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Entry version 168 (19 Jan 2022)
Sequence version 1 (01 Jun 2003)
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Protein
Submitted name:

Chromator, isoform A

Gene

Chro

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Chromator, isoform AImported
Submitted name:
Chromator, isoform BImported
Submitted name:
Chromator, isoform CImported
Submitted name:
Chromator, isoform DImported
Submitted name:
Chromator, isoform EImported
Submitted name:
MIP27283p1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ChroImported
Synonyms:anon-EST:fe2E3Imported, ChizImported, ChrImported, CHRIZImported, ChrizImported, CHROImported, chroImported, Chro(Chriz)Imported, Chro-RBImported, Dmel\CG10712Imported, MRG15Imported
ORF Names:CG10712Imported, Dmel_CG10712Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3L

Organism-specific databases

Drosophila genome database

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FlyBasei
FBgn0044324, Chro

Eukaryotic Pathogen, Vector and Host Database Resources

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VEuPathDBi
VectorBase:FBgn0044324

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0044324, Expressed in embryo and 41 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

Protein interaction database and analysis system

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IntActi
Q86BS3, 15 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0078219

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini221 – 282ChromoInterPro annotationAdd BLAST62

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni139 – 221DisorderedSequence analysisAdd BLAST83
Regioni291 – 390DisorderedSequence analysisAdd BLAST100
Regioni534 – 591DisorderedSequence analysisAdd BLAST58
Regioni651 – 680DisorderedSequence analysisAdd BLAST30

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili711 – 743Sequence analysisAdd BLAST33

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi139 – 176Polar residuesSequence analysisAdd BLAST38
Compositional biasi185 – 200Polar residuesSequence analysisAdd BLAST16
Compositional biasi291 – 331Polar residuesSequence analysisAdd BLAST41
Compositional biasi340 – 386Polar residuesSequence analysisAdd BLAST47

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QSUN, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_005056_0_0_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
REPWIVA

Database of Orthologous Groups

More...
OrthoDBi
1075003at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016197, Chromo-like_dom_sf
IPR000953, Chromo/chromo_shadow_dom
IPR023780, Chromo_domain

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00385, Chromo, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00298, CHROMO, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54160, SSF54160, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50013, CHROMO_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q86BS3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLAQEISPTE IGKHANIIRA AQEELANMDV LVCGRCLRAY NFVEEFQAHK
60 70 80 90 100
EDACEKENAN LKESLDPKPT IWAFTLWKAT QLHSRKDASG SSWALYQHWV
110 120 130 140 150
KLDDSVREPW IVAGKTIQSF GKIAHGQLQD MPVRITKTVV NPNNNNTSNS
160 170 180 190 200
NNNNTSVSPT RKSPTGKLPT LANQLKDTEN ERPKSKPSTP TPSSVPSAGA
210 220 230 240 250
VKPNNRIAIR IDSKTDQRTE EPVEKIVAKR FNPRRKTHEY LVKWVDRSHH
260 270 280 290 300
ENTWEVMANL ERVPYFLQMF EKQLARQKLT REKGLDALKR MQSSGTNAKS
310 320 330 340 350
DTAAPHSPLP ASSQVSPSSR PSRTSKTKAM DAFKQWVNET VAGDGSSSPS
360 370 380 390 400
SANEDESSTE QEWPPSSGAI KRKLNNTDSS LEGSGLNDSM DLEDLEEDLP
410 420 430 440 450
SHTVKRLKNG GSSVQLNKPR IQSTEKQQTK INGNSTVVSP LTEQKMGEII
460 470 480 490 500
YTEDSTSSGM FRKPEMPNTI NLKKEKPECP VRYLSRSEVG SSTRGVFRVE
510 520 530 540 550
NSEAPAPVSP APVPQKVIAA PPAAGIAKRL PMARPAHSGA NSPITVGQRQ
560 570 580 590 600
HALRTPGHGP VTAALHRRPG VGGASHVRQN LQQAPGRAHP GGRVLARAGV
610 620 630 640 650
GTPQHRQQVQ TPQGAKAVTP EQKILQLSKS GDLKVTRKVV TREELLAQRS
660 670 680 690 700
AQARQRQALS QQQSSQQQKA TPARQRIVSK STIQPTPLQM ELEEEIHQHQ
710 720 730 740 750
AQLCPITGKL IGQEETQLQM EQEQQQEQQR EQLEAAAQAL LGSDQQVLTN
760 770 780 790 800
EDGSALLVRG EDGTVYQVAG KNAEGQTILV TQGPDGEQQF AYVAAAEGED
810 820 830 840 850
QDVLSLDHAV AEAVQAGEQV ESHGVGAATA DGEQILVSMT EEELAQHQVL
860 870 880 890 900
QQAEASAAGT GTPPTAQIHI TTSDSDGTES QIPAEVVQAD LPSPGGTRRV
910 920
VLLLQDGTFM MTEMHEDQFK TLNIPT
Length:926
Mass (Da):101,053
Last modified:June 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBB77A2712E035E11
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AAF51877.2
AE014296 Genomic DNA Translation: AAF51878.2
AE014296 Genomic DNA Translation: AAN12209.2
BT128821 mRNA Translation: AEM76810.1
AE014296 Genomic DNA Translation: AGB94919.1
AE014296 Genomic DNA Translation: AHN58175.1

