UniProtKB - Q833W9 (LACC_ENTFA)
Protein
Tagatose-6-phosphate kinase
Gene
lacC
Organism
Enterococcus faecalis (strain ATCC 700802 / V583)
Status
Functioni
Catalytic activityi
- EC:2.7.1.144UniRule annotation
: D-tagatose 6-phosphate degradation Pathwayi
This protein is involved in step 1 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-phosphate.UniRule annotationProteins known to be involved in the 2 steps of the subpathway in this organism are:
- Tagatose-6-phosphate kinase (lacC), Tagatose-6-phosphate kinase (fruK-2), Tagatose-6-phosphate kinase (fruK-1)
- Tagatose 1,6-diphosphate aldolase 2 (lacD2), Tagatose 1,6-diphosphate aldolase 1 (lacD1)
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-phosphate, the pathway D-tagatose 6-phosphate degradation and in Carbohydrate metabolism.
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- tagatose-6-phosphate kinase activity Source: UniProtKB-UniRule
GO - Biological processi
- D-tagatose 6-phosphate catabolic process Source: UniProtKB-UniPathway
- lactose catabolic process via tagatose-6-phosphate Source: UniProtKB-UniRule
Keywordsi
Molecular function | Kinase, Transferase |
Biological process | Lactose metabolism |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | EFAE226185:G1G0C-1778-MONOMER |
UniPathwayi | UPA00704;UER00715 |
Names & Taxonomyi
Protein namesi | Recommended name: Tagatose-6-phosphate kinaseUniRule annotation (EC:2.7.1.144UniRule annotation)Alternative name(s): PhosphotagatokinaseUniRule annotation |
Gene namesi | Name:lacCUniRule annotation Ordered Locus Names:EF_1806 |
Organismi | Enterococcus faecalis (strain ATCC 700802 / V583) |
Taxonomic identifieri | 226185 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Lactobacillales › Enterococcaceae › Enterococcus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000203914 | 1 – 313 | Tagatose-6-phosphate kinaseAdd BLAST | 313 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | Q833W9 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q833W9 |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | COG1105, Bacteria |
HOGENOMi | CLU_050013_5_0_9 |
OMAi | GHVNMAH |
Family and domain databases
CDDi | cd01164, FruK_PfkB_like, 1 hit |
Gene3Di | 3.40.1190.20, 1 hit |
HAMAPi | MF_01557, LacC, 1 hit |
InterProi | View protein in InterPro IPR002173, Carboh/pur_kinase_PfkB_CS IPR005926, LacC IPR011611, PfkB_dom IPR029056, Ribokinase-like IPR017583, Tagatose/fructose_Pkinase |
Pfami | View protein in Pfam PF00294, PfkB, 1 hit |
PIRSFi | PIRSF000535, 1PFK/6PFK/LacC, 1 hit |
SUPFAMi | SSF53613, SSF53613, 1 hit |
TIGRFAMsi | TIGR03168, 1-PFK, 1 hit |
PROSITEi | View protein in PROSITE PS00583, PFKB_KINASES_1, 1 hit PS00584, PFKB_KINASES_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q833W9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIVTVTMNPS IDISYLLDHL KLDTVNRTSQ VTKTPGGKGL NVTRVIHDLG
60 70 80 90 100
GDVIATGVLG GFHGAFIANE LKKANIPQAF TSIKEETRDS IAILHEGNQT
110 120 130 140 150
EILEAGPTVS PEEISNFLEN FDQLIKQAEI VTISGSLAKG LPSDFYQELV
160 170 180 190 200
QKAHAQEVKV LLDTSGDSLR QVLQGPWKPY LIKPNLEELE GLLGQDFSEN
210 220 230 240 250
PLAAVQTALT KPMFAGIEWI VISLGKDGAI AKHHDQFYRV KIPTIQAKNP
260 270 280 290 300
VGSGDATIAG LAYGLAKDAP AAELLKWGMA AGMANAQERM TGHVDVENVK
310
KHLMNIQVVE IAK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE016830 Genomic DNA Translation: AAO81574.1 |
RefSeqi | NP_815504.1, NC_004668.1 WP_010706669.1, NZ_KE136528.1 |
Genome annotation databases
EnsemblBacteriai | AAO81574; AAO81574; EF_1806 |
KEGGi | efa:EF1806 |
PATRICi | fig|226185.45.peg.1712 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE016830 Genomic DNA Translation: AAO81574.1 |
RefSeqi | NP_815504.1, NC_004668.1 WP_010706669.1, NZ_KE136528.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
2AWD | X-ray | 2.00 | A/B | 2-313 | [»] | |
2F02 | X-ray | 1.90 | A/B | 2-313 | [»] | |
SMRi | Q833W9 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 226185.EF_1806 |
Protocols and materials databases
DNASUi | 1200692 |
Genome annotation databases
EnsemblBacteriai | AAO81574; AAO81574; EF_1806 |
KEGGi | efa:EF1806 |
PATRICi | fig|226185.45.peg.1712 |
Phylogenomic databases
eggNOGi | COG1105, Bacteria |
HOGENOMi | CLU_050013_5_0_9 |
OMAi | GHVNMAH |
Enzyme and pathway databases
UniPathwayi | UPA00704;UER00715 |
BioCyci | EFAE226185:G1G0C-1778-MONOMER |
Miscellaneous databases
EvolutionaryTracei | Q833W9 |
Family and domain databases
CDDi | cd01164, FruK_PfkB_like, 1 hit |
Gene3Di | 3.40.1190.20, 1 hit |
HAMAPi | MF_01557, LacC, 1 hit |
InterProi | View protein in InterPro IPR002173, Carboh/pur_kinase_PfkB_CS IPR005926, LacC IPR011611, PfkB_dom IPR029056, Ribokinase-like IPR017583, Tagatose/fructose_Pkinase |
Pfami | View protein in Pfam PF00294, PfkB, 1 hit |
PIRSFi | PIRSF000535, 1PFK/6PFK/LacC, 1 hit |
SUPFAMi | SSF53613, SSF53613, 1 hit |
TIGRFAMsi | TIGR03168, 1-PFK, 1 hit |
PROSITEi | View protein in PROSITE PS00583, PFKB_KINASES_1, 1 hit PS00584, PFKB_KINASES_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | LACC_ENTFA | |
Accessioni | Q833W9Primary (citable) accession number: Q833W9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 10, 2006 |
Last sequence update: | June 1, 2003 | |
Last modified: | December 2, 2020 | |
This is version 103 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families