Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Negative elongation factor A

Gene

Nelf-A

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. Has an essential role in postembryonic development.2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein, Repressor
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-112382 Formation of RNA Pol II elongation complex
R-DME-113418 Formation of the Early Elongation Complex
R-DME-674695 RNA Polymerase II Pre-transcription Events
R-DME-6796648 TP53 Regulates Transcription of DNA Repair Genes
R-DME-75955 RNA Polymerase II Transcription Elongation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Negative elongation factor A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Nelf-A
ORF Names:CG5874
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0038872 Nelf-A

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Loss of zygotic expression results in morphologically normal embryos that hatch as 1st instar larvae. These larvae survive for several days but do not increase in size. Loss of maternal expression causes arrest prior to the cellular blastoderm stage and embryos display abnormal nuclear morphology. Those that escape this early arrest proceed through the blastoderm stage and gastrulate normally, but then almost always arrest during germband retraction with head defects and incomplete dorsal closure.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002191281 – 1251Negative elongation factor AAdd BLAST1251

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q86NP2

PRoteomics IDEntifications database

More...
PRIDEi
Q86NP2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed both maternally and zygotically.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0038872 Expressed in 31 organ(s), highest expression level in embryo

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q86NP2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q86NP2 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the NELF complex.1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
67490, 6 interactors

Protein interaction database and analysis system

More...
IntActi
Q86NP2, 1 interactor

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0303402

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q86NP2

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini89 – 254HDAgPROSITE-ProRule annotationAdd BLAST166

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni128 – 191NELF-C/D-bindingPROSITE-ProRule annotationAdd BLAST64
Regioni192 – 254RNAPII-bindingPROSITE-ProRule annotationAdd BLAST63

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi294 – 320Ala-richAdd BLAST27
Compositional biasi497 – 542Thr-richAdd BLAST46
Compositional biasi583 – 1149Gln-richAdd BLAST567

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the NELF-A family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IGI5 Eukaryota
ENOG410XRP9 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000005342

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q86NP2

KEGG Orthology (KO)

More...
KOi
K15179

Database of Orthologous Groups

More...
OrthoDBi
EOG091G081C

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q86NP2

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037517 HDAG_dom
IPR026305 NELF-A

The PANTHER Classification System

More...
PANTHERi
PTHR13328 PTHR13328, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51838 HDAG, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q86NP2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MANVRDSDTS LWLHNKLGTS NDSWINGSIC SQLNKEVLRN IKECFPDLQT
60 70 80 90 100
QVKLKLLLSF LHIPRRLVEE WKAELEEVIE VAGLDSELWV SMLAETMKTF
110 120 130 140 150
PATSSLNTEI SDYEDTRPIF IDMVNDLRKL VTKHSDLGML PLECQYLNKN
160 170 180 190 200
ALISVVGQQP APVKHFTLKR KPKSAQLRTE LLHKSADAQS SLKKASAPTI
210 220 230 240 250
PLRSRGMPRK MTDTTPLKGI PSRMPTTGFR SATVPGNAAQ RPNLSRTPAG
260 270 280 290 300
RKDGGIKLIE FTEQPLGYAA AKKRKREQQL EEQQKKQEQK QQQAAAAAAA
310 320 330 340 350
AATAAASNAG DSSPTDAATA SGGETPVTPT SANNSFEIKM EPQQLNQSAG
360 370 380 390 400
SLEEPQDDEM SGKANMECDI ETPEYATATL DFAQATSTSV ADGQPGKPAV
410 420 430 440 450
ETKLKTPRTP KSAAKLNNNN NNNNNNSFNH TPKRIKQEIE IKSEEIIVPA
460 470 480 490 500
SIKLEKIETS PSTQRVSIQQ QPPSLVQRTP HLLIRSSPQK RQNNGATTSA
510 520 530 540 550
GTTTTTVGNT TIKMEKLDIK PMIRATGVSP STSAGTTTTL LTPQQLRQAA
560 570 580 590 600
NPLANLPNNI SVKITSAKAK AAAAAAATSS GSQTQSQQPQ TLQVQQAPQQ
610 620 630 640 650
SHPPLLINSS TPVILASSPS AQRAKALALP SSSTSATTTT TIPSQAIKTM
660 670 680 690 700
PLSQLKTATN SGPVIISQTI IQPAKRAQQQ AGTSSAAAAS QQQQQQQSQQ
710 720 730 740 750
QLLHQQIQQQ TQQQAQLPQQ PQQQQTQYIL ATPQQQPQQI QQQQQQQQPI
760 770 780 790 800
LPTLTSFSHS RPMPQTTTLY QATTPSGSGQ TPTKILLKTS GSSSVVMTPL
810 820 830 840 850
RQAQPQQATA VVSSNPPPLV ATSAAVVSPG QTTLNIQNVQ LPNRPVTIQP
860 870 880 890 900
ASQAAQQQHM QAQLQQQQPH PQHTIVANTT ATQQPKLSQV LMQPTAAVGT
910 920 930 940 950
SGVSALNVSP TSGKNKTIIL TQKGVILRNI GGDMYQQIPI SNVGNMQGLG
960 970 980 990 1000
GTTLMTTTAG PPSLVKTTPS SGVQLQQQQS GKQILPTLIP TSSLGGQHVI
1010 1020 1030 1040 1050
VQQQQPTNVI GNSQQQTIIR PVMTNVGGGL TTLPQGLTLI QRPGQQPQLV
1060 1070 1080 1090 1100
QVQAAPGSTQ RTIITQSNTA AAASQQQPRQ QQQQILVQHK PAPTLQQRLV
1110 1120 1130 1140 1150
TSTTSGGQGQ QGNPNAGLPR TVQVQVQAQQ QQQPQQQQAT QQQSQQAPQR
1160 1170 1180 1190 1200
RGLSLSNEHV HKAHEMFRKA NRVSRPDKAL ILGFMAGLRE NPRPNNENVL
1210 1220 1230 1240 1250
VIKLGETEEK VQQDNGHTAL CLVESHIRLD YNTGEWKTFQ NYRLQDQSAA

