequence similaritiesⁱ

Belongs to the splicing factor SR family.Curated

Keywords - Domainⁱ

Repeat

Phylogenomic databases

eggNOGⁱ	KOG0147 Eukaryota ENOG410XP20 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00930000150902
HOVERGENⁱ	HBG057646
InParanoidⁱ	Q86U06
OMAⁱ	MRVGQVT
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0BQ9
PhylomeDBⁱ	Q86U06
TreeFamⁱ	TF320448

Family and domain databases

Gene3Dⁱ	3.30.70.330, 2 hits
InterProⁱ	View protein in InterPro IPR012677 Nucleotide-bd_a/b_plait_sf IPR035979 RBD_domain_sf IPR029123 RBM39_linker IPR006509 RBM39_SF IPR000504 RRM_dom
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF15519 RBM39linker, 1 hit PF00076 RRM_1, 2 hits
SMARTⁱ	View protein in SMART SM00360 RRM, 2 hits
SUPFAMⁱ	SSF54928 SSF54928, 2 hits
TIGRFAMsⁱ	TIGR01622 SF-CC1, 1 hit
PROSITEⁱ	View protein in PROSITE PS50102 RRM, 2 hits

Sequences (5+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 5 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 5 described isoforms and 16 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q86U06-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MASDDFDIVI EAMLEAPYKK EEDEQQRKEV KKDYPSNTTS STSNSGNETS 
        60         70         80         90        100
GSSTIGETSK KKRSRSHNKS RDRKRSRSRD RDRYRRRNSR SRSPGRQCRH 
       110        120        130        140        150
RSRSWDRRHG SESRSRDHRR EDRVHYRSPP LATGYRYGHS KSPHFREKSP 
       160        170        180        190        200
VREPVDNLSP EERDARTVFC MQLAARIRPR DLEDFFSAVG KVRDVRIISD 
       210        220        230        240        250
RNSRRSKGIA YVEFCEIQSV PLAIGLTGQR LLGVPIIVQA SQAEKNRLAA 
       260        270        280        290        300
MANNLQKGNG GPMRLYVGSL HFNITEDMLR GIFEPFGKID NIVLMKDSDT 
       310        320        330        340        350
GRSKGYGFIT FSDSECARRA LEQLNGFELA GRPMRVGHVT ERLDGGTDIT 
       360        370        380        390        400
FPDGDQELDL GSAGGRFQLM AKLAEGAGIQ LPSTAAAAAA AAAQAAALQL 
       410        420        430 
NGAVPLGALN PAALTALSPA LNLASQCFQL SSLFTPQTM

Length:439

Mass (Da):48,731

Last modified:June 1, 2003 - v1

Checksum:ⁱCFF3E56F7EA12D0B

GO

Isoform 2 (identifier: Q86U06-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
60-76: KKKRSRSHNKSRDRKRS → N

« Hide

        10         20         30         40         50
MASDDFDIVI EAMLEAPYKK EEDEQQRKEV KKDYPSNTTS STSNSGNETS 
        60         70         80         90        100
GSSTIGETSN RSRDRDRYRR RNSRSRSPGR QCRHRSRSWD RRHGSESRSR 
       110        120        130        140        150
DHRREDRVHY RSPPLATGYR YGHSKSPHFR EKSPVREPVD NLSPEERDAR 
       160        170        180        190        200
TVFCMQLAAR IRPRDLEDFF SAVGKVRDVR IISDRNSRRS KGIAYVEFCE 
       210        220        230        240        250
IQSVPLAIGL TGQRLLGVPI IVQASQAEKN RLAAMANNLQ KGNGGPMRLY 
       260        270        280        290        300
VGSLHFNITE DMLRGIFEPF GKIDNIVLMK DSDTGRSKGY GFITFSDSEC 
       310        320        330        340        350
ARRALEQLNG FELAGRPMRV GHVTERLDGG TDITFPDGDQ ELDLGSAGGR 
       360        370        380        390        400
FQLMAKLAEG AGIQLPSTAA AAAAAAAQAA ALQLNGAVPL GALNPAALTA 
       410        420 
LSPALNLASQ CFQLSSLFTP QTM

Show »

Length:423

Mass (Da):46,708

Checksum:ⁱ0DD858657398EC9C

GO

Isoform 3 (identifier: Q86U06-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
311-319: FSDSECARR → LHPPPLGTV
320-439: Missing.

