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Entry version 96 (29 Sep 2021)
Sequence version 2 (10 Feb 2009)
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Protein

Midasin

Gene

mdn1

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits. Functions at successive maturation steps to remove ribosomal factors at critical transition points, first driving the exit of early pre-60S particles from the nucleolus and then driving late pre-60S particles from the nucleus.

By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi302 – 309ATPSequence analysis8
Nucleotide bindingi689 – 696ATPSequence analysis8
Nucleotide bindingi1135 – 1142ATPSequence analysis8
Nucleotide bindingi1438 – 1445ATPSequence analysis8
Nucleotide bindingi1852 – 1859ATPSequence analysis8
Nucleotide bindingi2184 – 2191ATPSequence analysis8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Midasin
Alternative name(s):
Dynein-related AAA-ATPase mdn1
MIDAS-containing protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mdn1
ORF Names:DDB_G0295765
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDictyostelium discoideum (Slime mold)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri44689 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAmoebozoaEvoseaEumycetozoaDictyosteliaDictyostelialesDictyosteliaceaeDictyostelium
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002195 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Chromosome 2, Unassembled WGS sequence

Organism-specific databases

Dictyostelium discoideum online informatics resource

More...
dictyBasei
DDB_G0295765, mdn1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003633851 – 5900MidasinAdd BLAST5900

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q869L3

PRoteomics IDEntifications database

More...
PRIDEi
Q869L3

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Associates with pre-60S ribosomes in the nucleoplasm.

By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
44689.DDB0252730

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini5696 – 5889VWFAPROSITE-ProRule annotationAdd BLAST194

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni250 – 270DisorderedSequence analysisAdd BLAST21
Regioni278 – 583AAA-ATPase protomer 1Sequence analysisAdd BLAST306
Regioni673 – 1012AAA-ATPase protomer 2Sequence analysisAdd BLAST340
Regioni796 – 826DisorderedSequence analysisAdd BLAST31
Regioni1101 – 1346AAA-ATPase protomer 3Sequence analysisAdd BLAST246
Regioni1411 – 1721AAA-ATPase protomer 4Sequence analysisAdd BLAST311
Regioni1840 – 2089AAA-ATPase protomer 5Sequence analysisAdd BLAST250
Regioni2167 – 2451AAA-ATPase protomer 6Sequence analysisAdd BLAST285
Regioni2562 – 4965LinkerBy similarityAdd BLAST2404
Regioni4932 – 5598DisorderedSequence analysisAdd BLAST667

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi796 – 824Polar residuesSequence analysisAdd BLAST29
Compositional biasi4932 – 4985Basic and acidic residuesSequence analysisAdd BLAST54
Compositional biasi4986 – 5006Acidic residuesSequence analysisAdd BLAST21
Compositional biasi5007 – 5054Basic and acidic residuesSequence analysisAdd BLAST48
Compositional biasi5055 – 5073Acidic residuesSequence analysisAdd BLAST19
Compositional biasi5074 – 5116Basic and acidic residuesSequence analysisAdd BLAST43
Compositional biasi5117 – 5132Acidic residuesSequence analysisAdd BLAST16
Compositional biasi5142 – 5158Acidic residuesSequence analysisAdd BLAST17
Compositional biasi5159 – 5176Basic and acidic residuesSequence analysisAdd BLAST18
Compositional biasi5177 – 5213Acidic residuesSequence analysisAdd BLAST37
Compositional biasi5214 – 5228Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi5229 – 5257Acidic residuesSequence analysisAdd BLAST29
Compositional biasi5335 – 5374Polar residuesSequence analysisAdd BLAST40
Compositional biasi5386 – 5401Basic and acidic residuesSequence analysisAdd BLAST16
Compositional biasi5410 – 5449Basic and acidic residuesSequence analysisAdd BLAST40
Compositional biasi5450 – 5466Polar residuesSequence analysisAdd BLAST17
Compositional biasi5472 – 5488Acidic residuesSequence analysisAdd BLAST17
Compositional biasi5489 – 5551Basic and acidic residuesSequence analysisAdd BLAST63
Compositional biasi5573 – 5588Acidic residuesSequence analysisAdd BLAST16

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the midasin family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1808, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000050_0_2_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q869L3

