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Protein
Submitted name:

Homeobox C4

Gene

HOXC4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi156 – 215HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental proteinSAAS annotation, DNA-bindingPROSITE-ProRule annotationSAAS annotationImported

Names & Taxonomyi

Protein namesi
Submitted name:
Homeobox C4Imported
Gene namesi
Name:HOXC4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA29401

PTM / Processingi

Proteomic databases

MaxQBiQ86TF7
PeptideAtlasiQ86TF7

Expressioni

Gene expression databases

GenevisibleiQ86TF7 HS

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
NCK2O436393EBI-10185009,EBI-713635

Protein-protein interaction databases

IntActiQ86TF7, 1 interactor

Structurei

3D structure databases

ProteinModelPortaliQ86TF7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini154 – 214HomeoboxInterPro annotationAdd BLAST61

Sequence similaritiesi

Belongs to the Antp homeobox family.UniRule annotationSAAS annotation

Keywords - Domaini

HomeoboxPROSITE-ProRule annotationSAAS annotationImported

Phylogenomic databases

eggNOGiKOG0489 Eukaryota
ENOG410ZTBY LUCA
HOVERGENiHBG016849
KOiK09304

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017995 Homeobox_antennapedia
IPR001827 Homeobox_Antennapedia_CS
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR020479 Homeobox_metazoa
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PRINTSiPR00025 ANTENNAPEDIA
PR00024 HOMEOBOX
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS00032 ANTENNAPEDIA, 1 hit
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q86TF7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIMSSYLMDS NYIDPKFPPC EEYSQNSYIP EHSPEYYGRT RESGFQHHHQ
60 70 80 90 100
ELYPPPPPRP SYPERQYSCT SLQGPGNSRG HGPAQAGHHH PEKSQSLCEP
110 120 130 140 150
APLSGASASP SPAPPACSQP APDHPSSAAS KQPIVYPWMK KIHVSTVNPS
160 170 180 190 200
YNGGEPKRSR TAYTRQQVLE LEKEFHYNRY LTRRRRIEIA HSLCLSERQI
210 220 230 240 250
KIWFQNRRMK WKKDHRLPNT KVRSAPPAGA APSTLSAATP GTSEDHSQSA
260
TPPEQQRAED ITRL
Length:264
Mass (Da):29,784
Last modified:June 1, 2003 - v1
Checksum:iB1CD1A0B08C2F903
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC050442 mRNA Translation: AAH50442.1
RefSeqiNP_055435.2, NM_014620.5
NP_705897.1, NM_153633.2
UniGeneiHs.549040

Genome annotation databases

GeneIDi3221
KEGGihsa:3221

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC050442 mRNA Translation: AAH50442.1
RefSeqiNP_055435.2, NM_014620.5
NP_705897.1, NM_153633.2
UniGeneiHs.549040

3D structure databases

ProteinModelPortaliQ86TF7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ86TF7, 1 interactor

Proteomic databases

MaxQBiQ86TF7
PeptideAtlasiQ86TF7

Protocols and materials databases

DNASUi3221
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3221
KEGGihsa:3221

Organism-specific databases

CTDi3221
PharmGKBiPA29401

Phylogenomic databases

eggNOGiKOG0489 Eukaryota
ENOG410ZTBY LUCA
HOVERGENiHBG016849
KOiK09304

Miscellaneous databases

ChiTaRSiHOXC4 human
GenomeRNAii3221

Gene expression databases

GenevisibleiQ86TF7 HS

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017995 Homeobox_antennapedia
IPR001827 Homeobox_Antennapedia_CS
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR020479 Homeobox_metazoa
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PRINTSiPR00025 ANTENNAPEDIA
PR00024 HOMEOBOX
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS00032 ANTENNAPEDIA, 1 hit
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ86TF7_HUMAN
AccessioniPrimary (citable) accession number: Q86TF7
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: September 12, 2018
This is version 137 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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