« Hide

        10         20         30         40         50
MASDDFDIVI EAMLEAPYKK EEDEQQRKEV KKDYPSNTTS STSNSGNETS 
        60         70         80         90        100
GSSTIGETSK KKRSRSHNKS RDRKRSRSRD RDRYRRRNSR SRSPGRQCRH 
       110        120        130        140        150
RSRSWDRRHG SESRSRDHRR EDRVHYRSPP LATGYRYGHS KSPHFREKSP 
       160        170        180        190        200
VREPVDNLSP EERDARTVFC MQLAARIRPR DLEDFFSAVG KVRDVRIISD 
       210        220        230        240        250
RNSRRSKGIA YVEFCEIQSV PLAIGLTGQR LLGVPIIVQA SQAEKNRLAA 
       260        270        280        290        300
MANNLQKGNG GPMRLYVGSL HFNITEDMLR GIFEPFGKID NIVLMKDSDT 
       310 
GRSKGYGFIT LHPPPLGTV

Show »

Length:319

Mass (Da):36,535

Checksum:ⁱ3983D6B0494B7EC8

GO

Isoform 4 (identifier: Q86U06-4) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
60-76: KKKRSRSHNKSRDRKRS → N
135-152: Missing.

« Hide

        10         20         30         40         50
MASDDFDIVI EAMLEAPYKK EEDEQQRKEV KKDYPSNTTS STSNSGNETS 
        60         70         80         90        100
GSSTIGETSN RSRDRDRYRR RNSRSRSPGR QCRHRSRSWD RRHGSESRSR 
       110        120        130        140        150
DHRREDRVHY RSPPLATGEP VDNLSPEERD ARTVFCMQLA ARIRPRDLED 
       160        170        180        190        200
FFSAVGKVRD VRIISDRNSR RSKGIAYVEF CEIQSVPLAI GLTGQRLLGV 
       210        220        230        240        250
PIIVQASQAE KNRLAAMANN LQKGNGGPMR LYVGSLHFNI TEDMLRGIFE 
       260        270        280        290        300
PFGKIDNIVL MKDSDTGRSK GYGFITFSDS ECARRALEQL NGFELAGRPM 
       310        320        330        340        350
RVGHVTERLD GGTDITFPDG DQELDLGSAG GRFQLMAKLA EGAGIQLPST 
       360        370        380        390        400
AAAAAAAAAQ AAALQLNGAV PLGALNPAAL TALSPALNLA SQCFQLSSLF 

TPQTM

Show »

Length:405

Mass (Da):44,495

Checksum:ⁱ1344E0827F28B86D

GO

Isoform 5 (identifier: Q86U06-5) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-100: MASDDFDIVI...SRSPGRQCRH → MSNKGKKLKR...AEVQVGSVVT

« Hide

        10         20         30         40         50
MSNKGKKLKR IILAIPPAAP ATVAMRPVEA APSGRQARRR GVGAIIKAGI 
        60         70         80         90        100
ESAVVVEIGI GIDGEIVGAE VQVGSVVTRS RSWDRRHGSE SRSRDHRRED 
       110        120        130        140        150
RVHYRSPPLA TGYRYGHSKS PHFREKSPVR EPVDNLSPEE RDARTVFCMQ 
       160        170        180        190        200
LAARIRPRDL EDFFSAVGKV RDVRIISDRN SRRSKGIAYV EFCEIQSVPL 
       210        220        230        240        250
AIGLTGQRLL GVPIIVQASQ AEKNRLAAMA NNLQKGNGGP MRLYVGSLHF 
       260        270        280        290        300
NITEDMLRGI FEPFGKIDNI VLMKDSDTGR SKGYGFITFS DSECARRALE 
       310        320        330        340        350
QLNGFELAGR PMRVGHVTER LDGGTDITFP DGDQELDLGS AGGRFQLMAK 
       360        370        380        390        400
LAEGAGIQLP STAAAAAAAA AQAAALQLNG AVPLGALNPA ALTALSPALN 
       410 
LASQCFQLSS LFTPQTM

Show »

Length:417

Mass (Da):44,930

Checksum:ⁱ88EB17EF60E117CB

GO

Computationally mapped potential isoform sequencesⁱ

There are 16 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name	Protein names	Gene names	Length	Annotation

