Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 113 (07 Apr 2021)
Sequence version 1 (01 Jun 2003)
Previous versions | rss
Add a publicationFeedback
Protein

Hybrid signal transduction histidine kinase K

Gene

dhkK

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in a signal transduction pathway that regulates morphogenesis and controls entry into the culmination stage. May act via the regA pathway, being activated by a morphogenesis-stimulated ligand, reducing phosphodiesterase regA levels and allowing cAMP level to rise to promote the culmination stage. This protein probably undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. EC:2.7.13.3

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Receptor, Transducer, Transferase
Biological processTwo-component regulatory system
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Hybrid signal transduction histidine kinase K (EC:2.7.13.3)
Alternative name(s):
Protein sombrero
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:dhkK
Synonyms:smbA
ORF Names:DDB_G0277887
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDictyostelium discoideum (Slime mold)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri44689 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAmoebozoaEvoseaEumycetozoaDictyosteliaDictyostelialesDictyosteliaceaeDictyostelium
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002195 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Chromosome 3, Unassembled WGS sequence

Organism-specific databases

Dictyostelium discoideum online informatics resource

More...
dictyBasei
DDB_G0277887, dhkK

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei600 – 618HelicalSequence analysisAdd BLAST19
Transmembranei628 – 648HelicalSequence analysisAdd BLAST21
Transmembranei652 – 672HelicalSequence analysisAdd BLAST21
Transmembranei676 – 696HelicalSequence analysisAdd BLAST21
Transmembranei729 – 749HelicalSequence analysisAdd BLAST21
Transmembranei768 – 788HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003282721 – 1213Hybrid signal transduction histidine kinase KAdd BLAST1213

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei825Phosphohistidine; by autocatalysisPROSITE-ProRule annotation1
Modified residuei11254-aspartylphosphatePROSITE-ProRule annotation1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Activation probably requires transfer of a phosphate group between a histidine in the kinase core (transmitter) domain and an aspartate of the receiver domain.By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q86CZ2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

First expressed prior to the start of aggregation, becoming concentrated in the slug anterior. Later is expressed in the maturing spore head of the fruiting body.2 Publications

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
44689.DDB0214934

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q86CZ2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini822 – 1052Histidine kinasePROSITE-ProRule annotationAdd BLAST231
Domaini1076 – 1199Response regulatoryPROSITE-ProRule annotationAdd BLAST124

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi25 – 34Poly-Asn10
Compositional biasi95 – 100Poly-Asn6
Compositional biasi102 – 106Poly-Ser5
Compositional biasi117 – 142Poly-AsnAdd BLAST26
Compositional biasi155 – 159Poly-Gln5
Compositional biasi171 – 189Poly-SerAdd BLAST19
Compositional biasi303 – 311Poly-Asn9
Compositional biasi314 – 321Poly-Asn8
Compositional biasi322 – 329Poly-Ser8
Compositional biasi337 – 365Poly-AsnAdd BLAST29
Compositional biasi369 – 372Poly-Asn4
Compositional biasi460 – 469Poly-Gln10
Compositional biasi498 – 511Poly-GlnAdd BLAST14
Compositional biasi522 – 541Poly-GlnAdd BLAST20
Compositional biasi544 – 567Poly-AsnAdd BLAST24

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0519, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_269528_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q86CZ2

Identification of Orthologs from Complete Genome Data

More...
OMAi
CSKTIRE

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00082, HisKA, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.565.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011006, CheY-like_superfamily
IPR003594, HATPase_C
IPR036890, HATPase_C_sf
IPR005467, His_kinase_dom
IPR003661, HisK_dim/P
IPR036097, HisK_dim/P_sf
IPR004358, Sig_transdc_His_kin-like_C
IPR001789, Sig_transdc_resp-reg_receiver

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02518, HATPase_c, 1 hit
PF00512, HisKA, 1 hit
PF00072, Response_reg, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00344, BCTRLSENSOR

