Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 104 (10 Feb 2021)
Sequence version 1 (01 Jun 2003)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Glycosyl hydrolase, family 38

Gene

EF_1707

Organism
Enterococcus faecalis (strain ATCC 700802 / V583)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi247Calcium; via carbonyl oxygenCombined sources1
Metal bindingi250Calcium; via carbonyl oxygenCombined sources1
Metal bindingi253Calcium; via carbonyl oxygenCombined sources1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosidaseARBA annotation, Hydrolase
LigandCalciumCombined sources, Metal-bindingCombined sourcesARBA annotation

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
EFAE226185:G1G0C-1685-MONOMER

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
GH38, Glycoside Hydrolase Family 38

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Glycosyl hydrolase, family 38Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:EF_1707Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEnterococcus faecalis (strain ATCC 700802 / V583)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri226185 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001415 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi354 ↔ 356Combined sources

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
226185.EF_1707

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q834E8

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini296 – 369Alpha-mann_midInterPro annotationAdd BLAST74

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glycosyl hydrolase 38 family.ARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG0383, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_003442_2_1_9

Identification of Orthologs from Complete Genome Data

More...
OMAi
VVTRPNK

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1270.50, 1 hit
3.20.110.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011013, Gal_mutarotase_sf_dom
IPR041509, GH38_beta-1
IPR041147, GH38_C
IPR011330, Glyco_hydro/deAcase_b/a-brl
IPR011682, Glyco_hydro_38_C
IPR015341, Glyco_hydro_38_cen
IPR037094, Glyco_hydro_38_cen_sf
IPR000602, Glyco_hydro_38_N
IPR027291, Glyco_hydro_38_N_sf
IPR028995, Glyco_hydro_57/38_cen_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09261, Alpha-mann_mid, 1 hit
PF17677, Glyco_hydro38C2, 1 hit
PF18438, Glyco_hydro_38, 1 hit
PF07748, Glyco_hydro_38C, 1 hit
PF01074, Glyco_hydro_38N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00872, Alpha-mann_mid, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF74650, SSF74650, 1 hit
SSF88688, SSF88688, 1 hit
SSF88713, SSF88713, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q834E8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTKKKVYIVS HSHWDREWYL PYEEHHMRLI ELVDNVLDLI ENDPEFNSFH
60 70 80 90 100
LDGQTIILDD YLQVRPEKKE AVKKAVQAGK LKIGPFYILQ DDFLISSESN
110 120 130 140 150
VRNMLIGHLE SQKWGAPVQL GYFPDTFGNM GQTPQMMQLA NLPAAAFGRG
160 170 180 190 200
VKPIGFDNQV LESDYSSQYS EMWWEGPDQT KIFGLLFANW YSNGNEIPSE
210 220 230 240 250
KEAAIAFWKQ KLADVERYAS TNHLLMMNGV DHQPVQRDIT KAIALANELF
260 270 280 290 300
PEYEFIHSNF DDYLKAVQEE LPEDLGTVTG ELTSQETDGW YTLANTSSAR
310 320 330 340 350
VYLKQWNTKV QRQLENIAEP LAAMAYEVTG DYPHDQFDYA WKTLLQNHPH
360 370 380 390 400
DSICGCSVDE VHRGMMTRFE NANDVGHFLA DEATRQLTEA IDTSVFPEKA
410 420 430 440 450
HPFVLFNTSG YQKTEVVTVE VEIERLPFYT GKPEDLYHEL KQKATPDYQV
460 470 480 490 500
IDPTGKAVAS RIVKEDVRFG YDLPKDAFRQ PYMAKYLTVE LSVKEMAPFS
510 520 530 540 550
WDSFALIQGE TKAFEGSLLA QPATNEMENE FIQVKIENNG SLTIADKKTG
560 570 580 590 600
ETFSKLLTFE DTGDIGNEYI FFKPTEDQGI TTENVTAEIT NKENSPVKAS
610 620 630 640 650
YQIKQTVMLP VAADERLEEE QKAVREFRER LAQRSTTLRP FEITTMVTMI
660 670 680 690 700
KESNQLFFET TINNQIKDHR LRVLFPTGMV TETHEADSIY EVVTRPNQVS
710 720 730 740 750
DTWENPTNPQ HQQAFVNVHD QNKGVTIFNE GLNEYEVLAD GTIAVTLIRC
760 770 780 790 800
VGELGDWGYF ATPEAQCQGE YTFKYGLSLH GKPEERFATY QQAYSAQIPF
810 820 830 840 850
TAATTARHEG KLAPNHVYLT TAEGPIGWTA VKRQEQTNHL VVRGFNLTAQ
860 870 880 890
NIPCELHKET QPATCLTNVL EEPLTPAIEV DAPLRPFEIR TWRFEK
Length:896
Mass (Da):102,244
Last modified:June 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i727A5CDC35B297B8
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE016830 Genomic DNA Translation: AAO81483.1

NCBI Reference Sequences

More...
RefSeqi
NP_815413.1, NC_004668.1
WP_002369316.1, NZ_KE136528.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAO81483; AAO81483; EF_1707

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
efa:EF1707

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|226185.45.peg.1805

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016830 Genomic DNA Translation: AAO81483.1
RefSeqiNP_815413.1, NC_004668.1
WP_002369316.1, NZ_KE136528.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3LVTX-ray2.55A1-896[»]
5KBPX-ray2.40A/B1-896[»]
SMRiQ834E8
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

STRINGi226185.EF_1707

Protein family/group databases

CAZyiGH38, Glycoside Hydrolase Family 38

Genome annotation databases

EnsemblBacteriaiAAO81483; AAO81483; EF_1707
KEGGiefa:EF1707
PATRICifig|226185.45.peg.1805

Phylogenomic databases

eggNOGiCOG0383, Bacteria
HOGENOMiCLU_003442_2_1_9
OMAiVVTRPNK

Enzyme and pathway databases

BioCyciEFAE226185:G1G0C-1685-MONOMER

Family and domain databases

Gene3Di1.20.1270.50, 1 hit
3.20.110.10, 1 hit
InterProiView protein in InterPro
IPR011013, Gal_mutarotase_sf_dom
IPR041509, GH38_beta-1
IPR041147, GH38_C
IPR011330, Glyco_hydro/deAcase_b/a-brl
IPR011682, Glyco_hydro_38_C
IPR015341, Glyco_hydro_38_cen
IPR037094, Glyco_hydro_38_cen_sf
IPR000602, Glyco_hydro_38_N
IPR027291, Glyco_hydro_38_N_sf
IPR028995, Glyco_hydro_57/38_cen_sf
PfamiView protein in Pfam
PF09261, Alpha-mann_mid, 1 hit
PF17677, Glyco_hydro38C2, 1 hit
PF18438, Glyco_hydro_38, 1 hit
PF07748, Glyco_hydro_38C, 1 hit
PF01074, Glyco_hydro_38N, 1 hit
SMARTiView protein in SMART
SM00872, Alpha-mann_mid, 1 hit
SUPFAMiSSF74650, SSF74650, 1 hit
SSF88688, SSF88688, 1 hit
SSF88713, SSF88713, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ834E8_ENTFA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q834E8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: February 10, 2021
This is version 104 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again