Identification of Orthologs from Complete Genome Data

More...
OMAi
ELGPPNI

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q869L3

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.300, 5 hits
3.40.50.410, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593, AAA+_ATPase
IPR040848, AAA_lid_7
IPR011704, ATPase_dyneun-rel_AAA
IPR012099, Midasin
IPR041190, Midasin_AAA_lid_5
IPR027417, P-loop_NTPase
IPR025662, Sigma_54_int_dom_ATP-bd_1
IPR002035, VWF_A
IPR036465, vWFA_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07728, AAA_5, 8 hits
PF17865, AAA_lid_5, 1 hit
PF17867, AAA_lid_7, 3 hits

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF010340, Midasin, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382, AAA, 5 hits
SM00327, VWA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 6 hits
SSF53300, SSF53300, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00675, SIGMA54_INTERACT_1, 1 hit
PS50234, VWFA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q869L3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYKFKFNIFK AIKALELELT KIKNESSSST IIQDFKSFEQ IFKKKENEFT
60 70 80 90 100
SQDKLFIVEE ISNLLMSKPE YPSLISNIFS PLLVDLVSRY IQNGKKEERW
110 120 130 140 150
LGLVQSCFRL LSFNKSLFSS LWDWTPLFSL LEIKSQRITW YVIKSMSMVL
160 170 180 190 200
NVPDHQITQI KPLFKQYHNQ IIQIESELLN LESSKLFLNN NNNNNNKKEN
210 220 230 240 250
INNNQEEEKE DEELINKYPN IFIQKQDLHK SIVDVCGILL FKKFEQIGHG
260 270 280 290 300
SSVKSKKGGE QQQEGEGEDE QVQKLVYTNT VSQNLNSLAI AVGLGKPILI
310 320 330 340 350
EGVTGSGKTT MIEELSRITG NDNIIRIHLG DQTDSKVLLG TYITSDTPGE
360 370 380 390 400
FKWQAGALTQ AVQEGRWILI EDIDLAPIEV LSVLIPLLEN RTLFIPGRGE
410 420 430 440 450
VIEASNGFQL FATQTLFGSH SRDQNANILS HLWTRVVIEA LSPTEMKQVL
460 470 480 490 500
LTLFPQLTVM ISKFIETFNL LLRVISNQSI SISPTDEVAG IANIANTANV
510 520 530 540 550
NNINNNNNTD NNNNNNSNEK FIIPSSRFIS SRDLIKWIRR CNQRLHLTNV
560 570 580 590 600
SQQIITSTMQ EIVFVEALDC FCSMISKKNL RKQLTQVIGR VWELTGDRIN
610 620 630 640 650
YYVELYKPSI IITQESVSTG RAKLKSLEKS DSIQISNGKK HTRFTTEQSQ
660 670 680 690 700
QDSGVTKHGN VFAHTMNSLR LMEKISISIQ FNEPILLVGE TGTGKTSVVQ
710 720 730 740 750
YIADQLNQKL VVLNLNQQSD SSDLIGGFKP VEMRLLCLPL KNRFDSMFKK
760 770 780 790 800
TFSESNNTDF LEKIDKAFIS KNWKQFIALL NKAIKLVENK VLKDDQTTTN
810 820 830 840 850
NTKENNNNNN NNNNNNNNNN NNKKRTIRSE VKEKWIKLSN DIKKLTIQFE
860 870 880 890 900
KSKNNFAFSF VEGSLVNCIR KGYWVLLDEM NLATSETLES LSGLFDGGSI
910 920 930 940 950
TLTEKGEVEP VERHPNFKVF ACMNPPTDIG KKDLPPGIRN RFTEYYVDDL
960 970 980 990 1000
DNRGDLCLVV KTVLSNLVPN PPIEDIVEFY LKTKQDAQNK MLDGSNQKPI
1010 1020 1030 1040 1050
FSLRTLSRAL NYTKHVTKSF GFQRALFEGI SMSFLTQLNK SSYPMMEQLI
1060 1070 1080 1090 1100
