UniProtKB - Q86TM6 (SYVN1_HUMAN)
E3 ubiquitin-protein ligase synoviolin
SYVN1
Functioni
Catalytic activityi
- S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.6 Publications EC:2.3.2.27
: protein ubiquitination Pathwayi
This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.6 PublicationsView all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 291 | Zinc 1Combined sources1 Publication | 1 | |
Metal bindingi | 294 | Zinc 1Combined sources1 Publication | 1 | |
Metal bindingi | 307 | Zinc 2Combined sources1 Publication | 1 | |
Metal bindingi | 309 | Zinc 2Combined sources1 Publication | 1 | |
Metal bindingi | 312 | Zinc 1Combined sources1 Publication | 1 | |
Metal bindingi | 315 | Zinc 1Combined sources1 Publication | 1 | |
Metal bindingi | 326 | Zinc 2Combined sources1 Publication | 1 | |
Metal bindingi | 329 | Zinc 2Combined sources1 Publication | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 291 – 330 | RING-type; atypicalPROSITE-ProRule annotationAdd BLAST | 40 |
GO - Molecular functioni
- ATPase binding Source: ParkinsonsUK-UCL
- chaperone binding Source: ParkinsonsUK-UCL
- metal ion binding Source: UniProtKB-KW
- ubiquitin protein ligase activity Source: ParkinsonsUK-UCL
- ubiquitin-specific protease binding Source: ParkinsonsUK-UCL
- unfolded protein binding Source: ParkinsonsUK-UCL
GO - Biological processi
- endoplasmic reticulum mannose trimming Source: Reactome
- ERAD pathway Source: ParkinsonsUK-UCL
- immature B cell differentiation Source: UniProtKB
- IRE1-mediated unfolded protein response Source: Reactome
- negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway Source: ParkinsonsUK-UCL
- protein K48-linked ubiquitination Source: ParkinsonsUK-UCL
- protein stabilization Source: ParkinsonsUK-UCL
- protein ubiquitination Source: ParkinsonsUK-UCL
- retrograde protein transport, ER to cytosol Source: ParkinsonsUK-UCL
- ubiquitin-dependent ERAD pathway Source: UniProtKB
- ubiquitin-dependent protein catabolic process Source: ParkinsonsUK-UCL
Keywordsi
Molecular function | Transferase |
Biological process | Stress response, Ubl conjugation pathway |
Ligand | Metal-binding, Zinc |
Enzyme and pathway databases
PathwayCommonsi | Q86TM6 |
Reactomei | R-HSA-381038, XBP1(S) activates chaperone genes R-HSA-5358346, Hedgehog ligand biogenesis R-HSA-5362768, Hh mutants that don't undergo autocatalytic processing are degraded by ERAD R-HSA-901032, ER Quality Control Compartment (ERQC) |
SIGNORi | Q86TM6 |
UniPathwayi | UPA00143 |
Protein family/group databases
TCDBi | 3.A.16.1.4, the endoplasmic reticular retrotranslocon (er-rt) family |
Names & Taxonomyi
Protein namesi | Recommended name: E3 ubiquitin-protein ligase synoviolin (EC:2.3.2.276 Publications)Alternative name(s): RING-type E3 ubiquitin transferase synoviolin1 Publication Synovial apoptosis inhibitor 1 |
Gene namesi | Name:SYVN1 Synonyms:HRD1, KIAA1810 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000162298.16 |
HGNCi | HGNC:20738, SYVN1 |
MIMi | 608046, gene |
neXtProti | NX_Q86TM6 |
Subcellular locationi
Endoplasmic reticulum
- Endoplasmic reticulum membrane 5 Publications; Multi-pass membrane protein 4 Publications
Endoplasmic reticulum
- Derlin-1 retrotranslocation complex Source: ParkinsonsUK-UCL
- endoplasmic reticulum Source: UniProtKB
- endoplasmic reticulum membrane Source: Reactome
- endoplasmic reticulum quality control compartment Source: ParkinsonsUK-UCL
- Hrd1p ubiquitin ligase complex Source: ParkinsonsUK-UCL
- Hrd1p ubiquitin ligase ERAD-L complex Source: UniProtKB
- integral component of endoplasmic reticulum membrane Source: ParkinsonsUK-UCL