	G3XAP0	G3XAP0_HUMAN	Probable RNA-binding protein 23 Probable RNA-binding protein 23 (RNA binding motif protein 23, isoform CRA_f)	RBM23 hCG_41980	269	Annotation score:
	G3V5Z6	G3V5Z6_HUMAN	Probable RNA-binding protein 23 Probable RNA-binding protein 23	RBM23	189	Annotation score:
	H0YJJ3	H0YJJ3_HUMAN	Probable RNA-binding protein 23 Probable RNA-binding protein 23	RBM23	214	Annotation score:
	G3V546	G3V546_HUMAN	Probable RNA-binding protein 23 Probable RNA-binding protein 23	RBM23	114	Annotation score:
	G3V2B4	G3V2B4_HUMAN	Probable RNA-binding protein 23 Probable RNA-binding protein 23	RBM23	50	Annotation score:
	G3V3V3	G3V3V3_HUMAN	Probable RNA-binding protein 23 Probable RNA-binding protein 23	RBM23	75	Annotation score:
	G3V5Y2	G3V5Y2_HUMAN	Probable RNA-binding protein 23 Probable RNA-binding protein 23	RBM23	144	Annotation score:
	H0YJN4	H0YJN4_HUMAN	Probable RNA-binding protein 23 Probable RNA-binding protein 23	RBM23	82	Annotation score:
	G3V2B6	G3V2B6_HUMAN	Probable RNA-binding protein 23 Probable RNA-binding protein 23	RBM23	101	Annotation score:
	G3V5V1	G3V5V1_HUMAN	Probable RNA-binding protein 23 Probable RNA-binding protein 23	RBM23	57	Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	132	A → T in AAG24388 (PubMed:14702039).Curated		1
Sequence conflictⁱ	321 – 330	LEQLNGFELA → CGTVEWGLSLL in AAP97203 (Ref. 1) Curated		10

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_052221	184	D → N. Corresponds to variant dbSNP:rs34246954Ensembl.	1
Natural variantⁱVAR_016841	393	A → AA4 Publications	1
Natural variantⁱVAR_052222	428	F → L. Corresponds to variant dbSNP:rs1127066Ensembl.	1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Length
Alternative sequenceⁱVSP_008311	1 – 100	MASDD…RQCRH → MSNKGKKLKRIILAIPPAAP ATVAMRPVEAAPSGRQARRR GVGAIIKAGIESAVVVEIGI GIDGEIVGAEVQVGSVVT in isoform 5. 1 PublicationAdd BLAST	100
Alternative sequenceⁱVSP_008312	60 – 76	KKKRS…DRKRS → N in isoform 2 and isoform 4. 3 PublicationsAdd BLAST	17
Alternative sequenceⁱVSP_008313	135 – 152	Missing in isoform 4. 1 PublicationAdd BLAST	18
Alternative sequenceⁱVSP_008314	311 – 319	FSDSECARR → LHPPPLGTV in isoform 3. 1 Publication	9
Alternative sequenceⁱVSP_008315	320 – 439	Missing in isoform 3. 1 PublicationAdd BLAST	120

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF087905 mRNA Translation: AAP97203.1 AF275678 mRNA Translation: AAG24388.1 AK001344 mRNA Translation: BAA91638.1 AL834198 mRNA Translation: CAD38887.1 BX161440 mRNA Translation: CAD61910.1 AL132780 Genomic DNA No translation available. AL135998 Genomic DNA No translation available. CH471078 Genomic DNA Translation: EAW66223.1 CH471078 Genomic DNA Translation: EAW66229.1 BC002566 mRNA Translation: AAH02566.1 BC024208 mRNA Translation: AAH24208.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS41919.1 [Q86U06-4] CCDS41920.1 [Q86U06-2] CCDS41921.1 [Q86U06-1]
NCBI Reference Sequences More...RefSeqⁱ	NP_001070819.1, NM_001077351.1 [Q86U06-1] NP_001070820.1, NM_001077352.1 [Q86U06-4] NP_001294973.1, NM_001308044.1 NP_060577.3, NM_018107.4 [Q86U06-2] XP_016876896.1, XM_017021407.1 XP_016876902.1, XM_017021413.1
UniGeneⁱ	Hs.4997