KQYIKKGEVK LYNQPLNRPP PTSTTNNNNN NAEESYVKIE QFWIECGNEK
1110 1120 1130 1140 1150
PIIPTHYILT PSIKSNLSNI ARVLVSRKHP ILLQGPTSSG KTSMVEYLAI
1160 1170 1180 1190 1200
RTGHRFIRIN NHEHTDLQEY LGQYISDDKG KLVFQEGILV EAVRKGYWVV
1210 1220 1230 1240 1250
LDELNLAPSE VLEALNRLLD DNRELFIPET QEVVRPHPHF MLFATQNPPG
1260 1270 1280 1290 1300
LYGGRKVLSR AFRNRFLELH VDDIPEDELE EILCKRCALP PSYCKKLVLI
1310 1320 1330 1340 1350
MKELQLNRQG SNQVFAGKHG AITFRDLFRW AERQPSSYEE LGIAGYQLLA
1360 1370 1380 1390 1400
ERLRKDEEKL IIKQVIEKHL KIKLDIESIY SCDDKPEFLK LLQLLSENDS
1410 1420 1430 1440 1450
ELSKSNHLEK IVWTRSMKRL FSLVGKCLEH KEPILLVGET GCSKTTICQL
1460 1470 1480 1490 1500
YSILNKQKLH ILNCHQHTET ADFIGGLRPV RGRDQVLSKL YSLVKQYFNQ
1510 1520 1530 1540 1550
LSQLNLYKLE QENNNIDELP IKEIMERLIV ESWKQVSNSS LLTEQLKQLA
1560 1570 1580 1590 1600
IEIDKTYSSY CSLFNWVDGP LVEAMKQGDY FLIDEISLAE DAVLERLNSV
1610 1620 1630 1640 1650
LEPSRLLVLA EKGGVEIEEL RGHKEFRILA TMNPGGDFGK KELSPAMRNR
1660 1670 1680 1690 1700
FTEIWVPAIS SHQDLLQIIE ERFTSPQLKG KGSLMLNFIE YLLMIQKNKR
1710 1720 1730 1740 1750
VISLRDILSW ISFMNLCMDK QLLSPNESYI HGACLVLLDG FGMGSNSSSE
1760 1770 1780 1790 1800
SEGLKLREAC LIRLIDQIES QDEKLKLQTE LLSTSSSSSS LSSSIANIIK
1810 1820 1830 1840 1850
EENRFGIHPF YIPVRESNVP KIQFSLSAPT TSKNAQRVLR GMQLPRAILV
1860 1870 1880 1890 1900
EGSPGVGKTS LITAIANASG NQIVRINLSE QTDIMDLLGS DLPVEGGTGG
1910 1920 1930 1940 1950
QFEWRDGVFL EALRNGSWVL LDELNLASQT VLEGLNSCLD HRSEVYIPEL
1960 1970 1980 1990 2000
GKTFACHPNF RVFACQNPLH QGGGRKGLPK SFLNRFTQVF IDQLNQQDLL
2010 2020 2030 2040 2050
FISTAMYPTI PSKTIERMIE FNHQMFKESM IEHKFARKGA PWEFNLRDTF
2060 2070 2080 2090 2100
RWCDLIVKDP TSISNPARFI DLIYLQRMRT LQDREHVLTI FKRVFTTSGD
2110 2120 2130 2140 2150
ENDQSIDMMP TICNYDKQPH YSISPEYLQI GSSILPRVQN GGASSFDSSV
2160 2170 2180 2190 2200
LDNSSNIQLL QRLLNPLENI MKCIEMNWMS ILIGPTSTSK TSSIRLLAQL
2210 2220 2230 2240 2250
TGNTLYEFSM NSSVDTTEIL GGFEQIDLVR YQKRIISSVS SLITIVSSHI
2260 2270 2280 2290 2300
MTYFNSNDDN LMKTCISSIQ DIHQVWNLFK KQTQQTQQQI QQDGATIGSG
2310 2320 2330 2340 2350
GVGLITIEQL DLLSTIVDAL EKLSIQFNLD NNQEHLNRIQ DVRQQIQRIK
2360 2370 2380 2390 2400
SIEKESVTGC FEWIDGLLIK ALETGAWILI DNVNFCNPTV LDRLNPLLEQ
2410 2420 2430 2440 2450
DGVLMLNERG MVDGQVKVVK PHPNFRIFLT MDDKKGEISR AMRNRGIEIY
2460 2470 2480 2490 2500
MAADQLSLME TPSNNFDNQQ LLTALGIPLE SLTRTMIDFH NQIFTQLSST
2510 2520 2530 2540 2550
IENPCTLSQL LYWGKLILDQ LQRGFSLLNS IRNSMEQIYI RPRRHLTQRQ
2560 2570 2580 2590 2600
LVTNIFNSIF NESAIKSILC EDQTVLGIYP HFIKGKDYVT DSISTTMKMN
2610 2620 2630 2640 2650
YQFFEYYLKR LMNSLSSSSS SSSQQQQQDE SNYKISAKFL IENINSSQYE
2660 2670 2680 2690 2700
NYVLYLNSLK DQNEKDSPIN QLLTTLISCM KQLFNHTCYK DFEKRLEQLL
2710 2720 2730 2740 2750