NCBI Reference Sequences

More...
RefSeqi
NP_001262226.1, NM_001275297.1
NP_001287150.1, NM_001300221.1
NP_649426.3, NM_141169.3
NP_730762.2, NM_168975.2
NP_730763.2, NM_168976.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0078568; FBpp0078219; FBgn0044324
FBtr0078569; FBpp0078220; FBgn0044324
FBtr0078570; FBpp0078221; FBgn0044324
FBtr0332053; FBpp0304363; FBgn0044324
FBtr0346095; FBpp0311928; FBgn0044324

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
40508

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG10712

UCSC genome browser

More...
UCSCi
CG10712-RA, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AAF51877.2
AE014296 Genomic DNA Translation: AAF51878.2
AE014296 Genomic DNA Translation: AAN12209.2
BT128821 mRNA Translation: AEM76810.1
AE014296 Genomic DNA Translation: AGB94919.1
AE014296 Genomic DNA Translation: AHN58175.1
RefSeqiNP_001262226.1, NM_001275297.1
NP_001287150.1, NM_001300221.1
NP_649426.3, NM_141169.3
NP_730762.2, NM_168975.2
NP_730763.2, NM_168976.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiQ86BS3, 15 interactors
STRINGi7227.FBpp0078219

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
40508

Genome annotation databases

EnsemblMetazoaiFBtr0078568; FBpp0078219; FBgn0044324
FBtr0078569; FBpp0078220; FBgn0044324
FBtr0078570; FBpp0078221; FBgn0044324
FBtr0332053; FBpp0304363; FBgn0044324
FBtr0346095; FBpp0311928; FBgn0044324
GeneIDi40508
KEGGidme:Dmel_CG10712
UCSCiCG10712-RA, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
40508
FlyBaseiFBgn0044324, Chro
VEuPathDBiVectorBase:FBgn0044324

Phylogenomic databases

eggNOGiENOG502QSUN, Eukaryota
HOGENOMiCLU_005056_0_0_1
OMAiREPWIVA
OrthoDBi1075003at2759

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
40508, 0 hits in 1 CRISPR screen

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
40508

Gene expression databases

BgeeiFBgn0044324, Expressed in embryo and 41 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR016197, Chromo-like_dom_sf
IPR000953, Chromo/chromo_shadow_dom
IPR023780, Chromo_domain
PfamiView protein in Pfam
PF00385, Chromo, 1 hit
SMARTiView protein in SMART
SM00298, CHROMO, 1 hit
SUPFAMiSSF54160, SSF54160, 1 hit
PROSITEiView protein in PROSITE
PS50013, CHROMO_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ86BS3_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86BS3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: January 19, 2022
This is version 168 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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