- smooth endoplasmic reticulum Source: ParkinsonsUK-UCL
Nucleus
- nucleoplasm Source: HPA
Other locations
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 4 | CytoplasmicCurated | 4 | |
Transmembranei | 5 – 25 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 26 – 41 | LumenalCuratedAdd BLAST | 16 | |
Transmembranei | 42 – 62 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 63 – 98 | CytoplasmicCuratedAdd BLAST | 36 | |
Transmembranei | 99 – 119 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 120 – 140 | LumenalCuratedAdd BLAST | 21 | |
Transmembranei | 141 – 161 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 162 – 169 | CytoplasmicCurated | 8 | |
Transmembranei | 170 – 190 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 191 – 224 | LumenalCuratedAdd BLAST | 34 | |
Transmembranei | 225 – 245 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 246 – 617 | CytoplasmicCuratedAdd BLAST | 372 |
Keywords - Cellular componenti
Endoplasmic reticulum, MembranePathology & Biotechi
Involvement in diseasei
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 294 | C → A: No effect on interaction with FAM8A1, HERPUD1, OS9, SEL1L and UBE2J1. 1 Publication | 1 | |
Mutagenesisi | 329 | C → S: Abolishes E3 ligase activity. 1 Publication | 1 | |
Mutagenesisi | 503 | R → L: Loss of interaction with FAM8A1, HERPUD1, OS9 and UBE2J1, impaired degradation of immature core-glycosylated basigin/CD147. 1 Publication | 1 |
Organism-specific databases
DisGeNETi | 84447 |
OpenTargetsi | ENSG00000162298 |
PharmGKBi | PA128394735 |
Miscellaneous databases
Pharosi | Q86TM6, Tbio |
Polymorphism and mutation databases
BioMutai | SYVN1 |
DMDMi | 134035039 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000280548 | 1 – 617 | E3 ubiquitin-protein ligase synoviolinAdd BLAST | 617 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 613 | PhosphoserineCombined sources | 1 |
Post-translational modificationi
Keywords - PTMi
Phosphoprotein, Ubl conjugationProteomic databases
EPDi | Q86TM6 |
jPOSTi | Q86TM6 |
MassIVEi | Q86TM6 |
MaxQBi | Q86TM6 |
PaxDbi | Q86TM6 |
PeptideAtlasi | Q86TM6 |
PRIDEi | Q86TM6 |
ProteomicsDBi | 69713 [Q86TM6-1] 69714 [Q86TM6-2] 69715 [Q86TM6-3] |
PTM databases
iPTMneti | Q86TM6 |
PhosphoSitePlusi | Q86TM6 |
Expressioni
Tissue specificityi
Inductioni
Gene expression databases
Bgeei | ENSG00000162298, Expressed in right lobe of liver and 207 other tissues |
ExpressionAtlasi | Q86TM6, baseline and differential |
Genevisiblei | Q86TM6, HS |
Organism-specific databases
HPAi | ENSG00000162298, Low tissue specificity |
Interactioni
Subunit structurei
Homodimer (PubMed:16289116).
Interacts with p53/TP53 (PubMed:17170702).
Interacts with HTT (PubMed:17141218).
Component of the HRD1 complex, which comprises at least SYNV1/HRD1, DERL1/2, FAM8A1, HERPUD1/HERP, OS9, SEL1L and UBE2J1 (PubMed:16289116, PubMed:16186509, PubMed:18264092, PubMed:26471130, PubMed:28827405). FAM8A1 is stabilized by interaction with SYNV1, which prevents its proteasomal degradation. OS9 and UBE2J1 recruitment to the complex may be mediated by SEL1L (PubMed:28827405). SYNV1 assembles with SEL1L and FAM8A1 through its transmembrane domains, but interaction with its cytoplasmic domain is required to confer stability to FAM8A1 and enhance recruitment of HERPUD1 (PubMed:28827405). The HRD1 complex also associates with VIMP and may transfer misfolded proteins from the endoplasmic reticulum to VCP (PubMed:16289116). May form a complex with ERLEC1; HSPA5; OS9 AND SEL1L (PubMed:18502753, PubMed:18264092).
Interacts with VCP (PubMed:16289116, PubMed:16186510).