SMINLSFIDS KQLLIYQGHQ WKNNDSLFLL IKEKVDNYIT KEAGGSESMI
2760 2770 2780 2790 2800
PIKDLFNQVL LNDMEIIKSL LSLFIQSSKQ EKEYNKFLKQ VQQGNASQQL
2810 2820 2830 2840 2850
SVKSIKSIPV ILLSLAYTKK MMSKDLLPHQ DIISMIYRLF KSLDEQIDQW
2860 2870 2880 2890 2900
LIQLSSSEQQ QSTFSTIQII NQLILLKNNF WNSTFNLPSN QFNLGEFIIR
2910 2920 2930 2940 2950
WRWIYKEINK LTTLTSKSES PLLINTGLQV LIDKISSGLN QYNNDNSNNR
2960 2970 2980 2990 3000
LWKVGGYPMV MKSNHLVQLD SQFLSILEKV QYNFNKNESP IKHSSYAIDE
3010 3020 3030 3040 3050
DWKKTLIEAI STLYWANYQL NSDNQNQEQQ QQELDRVSEF LTNLELVPQT
3060 3070 3080 3090 3100
LSDKLKQLIE KQKQFELNST FNPVSTNFDN SDISNDSMIS DATSIHFDPL
3110 3120 3130 3140 3150
SIKHQVISIS PLIDHSLHLK ETFVISELVK LLMLQHMDIE NGKMNQSIIT
3160 3170 3180 3190 3200
IFESIIDELK YIVNKYKSST IPRSLYHLAF YQKLIWMIDN YLEKVTTNQE
3210 3220 3230 3240 3250
KDEQGQEQEQ ASIGIIELQS VIHSILYVYN SSQWNNAFND ISHVGKYSLP
3260 3270 3280 3290 3300
QYKYRLSKND AAASLDNGSS KVNIYDSIRF GYGPPRLFQN IQTVFSFYLT
3310 3320 3330 3340 3350
CDWEYVSIAD VPVKIEQLNQ IIQHLTSADG SSNVSNIESF EYQIKQTIAL
3360 3370 3380 3390 3400
LLSTITSFYK SFNNDEHKKH QLLSNVALIG EHLLSSSSSL EILDIGFDEL
3410 3420 3430 3440 3450
IENIKELIIQ SNDKSFNEKS KQLLLPCLDI LLCLDDKVLY KDELKLQSTF
3460 3470 3480 3490 3500
GRLQLLLNTF RLIMFVPSGS IDPTQKYDVI LQYSKEHSKQ LQDEIEIRTI
3510 3520 3530 3540 3550
IEKQYTGKDG TSLVIDELVQ KKQSIDQKLA LDSKKITLRP IPSQFEELYR
3560 3570 3580 3590 3600
DVSQFSNHFS NIEKIIDLIS KLDLSQVKNE FNLEVESEGG DNQQQQENNT
3610 3620 3630 3640 3650
SANSSYNQMI LSTEQMWQEK ANHFIQSCEK KFYSRYRDII VPIITAVYQM
3660 3670 3680 3690 3700
KSGLRMMSVS FKQKVQDNKL GGNQGITKQI QKVLLSLTQF PRINSVDINS
3710 3720 3730 3740 3750
KITTTSTTTT ATTTTNTTSN NILLDKLTLD SIKDMMKFNQ RTNQDNCNGG
3760 3770 3780 3790 3800
LQNFKVIGLL LRSSLCQIYS QLSNSNYLDV DNLEAIDSIF RIFVQEWRFQ
3810 3820 3830 3840 3850
EEEKRKKEEL ENQEFKYKVQ THKMETKEEK DEKVFLTSFP NFYKDFEDLE
3860 3870 3880 3890 3900
VANVVENQID DDNDEENKDK ENNESNVLTS EDGSMFFKSS INNEEILQLC
3910 3920 3930 3940 3950
SIHRDIFKHL DGIPIPKEQQ QWTLSDRDRS ELFQLFYSSS YLLMKILNQR
3960 3970 3980 3990 4000
SGDMEFDQLS LGSHILSASN LKETLSIRPP SLITYSKLDE KFRFLKTSSY
4010 4020 4030 4040 4050
LYKKSKGIND DDGDNQVVDV IHQKKTYNIY RDSNISEIGI IREPLISFRK
4060 4070 4080 4090 4100
RVFELLVEYP EQANLTLMVK LIDRLMTYPA TDPLAKILTG LELLLRKSLE
4110 4120 4130 4140 4150
WESFASKAVS IQNHLNEISS LIVRWRKLEI ESWPSIFQSQ EKEAEVKALK
4160 4170 4180 4190 4200
SWFILYDLIN DEPSSPELED ENLSKNFHTL QQYLYSSSLG DFLTRIELLK
4210 4220 4230 4240 4250
SFYKQLNSTI KLIGTSKNTN YKQKLSDIIY NIFKYFENFI SRFEDRLAKS
4260 4270 4280 4290 4300
IKPIEDKALE FIRLSRWDDN RLLTQYERLK QHIEVSHRNL AKVTIKYKNV
4310 4320 4330 4340 4350
LAQPLHDIFT QIENELDIPP LVLHSGAATI LEDKLKKNQK LNKKQIQKKS
4360 4370 4380 4390 4400
LAIENFNDWL SFSPSNYSID RKSIDSISKP IEIESPLLKK LFQIENEKLA
