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Protein
Submitted name:

Interferon alpha 16

Gene

Ifna16

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

  • cytokine activity Source: GO_Central
  • type I interferon receptor binding Source: GO_Central

GO - Biological processi

Keywordsi

Molecular functionCytokineUniRule annotationSAAS annotation
Biological processAntiviral defenseUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-MMU-909733 Interferon alpha/beta signaling
R-MMU-912694 Regulation of IFNA signaling

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon alpha 16Imported
Submitted name:
Interferon alpha 6TImported
Submitted name:
MCG146422Imported
Gene namesi
Name:Ifna16Imported
Synonyms:Gm13280Imported, Ifna6TImported, OTTMUSG00000011275Imported
ORF Names:mCG_146422Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:3649260 Ifna16

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_501509893824 – 189Sequence analysisAdd BLAST166

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000078355 Expressed in 4 organ(s), highest expression level in spleen

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000100779

Family & Domainsi

Sequence similaritiesi

Belongs to the alpha/beta interferon family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410J735 Eukaryota
ENOG410ZH91 LUCA
GeneTreeiENSGT00760000119150
HOGENOMiHOG000230500
HOVERGENiHBG052086
OMAiRKYSPCA
OrthoDBiEOG091G0PSY
TreeFamiTF336177

Family and domain databases

CDDicd00095 IFab, 1 hit
InterProiView protein in InterPro
IPR009079 4_helix_cytokine-like_core
IPR000471 Interferon_alpha/beta/delta
PANTHERiPTHR11691 PTHR11691, 1 hit
PfamiView protein in Pfam
PF00143 Interferon, 1 hit
PRINTSiPR00266 INTERFERONAB
SMARTiView protein in SMART
SM00076 IFabd, 1 hit
SUPFAMiSSF47266 SSF47266, 1 hit
PROSITEiView protein in PROSITE
PS00252 INTERFERON_A_B_D, 1 hit

Sequencei

Sequence statusi: Complete.

Q810G1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MARLCAFLMV LAVMSYWSTC SLGCDLPQTH KLRNKRALTL LIQMRRLSPL
60 70 80 90 100
SCLKDRKDFG FPQEKVDTLK IQKEKAIPVL SEVTQQILNI FTSKDSSAAW
110 120 130 140 150
DATLLDTFCN DLYQQLNDLQ ACLVQQVRLQ EPPLTQEVSL LAVRKYFHRI
160 170 180
TVYLREKKHS PCAWEVVRAE VWRALSSSAN VLGRLREEK
Length:189
Mass (Da):21,798
Last modified:June 1, 2003 - v1
Checksum:iBBDCD562FE99FF70
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL928605 Genomic DNA No translation available.
AY220465 Genomic DNA Translation: AAO64458.1
CH466527 Genomic DNA Translation: EDL30969.1
RefSeqiNP_996750.1, NM_206867.1
UniGeneiMm.377246

Genome annotation databases

EnsembliENSMUST00000105148; ENSMUSP00000100779; ENSMUSG00000078355
GeneIDi230398
KEGGimmu:230398
UCSCiuc008tnh.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL928605 Genomic DNA No translation available.
AY220465 Genomic DNA Translation: AAO64458.1
CH466527 Genomic DNA Translation: EDL30969.1
RefSeqiNP_996750.1, NM_206867.1
UniGeneiMm.377246

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000100779

Protocols and materials databases

DNASUi230398
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000105148; ENSMUSP00000100779; ENSMUSG00000078355
GeneIDi230398
KEGGimmu:230398
UCSCiuc008tnh.1 mouse

Organism-specific databases

CTDi3449
MGIiMGI:3649260 Ifna16

Phylogenomic databases

eggNOGiENOG410J735 Eukaryota
ENOG410ZH91 LUCA
GeneTreeiENSGT00760000119150
HOGENOMiHOG000230500
HOVERGENiHBG052086
OMAiRKYSPCA
OrthoDBiEOG091G0PSY
TreeFamiTF336177

Enzyme and pathway databases

ReactomeiR-MMU-909733 Interferon alpha/beta signaling
R-MMU-912694 Regulation of IFNA signaling

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000078355 Expressed in 4 organ(s), highest expression level in spleen

Family and domain databases

CDDicd00095 IFab, 1 hit
InterProiView protein in InterPro
IPR009079 4_helix_cytokine-like_core
IPR000471 Interferon_alpha/beta/delta
PANTHERiPTHR11691 PTHR11691, 1 hit
PfamiView protein in Pfam
PF00143 Interferon, 1 hit
PRINTSiPR00266 INTERFERONAB
SMARTiView protein in SMART
SM00076 IFabd, 1 hit
SUPFAMiSSF47266 SSF47266, 1 hit
PROSITEiView protein in PROSITE
PS00252 INTERFERON_A_B_D, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ810G1_MOUSE
AccessioniPrimary (citable) accession number: Q810G1
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: November 7, 2018
This is version 133 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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