S
Length:1,251
Mass (Da):134,949
Last modified:May 30, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6A959443D06622D4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0B4LIF3A0A0B4LIF3_DROME
Negative elongation factor A, isofo...
Nelf-A BcDNA:SD07139, Dmel\CG5874, NELF, NELF-A, CG5874
1,250Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0B4KGH5A0A0B4KGH5_DROME
Negative elongation factor A, isofo...
Nelf-A BcDNA:SD07139, Dmel\CG5874, NELF, NELF-A, CG5874
1,264Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti390V → A in AAO42634 (PubMed:12537569).Curated1
Sequence conflicti422 – 424Missing in AAO42634 (PubMed:12537569).Curated3
Sequence conflicti467S → I in AAO42634 (PubMed:12537569).Curated1
Sequence conflicti534A → V in AAO42634 (PubMed:12537569).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF55869.3
BT004470 mRNA Translation: AAO42634.1

NCBI Reference Sequences

More...
RefSeqi
NP_650958.2, NM_142701.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Dm.11211

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0084051; FBpp0083453; FBgn0038872

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
42520

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG5874

UCSC genome browser

More...
UCSCi
CG5874-RA d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF55869.3
BT004470 mRNA Translation: AAO42634.1
RefSeqiNP_650958.2, NM_142701.2
UniGeneiDm.11211

3D structure databases

SMRiQ86NP2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi67490, 6 interactors
IntActiQ86NP2, 1 interactor
STRINGi7227.FBpp0303402

Proteomic databases

PaxDbiQ86NP2
PRIDEiQ86NP2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0084051; FBpp0083453; FBgn0038872
GeneIDi42520
KEGGidme:Dmel_CG5874
UCSCiCG5874-RA d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
42520
FlyBaseiFBgn0038872 Nelf-A

Phylogenomic databases

eggNOGiENOG410IGI5 Eukaryota
ENOG410XRP9 LUCA
GeneTreeiENSGT00390000005342
InParanoidiQ86NP2
KOiK15179
OrthoDBiEOG091G081C
PhylomeDBiQ86NP2

Enzyme and pathway databases

ReactomeiR-DME-112382 Formation of RNA Pol II elongation complex
R-DME-113418 Formation of the Early Elongation Complex
R-DME-674695 RNA Polymerase II Pre-transcription Events
R-DME-6796648 TP53 Regulates Transcription of DNA Repair Genes
R-DME-75955 RNA Polymerase II Transcription Elongation

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Nelf-A fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
42520

Protein Ontology

More...
PROi
PR:Q86NP2

Gene expression databases

BgeeiFBgn0038872 Expressed in 31 organ(s), highest expression level in embryo
ExpressionAtlasiQ86NP2 baseline and differential
GenevisibleiQ86NP2 DM

Family and domain databases

InterProiView protein in InterPro
IPR037517 HDAG_dom
IPR026305 NELF-A
PANTHERiPTHR13328 PTHR13328, 2 hits
PROSITEiView protein in PROSITE
PS51838 HDAG, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNELFA_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86NP2
Secondary accession number(s): Q9VDC7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 14, 2003
Last sequence update: May 30, 2006
Last modified: November 7, 2018
This is version 105 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again