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Entry version 107 (16 Oct 2019)
Sequence version 1 (01 Jun 2003)
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Protein

Armadillo-like helical domain-containing protein 4

Gene

ARMH4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Armadillo-like helical domain-containing protein 4Curated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ARMH4Imported
Synonyms:C14orf37Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:19846 ARMH4

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q86TY3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini28 – 714ExtracellularSequence analysisAdd BLAST687
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei715 – 735HelicalSequence analysisAdd BLAST21
Topological domaini736 – 774CytoplasmicSequence analysisAdd BLAST39

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
145407

Open Targets

More...
OpenTargetsi
ENSG00000139971

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134941886

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q86TY3

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
C14orf37

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74750397

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 27Sequence analysisAdd BLAST27
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000025215228 – 774Armadillo-like helical domain-containing protein 4Add BLAST747

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi57N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi189N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei769PhosphoserineCombined sources1
Modified residuei770PhosphoserineCombined sources1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q86TY3

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q86TY3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q86TY3

PeptideAtlas

More...
PeptideAtlasi
Q86TY3

PRoteomics IDEntifications database

More...
PRIDEi
Q86TY3

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
69744 [Q86TY3-1]
69745 [Q86TY3-2]
69746 [Q86TY3-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q86TY3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q86TY3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000139971 Expressed in 152 organ(s), highest expression level in kidney

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q86TY3 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q86TY3 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA001580
HPA001789

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
126910, 8 interactors

Protein interaction database and analysis system

More...
IntActi
Q86TY3, 6 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000267485

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q86TY3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi608 – 636Glu-richAdd BLAST29
Compositional biasi740 – 743Poly-Arg4

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IG9G Eukaryota
ENOG410YWKQ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000012816

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000013177

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q86TY3

Identification of Orthologs from Complete Genome Data

More...
OMAi
TQCLAFP

Database of Orthologous Groups

More...
OrthoDBi
315961at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q86TY3

TreeFam database of animal gene trees

More...
TreeFami
TF336099

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR031524 ARMH4

The PANTHER Classification System

More...
PANTHERi
PTHR21585 PTHR21585, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15767 DUF4696, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q86TY3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRGPIVLHIC LAFCSLLLFS VATQCLAFPK IERRREIAHV HAEKGQSDKM
60 70 80 90 100
NTDDLENSSV TSKQTPQLVV SEDPMMMSAV PSATSLNKAF SINKETQPGQ
110 120 130 140 150
AGLMQTERPG VSTPTESGVP SAEEVFGSSQ PERISPESGL AKAMLTIAIT
160 170 180 190 200
ATPSLTVDEK EELLTSTNFQ PIVEEITETT KGFLKYMDNQ SFATESQEGV
210 220 230 240 250
GLGHSPSSYV NTKEMLTTNP KTEKFEADTD HRTTSFPGAE STAGSEPGSL
260 270 280 290 300
TPDKEKPSQM TADNTQAAAT KQPLETSEYT LSVEPETDSL LGAPEVTVSV
310 320 330 340 350
STAVPAASAL SDEWDDTKLE SVSRIRTPKL GDNEETQVRT EMSQTAQVSH
360 370 380 390 400
EGMEGGQPWT EAAQVALGLP EGETHTGTAL LIAHGNERSP AFTDQSSFTP
410 420 430 440 450
TSLMEDMKVS IVNLLQSTGD FTESTKENDA LFFLETTVSV SVYESEADQL
460 470 480 490 500
LGNTMKDIIT QEMTTAVQEP DATLSMVTQE QVATLELIRD SGKTEEEKED
510 520 530 540 550
PSPVSDVPGV TQLSRRWEPL ATTISTTVVP LSFEVTPTVE EQMDTVTGPN
560 570 580 590 600
EEFTPVLGSP VTPPGIMVGE PSISPALPAL EASSERRTVV PSITRVNTAA
610 620 630 640 650
SYGLDQLESE EGQEDEDEED EEDEDEEEED EEEDEEDKDA DSLDEGLDGD
660 670 680 690 700
TELPGFTLPG ITSQEPGLEE GNMDLLEGAT YQVPDALEWE QQNQGLVRSW
710 720 730 740 750
MEKLKDKAGY MSGMLVPVGV GIAGALFILG ALYSIKVMNR RRRNGFKRHK
760 770
RKQREFNSMQ DRVMLLADSS EDEF
Length:774
Mass (Da):84,173
Last modified:June 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0A74F08DF9BF5791
GO
Isoform 2 (identifier: Q86TY3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     612-670: GQEDEDEEDE...ITSQEPGLEE → TGFHHVAQAR...LNPKHFATGV
     671-774: Missing.

Note: No experimental confirmation available.
Show »
Length:670
Mass (Da):72,067
Checksum:i6E34390F03EBEA4F
GO
Isoform 3 (identifier: Q86TY3-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-542: Missing.

