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Entry version 93 (11 Dec 2019)
Sequence version 1 (01 Jun 2003)
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Protein
Submitted name:

Protomycinolide IV synthase 5

Gene

mycAV

Organism
Micromonospora griseorubida
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
MetaCyc:MONOMER-18363

Protein family/group databases

ESTHER database of the Alpha/Beta-hydrolase fold superfamily of proteins

More...
ESTHERi
micgr-MYCAV Thioesterase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Protomycinolide IV synthase 5Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mycAVImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMicromonospora griseorubidaImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28040 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaMicromonosporalesMicromonosporaceaeMicromonospora

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1734O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

PhosphopantetheinePROSITE-ProRule annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1699 – 1774CarrierInterPro annotationAdd BLAST76

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili13 – 33Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1200.10, 1 hit
3.10.129.110, 1 hit
3.40.366.10, 1 hit
3.40.47.10, 1 hit
3.40.50.1820, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029058 AB_hydrolase
IPR001227 Ac_transferase_dom_sf
IPR036736 ACP-like_sf
IPR014043 Acyl_transferase
IPR016035 Acyl_Trfase/lysoPLipase
IPR032821 KAsynt_C_assoc
IPR018201 Ketoacyl_synth_AS
IPR014031 Ketoacyl_synth_C
IPR014030 Ketoacyl_synth_N
IPR016036 Malonyl_transacylase_ACP-bd
IPR036291 NAD(P)-bd_dom_sf
IPR041314 PikA4_N
IPR020801 PKS_acyl_transferase
IPR020841 PKS_Beta-ketoAc_synthase_dom
IPR020807 PKS_dehydratase
IPR042104 PKS_dehydratase_sf
IPR013968 PKS_KR
IPR020806 PKS_PP-bd
IPR020802 PKS_thioesterase
IPR009081 PP-bd_ACP
IPR006162 Ppantetheine_attach_site
IPR001031 Thioesterase
IPR016039 Thiolase-like

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00698 Acyl_transf_1, 1 hit
PF16197 KAsynt_C_assoc, 1 hit
PF00109 ketoacyl-synt, 1 hit
PF02801 Ketoacyl-synt_C, 1 hit
PF08659 KR, 1 hit
PF18605 PikAIV_N, 1 hit
PF00550 PP-binding, 1 hit
PF14765 PS-DH, 1 hit
PF00975 Thioesterase, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00827 PKS_AT, 1 hit
SM00826 PKS_DH, 1 hit
SM00825 PKS_KS, 1 hit
SM00823 PKS_PP, 1 hit
SM00824 PKS_TE, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51735 SSF51735, 2 hits
SSF52151 SSF52151, 1 hit
SSF53474 SSF53474, 1 hit
SSF53901 SSF53901, 1 hit
SSF55048 SSF55048, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00606 B_KETOACYL_SYNTHASE, 1 hit
PS50075 CARRIER, 1 hit
PS00012 PHOSPHOPANTETHEINE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q83WE6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTTTSPDRLL EALRSALKEG DRLRSQLRQM TEAQTEPIAI IGMACRYPGG
60 70 80 90 100
ADTPDELWNV VAAGRDAVGP FPTDRGWDLD RICHPDPDVP GTTYCREGGF
110 120 130 140 150
VYDAAEFDAA FFGISPREAT AMDPQQRLLL EVSWEALEDA ALDPLSVRGT
160 170 180 190 200
RTGVFVGAAH QDYVTEADQV PEGTEGYLLT GTTDAVLSGR LSYVFGLEGP
210 220 230 240 250
AVTVATACSS SLVALHLAVQ SLRRGECGMA LAGGVSVSVT PAAFVEFARQ
260 270 280 290 300
RGLAPDGRCK SFADAADGTG WAEGVGVVVL EPLTVALRHN RRVLAVVRGS
310 320 330 340 350
AGEPGRRQNG LTAPNGLAHE KVIRAALADA RLGAEQVDAV EAHGTGTRLG
360 370 380 390 400
DPIEAEALLA TYGQGRPEGR PLWLGSVKSN IGHAQAAAGI GGVIKMVQAM
410 420 430 440 450
RHGVLPKTLH VDAPSRHVAW SSGQVRLLTE TVPWPAGGEP RRAGVSAFGV
460 470 480 490 500
SGTNAHVILE HLPPEERTGP DTPERERTAC RGYRSCPGSC RPAPSRVRAQ
510 520 530 540 550
AARWRAQLDR ADPPRLVDVG FSLATTRAPL SHRSVLLCGD PAELLDAVAE
560 570 580 590 600
GREHPAVVRG TPERTDRLGF LFTGQGAQRA GMARELYASL PVFTQAFDEV
610 620 630 640 650
VDLLDGHLDR PLKTVLFAEA GTASVELLDR TGHAQPALFA VEVALFRTLE
660 670 680 690 700
TWGLRPSVVL GHSLGELAAA YAAGVLDLAD ACALVAARGR LMQALPEVGA
710 720 730 740 750
MAAVEATEEE LRDLLARCDG EVSLAAVNGP GSTVVSGTAT AVDEVVTRLV
760 770 780 790 800
ALGRRTRALN VSHAFHSACM DDALAELREV AAAITYHPPR IPVASNILGR
810 820 830 840 850
LVTGPELGTA DYWVRHARQT VRFDACVRAA HRRGVRTFVE LGPDPVLAGM
860 870 880 890 900
AARCLTDPQV SFTPALRRDR SECGQLMHAV ATAYVRGAAV DWPRVFDGTA
910 920 930 940 950
ARRVELPTYP FQRRRYWLGR AGAAGHAVLA EALPLAGSDE TVVTGRLSLA
960 970 980 990 1000
ALPWLADHVV AGRILFPGTG FVDLALHAGG RVGYPRLRDL TLHAPLVLDP
1010 1020 1030 1040 1050
AQTVRVQVRI TPGAGGQDGA AVAVYARADE DGWTCHASGG LESRASAEFD
1060 1070 1080 1090 1100
LRRWPPPDAV PVDITGLYGA LAERGYDFGA AFRGLRAAWR RGDELFGEVV
1110 1120 1130 1140 1150
LPEPASVDAR RYALHPALLD GALHTVGAAA PSGAAAPSEA ARPLLLPFAW
1160 1170 1180 1190 1200
SACSCQPPGA SGLRVRIDTS VPGSISVQLA DLAGDPVAAA ESLVLRPASG
1210 1220 1230 1240 1250
DRVGVTGGTS EHDDALFELD WATTTAVGPT PVAGEWMVLG AGAGTGTDLQ
1260 1270 1280 1290 1300
PTGPVGTGLA GAGVPVRPLP DLAEATGTPP LVLLDCVGEP GAATPQRVRA
1310 1320 1330 1340 1350
TLARALAVVR RWLVEPRWSG SRLMVVTAGA VAAGCDEDVS DLAGAAVWGL
1360 1370 1380 1390 1400
LRSAQAEHPG RFTLVDVDRT PQSWALLPTL VGHPETQFAL RAGQLRVPRL
1410 1420 1430 1440 1450
VRLAGSAEPA AGPLFDVAGT VLVTGGTGTL GALVARHLVA AHGIRRLVLV
1460 1470 1480 1490 1500
SRRGSRAPGA DELVAELSAA GPAVEVVAAD VAERDEVARV LAAVDRAGPL
1510 1520 1530 1540 1550
TGVVHTAGVL DDGTVLTLTP QRLERVLRAK ADAAWHLHEL TRDRPSTAFV
1560 1570 1580 1590 1600
TFSSAAGLLG NAGQGNYAAA NTFLDALVAH RRSLGLAGVS VAWGRWERTS
1610 1620 1630 1640 1650
AMTAGLGAVE LARQARDGFR PLSDEQGLAL FDAAVAAGRP LVAALPMRVT
1660 1670 1680 1690 1700
ALRDETGTVP PILTRLAPPS PAVVAPAADE GGRSGNLDLA GLDPAARRRA
1710 1720 1730 1740 1750
LLDLVRGRTA VVLGHHAAEE VEVDRPFLEV GFDSLMATQL RNALAAATGW
1760 1770 1780 1790 1800
QLPSTVVFDQ PTPRELAEYL DELGPPVSRA GATGGSAGAV GPTGEDSIGV
1810 1820 1830 1840 1850
LFRRAVRDGR RDQGFDLLHA AAALRPQFDE ASELAGAPEP VRLADGPGAI
1860 1870 1880 1890 1900
RLACVPAPMG MGGAHQYARF AERFRAVRPV LAVPMPGFSA KEPLPASPEA
1910 1920 1930 1940 1950
AVEVLAGQLR PLAESGPLVL VGYSSGGVFA NAAAHRLEQL GCRVAGLVLL
1960 1970 1980 1990 2000
DTYQPDTTAI ANFISPMLDG LFEREGSFGP FTTARLTGMA RYARLLDRCA
2010 2020 2030 2040 2050
VGEPDVPVLF VRPGKLFVLD GQPQPDDDTW RASWRRMDTV REVPGNHFTM
2060 2070
LEDEVAATAE VVESWIAGLR
Length:2,070
Mass (Da):217,337
Last modified:June 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF65D5A6FF925665D
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB089954 Genomic DNA Translation: BAC57032.1

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB089954 Genomic DNA Translation: BAC57032.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein family/group databases

ESTHERimicgr-MYCAV Thioesterase

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-18363

Family and domain databases

Gene3Di1.10.1200.10, 1 hit
3.10.129.110, 1 hit
3.40.366.10, 1 hit
3.40.47.10, 1 hit
3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR001227 Ac_transferase_dom_sf
IPR036736 ACP-like_sf
IPR014043 Acyl_transferase
IPR016035 Acyl_Trfase/lysoPLipase
IPR032821 KAsynt_C_assoc
IPR018201 Ketoacyl_synth_AS
IPR014031 Ketoacyl_synth_C
IPR014030 Ketoacyl_synth_N
IPR016036 Malonyl_transacylase_ACP-bd
IPR036291 NAD(P)-bd_dom_sf
IPR041314 PikA4_N
IPR020801 PKS_acyl_transferase
IPR020841 PKS_Beta-ketoAc_synthase_dom
IPR020807 PKS_dehydratase
IPR042104 PKS_dehydratase_sf
IPR013968 PKS_KR
IPR020806 PKS_PP-bd
IPR020802 PKS_thioesterase
IPR009081 PP-bd_ACP
IPR006162 Ppantetheine_attach_site
IPR001031 Thioesterase
IPR016039 Thiolase-like
PfamiView protein in Pfam
PF00698 Acyl_transf_1, 1 hit
PF16197 KAsynt_C_assoc, 1 hit
PF00109 ketoacyl-synt, 1 hit
PF02801 Ketoacyl-synt_C, 1 hit
PF08659 KR, 1 hit
PF18605 PikAIV_N, 1 hit
PF00550 PP-binding, 1 hit
PF14765 PS-DH, 1 hit
PF00975 Thioesterase, 1 hit
SMARTiView protein in SMART
SM00827 PKS_AT, 1 hit
SM00826 PKS_DH, 1 hit
SM00825 PKS_KS, 1 hit
SM00823 PKS_PP, 1 hit
SM00824 PKS_TE, 1 hit
SUPFAMiSSF51735 SSF51735, 2 hits
SSF52151 SSF52151, 1 hit
SSF53474 SSF53474, 1 hit
SSF53901 SSF53901, 1 hit
SSF55048 SSF55048, 1 hit
PROSITEiView protein in PROSITE
PS00606 B_KETOACYL_SYNTHASE, 1 hit
PS50075 CARRIER, 1 hit
PS00012 PHOSPHOPANTETHEINE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ83WE6_MICGR
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q83WE6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: December 11, 2019
This is version 93 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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