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Protein

Spermidine/putrescine import ATP-binding protein PotA

Gene

potA

Organism
Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.UniRule annotation

Catalytic activityi

ATP + H2O + polyamine(Out) = ADP + phosphate + polyamine(In).UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi37 – 44ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase
Biological processTransport
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Spermidine/putrescine import ATP-binding protein PotAUniRule annotation (EC:3.6.3.31UniRule annotation)
Gene namesi
Name:potAUniRule annotation
Ordered Locus Names:BC_1286
OrganismiBacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)
Taxonomic identifieri226900 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000001417 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002861931 – 327Spermidine/putrescine import ATP-binding protein PotAAdd BLAST327

Proteomic databases

PRIDEiQ81GC1

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).UniRule annotation

Protein-protein interaction databases

STRINGi226900.BC1286

Structurei

3D structure databases

ProteinModelPortaliQ81GC1
SMRiQ81GC1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 235ABC transporterUniRule annotationAdd BLAST231

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105C53 Bacteria
COG3842 LUCA
KOiK11072
OMAiPYRRNVN

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR017879 ABC_Sperm/Put_ATP-bd_PotA
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR008995 Mo/tungstate-bd_C_term_dom
IPR027417 P-loop_NTPase
IPR013611 Transp-assoc_OB_typ2
PfamiView protein in Pfam
PF00005 ABC_tran, 1 hit
PF08402 TOBE_2, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF50331 SSF50331, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit
PS51305 POTA, 1 hit

Sequencei

Sequence statusi: Complete.

Q81GC1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKKIIKVEAV EKHFGNQVII PPLSLDIKEG EFLTILGPSG CGKTTLLRMI
60 70 80 90 100
AGFETPTKGN LLLDDERIND LPPYKRHMNL VFQHYALFPH MTVEKNICFG
110 120 130 140 150
MKMQKVSAAE QKERAEEAMR LTQLLEFRNR KPAKLSGGQQ QRVAIARAIV
160 170 180 190 200
NNPRVLLLDE PLGALDFKLR KDLQRELKNL QRNLGITFIY VTHDQEEAMS
210 220 230 240 250
MSDRIVVMNK GHIEQIGTPK EIYNKPKTLF VATFIGENNI VKNGEGYVAI
260 270 280 290 300
RPENVKVRSV EEPILKEYHL GHIEDIEFVG NMEKLYVRDE KTSELLMAYQ
310 320
TAEEAAQWSI GDNVYVGWEQ EDEVTLN
Length:327
Mass (Da):37,405
Last modified:June 1, 2003 - v1
Checksum:iDF598A3FCF03C6EE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016877 Genomic DNA Translation: AAP08269.1
RefSeqiNP_831068.1, NC_004722.1
WP_000720333.1, NC_004722.1

Genome annotation databases

EnsemblBacteriaiAAP08269; AAP08269; BC_1286
GeneIDi1203635
KEGGibce:BC1286
PATRICifig|226900.8.peg.1259

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016877 Genomic DNA Translation: AAP08269.1
RefSeqiNP_831068.1, NC_004722.1
WP_000720333.1, NC_004722.1

3D structure databases

ProteinModelPortaliQ81GC1
SMRiQ81GC1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi226900.BC1286

Proteomic databases

PRIDEiQ81GC1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAP08269; AAP08269; BC_1286
GeneIDi1203635
KEGGibce:BC1286
PATRICifig|226900.8.peg.1259

Phylogenomic databases

eggNOGiENOG4105C53 Bacteria
COG3842 LUCA
KOiK11072
OMAiPYRRNVN

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR017879 ABC_Sperm/Put_ATP-bd_PotA
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR008995 Mo/tungstate-bd_C_term_dom
IPR027417 P-loop_NTPase
IPR013611 Transp-assoc_OB_typ2
PfamiView protein in Pfam
PF00005 ABC_tran, 1 hit
PF08402 TOBE_2, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF50331 SSF50331, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit
PS51305 POTA, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPOTA_BACCR
AccessioniPrimary (citable) accession number: Q81GC1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: June 1, 2003
Last modified: November 7, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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