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00387, HATPase_c, 1 hit
SM00388, HisKA, 1 hit
SM00448, REC, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47384, SSF47384, 1 hit
SSF52172, SSF52172, 1 hit
SSF55874, SSF55874, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50109, HIS_KIN, 1 hit
PS50110, RESPONSE_REGULATORY, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q86CZ2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIELNNHSKI NKNENNTNTR NNSSNNNNNN NNINKTNTNK YFEYNQNSII
60 70 80 90 100
YSSIPNSFLS HHPNSVGSQC LSLNSFLPPK PPILLSIFNS DTIGNNNNNN
110 120 130 140 150
YSSSSSRNNS SGCSSSNNNN NNNNNNNNNN NNNNNNNNNN CNIEQYKNNQ
160 170 180 190 200
KQPKQQQQQK DQTIATQHRI SLSSSSSSSS LSSSSSSSSV KQSFQIVKRL
210 220 230 240 250
FGSLSEYMFP QKDEILYETD PYYLYQDDTQ SNDSNEFYDD TDIGSDIDEA
260 270 280 290 300
NLNNTYNIQN CNKTLYNKQQ QQAHFVNMNK NVNSNNGTGN SNQSNNVNKN
310 320 330 340 350
QQNNNNNNNN NSHNNNNGNQ NSSSSSSNSG ASGSGGNGNN NNNNNNNNNN
360 370 380 390 400
NNNNNNNSNS NSNNNSKSNN NNKKEGKDGA TMNGSHPLIP FRKKPAQVPS
410 420 430 440 450
PCFRMNSPNS DNDQYLDQLA LENSSKKSLV VYNTDNLDQW KHSHLNENFD
460 470 480 490 500
ILQNDLIDIQ QQQQQQQQQD NTLQYSSPIN KRQEQEQQHI PFQFTTEQQQ
510 520 530 540 550
QLQQQQQQQQ QNKTKQHPIL LQRQQQQKQK QQQQQQIQQE QIGNNNSNNN
560 570 580 590 600
NNINNNNNIN NNYNNVNDLM NKFEIDQKQH DSQQNLVEEK RTPSFHEHNI
610 620 630 640 650
IFNSFNFICS IVLDGSNIKS TEKYKAKLII GFCFTILSFI PSWIIFFWLS
660 670 680 690 700
GINKPAVMAI IAMPMSISSL VILKRTGSIH YPCHILCFTL CFALTINSYY
710 720 730 740 750
TGGHQSTIRL LMSTVPIISA LVLGRKASIQ WSLMVLSIYL LFFVANLYGH
760 770 780 790 800
EYVQGIPSII IRSHMNFIID VTIIIMTLIF TLCYQYFIDE AHRETKLKNA
810 820 830 840 850
QLTIAKDAAI EAYQARQEFL ATMSHEIRTP LNGLIGMATL LRDSHNLPPE
860 870 880 890 900
EKTMAKAVKS CGDILLRLVN DILDLSKLEA NQMGLEHIPF RMRELTQQIC
910 920 930 940 950
HVLSGQANEK NIHLSCEVSD KIPSILLGDS GRILQILMNL TGNALKFTQS
960 970 980 990 1000
GYVKIIIDLI EEESELVSLK KGEYNISFRV KDTGIGVPVE SHQKIFEAFV
1010 1020 1030 1040 1050
QADPSDSRKY GGSGLGLYLC AKLVRLMKGE IGVYNNPDCD GSTFWFILPL
1060 1070 1080 1090 1100
EEGTDQSMQQ MNNGARHKAF PQDCVKVLIA EDNIINQRVA VKFLEKIGIK
1110 1120 1130 1140 1150
AEVAGNGNEV LEILERQHYD LIFMDFQMPI LDGLRCSKTI REFEQNHKWN
1160 1170 1180 1190 1200
RICPSIFICG LTANTMSTDK KRCFDHGMNH FISKPFQLEQ LRSAIEMAIE
1210
HKQRNLMNLN IRN
Length:1,213
Mass (Da):137,716
Last modified:June 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i69B171E952D02195
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti253N → T in AAK54095 (Ref. 1) Curated1
Sequence conflicti431V → A in AAK54095 (Ref. 1) Curated1
Sequence conflicti443S → F in AAK54095 (Ref. 1) Curated1
Sequence conflicti457I → F in AAK54095 (Ref. 1) Curated1
Sequence conflicti509 – 510QQ → HL in AAK54095 (Ref. 1) Curated2
Sequence conflicti649L → V in AAK54095 (Ref. 1) Curated1
Sequence conflicti714T → P in AAK54095 (Ref. 1) Curated1
Sequence conflicti717I → P in AAK54095 (Ref. 1) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF362376 Genomic DNA Translation: AAK54095.1
AY263399 Genomic DNA Translation: AAP20874.1
AAFI02000023 Genomic DNA Translation: EAL68116.1

NCBI Reference Sequences

More...
RefSeqi
XP_642392.1, XM_637300.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
EAL68116; EAL68116; DDB_G0277887

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
8621597

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ddi:DDB_G0277887

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF362376 Genomic DNA Translation: AAK54095.1
AY263399 Genomic DNA Translation: AAP20874.1
AAFI02000023 Genomic DNA Translation: EAL68116.1
RefSeqiXP_642392.1, XM_637300.1

3D structure databases

SMRiQ86CZ2
ModBaseiSearch...

Protein-protein interaction databases

STRINGi44689.DDB0214934

Proteomic databases

PaxDbiQ86CZ2

Genome annotation databases

EnsemblProtistsiEAL68116; EAL68116; DDB_G0277887
GeneIDi8621597
KEGGiddi:DDB_G0277887

Organism-specific databases

dictyBaseiDDB_G0277887, dhkK

Phylogenomic databases

eggNOGiKOG0519, Eukaryota
HOGENOMiCLU_269528_0_0_1
InParanoidiQ86CZ2
OMAiCSKTIRE

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q86CZ2

Family and domain databases

CDDicd00082, HisKA, 1 hit
Gene3Di3.30.565.10, 1 hit
InterProiView protein in InterPro
IPR011006, CheY-like_superfamily
IPR003594, HATPase_C
IPR036890, HATPase_C_sf
IPR005467, His_kinase_dom
IPR003661, HisK_dim/P
IPR036097, HisK_dim/P_sf
IPR004358, Sig_transdc_His_kin-like_C
IPR001789, Sig_transdc_resp-reg_receiver
PfamiView protein in Pfam
PF02518, HATPase_c, 1 hit
PF00512, HisKA, 1 hit
PF00072, Response_reg, 1 hit
PRINTSiPR00344, BCTRLSENSOR
SMARTiView protein in SMART
SM00387, HATPase_c, 1 hit
SM00388, HisKA, 1 hit
SM00448, REC, 1 hit
SUPFAMiSSF47384, SSF47384, 1 hit
SSF52172, SSF52172, 1 hit
SSF55874, SSF55874, 1 hit
PROSITEiView protein in PROSITE
PS50109, HIS_KIN, 1 hit
PS50110, RESPONSE_REGULATORY, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDHKK_DICDI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86CZ2
Secondary accession number(s): Q54Y10, Q95PH2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: June 1, 2003
Last modified: April 7, 2021
This is version 113 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again