Interacts with UBXN6 (PubMed:18656546).
Interacts with BAG6 (PubMed:21636303).
Interacts with NFE2L1 (By similarity).
Interacts (via N-terminus) with components of the pre-B cell receptor, including IGLL1 and VPREB1 (By similarity).
Interacts with CREB3L3; this interaction leads to CREB3L3 ubiquitination and proteasomal degradation (By similarity).
By similarity11 PublicationsBinary interactionsi
Hide detailsQ86TM6
With | #Exp. | IntAct |
---|---|---|
ERN1 [O75460] | 2 | EBI-947849,EBI-371750 |
ERN1 - isoform 1 [O75460-1] | 3 | EBI-947849,EBI-15600828 |
TP53 [P04637] | 5 | EBI-947849,EBI-366083 |
GO - Molecular functioni
- ATPase binding Source: ParkinsonsUK-UCL
- chaperone binding Source: ParkinsonsUK-UCL
- ubiquitin-specific protease binding Source: ParkinsonsUK-UCL
- unfolded protein binding Source: ParkinsonsUK-UCL
Protein-protein interaction databases
BioGRIDi | 124085, 205 interactors |
CORUMi | Q86TM6 |
DIPi | DIP-43982N |
IntActi | Q86TM6, 29 interactors |
MINTi | Q86TM6 |
STRINGi | 9606.ENSP00000366395 |
Miscellaneous databases
RNActi | Q86TM6, protein |
Structurei
Secondary structure
3D structure databases
SMRi | Q86TM6 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 251 | Involved in FAM8A1 interaction1 PublicationAdd BLAST | 251 | |
Regioni | 1 – 84 | Necessary and sufficient for SEL1L interaction1 PublicationAdd BLAST | 84 | |
Regioni | 236 – 270 | Interaction with p53/TP531 PublicationAdd BLAST | 35 | |
Regioni | 480 – 535 | HAF-H domain; necessary to form higher-order Hrd1 complexes1 PublicationAdd BLAST | 56 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 339 – 478 | Pro-richAdd BLAST | 140 |
Domaini
Sequence similaritiesi
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 291 – 330 | RING-type; atypicalPROSITE-ProRule annotationAdd BLAST | 40 |
Keywords - Domaini
Transmembrane, Transmembrane helix, Zinc-fingerPhylogenomic databases
eggNOGi | KOG0802, Eukaryota |
GeneTreei | ENSGT00940000157743 |
HOGENOMi | CLU_009169_3_0_1 |
InParanoidi | Q86TM6 |
OMAi | MPGAYGM |
OrthoDBi | 897451at2759 |
PhylomeDBi | Q86TM6 |
TreeFami | TF318635 |
Family and domain databases
Gene3Di | 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR032832, E3_lig_synoviolin/Hrd1 IPR001841, Znf_RING IPR013083, Znf_RING/FYVE/PHD |
PANTHERi | PTHR22763:SF173, PTHR22763:SF173, 1 hit |
Pfami | View protein in Pfam PF13639, zf-RING_2, 1 hit |
SMARTi | View protein in SMART SM00184, RING, 1 hit |
PROSITEi | View protein in PROSITE PS50089, ZF_RING_2, 1 hit |
s (3+)i Sequence
Sequence statusi: Complete.
