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UniProtKB - Q869W7 (S35B4_DICDI)
Protein
UDP-N-acetylglucosamine transporter slc35b4
Gene
slc35b4
Organism
Dictyostelium discoideum (Slime mold)
Status
Functioni
Sugar transporter that specifically mediates the transport of UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi.
By similarityGO - Molecular functioni
- transmembrane transporter activity Source: GO_Central
- UDP-N-acetylglucosamine transmembrane transporter activity Source: GO_Central
GO - Biological processi
- carbohydrate transport Source: UniProtKB-KW
Keywordsi
Biological process | Sugar transport, Transport |
Enzyme and pathway databases
Reactomei | R-DDI-727802, Transport of nucleotide sugars |
Protein family/group databases
TCDBi | 2.A.7.10.3, the drug/metabolite transporter (dmt) superfamily |
Names & Taxonomyi
Protein namesi | Recommended name: UDP-N-acetylglucosamine transporter slc35b4Alternative name(s): Solute carrier family 35 member B4 |
Gene namesi | Name:slc35b4 ORF Names:DDB_G0275061 |
Organismi | Dictyostelium discoideum (Slime mold) |
Taxonomic identifieri | 44689 [NCBI] |
Taxonomic lineagei | Eukaryota › Amoebozoa › Evosea › Eumycetozoa › Dictyostelia › Dictyosteliales › Dictyosteliaceae › Dictyostelium |
Proteomesi |
|
Organism-specific databases
dictyBasei | DDB_G0275061, slc35b4 |
Subcellular locationi
Golgi apparatus
- Golgi apparatus membrane By similarity; Multi-pass membrane protein By similarity
Endoplasmic reticulum
- integral component of endoplasmic reticulum membrane Source: GO_Central
Golgi apparatus
- integral component of Golgi membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 6 – 26 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 37 – 57 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 77 – 97 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 104 – 124 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 136 – 156 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 173 – 193 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 209 – 229 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 252 – 274 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 282 – 302 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 306 – 326 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Golgi apparatus, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000330913 | 1 – 351 | UDP-N-acetylglucosamine transporter slc35b4Add BLAST | 351 |
Proteomic databases
PaxDbi | Q869W7 |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1583, Eukaryota |
InParanoidi | Q869W7 |
PhylomeDBi | Q869W7 |
Family and domain databases
InterProi | View protein in InterPro IPR013657, UAA |
PANTHERi | PTHR10778, PTHR10778, 1 hit |
Pfami | View protein in Pfam PF08449, UAA, 1 hit |
i Sequence
Sequence statusi: Complete.
Q869W7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIFDSLISLI PISMIMVGCC SNVISLELIM KQSQSHAILV TFFQFATVAF
60 70 80 90 100
ISFFVNIRWK QVFSIFWIPI GLRERKIPLK TYFLMVSIFF ILSVLNNKAL
110 120 130 140 150
DCDIPIPFHM IFRSSSLLST IVIGSIFYRK SYSKQQILSL IMVTLGIIFA
160 170 180 190 200
TFSSMPDSKK EISLGHEPNL LRFSIGMLML IAAMFLSSIL GLIQEHTYKL
210 220 230 240 250
YGKDRHYETI FYSHLFSLPF FLLFKDDILH HIQLNNDSAL MALPFGFGSF
260 270 280 290 300
PTLWVYLIVN VLTQYVCIQG VFILTGKTST LTCTLVISIR KFLSIIISVI
310 320 330 340 350
YFNNHFTSLL FTGTILVFLG TFMYSTSGKV IEKPLPPTKQ VKEIEKEKKL
N
Sequence cautioni
The sequence EAL69811 differs from that shown. Reason: Erroneous gene model prediction.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAFI02000013 Genomic DNA Translation: EAL69811.1 Sequence problems. |
RefSeqi | XP_643778.1, XM_638686.1 |
Genome annotation databases
EnsemblProtistsi | EAL69811; EAL69811; DDB_G0275061 |
GeneIDi | 8619823 |
KEGGi | ddi:DDB_G0275061 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAFI02000013 Genomic DNA Translation: EAL69811.1 Sequence problems. |
RefSeqi | XP_643778.1, XM_638686.1 |
3D structure databases
SMRi | Q869W7 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 44689.DDB0167452 |
Protein family/group databases
TCDBi | 2.A.7.10.3, the drug/metabolite transporter (dmt) superfamily |
Proteomic databases
PaxDbi | Q869W7 |
Genome annotation databases
EnsemblProtistsi | EAL69811; EAL69811; DDB_G0275061 |
GeneIDi | 8619823 |
KEGGi | ddi:DDB_G0275061 |
Organism-specific databases
dictyBasei | DDB_G0275061, slc35b4 |
Phylogenomic databases
eggNOGi | KOG1583, Eukaryota |
InParanoidi | Q869W7 |
PhylomeDBi | Q869W7 |
Enzyme and pathway databases
Reactomei | R-DDI-727802, Transport of nucleotide sugars |
Miscellaneous databases
PROi | PR:Q869W7 |
Family and domain databases
InterProi | View protein in InterPro IPR013657, UAA |
PANTHERi | PTHR10778, PTHR10778, 1 hit |
Pfami | View protein in Pfam PF08449, UAA, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | S35B4_DICDI | |
Accessioni | Q869W7Primary (citable) accession number: Q869W7 Secondary accession number(s): Q554D3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 29, 2008 |
Last sequence update: | February 9, 2010 | |
Last modified: | February 23, 2022 | |
This is version 94 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Dictyostelium discoideum
Dictyostelium discoideum: entries, gene names and cross-references to dictyBase - SIMILARITY comments
Index of protein domains and families