4410 4420 4430 4440 4450
QNKLSLLSKR MIQICKENLL ESDSWKVVRD GVDIINDLSI EIIDRLKELS
4460 4470 4480 4490 4500
SDEKIKRQEK EFALKELMSK FHEMGLSYHI NRYPQEQLQI SYLFNVRHLP
4510 4520 4530 4540 4550
TISDNQGYLP TSFSKITADN GAKLLDQADQ YYYRIVSRVH RLRQLSIEYN
4560 4570 4580 4590 4600
SDLSSKHVQR INGYVEHFLS IIINQRNNLI DSINSWNHLT LFTELFTNIS
4610 4620 4630 4640 4650
GSGGSNSEID EQIFNNHNML SKWFEIQRES INQFNQAIKE ILLLCRKTTS
4660 4670 4680 4690 4700
AVSGGMISTI IPEICSIQII IESIKSEIDK HQSKLRNLFS FLNNQYPMMT
4710 4720 4730 4740 4750
WSTINLIISI FTKFKEIKEK LNQLLLSKLS NINYIKSPIQ ILINNIDSLI
4760 4770 4780 4790 4800
NKFNSEYEEL VGNEINDNDI ENQNNIKEFT NQFGILIDQI LISIQDLKIQ
4810 4820 4830 4840 4850
SNQIIAYNKE QEELDQELEK VREYTIEDGS ISKLSEFIDH QVQSLRLSKL
4860 4870 4880 4890 4900
LEQFVKLHNI IVDGGGSVST LSIYRQMIKQ MGPLLAQFML IVNQSIVDSL
4910 4920 4930 4940 4950
SYHKTCCKLE YISTGVFIQL YSKGFCKPAD GGDDGEGGEG GRSNFEDDVE
4960 4970 4980 4990 5000
GTGMGEGKGK KDVSDQLEDQ GQIEDTNTQK KEEKDEDEDE EKEEKDEDEG
5010 5020 5030 5040 5050
FDMQDDFEGE MHDIKKDENK DEDKKDDPNN EKENDKEMGD LEKPEDNVVD
5060 5070 5080 5090 5100
EKLWDEQDVQ DEEEQDEEGK GDETNSEEMM AKQDGKDDND DDKKDDDKKD
5110 5120 5130 5140 5150
DKKKKKEENG KPDENEEGEE GKDDEEEDGK DDNKNADDGA SDEDDFGQEE
5160 5170 5180 5190 5200
NEDDVINQEQ EKEENHGDPR GDDQMEIPED LELEDPDEGK EDDEQQDGGD
5210 5220 5230 5240 5250
DFKDPLDEMD GDDVSKEEEK KKELDGDEKE ESDQDGDEEK EDEEKEDGDE
5260 5270 5280 5290 5300
DEDKEDKENQ PIDPSNVDSI NPEGDEPEKE QPEEDQTSLT TNEQQDETPK
5310 5320 5330 5340 5350
DSEQPLGVKD KTGSKSNVSN TDEEMKDESN QDNADDDSGM TQPTPSENDT
5360 5370 5380 5390 5400
GALKNLKSQP PPQSSAQQPP KKQKQVDPNP YRSMGDANKE WKKRLNLKQE
5410 5420 5430 5440 5450
QEEEEEEQSS EPKEKAPKQD PNAKENENQD YEFIKDDEKL DKDEETDQAL
5460 5470 5480 5490 5500
AAATDTQLQD IPQNKAQDDQ AEQEEDQMDI DEEDDMDVDH KQEVEHQDDS
5510 5520 5530 5540 5550
KQQLDENKKI SMSKLKQDQL KQQKEKEKEK LEKDQQDGQD DELDGLNQKE
5560 5570 5580 5590 5600
QFTKEQLENL TNLDKEKAVL DDGDDQEMEQ DGDQDDEESV EEKKLTREDL
5610 5620 5630 5640 5650
DRMRQELEQY KIENSSNPEI GTELWKKYEQ LTNDLSQDLC EQLRLILEPT
5660 5670 5680 5690 5700
LATKLQGDYK SGKRINMKKV IPYIASQFKK DKIWLRRTKP NKRQYQVLLA
5710 5720 5730 5740 5750
IDDTESMAAY HSGGFALEAM TMISRAMSRL EVGQLGIVRF GEDVQLVHSF
5760 5770 5780 5790 5800
DQVFSDQTGP EIITQFKFQQ TKTNMVNFLS KTLQIMDMNK QSSSGEPAMQ
5810 5820 5830 5840 5850
LVFIVSDGWS LRDPETTKKY LREASIKNVF IVFIVIDNPV NNNSILDFES
5860 5870 5880 5890 5900
ISFNNGKIQR TNYMSEFPFM YYVILRSLNN IPSILSDTLR QWFDLTKSTQ
Length:5,900
Mass (Da):678,735
Last modified:February 10, 2009 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3C6947787C12C771
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAFI02000013 Genomic DNA Translation: EEU04125.1

