UniProtKB - Q86SR6 (Q86SR6_HUMAN)
Protein
Submitted name:
ELK1, member of ETS oncogene family
Gene
N/A
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity Source: InterPro
- sequence-specific DNA binding Source: InterPro
Keywordsi
Molecular function | DNA-bindingUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: ELK1, member of ETS oncogene familyImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Nucleus
- Nucleus UniRule annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusUniRule annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 31 – 112 | ETSInterPro annotationAdd BLAST | 82 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 147 – 175 | DisorderedSequence analysisAdd BLAST | 29 | |
Regioni | 191 – 231 | DisorderedSequence analysisAdd BLAST | 41 | |
Regioni | 321 – 382 | DisorderedSequence analysisAdd BLAST | 62 |
Sequence similaritiesi
Phylogenomic databases
OMAi | NTAQVCG |
OrthoDBi | 981551at2759 |
Family and domain databases
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR000418, Ets_dom IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF00178, Ets, 1 hit |
PRINTSi | PR00454, ETSDOMAIN |
SMARTi | View protein in SMART SM00413, ETS, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS00345, ETS_DOMAIN_1, 1 hit PS00346, ETS_DOMAIN_2, 1 hit PS50061, ETS_DOMAIN_3, 1 hit |
i Sequence
Sequence statusi: Fragment.
Q86SR6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
RSCQHCQRHR HATHRYPWDG VSTPPAMDPS VTLWQFLLQL LREQGNGHII
60 70 80 90 100
SWTSRDGGEF KLVDAEEVAR LWGLRKNKTN MNYDKLSRAL RYYYDKNIIR
110 120 130 140 150
KVSGQKFVYK FVSYPEVAGC STEDCPPQPE VSVTSTMPNV APAAIHAAPG
160 170 180 190 200
DTVSGKPGTP KGAGMAGPGG LARSSRNEYM RSGLYSTFTI QSLQPQPPPH
210 220 230 240 250
PRPAVVLPSA APAGAAAPPS GSRSTSPSPL EACLEAEEAG LPLQVILTPP
260 270 280 290 300
EAPNLKSEEL NVEPGLGRAL PPEVKVEGPK EELEVAGERG FVPETTKAEP
310 320 330 340 350
EVPPQEGVPA RLPAVVMDTA GQAGGHAASS PEISQPQKGR KPRDLELPLS
360 370 380 390 400
PSLLGGPGPE RTPGSGSGSG LQAPGPALTP SLLPTHTLTP VLLTPSSLPP
410 420 430 440 450
SIHFWSTLSP IAPRSPAKLS FQFPSSGSAQ VHIPSISVDG LSTPVVLSPG
PQKP
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC048296 mRNA Translation: AAH48296.1 |
RefSeqi | NP_005220.2, NM_005229.4 |
Genome annotation databases
GeneIDi | 2002 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC048296 mRNA Translation: AAH48296.1 |
RefSeqi | NP_005220.2, NM_005229.4 |
3D structure databases
SMRi | Q86SR6 |
ModBasei | Search... |
Protocols and materials databases
DNASUi | 2002 |
Genome annotation databases
GeneIDi | 2002 |
Organism-specific databases
CTDi | 2002 |
Phylogenomic databases
OMAi | NTAQVCG |
OrthoDBi | 981551at2759 |
Miscellaneous databases
BioGRID-ORCSi | 2002, 28 hits in 648 CRISPR screens |
GenomeRNAii | 2002 |
Family and domain databases
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR000418, Ets_dom IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF00178, Ets, 1 hit |
PRINTSi | PR00454, ETSDOMAIN |
SMARTi | View protein in SMART SM00413, ETS, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS00345, ETS_DOMAIN_1, 1 hit PS00346, ETS_DOMAIN_2, 1 hit PS50061, ETS_DOMAIN_3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q86SR6_HUMAN | |
Accessioni | Q86SR6Primary (citable) accession number: Q86SR6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 1, 2003 |
Last sequence update: | June 1, 2003 | |
Last modified: | April 7, 2021 | |
This is version 107 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |