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Entry version 84 (11 Dec 2019)
Sequence version 1 (01 Jun 2003)
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Protein

Multidrug resistance-associated protein 1

Gene

ABCC1

Organism
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export (PubMed:12657726). Hydrolyzes ATP with low efficiency. Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation (By similarity). Participates in inflammatory response by allowing export of leukotriene C4 from leukotriene C4-synthezing cells (By similarity).By similarity1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • ATP + H(2)O + xenobiotic(Side 1) = ADP + phosphate + xenobiotic(Side 2).1 Publication EC:7.6.2.2

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

MK 571 inhibits sphingosine 1-phosphate and leukotriene C4 export.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi678 – 685ATP 1PROSITE-ProRule annotation8
Nucleotide bindingi1327 – 1334ATP 2PROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Translocase
Biological processTransport
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Multidrug resistance-associated protein 1By similarity (EC:7.6.2.21 Publication)
Alternative name(s):
ATP-binding cassette sub-family C member 1
Glutathione-S-conjugate-translocating ATPase ABCC1By similarity (EC:7.6.2.3By similarity)
Leukotriene C(4) transporter
Short name:
LTC4 transporter
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ABCC1By similarity
Synonyms:MRP1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMacaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9541 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000233100 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 33ExtracellularBy similarityAdd BLAST33
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei34 – 54Helical; Name=1PROSITE-ProRule annotationAdd BLAST21
Topological domaini55 – 74CytoplasmicBy similarityAdd BLAST20
Transmembranei75 – 95Helical; Name=2PROSITE-ProRule annotationAdd BLAST21
Topological domaini96 – 100ExtracellularBy similarity5
Transmembranei101 – 121Helical; Name=3PROSITE-ProRule annotationAdd BLAST21
Topological domaini122 – 133CytoplasmicBy similarityAdd BLAST12
Transmembranei134 – 154Helical; Name=4PROSITE-ProRule annotationAdd BLAST21
Topological domaini155 – 172ExtracellularBy similarityAdd BLAST18
Transmembranei173 – 193Helical; Name=5PROSITE-ProRule annotationAdd BLAST21
Topological domaini194 – 316CytoplasmicBy similarityAdd BLAST123
Transmembranei317 – 337Helical; Name=6PROSITE-ProRule annotationAdd BLAST21
Topological domaini338 – 363ExtracellularBy similarityAdd BLAST26
Transmembranei364 – 384Helical; Name=7PROSITE-ProRule annotationAdd BLAST21
Topological domaini385 – 440CytoplasmicBy similarityAdd BLAST56
Transmembranei441 – 461Helical; Name=8PROSITE-ProRule annotationAdd BLAST21
Topological domaini462 – 464ExtracellularBy similarity3
Transmembranei465 – 485Helical; Name=9PROSITE-ProRule annotationAdd BLAST21
Topological domaini486 – 547CytoplasmicBy similarityAdd BLAST62
Transmembranei548 – 568Helical; Name=10PROSITE-ProRule annotationAdd BLAST21
Topological domaini569 – 590ExtracellularBy similarityAdd BLAST22
Transmembranei591 – 611Helical; Name=11PROSITE-ProRule annotationAdd BLAST21
Topological domaini612 – 967CytoplasmicBy similarityAdd BLAST356
Transmembranei968 – 988Helical; Name=12PROSITE-ProRule annotationAdd BLAST21
Topological domaini989 – 1025ExtracellularBy similarityAdd BLAST37
Transmembranei1026 – 1046Helical; Name=13PROSITE-ProRule annotationAdd BLAST21
Topological domaini1047 – 1089CytoplasmicBy similarityAdd BLAST43
Transmembranei1090 – 1110Helical; Name=14PROSITE-ProRule annotationAdd BLAST21
Topological domaini1111ExtracellularBy similarity1
Transmembranei1112 – 1132Helical; Name=15PROSITE-ProRule annotationAdd BLAST21
Topological domaini1133 – 1203CytoplasmicBy similarityAdd BLAST71
Transmembranei1204 – 1224Helical; Name=16PROSITE-ProRule annotationAdd BLAST21
Topological domaini1225 – 1226ExtracellularBy similarity2
Transmembranei1227 – 1247Helical; Name=17PROSITE-ProRule annotationAdd BLAST21
Topological domaini1248 – 1531CytoplasmicBy similarityAdd BLAST284

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000933521 – 1531Multidrug resistance-associated protein 1Add BLAST1531

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi19N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei277PhosphotyrosineBy similarity1
Modified residuei289PhosphoserineBy similarity1
Modified residuei503N6-succinyllysineBy similarity1
Modified residuei905PhosphoserineBy similarity1
Modified residuei915PhosphoserineBy similarity1
Modified residuei930PhosphoserineBy similarity1
Glycosylationi1006N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q864R9

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9541.XP_005591397.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q864R9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini325 – 608ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST284
Domaini644 – 868ABC transporter 1PROSITE-ProRule annotationAdd BLAST225
Domaini975 – 1256ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST282
Domaini1293 – 1527ABC transporter 2PROSITE-ProRule annotationAdd BLAST235

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

KEGG Orthology (KO)

