Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 94 (16 Jan 2019)
Sequence version 1 (01 Nov 1996)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein
Submitted name:

Apoptosis regulator M11L

Gene

M11L

Organism
Myxoma virus
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Apoptosis regulator M11LImported
Submitted name:
M11L proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:M11LImported
ORF Names:m011LImported, MYXV_gp015Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMyxoma virusImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10273 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeLeporipoxvirus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000096711 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome
  • UP000160630 Componenti: Genome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei143 – 163HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi21 ↔ 28Combined sources
Disulfide bondi33 ↔ 127Combined sources

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2JBXX-ray2.73A/B1-132[»]
2JBYX-ray2.41A2-132[»]
2O42X-ray2.91A/B1-142[»]

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q85295

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

Database of Orthologous Groups

More...
OrthoDBi
26048at10239

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.437.40, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR038278 F1/C10_sf
IPR020361 Poxvirus_C10
IPR021119 Poxvirus_F1/C10

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF11099 M11L, 1 hit

ProDom; a protein domain database

More...
ProDomi
View protein in ProDom or Entries sharing at least one domain
PD097040 Uncharacterised_C10, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q85295-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMSRLKTAVY DYLNDVDITE CTEMDLLCQL SNCCDFINET YAKNYDTLYD
60 70 80 90 100
IMERDILSYN IVNIKNTLTF ALRDASPSVK LATLTLLASV IKKLNKIQHT
110 120 130 140 150
DAAMFSEVID GIVAEEQQVI GFIQKKCKYN TTYYNVRSGG CKISVYLTAA
160
VVGFVAYGIL KWYRGT
Length:166
Mass (Da):18,813
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i31A4C719F1E2A3F9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M93049 Genomic DNA Translation: AAA46628.1
EU552530 Genomic DNA Translation: ACB28633.1
JX565562 Genomic DNA Translation: AFU76944.1
JX565563 Genomic DNA Translation: AFU77110.1
JX565564 Genomic DNA Translation: AFU77276.1
JX565565 Genomic DNA Translation: AFU77443.1
JX565566 Genomic DNA Translation: AFU77612.1
JX565567 Genomic DNA Translation: AFU77781.1
JX565568 Genomic DNA Translation: AFU77945.1
JX565569 Genomic DNA Translation: AFU78113.1
JX565570 Genomic DNA Translation: AFU78281.1
JX565571 Genomic DNA Translation: AFU78445.1
JX565572 Genomic DNA Translation: AFU78614.1
JX565573 Genomic DNA Translation: AFU78780.1
JX565574 Genomic DNA Translation: AFU78947.1
JX565575 Genomic DNA Translation: AFU79113.1
JX565576 Genomic DNA Translation: AFU79280.1
JX565577 Genomic DNA Translation: AFU79448.1
JX565578 Genomic DNA Translation: AFU79614.1
JX565579 Genomic DNA Translation: AFU79781.1
JX565580 Genomic DNA Translation: AFU79947.1
JX565581 Genomic DNA Translation: AFU80114.1
JX565582 Genomic DNA Translation: AFU80281.1
JX565583 Genomic DNA Translation: AFU80448.1
JX565584 Genomic DNA Translation: AFU80616.1
KC660079 Genomic DNA Translation: AGW25804.1
KC660080 Genomic DNA Translation: AGW25971.1
KC660081 Genomic DNA Translation: AGW26140.1
KC660082 Genomic DNA Translation: AGW26308.1
KC660083 Genomic DNA Translation: AGW26475.1
KC660084 Genomic DNA Translation: AGW26643.1
KC660085 Genomic DNA Translation: AGW26810.1
KP723386 Genomic DNA Translation: AMB17516.1
KP723388 Genomic DNA Translation: AMB17844.1
KP723389 Genomic DNA Translation: AMB18011.1
KP723390 Genomic DNA Translation: AMB18181.1
KY548791 Genomic DNA Translation: AQT34161.1
KY548792 Genomic DNA Translation: AQT34331.1
KY548793 Genomic DNA Translation: AQT34501.1
KY548794 Genomic DNA Translation: AQT34671.1
KY548795 Genomic DNA Translation: AQT34841.1
KY548796 Genomic DNA Translation: AQT35011.1
KY548797 Genomic DNA Translation: AQT35181.1
KY548798 Genomic DNA Translation: AQT35351.1
KY548799 Genomic DNA Translation: AQT35521.1
KY548800 Genomic DNA Translation: AQT35691.1
KY548801 Genomic DNA Translation: AQT35861.1
KY548802 Genomic DNA Translation: AQT36031.1
KY548803 Genomic DNA Translation: AQT36201.1
KY548804 Genomic DNA Translation: AQT36371.1
KY548805 Genomic DNA Translation: AQT36541.1
KY548806 Genomic DNA Translation: AQT36711.1
KY548807 Genomic DNA Translation: AQT36881.1
KY548808 Genomic DNA Translation: AQT37051.1
KY548809 Genomic DNA Translation: AQT37221.1
KY548810 Genomic DNA Translation: AQT37391.1
KY548811 Genomic DNA Translation: AQT37561.1
KY548812 Genomic DNA Translation: AQT37731.1
KY548813 Genomic DNA Translation: AQT37901.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A44058