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 3 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MFRTAVMMAA SLALTGAVVA HAYYLKHQFY PTVVYLTKSS PSMAVLYIQA
60 70 80 90 100
FVLVFLLGKV MGKVFFGQLR AAEMEHLLER SWYAVTETCL AFTVFRDDFS
110 120 130 140 150
PRFVALFTLL LFLKCFHWLA EDRVDFMERS PNISWLFHCR IVSLMFLLGI
160 170 180 190 200
LDFLFVSHAY HSILTRGASV QLVFGFEYAI LMTMVLTIFI KYVLHSVDLQ
210 220 230 240 250
SENPWDNKAV YMLYTELFTG FIKVLLYMAF MTIMIKVHTF PLFAIRPMYL
260 270 280 290 300
AMRQFKKAVT DAIMSRRAIR NMNTLYPDAT PEELQAMDNV CIICREEMVT
310 320 330 340 350
GAKRLPCNHI FHTSCLRSWF QRQQTCPTCR MDVLRASLPA QSPPPPEPAD
360 370 380 390 400
QGPPPAPHPP PLLPQPPNFP QGLLPPFPPG MFPLWPPMGP FPPVPPPPSS
410 420 430 440 450
GEAVAPPSTS AAALSRPSGA ATTTAAGTSA TAASATASGP GSGSAPEAGP
460 470 480 490 500
APGFPFPPPW MGMPLPPPFA FPPMPVPPAG FAGLTPEELR ALEGHERQHL
510 520 530 540 550
EARLQSLRNI HTLLDAAMLQ INQYLTVLAS LGPPRPATSV NSTEETATTV
560 570 580 590 600
VAAASSTSIP SSEATTPTPG ASPPAPEMER PPAPESVGTE EMPEDGEPDA
610
AELRRRRLQK LESPVAH
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketE9PMA1 | E9PMA1_HUMAN | RING-type E3 ubiquitin transferase | SYVN1 | 236 | Annotation score: | ||
E9PK19 | E9PK19_HUMAN | RING-type E3 ubiquitin transferase | SYVN1 | 237 | Annotation score: | ||
H0YCR6 | H0YCR6_HUMAN | RING-type E3 ubiquitin transferase | SYVN1 | 149 | Annotation score: | ||
E9PN88 | E9PN88_HUMAN | RING-type E3 ubiquitin transferase | SYVN1 | 149 | Annotation score: |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 145 | M → I in BAC24801 (PubMed:12459480).Curated | 1 | |
Sequence conflicti | 145 | M → I in AAL26903 (PubMed:14593114).Curated | 1 | |
Sequence conflicti | 545 | E → G in BAC57449 (PubMed:12975321).Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_023777 | 127 – 177 | Missing in isoform 2. 1 PublicationAdd BLAST | 51 | |
Alternative sequenceiVSP_023778 | 411 | Missing in isoform 2 and isoform 3. 4 Publications | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB085847 mRNA Translation: BAC24801.1 AB024690 mRNA Translation: BAC57449.1 AF317634 mRNA Translation: AAL26903.1 AB058713 mRNA Translation: BAB47439.1 Different initiation. AL834262 mRNA Translation: CAD38937.1 BC030530 mRNA Translation: AAH30530.1 |
CCDSi | CCDS31605.1 [Q86TM6-1] CCDS8097.1 [Q86TM6-3] |
RefSeqi | NP_115807.1, NM_032431.2 [Q86TM6-3] NP_757385.1, NM_172230.2 [Q86TM6-1] XP_011543605.1, XM_011545303.2 [Q86TM6-1] |
Genome annotation databases
Ensembli | ENST00000294256; ENSP00000294256; ENSG00000162298 [Q86TM6-3] ENST00000307289; ENSP00000302035; ENSG00000162298 [Q86TM6-2] ENST00000377190; ENSP00000366395; ENSG00000162298 [Q86TM6-1] ENST00000526060; ENSP00000436984; ENSG00000162298 [Q86TM6-3] |
GeneIDi | 84447 |
KEGGi | hsa:84447 |
UCSCi | uc001odb.4, human [Q86TM6-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB085847 mRNA Translation: BAC24801.1 AB024690 mRNA Translation: BAC57449.1 AF317634 mRNA Translation: AAL26903.1 AB058713 mRNA Translation: BAB47439.1 Different initiation. AL834262 mRNA Translation: CAD38937.1 BC030530 mRNA Translation: AAH30530.1 |
CCDSi | CCDS31605.1 [Q86TM6-1] CCDS8097.1 [Q86TM6-3] |
RefSeqi | NP_115807.1, NM_032431.2 [Q86TM6-3] NP_757385.1, NM_172230.2 [Q86TM6-1] XP_011543605.1, XM_011545303.2 [Q86TM6-1] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
6A3Z | NMR | - | A | 279-334 | [»] | |
SMRi | Q86TM6 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 124085, 205 interactors |