Genome annotation databases

Ensemblⁱ	ENST00000346528; ENSP00000339220; ENSG00000100461 [Q86U06-4] ENST00000359890; ENSP00000352956; ENSG00000100461 [Q86U06-1] ENST00000399922; ENSP00000382806; ENSG00000100461 [Q86U06-2]
GeneIDⁱ	55147
KEGGⁱ	hsa:55147
UCSC genome browser More...UCSCⁱ	uc001whg.4 human [Q86U06-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q86U06	RNA binding motif protein 23 isoform 2 (Fragment)		HUMAN		439	UniRef100_Q86U06
Probable RNA-binding protein 23		HUMAN		189
Probable RNA-binding protein 23		HUMAN		269
Probable RNA-binding protein 23 (Fragment)		HUMAN		82
UPI0000EE4A20		HUMAN		483
Q86U06-2	RNA binding motif protein 23 isoform 1 (Fragment)		HUMAN		423	UniRef100_Q86U06-2
UPI0000EE4A1F		HUMAN		467
Q86U06-4	RNA binding motif protein 23 isoform 3 (Fragment)		HUMAN		405	UniRef100_Q86U06-4
UPI0000EE4A1E		HUMAN		449

Protein	Similar proteins		Species	Score	Length	Source
Q86U06	RNA binding motif protein 23 isoform 2 (Fragment)		HUMAN		439	UniRef90_Q86U06
RBM23 isoform 1		PANTR		442
Uncharacterized protein		PANPA		426
Uncharacterized protein		NOMLE		426
Uncharacterized protein		MACNE		423
+61
Q86U06-4	RNA binding motif protein 23 isoform 3 (Fragment)		HUMAN		405	UniRef90_Q86U06-4
RNA binding motif protein 23		PANTR		408
Uncharacterized protein		NOMLE		408
RBM23 isoform 4		PONAB		405
Uncharacterized protein		Cebus capucinus imitator		404
+8

Protein	Similar proteins		Species	Score	Length	Source
Q86U06	RNA-binding protein 39	)	HUMAN		530	UniRef50_Q14498
RNA-binding protein 39	)	MOUSE		530
RNA-binding protein 39		PONAB		524
RNA binding motif protein 39		MACMU		530
RNA binding motif protein 39 isoform a (Predicted)		CALJA		530
+657
Q86U06-3	RNA binding motif protein 23		SAIBB		373	UniRef50_Q86U06-3
cDNA FLJ43605 fis, clone SPLEN2006122, highly similar to Probable RNA-binding protein 23		HUMAN		319
Uncharacterized protein		AOTNA		374
UPI000328839F		DASNO		323
UPI00070479EC		CAMFR		324
+14
Q86U06-4	RNA binding motif protein 23 isoform 3 (Fragment)		HUMAN		405	UniRef50_Q86U06-4
RBM23 isoform 6		PANTR		408
Uncharacterized protein		NOMLE		408
RBM23 isoform 4		PONAB		405
Uncharacterized protein		Cebus capucinus imitator		404
+61
Q86U06-5	probable RNA-binding protein 23 isoform X1		ERIEU		447	UniRef50_Q86U06-5
Putative RNA-binding protein 23		MYOBR		420
RNA-binding protein 39-like protein (Fragment)		HORSE		374
probable RNA-binding protein 23 isoform X2		ALLSI		424
Uncharacterized protein		CALJA		450
+93

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF087905 mRNA Translation: AAP97203.1 AF275678 mRNA Translation: AAG24388.1 AK001344 mRNA Translation: BAA91638.1 AL834198 mRNA Translation: CAD38887.1 BX161440 mRNA Translation: CAD61910.1 AL132780 Genomic DNA No translation available. AL135998 Genomic DNA No translation available. CH471078 Genomic DNA Translation: EAW66223.1 CH471078 Genomic DNA Translation: EAW66229.1 BC002566 mRNA Translation: AAH02566.1 BC024208 mRNA Translation: AAH24208.1
CCDSⁱ	CCDS41919.1 [Q86U06-4] CCDS41920.1 [Q86U06-2] CCDS41921.1 [Q86U06-1]
RefSeqⁱ	NP_001070819.1, NM_001077351.1 [Q86U06-1] NP_001070820.1, NM_001077352.1 [Q86U06-4] NP_001294973.1, NM_001308044.1 NP_060577.3, NM_018107.4 [Q86U06-2] XP_016876896.1, XM_017021407.1 XP_016876902.1, XM_017021413.1
UniGeneⁱ	Hs.4997