NCBI Reference Sequences

More...
RefSeqi
NP_051725.1, NC_001132.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
932150

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
vg:932150

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M93049 Genomic DNA Translation: AAA46628.1
EU552530 Genomic DNA Translation: ACB28633.1
JX565562 Genomic DNA Translation: AFU76944.1
JX565563 Genomic DNA Translation: AFU77110.1
JX565564 Genomic DNA Translation: AFU77276.1
JX565565 Genomic DNA Translation: AFU77443.1
JX565566 Genomic DNA Translation: AFU77612.1
JX565567 Genomic DNA Translation: AFU77781.1
JX565568 Genomic DNA Translation: AFU77945.1
JX565569 Genomic DNA Translation: AFU78113.1
JX565570 Genomic DNA Translation: AFU78281.1
JX565571 Genomic DNA Translation: AFU78445.1
JX565572 Genomic DNA Translation: AFU78614.1
JX565573 Genomic DNA Translation: AFU78780.1
JX565574 Genomic DNA Translation: AFU78947.1
JX565575 Genomic DNA Translation: AFU79113.1
JX565576 Genomic DNA Translation: AFU79280.1
JX565577 Genomic DNA Translation: AFU79448.1
JX565578 Genomic DNA Translation: AFU79614.1
JX565579 Genomic DNA Translation: AFU79781.1
JX565580 Genomic DNA Translation: AFU79947.1
JX565581 Genomic DNA Translation: AFU80114.1
JX565582 Genomic DNA Translation: AFU80281.1
JX565583 Genomic DNA Translation: AFU80448.1
JX565584 Genomic DNA Translation: AFU80616.1
KC660079 Genomic DNA Translation: AGW25804.1
KC660080 Genomic DNA Translation: AGW25971.1
KC660081 Genomic DNA Translation: AGW26140.1
KC660082 Genomic DNA Translation: AGW26308.1
KC660083 Genomic DNA Translation: AGW26475.1
KC660084 Genomic DNA Translation: AGW26643.1
KC660085 Genomic DNA Translation: AGW26810.1
KP723386 Genomic DNA Translation: AMB17516.1
KP723388 Genomic DNA Translation: AMB17844.1
KP723389 Genomic DNA Translation: AMB18011.1
KP723390 Genomic DNA Translation: AMB18181.1
KY548791 Genomic DNA Translation: AQT34161.1
KY548792 Genomic DNA Translation: AQT34331.1
KY548793 Genomic DNA Translation: AQT34501.1
KY548794 Genomic DNA Translation: AQT34671.1
KY548795 Genomic DNA Translation: AQT34841.1
KY548796 Genomic DNA Translation: AQT35011.1
KY548797 Genomic DNA Translation: AQT35181.1
KY548798 Genomic DNA Translation: AQT35351.1
KY548799 Genomic DNA Translation: AQT35521.1
KY548800 Genomic DNA Translation: AQT35691.1
KY548801 Genomic DNA Translation: AQT35861.1
KY548802 Genomic DNA Translation: AQT36031.1
KY548803 Genomic DNA Translation: AQT36201.1
KY548804 Genomic DNA Translation: AQT36371.1
KY548805 Genomic DNA Translation: AQT36541.1
KY548806 Genomic DNA Translation: AQT36711.1
KY548807 Genomic DNA Translation: AQT36881.1
KY548808 Genomic DNA Translation: AQT37051.1
KY548809 Genomic DNA Translation: AQT37221.1
KY548810 Genomic DNA Translation: AQT37391.1
KY548811 Genomic DNA Translation: AQT37561.1
KY548812 Genomic DNA Translation: AQT37731.1
KY548813 Genomic DNA Translation: AQT37901.1
PIRiA44058
RefSeqiNP_051725.1, NC_001132.2

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2JBXX-ray2.73A/B1-132[»]
2JBYX-ray2.41A2-132[»]
2O42X-ray2.91A/B1-142[»]
SMRiQ85295
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi932150
KEGGivg:932150

Phylogenomic databases

OrthoDBi26048at10239

Family and domain databases

Gene3Di1.10.437.40, 1 hit
InterProiView protein in InterPro
IPR038278 F1/C10_sf
IPR020361 Poxvirus_C10
IPR021119 Poxvirus_F1/C10
PfamiView protein in Pfam
PF11099 M11L, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD097040 Uncharacterised_C10, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ85295_9POXV
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q85295
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: January 16, 2019
This is version 94 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again