More...
KOi
K05665

Database of Orthologous Groups

More...
OrthoDBi
138195at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1560.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR005292 Multidrug-R_assoc
IPR027417 P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382 AAA, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00957 MRP_assoc_pro, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 2 hits
PS50893 ABC_TRANSPORTER_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q864R9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALRGFCSAD GSDPLWDWNV TWYTSNPDFT KCFQNTVLVW VPCFYLWACF
60 70 80 90 100
PFYFLYLSRH DRGYIQMTLL NKTKTALGFL LWIVCWADLF YSFWERSRGI
110 120 130 140 150
FLAPVFLVSP TLLGITMLLA TFLIQLERRK GVQSSGIMLT FWLVALLCAL
160 170 180 190 200
AILRSKIMTA LKEDVQVDLF RDMTFYVYFS LVLIQLVLSC FSDRSPLFSE
210 220 230 240 250
TIHDPNPCPE SSASFLSRIT FWWITGLIVR GYRQPLEGSD LWSLNKEDTS
260 270 280 290 300
EQVVPVLVKN WKKECAKTRK QPVKVVYSSK DPAQPKDSSK VDANEEVEAL
310 320 330 340 350
IVKSPQKEWN PSLFKVLYKT FGPYFLMSFF FKAIHDLMMF SGPEILKLLI
360 370 380 390 400
NFVNDTKAPD WQGYFYTALL FVAACLQTLV LHQYFHICFV SGMRIKTAVI
410 420 430 440 450
GAVYRKALVI TNAARKSSTV GEIVNLMSVD AQRFMDLATY INMIWSAPLQ
460 470 480 490 500
VILALYLLWR NLGPPILAGV AVMVLMVPVN AVMAMKTKTY QVAHMKSKDN
510 520 530 540 550
RIKLMNEILN GIKVLKLYAW ELAFKDKVLA IRQEELKVLK KSAYLAAVGT
560 570 580 590 600
FTWVCTPFLV ALCTFAVYVT IDKNNVLDAQ KAFVSLALFN ILRFPLNILP
610 620 630 640 650
MVISSIVQAS VSLKRLRIFL SHEELEPDSI ERRPVKDGGD TNSITVRNAT
660 670 680 690 700
FTWARSDPPT LNGITFSIPE GALVAVVGQV GCGKSSLLSA LLAEMDKVEG
710 720 730 740 750
HVALKGSVAY VPQQAWIQND SLQENILFGC QLEEPYYRSV IQACALLPDL
760 770 780 790 800
EILPSGDRTE IGEKGVNLSG GQKQRVSLAR AVYCNADIYL FDDPLSAVDA
810 820 830 840 850
HVGKHIFENV IGPKGMLKNK TRILVTHSMS YLPQVDVIIV MSGGKISEMG
860 870 880 890 900
SYQELLARDG AFAEFLRTYA SAEQEQDPED NGVTGVSGPG KEAKQMENGM
910 920 930 940 950
LVTDSAGKQL QRQLSSSSSY SGDVSRQHNS TAELQKDGAK KEETWKLMEA
960 970 980 990 1000
DKAQTGQVKL SVYWDYMKAI GLFISFLSIF LFICNHVAAL ASNYWLSLWT
1010 1020 1030 1040 1050
DDPIVNGTQE HTKVRLSVYG ALGISQGIAV FGYSMAVSIG GILASRCLHV
1060 1070 1080 1090 1100
DLLHSILRSP MSFFERTPSG NLVNRFSKEL DTVDSMIPEV IKMFMGSLFN
1110 1120 1130 1140 1150
VIGACIVILL ATPIAAIIIP PLGLIYFFVQ RFYVASSRQL KRLESVSRSP
1160 1170 1180 1190 1200
VYSHFNETLL GVSVIRAFEE QERFIHQSDL KVDENQKAYY PSIVANRWLA
1210 1220 1230 1240 1250
VRLECVGNCI VLFAALFAVI SRHSLSAGLV GLSVSYSLQV TTYLNWLVRM
1260 1270 1280 1290 1300
SSEMETNIVA VERLKEYSET EKEAPWQIQE TAPPSNWPQV GRVEFRNYCL
1310 1320 1330 1340 1350
RYREDLDFVL RHINVTINGG EKVGIVGRTG AGKSSLTLGL FRINESAEGE
1360 1370 1380 1390 1400
IIIDGINIAR IGLHDLRFKI TIIPQDPVLF SGSLRMNLDP FSQYSDEEVW
1410 1420 1430 1440 1450
TSLELAHLKG FVSALPDKLD HECAEGGENL SVGQRQLVCL ARALLRKTKI
1460 1470 1480 1490 1500
LVLDEATAAV DLETDDLIQS TIRTQFEDCT VLTIAHRLNT IMDYTRVIVL
1510 1520 1530
DKGEIQEYGA PSDLLQQRGL FYNMARDAGL V
Length:1,531
Mass (Da):171,659
Last modified:June 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1AE788EFDF9EF459
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti173M → I1 Publication1
Natural varianti704L → I1 Publication1
Natural varianti1047C → Y1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY146672 mRNA Translation: AAN65348.1
AY146673 mRNA Translation: AAN65349.1

NCBI Reference Sequences

More...
RefSeqi
NP_001271100.1, NM_001284171.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
102133648

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mcf:102133648

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY146672 mRNA Translation: AAN65348.1
AY146673 mRNA Translation: AAN65349.1
RefSeqiNP_001271100.1, NM_001284171.1

3D structure databases

SMRiQ864R9
ModBaseiSearch...

Protein-protein interaction databases

STRINGi9541.XP_005591397.1

Proteomic databases

PRIDEiQ864R9

Genome annotation databases

GeneIDi102133648
KEGGimcf:102133648

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
4363

Phylogenomic databases

KOiK05665
OrthoDBi138195at2759

Family and domain databases

Gene3Di1.20.1560.10, 2 hits
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR005292 Multidrug-R_assoc
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits
TIGRFAMsiTIGR00957 MRP_assoc_pro, 1 hit
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 2 hits
PS50893 ABC_TRANSPORTER_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMRP1_MACFA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q864R9
Secondary accession number(s): Q864S0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: June 1, 2003
Last modified: December 11, 2019
This is version 84 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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