NCBI Reference Sequences

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RefSeqi
XP_002649177.1, XM_002649131.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
EEU04125; EEU04125; DDB_G0295765

Database of genes from NCBI RefSeq genomes

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GeneIDi
8620042

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ddi:DDB_G0295765

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000013 Genomic DNA Translation: EEU04125.1
RefSeqiXP_002649177.1, XM_002649131.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi44689.DDB0252730

Proteomic databases

PaxDbiQ869L3
PRIDEiQ869L3

Genome annotation databases

EnsemblProtistsiEEU04125; EEU04125; DDB_G0295765
GeneIDi8620042
KEGGiddi:DDB_G0295765

Organism-specific databases

dictyBaseiDDB_G0295765, mdn1

Phylogenomic databases

eggNOGiKOG1808, Eukaryota
HOGENOMiCLU_000050_0_2_1
InParanoidiQ869L3
OMAiELGPPNI
PhylomeDBiQ869L3

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q869L3

Family and domain databases

Gene3Di3.40.50.300, 5 hits
3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR003593, AAA+_ATPase
IPR040848, AAA_lid_7
IPR011704, ATPase_dyneun-rel_AAA
IPR012099, Midasin
IPR041190, Midasin_AAA_lid_5
IPR027417, P-loop_NTPase
IPR025662, Sigma_54_int_dom_ATP-bd_1
IPR002035, VWF_A
IPR036465, vWFA_dom_sf
PfamiView protein in Pfam
PF07728, AAA_5, 8 hits
PF17865, AAA_lid_5, 1 hit
PF17867, AAA_lid_7, 3 hits
PIRSFiPIRSF010340, Midasin, 1 hit
SMARTiView protein in SMART
SM00382, AAA, 5 hits
SM00327, VWA, 1 hit
SUPFAMiSSF52540, SSF52540, 6 hits
SSF53300, SSF53300, 1 hit
PROSITEiView protein in PROSITE
PS00675, SIGMA54_INTERACT_1, 1 hit
PS50234, VWFA, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMDN1_DICDI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q869L3
Secondary accession number(s): C7FZZ7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: February 10, 2009
Last modified: September 29, 2021
This is version 96 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families
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