CORUMi | Q86TM6 |
DIPi | DIP-43982N |
IntActi | Q86TM6, 29 interactors |
MINTi | Q86TM6 |
STRINGi | 9606.ENSP00000366395 |
Protein family/group databases
TCDBi | 3.A.16.1.4, the endoplasmic reticular retrotranslocon (er-rt) family |
PTM databases
iPTMneti | Q86TM6 |
PhosphoSitePlusi | Q86TM6 |
Polymorphism and mutation databases
BioMutai | SYVN1 |
DMDMi | 134035039 |
Proteomic databases
EPDi | Q86TM6 |
jPOSTi | Q86TM6 |
MassIVEi | Q86TM6 |
MaxQBi | Q86TM6 |
PaxDbi | Q86TM6 |
PeptideAtlasi | Q86TM6 |
PRIDEi | Q86TM6 |
ProteomicsDBi | 69713 [Q86TM6-1] 69714 [Q86TM6-2] 69715 [Q86TM6-3] |
Protocols and materials databases
Antibodypediai | 1694, 370 antibodies |
DNASUi | 84447 |
Genome annotation databases
Ensembli | ENST00000294256; ENSP00000294256; ENSG00000162298 [Q86TM6-3] ENST00000307289; ENSP00000302035; ENSG00000162298 [Q86TM6-2] ENST00000377190; ENSP00000366395; ENSG00000162298 [Q86TM6-1] ENST00000526060; ENSP00000436984; ENSG00000162298 [Q86TM6-3] |
GeneIDi | 84447 |
KEGGi | hsa:84447 |
UCSCi | uc001odb.4, human [Q86TM6-1] |
Organism-specific databases
CTDi | 84447 |
DisGeNETi | 84447 |
EuPathDBi | HostDB:ENSG00000162298.16 |
GeneCardsi | SYVN1 |
HGNCi | HGNC:20738, SYVN1 |
HPAi | ENSG00000162298, Low tissue specificity |
MIMi | 608046, gene |
neXtProti | NX_Q86TM6 |
OpenTargetsi | ENSG00000162298 |
PharmGKBi | PA128394735 |
HUGEi | Search... |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG0802, Eukaryota |
GeneTreei | ENSGT00940000157743 |
HOGENOMi | CLU_009169_3_0_1 |
InParanoidi | Q86TM6 |
OMAi | MPGAYGM |
OrthoDBi | 897451at2759 |
PhylomeDBi | Q86TM6 |
TreeFami | TF318635 |
Enzyme and pathway databases
UniPathwayi | UPA00143 |
PathwayCommonsi | Q86TM6 |
Reactomei | R-HSA-381038, XBP1(S) activates chaperone genes R-HSA-5358346, Hedgehog ligand biogenesis R-HSA-5362768, Hh mutants that don't undergo autocatalytic processing are degraded by ERAD R-HSA-901032, ER Quality Control Compartment (ERQC) |
SIGNORi | Q86TM6 |
Miscellaneous databases
BioGRID-ORCSi | 84447, 202 hits in 863 CRISPR screens |
ChiTaRSi | SYVN1, human |
GeneWikii | SYVN1 |
GenomeRNAii | 84447 |
Pharosi | Q86TM6, Tbio |
PROi | PR:Q86TM6 |
RNActi | Q86TM6, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000162298, Expressed in right lobe of liver and 207 other tissues |
ExpressionAtlasi | Q86TM6, baseline and differential |
Genevisiblei | Q86TM6, HS |
Family and domain databases
Gene3Di | 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR032832, E3_lig_synoviolin/Hrd1 IPR001841, Znf_RING IPR013083, Znf_RING/FYVE/PHD |
PANTHERi | PTHR22763:SF173, PTHR22763:SF173, 1 hit |
Pfami | View protein in Pfam PF13639, zf-RING_2, 1 hit |
SMARTi | View protein in SMART SM00184, RING, 1 hit |
PROSITEi | View protein in PROSITE PS50089, ZF_RING_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SYVN1_HUMAN | |
Accessioni | Q86TM6Primary (citable) accession number: Q86TM6 Secondary accession number(s): Q8N3K3 Q96PK3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 20, 2007 |
Last sequence update: | March 20, 2007 | |
Last modified: | December 2, 2020 | |
This is version 167 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PATHWAY comments
Index of metabolic and biosynthesis pathways - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families - Human chromosome 11
Human chromosome 11: entries, gene names and cross-references to MIM