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Protein

Probable splicing factor 3A subunit 1

Gene

sf3a1

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processmRNA processing, mRNA splicing

Names & Taxonomyi

Protein namesi
Recommended name:
Probable splicing factor 3A subunit 1
Gene namesi
Name:sf3a1
ORF Names:DDB_G0272676
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 2, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0272676 sf3a1

Subcellular locationi

GO - Cellular componenti

  • catalytic step 2 spliceosome Source: GO_Central
  • spliceosomal complex Source: dictyBase
  • U2 snRNP Source: GO_Central
  • U2-type prespliceosome Source: GO_Central
  • U2-type spliceosomal complex Source: UniProtKB

Keywords - Cellular componenti

Nucleus, Spliceosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003279061 – 760Probable splicing factor 3A subunit 1Add BLAST760

Proteomic databases

PaxDbiQ86A14
PRIDEiQ86A14

Interactioni

Subunit structurei

Component of splicing factor SF3A which is composed of three subunits.By similarity

Protein-protein interaction databases

STRINGi44689.DDB0233180

Structurei

3D structure databases

ProteinModelPortaliQ86A14
SMRiQ86A14
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati16 – 58SURP motif 1Add BLAST43
Repeati183 – 225SURP motif 2Add BLAST43
Domaini680 – 757Ubiquitin-likePROSITE-ProRule annotationAdd BLAST78

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili259 – 290Sequence analysisAdd BLAST32

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi71 – 80Poly-Ala10
Compositional biasi84 – 128Thr-richAdd BLAST45
Compositional biasi129 – 140Poly-GlnAdd BLAST12
Compositional biasi143 – 165Pro-richAdd BLAST23
Compositional biasi364 – 367Poly-Asn4
Compositional biasi449 – 452Poly-Gly4
Compositional biasi455 – 459Poly-Asn5
Compositional biasi550 – 557Poly-Gln8
Compositional biasi558 – 638Pro-richAdd BLAST81
Compositional biasi643 – 649Poly-Ser7

Sequence similaritiesi

Belongs to the SF3A1 family.Curated

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

eggNOGiKOG0007 Eukaryota
ENOG410XPNW LUCA
InParanoidiQ86A14
KOiK12825
OMAiVQTIEFT
PhylomeDBiQ86A14

Family and domain databases

Gene3Di1.10.10.790, 2 hits
InterProiView protein in InterPro
IPR022030 SF3A1
IPR000061 Surp
IPR035967 SWAP/Surp_sf
IPR029071 Ubiquitin-like_domsf
IPR000626 Ubiquitin_dom
PfamiView protein in Pfam
PF12230 PRP21_like_P, 1 hit
PF01805 Surp, 2 hits
PF00240 ubiquitin, 1 hit
SMARTiView protein in SMART
SM00648 SWAP, 2 hits
SM00213 UBQ, 1 hit
SUPFAMiSSF109905 SSF109905, 2 hits
SSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50128 SURP, 2 hits
PS50053 UBIQUITIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q86A14-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MANEIITPTE GELKTIIDKT AAYAAKLGES FENKVKQREG HNAKFNFMKE
60 70 80 90 100
GDQYYPYYRN KIVENKAKIQ ADAAAAAAAA NPKTPSTTTT TTTTTTATTP
110 120 130 140 150
LPTATATTTS PTPTTSSTIV PVPQTNSTQQ LQQQQQQQQQ TTPVFEKPQP
160 170 180 190 200
PPPPPPKKEP TQPDPLLYIL DVPDFMTPLE LDTIRLTAQF IAKNGDSFFM
210 220 230 240 250
ELASREVKNS QFDFLKPTNH LYEWFRALVE SYAQIIYPPQ GIKEQLKSNY
260 270 280 290 300
FSNKQTILER AMNRCEYNQL KEIEEQKKEE REDEEKTIIA SIDWHDFVIV
310 320 330 340 350
DTIEFNEDDL DDLPQPRTFD QLIAGDTPFG GSDFDNDGHG SNGKGGQDME
360 370 380 390 400
MEMDMEMEMD DEDNNNNEDE IEESSLSSTN TTGNLPPKDQ SKLKIVKDYQ
410 420 430 440 450
KSNSSVKSNA PTKLTQLCQF CKQEIPLDEM QEHMRIELIQ KQQRDSRLGG
460 470 480 490 500
GGSSNNNNNL TNTLTQDDDI ARNLQSFASK RVDIFGETES SKKQDEQPTQ
510 520 530 540 550
APKVIWDGHS GSIPRVQAAQ QAAQLAAQQA AQQKAAAIAA QQASQQQASQ
560 570 580 590 600
QQQQQLQPPQ PIGIHHHPQR HLPPGMMPPG MMPPGMMPPG MMPPGMVPPP
610 620 630 640 650
PFGMIPPGMV PPPPPGLMIP TAPPGLMIPP TQQQQLPPQT NTSPSSSSSI
660 670 680 690 700
KVEEPQSKKL KIDDVLIPES VWLQNNPNPV NLTVEMADKS NIYQITLQPT
710 720 730 740 750
DSISLLKEKI KELNGMPTNK QKLQAPGLSI LKDTCSIAFY NLKSLAIVTC
760
GQKKKGGKKK
Length:760
Mass (Da):84,276
Last modified:June 1, 2003 - v1
Checksum:i03C5ED04C5D17137
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000008 Genomic DNA Translation: EAS66956.1
RefSeqiXP_001134622.1, XM_001134622.1

Genome annotation databases

EnsemblProtistsiEAS66956; EAS66956; DDB_G0272676
GeneIDi8618597
KEGGiddi:DDB_G0272676

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000008 Genomic DNA Translation: EAS66956.1
RefSeqiXP_001134622.1, XM_001134622.1

3D structure databases

ProteinModelPortaliQ86A14
SMRiQ86A14
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi44689.DDB0233180

Proteomic databases

PaxDbiQ86A14
PRIDEiQ86A14

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEAS66956; EAS66956; DDB_G0272676
GeneIDi8618597
KEGGiddi:DDB_G0272676

Organism-specific databases

dictyBaseiDDB_G0272676 sf3a1

Phylogenomic databases

eggNOGiKOG0007 Eukaryota
ENOG410XPNW LUCA
InParanoidiQ86A14
KOiK12825
OMAiVQTIEFT
PhylomeDBiQ86A14

Miscellaneous databases

PROiPR:Q86A14

Family and domain databases

Gene3Di1.10.10.790, 2 hits
InterProiView protein in InterPro
IPR022030 SF3A1
IPR000061 Surp
IPR035967 SWAP/Surp_sf
IPR029071 Ubiquitin-like_domsf
IPR000626 Ubiquitin_dom
PfamiView protein in Pfam
PF12230 PRP21_like_P, 1 hit
PF01805 Surp, 2 hits
PF00240 ubiquitin, 1 hit
SMARTiView protein in SMART
SM00648 SWAP, 2 hits
SM00213 UBQ, 1 hit
SUPFAMiSSF109905 SSF109905, 2 hits
SSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50128 SURP, 2 hits
PS50053 UBIQUITIN_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSF3A1_DICDI
AccessioniPrimary (citable) accession number: Q86A14
Secondary accession number(s): Q1ZXM9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: June 1, 2003
Last modified: November 7, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
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Main funding by: National Institutes of Health

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