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	2CQ4	NMR	-	A	148-248	[»]
	2DNZ	NMR	-	A	265-346	[»]
ProteinModelPortalⁱ	Q86U06
SMRⁱ	Q86U06
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	120450, 55 interactors
IntActⁱ	Q86U06, 18 interactors
MINTⁱ	Q86U06
STRINGⁱ	9606.ENSP00000352956

PTM databases

iPTMnetⁱ	Q86U06
PhosphoSitePlusⁱ	Q86U06
SwissPalmⁱ	Q86U06

Polymorphism and mutation databases

BioMutaⁱ	RBM23
DMDMⁱ	34925229

Proteomic databases

EPDⁱ	Q86U06
MaxQBⁱ	Q86U06
PaxDbⁱ	Q86U06
PeptideAtlasⁱ	Q86U06
PRIDEⁱ	Q86U06
ProteomicsDBⁱ	69751 69752 [Q86U06-2] 69753 [Q86U06-3] 69754 [Q86U06-4] 69755 [Q86U06-5]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	55147
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000346528; ENSP00000339220; ENSG00000100461 [Q86U06-4] ENST00000359890; ENSP00000352956; ENSG00000100461 [Q86U06-1] ENST00000399922; ENSP00000382806; ENSG00000100461 [Q86U06-2]
GeneIDⁱ	55147
KEGGⁱ	hsa:55147
UCSCⁱ	uc001whg.4 human [Q86U06-1]

Organism-specific databases

CTDⁱ	55147
DisGeNETⁱ	55147
EuPathDBⁱ	HostDB:ENSG00000100461.17
GeneCardsⁱ	RBM23
HGNCⁱ	HGNC:20155 RBM23
HPAⁱ	HPA004144
neXtProtⁱ	NX_Q86U06
OpenTargetsⁱ	ENSG00000100461
PharmGKBⁱ	PA134974852
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG0147 Eukaryota ENOG410XP20 LUCA
GeneTreeⁱ	ENSGT00930000150902
HOVERGENⁱ	HBG057646
InParanoidⁱ	Q86U06
OMAⁱ	MRVGQVT
OrthoDBⁱ	EOG091G0BQ9
PhylomeDBⁱ	Q86U06
TreeFamⁱ	TF320448

Miscellaneous databases

ChiTaRSⁱ	RBM23 human
EvolutionaryTraceⁱ	Q86U06
GeneWikiⁱ	RBM23
GenomeRNAiⁱ	55147
Protein Ontology More...PROⁱ	PR:Q86U06

Gene expression databases

Bgeeⁱ	ENSG00000100461 Expressed in 223 organ(s), highest expression level in kidney
CleanExⁱ	HS_RBM23
ExpressionAtlasⁱ	Q86U06 baseline and differential
Genevisibleⁱ	Q86U06 HS

Family and domain databases

Gene3Dⁱ	3.30.70.330, 2 hits
InterProⁱ	View protein in InterPro IPR012677 Nucleotide-bd_a/b_plait_sf IPR035979 RBD_domain_sf IPR029123 RBM39_linker IPR006509 RBM39_SF IPR000504 RRM_dom
Pfamⁱ	View protein in Pfam PF15519 RBM39linker, 1 hit PF00076 RRM_1, 2 hits
SMARTⁱ	View protein in SMART SM00360 RRM, 2 hits
SUPFAMⁱ	SSF54928 SSF54928, 2 hits
TIGRFAMsⁱ	TIGR01622 SF-CC1, 1 hit
PROSITEⁱ	View protein in PROSITE PS50102 RRM, 2 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	RBM23_HUMAN
Accessionⁱ	Q86U06Primary (citable) accession number: Q86U06 Secondary accession number(s): D3DS32 , Q8ND16, Q8TB88, Q8WY40, Q9BUJ1, Q9NVV7
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	September 19, 2003
	Last sequence update:	June 1, 2003
	Last modified:	November 7, 2018
	This is version 156 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
PDB cross-references
Index of Protein Data Bank (PDB) cross-references
Human chromosome 14
Human chromosome 14: entries, gene names and cross-references to MIM

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UniProtKB - Q86U06 (RBM23_HUMAN)

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Probable RNA-binding protein 23

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Functionⁱ

GO - Molecular functionⁱ

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Names & Taxonomyⁱ

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Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

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Keywords - PTMⁱ

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Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

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