Note: No experimental confirmation available.
Show »
Length:232
Mass (Da):25,704
Checksum:i224C8EBE8707FEC0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WT98A0A087WT98_HUMAN
Armadillo-like helical domain-conta...
ARMH4
97Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti753Missing in AAH62772 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02778296T → I. Corresponds to variant dbSNP:rs3829765Ensembl.1
Natural variantiVAR_027783391A → V. Corresponds to variant dbSNP:rs1018504Ensembl.1
Natural variantiVAR_027784528V → F. Corresponds to variant dbSNP:rs12886921Ensembl.1
Natural variantiVAR_027785613Q → E. Corresponds to variant dbSNP:rs2273442Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0208811 – 542Missing in isoform 3. 1 PublicationAdd BLAST542
Alternative sequenceiVSP_020882612 – 670GQEDE…PGLEE → TGFHHVAQARLKLLGLRSLP ASASQSVGITSVNSCTQPRK YLNSCLKWKLNPKHFATGV in isoform 2. 1 PublicationAdd BLAST59
Alternative sequenceiVSP_020883671 – 774Missing in isoform 2. 1 PublicationAdd BLAST104

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX161411 mRNA Translation: CAD61887.1
BX161448 mRNA Translation: CAD61913.1
AK292513 mRNA Translation: BAF85202.1
CH471061 Genomic DNA Translation: EAW80713.1
BC062772 mRNA Translation: AAH62772.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS32089.1 [Q86TY3-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001001872.2, NM_001001872.3 [Q86TY3-1]
NP_001307102.1, NM_001320173.1 [Q86TY3-2]
XP_016876518.1, XM_017021029.1 [Q86TY3-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000267485; ENSP00000267485; ENSG00000139971 [Q86TY3-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
145407

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:145407

UCSC genome browser

More...
UCSCi
uc001xdc.4 human [Q86TY3-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX161411 mRNA Translation: CAD61887.1
BX161448 mRNA Translation: CAD61913.1
AK292513 mRNA Translation: BAF85202.1
CH471061 Genomic DNA Translation: EAW80713.1
BC062772 mRNA Translation: AAH62772.1
CCDSiCCDS32089.1 [Q86TY3-1]
RefSeqiNP_001001872.2, NM_001001872.3 [Q86TY3-1]
NP_001307102.1, NM_001320173.1 [Q86TY3-2]
XP_016876518.1, XM_017021029.1 [Q86TY3-1]

3D structure databases

SMRiQ86TY3
ModBaseiSearch...

Protein-protein interaction databases

BioGridi126910, 8 interactors
IntActiQ86TY3, 6 interactors
STRINGi9606.ENSP00000267485

PTM databases

iPTMnetiQ86TY3
PhosphoSitePlusiQ86TY3

Polymorphism and mutation databases

BioMutaiC14orf37
DMDMi74750397

Proteomic databases

jPOSTiQ86TY3
MassIVEiQ86TY3
PaxDbiQ86TY3
PeptideAtlasiQ86TY3
PRIDEiQ86TY3
ProteomicsDBi69744 [Q86TY3-1]
69745 [Q86TY3-2]
69746 [Q86TY3-3]

Genome annotation databases

EnsembliENST00000267485; ENSP00000267485; ENSG00000139971 [Q86TY3-1]
GeneIDi145407
KEGGihsa:145407
UCSCiuc001xdc.4 human [Q86TY3-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
145407
DisGeNETi145407

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ARMH4
HGNCiHGNC:19846 ARMH4
HPAiHPA001580
HPA001789
neXtProtiNX_Q86TY3
OpenTargetsiENSG00000139971
PharmGKBiPA134941886

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IG9G Eukaryota
ENOG410YWKQ LUCA
GeneTreeiENSGT00390000012816
HOGENOMiHOG000013177
InParanoidiQ86TY3
OMAiTQCLAFP
OrthoDBi315961at2759
PhylomeDBiQ86TY3
TreeFamiTF336099

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
C14orf37 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
145407
PharosiQ86TY3

Protein Ontology

More...
PROi
PR:Q86TY3

Gene expression databases

BgeeiENSG00000139971 Expressed in 152 organ(s), highest expression level in kidney
ExpressionAtlasiQ86TY3 baseline and differential
GenevisibleiQ86TY3 HS

Family and domain databases

InterProiView protein in InterPro
IPR031524 ARMH4
PANTHERiPTHR21585 PTHR21585, 1 hit
PfamiView protein in Pfam
PF15767 DUF4696, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiARMD4_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86TY3
Secondary accession number(s): A8K8Z8, Q6P5Q1, Q86TY1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: June 1, 2003
Last modified: October 16, 2019
This is version 107 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  2. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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